Differences in the lipoprotein distribution of halofantrine are regulated by lipoprotein apolar lipid and protein concentration and lipid transfer protein I activity: In vitro studies in normolipidemic and dyslipidemic human plasmas

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Differences in the lipoprotein distribution of halofantrine are regulated by lipoprotein apolar lipid and protein concentration and lipid transfer protein I activity: In vitro studies in normolipidemic and dyslipidemic human plasmas is …
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scholarly articleQ13442814

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P356DOI10.1021/JS980353K
P698PubMed publication ID9950636

P2093author name stringWasan KM
Charman WN
Porter CJ
Ramaswamy M
McIntosh MP
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Differences in lipoprotein lipid concentration and composition modify the plasma distribution of cyclosporineQ74061558
THE DISTRIBUTION AND CHEMICAL COMPOSITION OF ULTRACENTRIFUGALLY SEPARATED LIPOPROTEINS IN HUMAN SERUMQ29391553
The antimalarial drug halofantrine is bound mainly to low and high density lipoproteins in human serumQ34347239
Clinical pharmacokinetics of halofantrineQ39121208
Concentrations in serum and distribution in tissue of free and liposomal amphotericin B in rats during continuous intralipid infusionQ40286515
Effect of altered serum lipid concentrations on the IC50 of halofantrine against Plasmodium falciparumQ41926954
Cardiac complications of halofantrine: a prospective study of 20 patientsQ42276310
Distribution of free and liposomal annamycin within human plasma is regulated by plasma triglyceride concentrations but not by lipid transfer protein.Q54163527
A simplified liquid chromatography assay for the quantitation of halofantrine and desbutylhalofantrine in plasma and identification of a degradation product of desbutylhalofantrine formed under alkaline conditionsQ57836023
Pharmacokinetics, tissue distribution, and toxicity of free and liposomal amphotericin B in diabetic ratsQ68727730
Differences in lipoprotein concentration and composition modify the plasma distribution of free and liposomal annamycinQ71221688
Role of lipoproteins and erythrocytes in the in vitro binding and distribution of cyclosporin A in the bloodQ72541756
Decreased toxicity of liposomal amphotericin B due to association of amphotericin B with high-density lipoproteins: role of lipid transfer proteinQ72818155
Human plasma distribution of free paclitaxel and paclitaxel associated with diblock copolymersQ73236915
P433issue2
P407language of work or nameEnglishQ1860
P921main subjecthalofantrineQ947595
P1104number of pages6
P304page(s)185-190
P577publication date1999-02-01
P1433published inJournal of Pharmaceutical SciencesQ3186933
P1476titleDifferences in the lipoprotein distribution of halofantrine are regulated by lipoprotein apolar lipid and protein concentration and lipid transfer protein I activity: in vitro studies in normolipidemic and dyslipidemic human plasmas
P478volume88

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