Molecular genetic alterations in thyroid transcription factor 1-negative lung adenocarcinoma in cytology specimens: A subset with aggressive behavior and a poor prognosis

scientific article published on 10 September 2018

Molecular genetic alterations in thyroid transcription factor 1-negative lung adenocarcinoma in cytology specimens: A subset with aggressive behavior and a poor prognosis is …
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scholarly articleQ13442814

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P356DOI10.1002/CNCY.22048
P698PubMed publication ID30199148

P50authorZahra MalekiQ43091441
P2093author name stringChristopher J VandenBussche
Erika F Rodriguez
Sayanan Chowsilpa
P2860cites workExpression of thyroid transcription factor-1(TTF-1) in fetal and neonatal human lungQ24336193
Epidermal growth factor receptor (EGFR) mutations are exceptionally rare in thyroid transcription factor (TTF-1)-negative adenocarcinomas of the lung.Q34781380
Clinical validation of KRAS, BRAF, and EGFR mutation detection using next-generation sequencingQ35095944
Thyroid transcription factor-1 (TTF-1/Nkx2.1/TITF1) gene regulation in the lungQ37336056
Pathological diagnosis and classification of lung cancer in small biopsies and cytology: strategic management of tissue for molecular testingQ37866183
Value of thyroid transcription factor-1 immunostaining in tumor diagnosis: a review and updateQ38005307
Cyto-histologic agreement in pathologic subtyping of non small cell lung carcinoma: review of 602 fine needle aspirates with follow-up surgical specimens over a nine year period and analysis of factors underlying failure to subtypeQ38015476
Thyroid transcription factor 1 expression is associated with outcome of patients with non-squamous non-small cell lung cancer treated with pemetrexed-based chemotherapyQ38952088
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Morphologic Accuracy in Differentiating Primary Lung Adenocarcinoma From Squamous Cell Carcinoma in Cytology SpecimensQ39463253
Associations between TS, TTF-1, FR-α, FPGS, and overall survival in patients with advanced non-small-cell lung cancer receiving pemetrexed plus carboplatin or gemcitabine plus carboplatin as first-line chemotherapyQ43663223
Adequacy of endobronchial ultrasound transbronchial needle aspiration samples in the subtyping of non-small cell lung cancerQ45734469
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Molecular Alterations in Patients with Pulmonary Adenocarcinoma Presenting with Malignant Pleural Effusion at the First Diagnosis.Q50627148
Immunohistochemical algorithm for differentiation of lung adenocarcinoma and squamous cell carcinoma based on large series of whole-tissue sections with validation in small specimens.Q51563657
Subclassification of non-small cell lung carcinomas lacking morphologic differentiation on biopsy specimens: Utility of an immunohistochemical panel containing TTF-1, napsin A, p63, and CK5/6.Q51624241
Pulmonary Non-Small Cell Carcinoma With Morphologic Features of Adenocarcinoma or "Non-Small Cell Carcinoma Favor Adenocarcinoma" in Cytologic Specimens Share Similar Clinical and Molecular Genetic Characteristics.Q52720288
High incidence of EGFR mutations in Korean men smokers with no intratumoral heterogeneity of lung adenocarcinomas: correlation with histologic subtypes, EGFR/TTF-1 expressions, and clinical features.Q54329863
Refining the diagnosis and EGFR status of non-small cell lung carcinoma in biopsy and cytologic material, using a panel of mucin staining, TTF-1, cytokeratin 5/6, and P63, and EGFR mutation analysis.Q54446617
A single EBUS-TBNA procedure can support a large panel of immunohistochemical stains, specific diagnostic subtyping, and multiple gene analyses in the majority of non–small cell lung cancer casesQ62081867
Prognostic significance of thyroid transcription factor-1 expression in both early-stage conventional adenocarcinoma and bronchioloalveolar carcinoma of the lungQ75340566
Pathology of lung cancerQ82353394
Immunohistochemical subtyping of nonsmall cell lung cancer not otherwise specified in fine-needle aspiration cytology: a retrospective study of 103 cases with surgical correlationQ83234392
Usefulness of immunohistochemical and histochemical studies in the classification of lung adenocarcinoma and squamous cell carcinoma in cytologic specimensQ84390051
Subtyping of non-small cell lung carcinoma: a comparison of small biopsy and cytology specimensQ84763510
P433issue10
P304page(s)853-859
P577publication date2018-09-10
P1433published inCancer CytopathologyQ13452937
P1476titleMolecular genetic alterations in thyroid transcription factor 1-negative lung adenocarcinoma in cytology specimens: A subset with aggressive behavior and a poor prognosis
P478volume126

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