| review article | Q7318358 |
| scholarly article | Q13442814 |
| P50 | author | Zhenhan Deng | Q90457626 |
| P2093 | author name string | Chao Cheng | |
| Jian Tian | |||
| Haifeng Liu | |||
| Liangjun Li | |||
| Yusheng Li | |||
| Fangjie Zhang | |||
| Greg Zhang | |||
| Shengshi Xiao | |||
| P2860 | cites work | The effect of lentivirus-mediated SIRT1 gene knockdown in the ATDC5 cell line via inhibition of the Wnt signaling pathway | Q91855931 |
| Silent information regulator 2 family of NAD- dependent histone/protein deacetylases generates a unique product, 1-O-acetyl-ADP-ribose | Q24675630 | ||
| Redox regulation of SIRT1 in inflammation and cellular senescence | Q27023972 | ||
| Mechanism of human SIRT1 activation by resveratrol | Q28238262 | ||
| Sirtuin activators | Q28244893 | ||
| Substrate-specific activation of sirtuins by resveratrol | Q28305166 | ||
| Resveratrol inhibits interleukin 1β-mediated inducible nitric oxide synthase expression in articular chondrocytes by activating SIRT1 and thereby suppressing nuclear factor-κB activity | Q28583282 | ||
| Sirtuins in mammals: insights into their biological function | Q29615248 | ||
| Ionizing radiation induces cellular senescence of articular chondrocytes via negative regulation of SIRT1 by p38 kinase | Q33569707 | ||
| The secret life of NAD+: an old metabolite controlling new metabolic signaling pathways | Q33779682 | ||
| DOT1L safeguards cartilage homeostasis and protects against osteoarthritis. | Q33827165 | ||
| Beneficial effect of resveratrol on phenotypic features and activity of osteoarthritic osteoblasts. | Q33859078 | ||
| Sirtuin 1 enzymatic activity is required for cartilage homeostasis in vivo in a mouse model | Q33893466 | ||
| NAD+ and sirtuins in aging and disease | Q33955066 | ||
| Sirtuin-1 (SIRT1) is required for promoting chondrogenic differentiation of mesenchymal stem cells | Q34070378 | ||
| SirT1 enhances survival of human osteoarthritic chondrocytes by repressing protein tyrosine phosphatase 1B and activating the insulin-like growth factor receptor pathway. | Q34072652 | ||
| The Role of SIRT1 in Diabetic Kidney Disease. | Q34312543 | ||
| Sirt1-deficient mice exhibit an altered cartilage phenotype | Q34889561 | ||
| Low sirtuin 1 levels in human osteoarthritis subchondral osteoblasts lead to abnormal sclerostin expression which decreases Wnt/β-catenin activity | Q35030853 | ||
| Oxidative stress induces imbalance of adipogenic/osteoblastic lineage commitment in mesenchymal stem cells through decreasing SIRT1 functions | Q41991392 | ||
| Mitochondrial biogenesis is impaired in osteoarthritis chondrocytes but reversible via peroxisome proliferator-activated receptor γ coactivator 1α | Q42176724 | ||
| Evolution of pain at 3 months by oral resveratrol in knee osteoarthritis (ARTHROL): protocol for a multicentre randomised double-blind placebo-controlled trial | Q42376847 | ||
| Clock Gene Bmal1 Modulates Human Cartilage Gene Expression by Crosstalk With Sirt1. | Q42392472 | ||
| Resveratrol, a sirtuin 1 activator, increases IL-6 production by peripheral blood mononuclear cells of patients with knee osteoarthritis | Q43084482 | ||
| SIRT1 regulation of apoptosis of human chondrocytes | Q43284360 | ||
| Sirt1 regulates apoptosis and extracellular matrix degradation in resveratrol-treated osteoarthritis chondrocytes via the Wnt/β-catenin signaling pathways | Q47110183 | ||
| Set7/9 impacts COL2A1 expression through binding and repression of SirT1 histone deacetylation | Q47965829 | ||
| Spontaneous up-regulation of SIRT1 during osteogenesis contributes to stem cells' resistance to oxidative stress. | Q48520056 | ||
| Inhibition of microRNA-449a prevents IL-1β-induced cartilage destruction via SIRT1. | Q48621689 | ||
| Disruption of Sirt1 in chondrocytes causes accelerated progression of osteoarthritis under mechanical stress and during ageing in mice. | Q50948674 | ||
| Underlying mechanism of Sirt1 on apoptosis and extracellular matrix degradation of osteoarthritis chondrocytes. | Q50957507 | ||
| Fisetin inhibits IL-1β-induced inflammatory response in human osteoarthritis chondrocytes through activating SIRT1 and attenuates the progression of osteoarthritis in mice. | Q51132846 | ||
| Nutrient availability regulates SIRT1 through a forkhead-dependent pathway. | Q51565792 | ||
| Bone morphogenetic proteins for articular cartilage regeneration. | Q51759267 | ||
| Rutin protects rat articular chondrocytes against oxidative stress induced by hydrogen peroxide through SIRT1 activation. | Q53120430 | ||
| Vav1 Regulates Mesenchymal Stem Cell Differentiation Decision Between Adipocyte and Chondrocyte via Sirt1. | Q53144361 | ||
| Oxidative stress induces senescence in chondrocytes. | Q53270994 | ||
| Defects in mesenchymal stem cell self-renewal and cell fate determination lead to an osteopenic phenotype in Bmi-1 null mice. | Q54470756 | ||
| Quercetin attenuates mitochondrial dysfunction and biogenesis via upregulated AMPK/SIRT1 signaling pathway in OA rats. | Q54977155 | ||
| Intraperitoneal injection of the SIRT1 activator SRT1720 attenuates the progression of experimental osteoarthritis in mice. | Q55480930 | ||
| Osteocytic oxygen sensing controls bone mass through epigenetic regulation of sclerostin. | Q55517542 | ||
| Hydroxytyrosol modulates the levels of microRNA-9 and its target sirtuin-1 thereby counteracting oxidative stress-induced chondrocyte death | Q56960745 | ||
| Inhibition of miR-449a Promotes Cartilage Regeneration and Prevents Progression of Osteoarthritis in In Vivo Rat Models | Q57491156 | ||
| Efficacy and safety of co-administration of resveratrol with meloxicam in patients with knee osteoarthritis: a pilot interventional study | Q58763044 | ||
| Management of osteoarthritis of the knee | Q61649681 | ||
| Sirt1 Promotes a Thermogenic Gene Program in Bone Marrow Adipocytes: From Mice to (Wo)Men | Q64087501 | ||
| The effect of O2 tension on pH homeostasis in equine articular chondrocytes | Q79318169 | ||
| Potential involvement of SIRT1 in the pathogenesis of osteoarthritis through the modulation of chondrocyte gene expressions | Q83452293 | ||
| SIRT1 overexpression in the rheumatoid arthritis synovium contributes to proinflammatory cytokine production and apoptosis resistance | Q84531194 | ||
| The overexpression of SIRT1 inhibited osteoarthritic gene expression changes induced by interleukin-1β in human chondrocytes | Q85411133 | ||
| Silent information regulator (Sir)T1 inhibits NF-κB signaling to maintain normal skeletal remodeling | Q85505080 | ||
| Aging impairs beige adipocyte differentiation of mesenchymal stem cells via the reduced expression of Sirtuin 1 | Q88425381 | ||
| Update on the epidemiology, risk factors and disease outcomes of osteoarthritis | Q90346749 | ||
| Mechanical stretch induces antioxidant responses and osteogenic differentiation in human mesenchymal stem cells through activation of the AMPK-SIRT1 signaling pathway | Q90872773 | ||
| Resveratrol Supplementation Reduces Pain and Inflammation in Knee Osteoarthritis Patients Treated with Meloxicam: A Randomized Placebo-Controlled Study | Q91220669 | ||
| Sirt1 Promotes Osteogenic Differentiation and Increases Alveolar Bone Mass via Bmi1 Activation in Mice | Q91253361 | ||
| Nicotinamide phosphoribosyltransferase is essential for interleukin-1beta-mediated dedifferentiation of articular chondrocytes via SIRT1 and extracellular signal-regulated kinase (ERK) complex signaling | Q35150292 | ||
| Tumor necrosis factor α-mediated cleavage and inactivation of SirT1 in human osteoarthritic chondrocytes | Q35215468 | ||
| Expression profiling of metalloproteinases and their inhibitors in synovium and cartilage | Q35605620 | ||
| 75-kd sirtuin 1 blocks tumor necrosis factor α-mediated apoptosis in human osteoarthritic chondrocytes | Q35718396 | ||
| Hydroxytyrosol prevents chondrocyte death under oxidative stress by inducing autophagy through sirtuin 1-dependent and -independent mechanisms. | Q35946979 | ||
| SIRT1 inhibits adipogenesis and promotes myogenic differentiation in C3H10T1/2 pluripotent cells by regulating Wnt signaling | Q36276243 | ||
| Increased apoptotic chondrocytes in articular cartilage from adult heterozygous SirT1 mice. | Q36390894 | ||
| SIRT1 and energy metabolism | Q36479802 | ||
| SIRT1 regulates differentiation of mesenchymal stem cells by deacetylating β-catenin. | Q36685949 | ||
| Sirtuins, Cell Senescence, and Vascular Aging | Q36844727 | ||
| Acetylation reduces SOX9 nuclear entry and ACAN gene transactivation in human chondrocytes. | Q36863764 | ||
| MicroRNA-34a affects chondrocyte apoptosis and proliferation by targeting the SIRT1/p53 signaling pathway during the pathogenesis of osteoarthritis | Q36983759 | ||
| Regulation of cartilage-specific gene expression in human chondrocytes by SirT1 and nicotinamide phosphoribosyltransferase. | Q37021544 | ||
| The NAD-Dependent Deacetylase Sirtuin-1 Regulates the Expression of Osteogenic Transcriptional Activator Runt-Related Transcription Factor 2 (Runx2) and Production of Matrix Metalloproteinase (MMP)-13 in Chondrocytes in Osteoarthritis | Q37134372 | ||
| Aging and osteoarthritis: the role of chondrocyte senescence and aging changes in the cartilage matrix | Q37268683 | ||
| Cartilage homeostasis in health and rheumatic diseases | Q37270714 | ||
| The expression of SIRT1 in articular cartilage of patients with knee osteoarthritis and its correlation with disease severity | Q37423992 | ||
| SIRT1 suppresses adipogenesis by activating Wnt/β-catenin signaling in vivo and in vitro | Q37718426 | ||
| T Cells in Osteoarthritis: Alterations and Beyond | Q37727495 | ||
| Role of proinflammatory cytokines in the pathophysiology of osteoarthritis | Q37814044 | ||
| Franklin H. Epstein Lecture: Sirtuins, aging, and medicine | Q37886170 | ||
| Role of sirtuins, calorie restriction and physical activity in aging | Q37971653 | ||
| Epigenetics, sirtuins and osteoarthritis | Q38022093 | ||
| Seven sirtuins for seven deadly diseases of aging | Q38056043 | ||
| Role of HIF-1α and HIF-2α in osteoarthritis | Q38305626 | ||
| The effect of resveratrol on normal and osteoarthritic chondrocyte metabolism | Q38427475 | ||
| SIRT1, a class III histone deacetylase, regulates TNF-α-induced inflammation in human chondrocytes. | Q38455313 | ||
| Autophagy in osteoarthritis | Q38603339 | ||
| Epigenetics of cartilage diseases | Q38684974 | ||
| Effect of glucosamine on expression of type II collagen, matrix metalloproteinase and sirtuin genes in a human chondrocyte cell line | Q38723742 | ||
| SOX9 and the many facets of its regulation in the chondrocyte lineage | Q38820782 | ||
| Cellular aging towards osteoarthritis | Q39065937 | ||
| LEF1-mediated MMP13 gene expression is repressed by SIRT1 in human chondrocytes | Q39227561 | ||
| Cytoprotective and anti-inflammatory effects of melatonin in hydrogen peroxide-stimulated CHON-001 human chondrocyte cell line and rabbit model of osteoarthritis via the SIRT1 pathway | Q39364017 | ||
| Reduced Sirtuin1 expression at the femoral neck in women who sustained an osteoporotic hip fracture | Q40354556 | ||
| P275 | copyright license | Creative Commons Attribution | Q6905323 |
| P6216 | copyright status | copyrighted | Q50423863 |
| P433 | issue | 5 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | antioxidant | Q133948 |
| biophysics | Q7100 | ||
| resveratrol | Q407329 | ||
| cartilage | Q502730 | ||
| osteoarthritis | Q62736 | ||
| chondrocyte | Q775480 | ||
| P304 | page(s) | BSR20190189 | |
| P577 | publication date | 2019-05-10 | |
| 2019-05-31 | |||
| P1433 | published in | Bioscience Reports | Q2790714 |
| P1476 | title | The role of sirtuin 1 and its activator, resveratrol in osteoarthritis | |
| P478 | volume | 39 |
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