Louis M Havekes

researcher

Louis M Havekes is …
instance of (P31):
humanQ5

P735given nameLouisQ2897866
LouisQ2897866
P106occupationresearcherQ1650915

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author (P50)
Q430882726-mercaptopurine inhibits atherosclerosis in apolipoprotein e*3-leiden transgenic mice through atheroprotective actions on monocytes and macrophages
Q44011006A low-fat diet has a higher potential than energy restriction to improve high-fat diet-induced insulin resistance in mice
Q35094217A novel EPO receptor agonist improves glucose tolerance via glucose uptake in skeletal muscle in a mouse model of diabetes
Q34608233Acute central neuropeptide Y administration increases food intake but does not affect hepatic very low-density lipoprotein (VLDL) production in mice
Q46427847Acute hepatic steatosis in mice by blocking beta-oxidation does not reduce insulin sensitivity of very-low-density lipoprotein production
Q45270099Acute inhibition of hepatic beta-oxidation in APOE*3Leiden mice does not affect hepatic VLDL secretion or insulin sensitivity
Q60531985An Extrahepatic Receptor-associated Protein-sensitive Mechanism Is Involved in the Metabolism of Triglyceride-rich Lipoproteins
Q34858025Anacetrapib reduces progression of atherosclerosis, mainly by reducing non-HDL-cholesterol, improves lesion stability and adds to the beneficial effects of atorvastatin
Q46902689Anti-atherosclerotic effect of amlodipine, alone and in combination with atorvastatin, in APOE*3-Leiden/hCRP transgenic mice
Q60233040Apo E Polymorphism in Relation to the Expression of Familial Dysbetalipoproteinemia
Q47748338ApoAV reduces plasma triglycerides by inhibiting very low density lipoprotein-triglyceride (VLDL-TG) production and stimulating lipoprotein lipase-mediated VLDL-TG hydrolysis
Q46466019ApoC-III deficiency prevents hyperlipidemia induced by apoE overexpression
Q33242076ApoE plasma levels and risk of cardiovascular mortality in old age
Q36558367ApoE2-associated hypertriglyceridemia is ameliorated by increased levels of apoA-V but unaffected by apoC-III deficiency
Q51014728Apolipoprotein A5 deficiency aggravates high-fat diet-induced obesity due to impaired central regulation of food intake.
Q24299172Apolipoprotein C-I binds free fatty acids and reduces their intracellular esterification
Q45285342Apolipoprotein C3 deficiency results in diet-induced obesity and aggravated insulin resistance in mice
Q24312753Apolipoprotein CI inhibits scavenger receptor BI and increases plasma HDL levels in vivo
Q41825540Apolipoprotein CI overexpression is not a relevant strategy to block cholesteryl ester transfer protein (CETP) activity in CETP transgenic mice
Q60233038Apolipoprotein E Polymorphisms and the Genetic Heterogeneity of Familial Dysbetalipoproteinemia
Q41066976Apolipoprotein E as a risk factor for coronary heart disease: a genetic and molecular biology approach.
Q56451020Apolipoprotein gene cluster on chromosome 19
Q36159060Apolipoproteins modulate the inflammatory response to lipopolysaccharide
Q33976115Aspirin reduces hypertriglyceridemia by lowering VLDL-triglyceride production in mice fed a high-fat diet
Q46160760Bexarotene induces dyslipidemia by increased very low-density lipoprotein production and cholesteryl ester transfer protein-mediated reduction of high-density lipoprotein
Q34744777Both transient and continuous corticosterone excess inhibit atherosclerotic plaque formation in APOE*3-leiden.CETP mice
Q42097167Brown adipose tissue takes up plasma triglycerides mostly after lipolysis
Q46411188Brown adipose tissue volume in healthy lean south Asian adults compared with white Caucasians: a prospective, case-controlled observational study
Q44552197CD36 deficiency increases insulin sensitivity in muscle, but induces insulin resistance in the liver in mice
Q42435953CD36 is important for adipocyte recruitment and affects lipolysis
Q37463344CETP does not affect triglyceride production or clearance in APOE*3-Leiden mice
Q35107299CETP expression reverses the reconstituted HDL-induced increase in VLDL.
Q45810167CNTO736, a novel glucagon-like peptide-1 receptor agonist, ameliorates insulin resistance and inhibits very low-density lipoprotein production in high-fat-fed mice
Q41585297Caspase-1 deficiency in mice reduces intestinal triglyceride absorption and hepatic triglyceride secretion
Q60233042Characterisation and Mode of Inheritance of Apolipoprotein E3-Leiden
Q40237321Cholesteryl ester transfer protein decreases high-density lipoprotein and severely aggravates atherosclerosis in APOE*3-Leiden mice
Q35152229Circulating insulin stimulates fatty acid retention in white adipose tissue via KATP channel activation in the central nervous system only in insulin-sensitive mice
Q39741648Colestilan decreases weight gain by enhanced NEFA incorporation in biliary lipids and fecal lipid excretion
Q48218638Detrimental effects of constant light exposure and high-fat diet on circadian energy metabolism and insulin sensitivity
Q46873973Development of atopic dermatitis in mice transgenic for human apolipoprotein C1.
Q55042300Dietary sphingolipids lower plasma cholesterol and triacylglycerol and prevent liver steatosis in APOE*3Leiden mice.
Q44491764Differential effects of amlodipine and atorvastatin treatment and their combination on atherosclerosis in ApoE*3-Leiden transgenic mice
Q38325289Differential effects of pharmacological liver X receptor activation on hepatic and peripheral insulin sensitivity in lean and ob/ob mice
Q37377010Effect of plasma triglyceride metabolism on lipid storage in adipose tissue: studies using genetically engineered mouse models
Q44353368Effects of amlodipine, atorvastatin and combination of both on advanced atherosclerotic plaque in APOE*3-Leiden transgenic mice
Q46990753Endogenous apoC-I increases hyperlipidemia in apoE-knockout mice by stimulating VLDL production and inhibiting LPL.
Q51497885Endogenous interleukin-10 protects against hepatic steatosis but does not improve insulin sensitivity during high-fat feeding in mice.
Q34764818Establishment of a general NAFLD scoring system for rodent models and comparison to human liver pathology
Q28730126Estimation of activity related energy expenditure and resting metabolic rate in freely moving mice from indirect calorimetry data
Q51544919Expression of type III hyperlipoproteinemia in apolipoprotein E2 (Arg158 --> Cys) homozygotes is associated with hyperinsulinemia.
Q42175229Fenofibrate increases very low density lipoprotein triglyceride production despite reducing plasma triglyceride levels in APOE*3-Leiden.CETP mice
Q34469947GLP-1 receptor activation inhibits VLDL production and reverses hepatic steatosis by decreasing hepatic lipogenesis in high-fat-fed APOE*3-Leiden mice
Q45171385Generation of a recombinant apolipoprotein E variant with improved biological functions: hydrophobic residues (LEU-261, TRP-264, PHE-265, LEU-268, VAL-269) of apoE can account for the apoE-induced hypertriglyceridemia
Q38519853Genomic analysis of the response of mouse models to high-fat feeding shows a major role of nuclear receptors in the simultaneous regulation of lipid and inflammatory genes
Q37187316Gut-brain axis
Q43990754HOE 402 lowers serum cholesterol levels by reducing VLDL-lipid production, and not by induction of the LDL receptor, and reduces atherosclerosis in wild-type and LDL receptor-deficient mice
Q44739061Hepatic low-density lipoprotein receptor-related protein deficiency in mice increases atherosclerosis independent of plasma cholesterol
Q34776315Hepatocyte-specific IKK-β activation enhances VLDL-triglyceride production in APOE*3-Leiden mice
Q33898304Hepatocyte-specific IKKβ expression aggravates atherosclerosis development in APOE*3-Leiden mice
Q33780322High levels of dietary stearate promote adiposity and deteriorate hepatic insulin sensitivity
Q55162930High levels of whole-body energy expenditure are associated with a lower coupling of skeletal muscle mitochondria in C57Bl/6 mice
Q55162921High-fat diets rich in medium- versus long-chain fatty acids induce distinct patterns of tissue specific insulin resistance
Q46061850Human CETP aggravates atherosclerosis by increasing VLDL-cholesterol rather than by decreasing HDL-cholesterol in APOE*3-Leiden mice
Q37430584Improved cholesterol phenotype analysis by a model relating lipoprotein life cycle processes to particle size
Q44514596Increased hepatic insulin sensitivity together with decreased hepatic triglyceride stores in hormone-sensitive lipase-deficient mice
Q43974040Induction of atherosclerotic plaque rupture in apolipoprotein E-/- mice after adenovirus-mediated transfer of p53.
Q34238637Inhibition of the central melanocortin system decreases brown adipose tissue activity
Q38342071Integrative biological analysis of the APOE*3-leiden transgenic mouse
Q38091828Interactions between inflammation and lipid metabolism: relevance for efficacy of anti-inflammatory drugs in the treatment of atherosclerosis
Q41777277Intracerebroventricular administration of neuropeptide Y induces hepatic insulin resistance via sympathetic innervation
Q45077923Intracerebroventricular neuropeptide Y infusion precludes inhibition of glucose and VLDL production by insulin
Q40189953Intrauterine exposure to maternal atherosclerotic risk factors increases the susceptibility to atherosclerosis in adult life
Q40089428LDL receptor deficiency results in decreased cell proliferation and presynaptic bouton density in the murine hippocampus
Q28732458Lipidomics reveals multiple pathway effects of a multi-components preparation on lipid biochemistry in ApoE*3Leiden.CETP mice
Q46941597Local Cre-mediated gene recombination in vascular smooth muscle cells in mice
Q46425298Local perivascular delivery of anti-restenotic agents from a drug-eluting poly(epsilon-caprolactone) stent cuff
Q47320273Low-density lipoprotein receptor-knockout mice display impaired spatial memory associated with a decreased synaptic density in the hippocampus
Q44816416META060 protects against diet-induced obesity and insulin resistance in a high-fat-diet fed mouse
Q45927694Macrophage p53 controls macrophage death in atherosclerotic lesions of apolipoprotein E deficient mice.
Q24300872Macrophage-specific inhibition of NF-kappaB activation reduces foam-cell formation
Q37209360Maternal transmission of risk for atherosclerosis
Q36149802Metabolomics in the context of systems biology: bridging traditional Chinese medicine and molecular pharmacology
Q44553256Molecular mechanisms of type III hyperlipoproteinemia: The contribution of the carboxy-terminal domain of ApoE can account for the dyslipidemia that is associated with the E2/E2 phenotype
Q46913208Olmesartan and pravastatin additively reduce development of atherosclerosis in APOE*3Leiden transgenic mice
Q44605262Overexpression of APOC1 in obob mice leads to hepatic steatosis and severe hepatic insulin resistance
Q46923076Oxyntomodulin ameliorates glucose intolerance in mice fed a high-fat diet
Q46159072PXR agonism decreases plasma HDL levels in ApoE3-Leiden.CETP mice
Q44995518PYY3-36 reinforces insulin action on glucose disposal in mice fed a high-fat diet
Q42731618Perfluoroalkyl sulfonates cause alkyl chain length-dependent hepatic steatosis and hypolipidemia mainly by impairing lipoprotein production in APOE*3-Leiden CETP mice
Q42797513Peripheral cannabinoid 1 receptor blockade activates brown adipose tissue and diminishes dyslipidemia and obesity
Q53871573Phenotype characterisation using integrated gene transcript, protein and metabolite profiling.
Q27344569Plasma and liver lipidomics response to an intervention of rimonabant in ApoE*3Leiden.CETP transgenic mice
Q46783798Plasma apolipoprotein CI correlates with increased survival in patients with severe sepsis
Q52931087Plasma cholesteryl ester transfer protein is predominantly derived from Kupffer cells.
Q33597037Prenatal exposure to apoE deficiency and postnatal hypercholesterolemia are associated with altered cell-specific lysine methyltransferase and histone methylation patterns in the vasculature
Q36800299Preoperative apolipoprotein CI levels correlate positively with the proinflammatory response in patients experiencing endotoxemia following elective cardiac surgery
Q44064884Raman spectroscopic investigation of atorvastatin, amlodipine, and both on atherosclerotic plaque development in APOE*3 Leiden transgenic mice
Q60233035Rare mutations in the APOE gene associated with dominant mode of inheritance of Familial Dysbetalipoproteinemia (FD)
Q30984423Response of apolipoprotein E*3-Leiden transgenic mice to dietary fatty acids: combining liver proteomics with physiological data
Q46790589Ritonavir impairs lipoprotein lipase-mediated lipolysis and decreases uptake of fatty acids in adipose tissue
Q43199097Ritonavir protects against the development of atherosclerosis in APOE*3-Leiden mice
Q44536746Rosiglitazone improves muscle insulin sensitivity, irrespective of increased triglyceride content, in ob/ob mice
Q44562028Rosuvastatin reduces atherosclerosis development beyond and independent of its plasma cholesterol-lowering effect in APOE*3-Leiden transgenic mice: evidence for antiinflammatory effects of rosuvastatin
Q45197821Rosuvastatin reduces plasma lipids by inhibiting VLDL production and enhancing hepatobiliary lipid excretion in ApoE*3-leiden mice
Q39739995Selective parasympathetic innervation of subcutaneous and intra-abdominal fat--functional implications
Q24319030Severe hypertriglyceridemia in human APOC1 transgenic mice is caused by apoC-I-induced inhibition of LPL
Q45171650Sixteen hours of fasting differentially affects hepatic and muscle insulin sensitivity in mice
Q38315060Specific and efficient targeting of adenovirus vectors to macrophages: application of a fusion protein between an adenovirus-binding fragment and avidin, linked to a biotinylated oligonucleotide
Q40720835Stimulation of lipogenesis by pharmacological activation of the liver X receptor leads to production of large, triglyceride-rich very low density lipoprotein particles
Q35561118Stimulatory effect of insulin on glucose uptake by muscle involves the central nervous system in insulin-sensitive mice
Q37457206Sympathetic nervous system control of triglyceride metabolism: novel concepts derived from recent studies
Q47598134The VLDL receptor plays a major role in chylomicron metabolism by enhancing LPL-mediated triglyceride hydrolysis
Q35058473The effect of PPE-induced emphysema and chronic LPS-induced pulmonary inflammation on atherosclerosis development in APOE*3-LEIDEN mice
Q48497463The effects of high fat diet on the basal activity of the hypothalamus-pituitary-adrenal axis in mice
Q34326186The expression of type III hyperlipoproteinemia: involvement of lipolysis genes
Q30341682The role and mode of action of apolipoproteins CIII and AV: synergistic actors in triglyceride metabolism?
Q47926062The transport of triglycerides through the secretory pathway of hepatocytes is impaired in apolipoprotein E deficient mice
Q46610879Torcetrapib does not reduce atherosclerosis beyond atorvastatin and induces more proinflammatory lesions than atorvastatin
Q46384631Triglyceride-rich lipoprotein metabolism in unique VLDL receptor, LDL receptor, and LRP triple-deficient mice
Q46828709Tumor necrosis factor-alpha plays an important role in restenosis development
Q46380680Tumor necrosis factor-alpha promotes atherosclerotic lesion progression in APOE*3-Leiden transgenic mice
Q43955468VLDL receptor deficiency enhances intimal thickening after vascular injury but does not affect atherosclerotic lesion area
Q47405241Well-characterized garlic-derived materials are not hypolipidemic in APOE*3-Leiden transgenic mice
Q34612131Znf202 affects high density lipoprotein cholesterol levels and promotes hepatosteatosis in hyperlipidemic mice

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