Relationship between Clozapine-Induced Electroencephalogram Abnormalities and Serum Concentration of Clozapine in Japanese Patients with Treatment-Resistant Schizophrenia

Relationship between Clozapine-Induced Electroencephalogram Abnormalities and Serum Concentration of Clozapine in Japanese Patients with Treatment-Resistant Schizophrenia is …
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scholarly articleQ13442814

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P356DOI10.30773/PI.2018.12.16
P932PMC publication ID6504775
P698PubMed publication ID30947495

P50authorTakashi KanbayashiQ89617945
P2093author name stringTetsuo Shimizu
Yuka Sugawara Kikuchi
P2860cites workTherapeutic drug monitoring of clozapine and relapse--a retrospective study of routine clinical data.Q30765869
Influence of dose, cigarette smoking, age, sex, and metabolic activity on plasma clozapine concentrations: a predictive model and nomograms to aid clozapine dose adjustment and to assess compliance in individual patientsQ34288360
Pharmacokinetics of clozapine and its metabolites in psychiatric patients: plasma protein binding and renal clearanceQ35802661
Gender, age, smoking behaviour and plasma clozapine concentrations in 193 Chinese inpatients with schizophreniaQ36024542
Effect of caffeine on clozapine pharmacokinetics in healthy volunteersQ36055008
Population pharmacokinetics of clozapine evaluated with the nonparametric maximum likelihood methodQ36094183
Sex differences in plasma clozapine and norclozapine concentrations in clinical practice and in relation to body mass index and plasma glucose concentrations: a retrospective surveyQ36294225
Electroencephalographic abnormalities in clozapine-treated patients: a cross-sectional studyQ39995056
The usefulness of monitored therapy using Clozapine concentration in the blood serum for determining drug dose in Polish schizophrenic patients.Q40597170
Efficacy and adverse effects of clozapine in the treatment of schizophrenia and tardive dyskinesia--a retrospective study of 387 patientsQ40779000
Prediction of working memory performance in schizophrenia by plasma ratio of clozapine to N-desmethylclozapineQ41093298
Clozapine-induced seizures and EEG changesQ42282305
EEG alterations and seizures during treatment with clozapine. A retrospective study of 283 patientsQ42289198
Clozapine-induced electroencephalogram changes as a function of clozapine serum levelsQ42548854
Determination of clozapine and its N-demethylated metabolite in plasma by use of gas chromatography-mass spectrometry with single ion detectionQ43794493
EEG abnormalities during treatment with typical and atypical antipsychoticsQ43843047
Tobacco and cannabis smoking cessation can lead to intoxication with clozapine or olanzapineQ43974558
Clozapine, norclozapine plasma levels, their sum and ratio in 50 psychotic patients: influence of patient-related variablesQ43986056
Increasing the clozapine: norclozapine ratio with co-administration of fluvoxamine to enhance efficacy and minimize side effects of clozapine therapyQ44594935
An inter-ethnic comparison study of clozapine dosage, clinical response and plasma levelsQ46423766
Estimating the size of the effects of co-medications on plasma clozapine concentrations using a model that controls for clozapine doses and confounding variables.Q46592286
Plasma ratio of clozapine to N-desmethylclozapine can predict cognitive performance in treatment-resistant psychotic patientsQ47599108
Effects of caffeine withdrawal from the diet on the metabolism of clozapine in schizophrenic patientsQ47740544
Steady-State Clozapine and Norclozapine Pharmacokinetics in Maori and European PatientsQ49646975
Relationship between patient variables and plasma clozapine concentrations: a dosing nomogram.Q50859607
Clozapine dosage, serum levels, efficacy, and side-effect profiles: a comparison of Korean-American and Caucasian patients.Q51012886
Influence of patient-related variables on clozapine plasma levels.Q52055220
Dose-related plasma levels of clozapine: influence of smoking behaviour, sex and ageQ69795312
EEG alterations in patients treated with clozapine in relation to plasma levelsQ72521614
Long-term therapeutic drug monitoring of clozapine and metabolites in psychiatric in- and outpatientsQ73101138
Clozapine serum concentrations are lower in smoking than in non-smoking schizophrenic patientsQ73296823
Clozapine dosages and plasma drug concentrationsQ73681688
Pharmacokinetic interactions of clozapine with selective serotonin reuptake inhibitors: differential effects of fluvoxamine and paroxetine in a prospective studyQ74212194
Clinical predictors of serum clozapine levels in patients with treatment-resistant schizophreniaQ85299028
P275copyright licenseCreative Commons Attribution-NonCommercial 4.0 InternationalQ34179348
P6216copyright statuscopyrightedQ50423863
P433issue4
P407language of work or nameEnglishQ1860
P921main subjectschizophreniaQ41112
Treatment-resistant schizophreniaQ60491684
serum concentrationQ126107668
P304page(s)279-284
P577publication date2018-04-01
P1433published inPsychiatry investigationQ26853796
P1476titleRelationship between Clozapine-Induced Electroencephalogram Abnormalities and Serum Concentration of Clozapine in Japanese Patients with Treatment-Resistant Schizophrenia
P478volume16

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