pralatrexate

chemical compound

DBpedia resource is: http://dbpedia.org/resource/Pralatrexate

Abstract is: Pralatrexate, sold under the brand name Folotyn, is a medication used for the treatment of relapsed or refractory peripheral T-cell lymphoma (PTCL). Pralatrexate was approved for medical use in the United States in September 2009, as the first treatment for Peripheral T-cell Lymphoma (PTCL), an often aggressive type of non-Hodgkins lymphoma.

Wikimedia Commons category is Pralatrexate

C₂₃H₂₃N₇O₅

pralatrexate is …
instance of (P31):
group of stereoisomersQ59199015

sublass of (P279):
unsaturated compoundQ899851

External links are
P267ATC codeL01BA05
P233canonical SMILESC#CCC(CC1=CN=C2C(=N1)C(=NC(=N2)N)N)C3=CC=C(C=C3)C(=O)NC(CCC(=O)O)C(=O)O
P231CAS Registry Number146464-95-1
P683ChEBI ID71223
P592ChEMBL IDCHEMBL1201746
P661ChemSpider ID130578
P715DrugBank IDDB06813
P11198DrugCentral ID4117
P8494DSSTOX compound identifierDTXCID3028504
P3117DSSTox substance IDDTXSID3048578
P232EC number680-662-0
P2566ECHA Substance Infocard ID100.205.791
P646Freebase ID/m/04kkx7n
P595Guide to Pharmacology Ligand ID6840
P2062HSDB ID7786
P234InChIInChI=1S/C23H23N7O5/c1-2-3-14(10-15-11-26-20-18(27-15)19(24)29-23(25)30-20)12-4-6-13(7-5-12)21(33)28-16(22(34)35)8-9-17(31)32/h1,4-7,11,14,16H,3,8-10H2,(H,28,33)(H,31,32)(H,34,35)(H4,24,25,26,29,30)/t14?,16-/m0/s1
P235InChIKeyOGSBUKJUDHAQEA-WMCAAGNKSA-N
P2017isomeric SMILESC#CCC(CC1=CN=C2C(=N1)C(=NC(=N2)N)N)C3=CC=C(C=C3)C(=O)N[C@@H](CCC(=O)O)C(=O)O
P665KEGG IDD05589
P7830LiverTox IDPralatrexate
P10245MedlinePlus drug identifiera610001
P6366Microsoft Academic ID2776209020
P2115NDF-RT IDN0000180303
P2840NSC number754230
P4235PatientsLikeMe treatment IDpralatrexate
P11199Probes And Drugs IDPD004103
P662PubChem CID148121
P1579Reaxys registry number6624234
P3345RxNorm ID662019
P4964SPLASHsplash10-004i-1513900000-5596beb52832aa3566cc
P2877SureChEMBL IDSCHEMBL15075302
SCHEMBL21633
P2892UMLS CUIC1721300
P11089UniChem compound ID104472
P652UNIIA8Q8I19Q20
P11143WikiProjectMed IDPralatrexate

P3780active ingredient inFolotynQ29005877
P366has usemedicationQ12140
P8026LiverTox likelihood scoreLiverTox toxicity likelihood category E*Q83284878
P2067mass477.176067
P2175medical condition treatedmature T-cell and NK-cell lymphomaQ18553445
P129physically interacts withdihydrofolate reductaseQ417149
P9989stylized namePRALAtrexate
P2868subject has roleprotein synthesis inhibitorQ7251505
P2275World Health Organisation international non-proprietary namepralatrexate