Rat liver mitochondrial and microsomal tests for the assessment of quinone toxicity

scientific article published in February 1994

Rat liver mitochondrial and microsomal tests for the assessment of quinone toxicity is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1002/ETC.5620130215

P2093author name stringDavid R Bevan
Gregory D Boardman
Andrea M. Dietrich
Lisa A Bramble
P2860cites workSpontaneous mutagenesis and oxidative damage to DNA in Salmonella typhimuriumQ34377034
Mutagenicity of quinones: pathways of metabolic activation and detoxificationQ36255339
Quinone chemistry and toxicityQ36748286
Overview of enzyme systems involved in bio-reduction of drugs and in redox cyclingQ38155821
Glutathione depleting agents and lipid peroxidationQ39684618
Production of superoxide radicals and hydrogen peroxide by NADH-ubiquinone reductase and ubiquinol-cytochrome c reductase from beef-heart mitochondriaQ40082378
Lipid peroxide formation in microsomes. General considerationsQ41876948
Mechanisms of toxicity of naphthoquinones to isolated hepatocytesQ44849526
Mechanisms of toxicity of 2- and 5-hydroxy-1,4-naphthoquinone; absence of a role for redox cycling in the toxicity of 2-hydroxy-1,4-naphthoquinone to isolated hepatocytesQ44937533
Mutagenicity of natural naphthoquinones and benzoquinones in the Salmonella/microsome testQ50210626
Substituted 1,4-naphthoquinones vs. the ascitic sarcoma 180 of mice.Q52706910
Discriminant analysis and structure-activity relationships. 1. Naphthoquinones.Q52796065
Potential use of human tissues for toxicity research and testing.Q53516514
Quinones as mutagens, carcinogens, and anticancer agents: introduction and overview.Q53546188
Relationship between inhibition of mitochondrial respiration by naphthoquinones, their antitumor activity, and their redox potential.Q53733326
Quinone toxicity in hepatocytes without oxidative stress.Q54419485
Streptonigrin. 1. Structure-activity relationships among simple bicyclic analogues. Rate dependence of DNA degradation on quinone reduction potential.Q54777293
Animal Rights and Modern ToxicologyQ56679612
Induction of cell damage by menadione and benzo(a)-pyrene-3,6-quinone in cultures of adult rat hepatocytes and human fibroblastsQ58862368
Induction of dna damage by menadione (2-methyl-1,4-naphthoquinone) in primary cultures of rat hepatocytesQ58862376
Biochemistry of Oxidative StressQ59151803
Mitochondrial response to chlorophenols as a short-term toxicity assayQ61985141
Method of determining oxygen concentrations in biological media, suitable for calibration of the oxygen electrodeQ68608323
Radical-pair energetics and decay mechanisms in reaction centers containing anthraquinones, naphthoquinones or benzoquinones in place of ubiquinoneQ68888502
Alternative testing methodologies--scientific updateQ69458948
Comparison of the effects on mitochondrial function of a series of 2-methyl substituted 1,4-naphthoquinones to their 6-methyl counterpartsQ69585999
Aromatic substituent constants for structure-activity correlationsQ69600149
2-Bromohydroquinone-induced toxicity to rabbit renal proximal tubules: evidence against oxidative stressQ69621714
Redox cycling and sulphydryl arylation; their relative importance in the mechanism of quinone cytotoxicity to isolated hepatocytesQ69825811
One-electron oxidation-reduction properties of hepatic NADH-cytochrome b5 reductaseQ70211585
A redox cycling mechanism of action for 2,3-dichloro-1,4-naphthoquinone with mitochondrial membranes and the role of sulfhydryl groupsQ70702541
In vitro stimulation by paraquat of reactive oxygen-mediated lipid peroxidation in rat lung microsomesQ70926324
Pulse radiolysis studies of antitumor quinones: Radical lifetimes, reactivity with oxygen, and one-electron reduction potentialsQ70933229
On the relationship between Ca2+ efflux and membrane damage during t-butylhydroperoxide metabolism by liver mitochondriaQ71037326
Relationship of the single-electron reduction potential of quinones to their reduction by flavoproteinsQ71520102
Studies on the microsomal mixed-function oxidase system: mechanism of action of hepatic NADPH-cytochrome P-450 reductaseQ71545400
P433issue2
P921main subjectenvironmental chemistryQ321355
P304page(s)307-316
P577publication date1994-02-01
P1433published inEnvironmental Toxicology and ChemistryQ3726418
P1476titleRat liver mitochondrial and microsomal tests for the assessment of quinone toxicity
P478volume13

Reverse relations

Q52563130The use of the mitochondrial transmembrane electric potential as an effective biosensor in ecotoxicological research.cites workP2860

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