Human epidermal growth factor receptor 2 amplification as a biomarker for treatment in patients with lymph node-metastatic penoscrotal extramammary Paget's disease

scientific article published on 14 January 2019

Human epidermal growth factor receptor 2 amplification as a biomarker for treatment in patients with lymph node-metastatic penoscrotal extramammary Paget's disease is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.3892/OL.2019.9930
P932PMC publication ID6365939
P698PubMed publication ID30854041

P50authorYao ZhuQ80682572
P2093author name stringPeipei Zhang
Xiaolin Lu
Dingwei Ye
P2860cites workEvaluation of Dual-Timepoint 18F-FDG PET/CT Imaging for Lymph Node Staging in Vulvar Cancer.Q50621651
Concordance of the HER2 protein and gene status between primary and corresponding lymph node metastatic sites of extramammary Paget disease.Q51707520
Bladder cancer.Q52810295
Successful human epidermal growth receptor 2-targeted therapy beyond disease progression for extramammary Paget's disease.Q53180577
HER2 oncogene amplification in extramammary Paget's disease.Q53861060
Frequent alterations of HER2 through mutation, amplification, or overexpression in pleomorphic lobular carcinoma of the breast.Q54284515
Human epidermal growth factor receptor 2 protein overexpression and gene amplification in extramammary Paget disease.Q54453342
Extramammary Paget disease - clinical appearance, pathogenesis, managementQ56594205
Recommendations for human epidermal growth factor receptor 2 testing in breast cancer: American Society of Clinical Oncology/College of American Pathologists clinical practice guideline updateQ57130157
HER-2/neu expression in Paget disease of the vulva and the female breastQ80878239
Extramammary Paget's disease: analysis of growth signal pathway from the human epidermal growth factor receptor 2 proteinQ81537293
Usefulness of sentinel lymph node biopsy for extramammary Paget diseaseQ83991299
HER-2/neu expression in extramammary Paget disease: a clinicopathologic and immunohistochemistry study of 47 cases with and without underlying malignancyQ84056149
Metastatic extramammary Paget's disease treated with paclitaxel and trastuzumab combination chemotherapyQ84430176
Immunohistochemical and fluorescence in situ hybridization studies on noninvasive and invasive extramammary Paget's diseaseQ87355495
Primary invasive carcinoma associated with penoscrotal extramammary Paget's disease: a clinicopathological analysis of 56 casesQ87679150
Trastuzumab beyond progression in human epidermal growth factor receptor 2-positive advanced breast cancer: a german breast group 26/breast international group 03-05 study.Q27851468
Activating HER2 mutations in HER2 gene amplification negative breast cancerQ27851987
Metastatic Extramammary Paget's Disease of Scrotum Responds Completely to Single Agent Trastuzumab in a Hemodialysis Patient: Case Report, Molecular Profiling and Brief Review of the Literature.Q27853133
p185HER2 overexpression and HER2 oncogene amplification in recurrent vulvar Paget's diseaseQ31098644
A Case of Metastatic Extramammary Paget's Disease Responding to Trastuzumab plus Paclitaxel Combination TherapyQ35563831
Study of neu-protein expression in mammary Paget's disease with and without underlying breast carcinoma and in extramammary Paget's diseaseQ35812141
Extramammary Paget's Disease in Two BrothersQ35944234
Clinical and pathological characteristics of extramammary Paget's disease: report of 246 Chinese male patientsQ36375388
ADAM10-mediated release of heregulin confers resistance to trastuzumab by activating HER3.Q36962935
Human Epidermal Growth Factor Receptor 2 (HER-2/neu)-Directed Therapy for Rare Metastatic Epithelial Tumors with HER-2 AmplificationQ37045824
HER-2/neu targeting for recurrent vulvar Paget's disease A case report and literature reviewQ37077883
An heregulin-EGFR-HER3 autocrine signaling axis can mediate acquired lapatinib resistance in HER2+ breast cancer modelsQ37690880
Extra-mammary Paget's disease of the perianal region: a review of the literature emphasizing the operative management technique.Q37795321
Extramammary Paget disease - clinical appearance, pathogenesis, managementQ37825971
H1047R phosphatidylinositol 3-kinase mutant enhances HER2-mediated transformation by heregulin production and activation of HER3Q39687743
Usefulness of docetaxel as first-line chemotherapy for metastatic extramammary Paget's disease.Q40279396
HER2 gene copy number and breast cancer-specific survivalQ40714642
Dramatic Clinical Response of Relapsed Metastatic Extramammary Paget's Disease to Trastuzumab MonotherapyQ41809775
Clinicopathological characteristics, management and outcome of metastatic penoscrotal extramammary Paget's diseaseQ42170233
Immunohistochemical study of HER2 and TUBB3 proteins in extramammary Paget diseaseQ43036839
Bladder cancer: epidemiology, staging and grading, and diagnosis.Q45247416
Variable patterns of positron emission tomography in the assessment of patients with extramammary Paget's diseaseQ45251646
HER-2/NEU overexpression in vulvar Paget disease: the Yale experience.Q45928424
F-18 FDG PET/CT imaging of extramammary Paget disease of the perianal regionQ46771121
Evaluation of positron emission tomography imaging to detect lymph node metastases in patients with extramammary Paget's diseaseQ48125018
Sentinel lymph node biopsy in patients with extramammary Paget's disease.Q50488004
P433issue3
P407language of work or nameEnglishQ1860
P921main subjectextramammary Paget's diseaseQ3077016
targeted therapyQ492646
biomarkerQ864574
P304page(s)2677-2686
P577publication date2019-01-14
P1433published inOncology LettersQ20640514
P1476titleHuman epidermal growth factor receptor 2 amplification as a biomarker for treatment in patients with lymph node-metastatic penoscrotal extramammary Paget's disease
P478volume17