In vitro and ex vivo pharmacodynamics of selected non-steroidal anti-inflammatory drugs in equine whole blood

scientific article published on 11 May 2011

In vitro and ex vivo pharmacodynamics of selected non-steroidal anti-inflammatory drugs in equine whole blood is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/J.TVJL.2011.03.016
P698PubMed publication ID21565533

P50authorRaffaella BarberoQ43168047
Petra CagnardiQ55743581
Giovanni ReQ67819050
P2093author name stringB Cuniberti
P Badino
C Girardi
R Odore
P2860cites workSelectivity of nonsteroidal antiinflammatory drugs as inhibitors of constitutive and inducible cyclooxygenaseQ24563699
Nonsteroid drug selectivities for cyclo-oxygenase-1 rather than cyclo-oxygenase-2 are associated with human gastrointestinal toxicity: a full in vitro analysisQ24646764
Development of in vitro assays for the evaluation of cyclooxygenase inhibitors and predicting selectivity of nonsteroidal anti-inflammatory drugs in catsQ28175675
Human pharmacology of naproxen sodiumQ28222704
Pharmacology of a selective cyclooxygenase-2 inhibitor, HN-56249: a novel compound exhibiting a marked preference for the human enzyme in intact cellsQ28376695
Thromboxanes: a new group of biologically active compounds derived from prostaglandin endoperoxidesQ28619497
Cyclooxygenase-2 expression is induced during human megakaryopoiesis and characterizes newly formed plateletsQ33342580
Dual inhibition of cyclooxygenase-2 (COX-2) and 5-lipoxygenase (5-LOX) as a new strategy to provide safer non-steroidal anti-inflammatory drugsQ35204610
Effects of the novel anti-inflammatory compounds, N-[2-(cyclohexyloxy)-4-nitrophenyl] methanesulphonamide (NS-398) and 5-methanesulphonamido-6-(2,4-difluorothio-phenyl)-1-inda none (L-745,337), on the cyclo-oxygenase activity of human blood prostaglQ35872952
Eltenac, a new anti-inflammatory and analgesic drug for horses: clinical aspectsQ39509027
Critical role of COX-1 in prostacyclin production by human endothelial cells under modification of hydroperoxide toneQ42442777
Correlation between in vitro and in vivo concentration-effect relationships of naproxen in rats and healthy volunteersQ43054314
Effects of the nonsteroidal anti-inflammatory drug naproxen on human erythrocytes and on cell membrane molecular modelsQ43190781
Pharmacokinetic profile and in vitro selective cyclooxygenase-2 inhibition by nimesulide in the dog.Q43604445
Expression and activity of COX-1 and 2 and 5-LOX in joint tissues from dogs with naturally occurring coxofemoral joint osteoarthritisQ43725388
In vitro effects of cyclooxygenase inhibitors in whole blood of horses, dogs, and catsQ43795388
Pharmacodynamics and enantioselective pharmacokinetics of racemic carprofen in the horse.Q44251219
Characterization of eltenac and novel COX-2 selective thiopheneacetic acid analogues in vitro and in vivoQ46449987
COX-1 and COX-2 inhibition in horse blood by phenylbutazone, flunixin, carprofen and meloxicam: an in vitro analysisQ46531185
Oral administration of tepoxalin in the horse: a PK/PD study.Q51387865
Clinical pharmacology and therapeutic uses of non-steroidal anti-inflammatory drugs in the horseQ70087294
Leukotrienes in the pathogenesis of NSAID-induced gastric and intestinal mucosal damageQ72687835
Pharmacology of the 5-lipoxygenase inhibitors BAY Y 1015 and BAY X 1005 in the horseQ73656847
Nonsteroidal anti-inflammatory drugsQ74297732
Inhibition of cyclooxygenase-1 and cyclooxygenase-2 analysis of in vitro test systems and their clinical relevanceQ82944702
Molecular characterization of feline COX-2 and expression in feline mammary carcinomasQ83256672
P433issue3
P921main subjectpharmacodynamicsQ725307
tepoxalinQ7701370
whole bloodQ7997549
P304page(s)327-333
P577publication date2011-05-11
P1433published inThe Veterinary JournalQ15752615
P1476titleIn vitro and ex vivo pharmacodynamics of selected non-steroidal anti-inflammatory drugs in equine whole blood
P478volume191