Revisiting the Brain Renin-Angiotensin System-Focus on Novel Therapies

Revisiting the Brain Renin-Angiotensin System-Focus on Novel Therapies is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

External links are
P6179Dimensions Publication ID1113185280
P356DOI10.1007/S11906-019-0937-8
P932PMC publication ID6449495
P698PubMed publication ID30949864

P2093author name stringA H Jan Danser
Xifeng Lu
Liwei Ren
P2860cites workProtective effects of the angiotensin II AT2 receptor agonist compound 21 in ischemic stroke: a nose-to-brain delivery approach.Q51745079
Renin- and prorenin-induced effects in rat vascular smooth muscle cells overexpressing the human (pro)renin receptor: does (pro)renin-(pro)renin receptor interaction actually occur?Q53210609
Studies on angiotensinogen of plasma and cerebrospinal fluid in normal and hypertensive human subjectsQ71267920
Effects of angiotensin II and its metabolites in the rat coronary vascular bed: is angiotensin III the preferred ligand of the angiotensin AT2 receptor?Q81356302
Multiple ascending dose study with the new renin inhibitor VTP-27999: nephrocentric consequences of too much renin inhibitionQ87177658
The angiotensin type 2 receptor agonist Compound 21 elicits cerebroprotection in endothelin-1 induced ischemic strokeQ87255898
Direct stimulation of angiotensin II type 2 receptor initiated after stroke ameliorates ischemic brain damageQ87364788
Angiotensin (1-7) does not interact directly with MAS1, but can potently antagonize signaling from the AT1 receptorQ89179165
Brain renin-angiotensin system blockade with orally active aminopeptidase A inhibitor prevents cardiac dysfunction after myocardial infarction in miceQ90836305
Selective Deletion of the Brain-Specific Isoform of Renin Causes Neurogenic HypertensionQ30275701
Intrarenal angiotensin III infusion induces natriuresis and angiotensin type 2 receptor translocation in Wistar-Kyoto but not in spontaneously hypertensive ratsQ30437186
Possible inhibition of focal cerebral ischemia by angiotensin II type 2 receptor stimulationQ33205413
Circulating angiotensin II gains access to the hypothalamus and brain stem during hypertension via breakdown of the blood-brain barrierQ33842137
Cardiac phenotype and angiotensin II levels in AT1a, AT1b, and AT2 receptor single, double, and triple knockoutsQ33844005
Renal responses to three types of renin-angiotensin system blockers in patients with diabetes mellitus on a high-salt diet: a need for higher doses in diabetic patients?Q34453476
Activation of the Neuroprotective Angiotensin-Converting Enzyme 2 in Rat Ischemic StrokeQ35738095
A Salt-Induced Reno-Cerebral Reflex Activates Renin-Angiotensin Systems and Promotes CKD ProgressionQ35790573
Liver angiotensinogen is the primary source of renal angiotensin II.Q36050931
Lack of specificity of commercial antibodies leads to misidentification of angiotensin type 1 receptor proteinQ36470843
Aminopeptidase A inhibitors as potential central antihypertensive agentsQ36675846
Intracerebroventricular infusion of the (Pro)renin receptor antagonist PRO20 attenuates deoxycorticosterone acetate-salt-induced hypertensionQ36992645
Circulating versus tissue renin-angiotensin system: on the origin of (pro)reninQ37161448
Angiotensin receptor blockers should be regarded as first-line drugs for stroke prevention in both primary and secondary prevention settings: yes.Q37567195
Neuron-specific (pro)renin receptor knockout prevents the development of salt-sensitive hypertensionQ37626138
Angiotensin-converting enzyme 2-independent action of presumed angiotensin-converting enzyme 2 activators: studies in vivo, ex vivo, and in vitroQ37731227
The Role of the (Pro)renin Receptor in Hypertensive DiseaseQ38428278
Compromised blood-brain barrier permeability: novel mechanism by which circulating angiotensin II signals to sympathoexcitatory centres during hypertensionQ38637276
Reno-Cerebral Reflex Activates the Renin-Angiotensin System, Promoting Oxidative Stress and Renal Damage After Ischemia-Reperfusion InjuryQ39057673
(Pro)renin receptor as a therapeutic target for the treatment of cardiovascular diseases?Q39191078
Mineralocorticoid and angiotensin II type 1 receptors in the subfornical organ mediate angiotensin II - induced hypothalamic reactive oxygen species and hypertensionQ40762004
Distinct renin isoforms generated by tissue-specific transcription initiation and alternative splicingQ40975383
AT2 receptor-mediated vasodilation in the mouse heart depends on AT1A receptor activationQ41819451
The (pro)renin receptor/ATP6AP2 is essential for vacuolar H+-ATPase assembly in murine cardiomyocytes.Q41935568
Compound 21 induces vasorelaxation via an endothelium- and angiotensin II type 2 receptor-independent mechanismQ42716918
Renal Atp6ap2/(Pro)renin Receptor Is Required for Normal Vacuolar H+-ATPase Function but Not for the Renin-Angiotensin System.Q42722913
Beneficial cardiac effects of the renin inhibitor aliskiren in spontaneously hypertensive ratsQ42972308
Subcellular localization of angiotensin II in kidney and adrenalQ43591393
Podocyte injury enhances filtration of liver-derived angiotensinogen and renal angiotensin II generationQ44488209
(Pro)renin Receptor Inhibition Reprograms Hepatic Lipid Metabolism and Protects Mice from Diet-Induced Obesity and Hepatosteatosis.Q47231495
Central and Peripheral Slow-Pressor Mechanisms Contributing to.Q47416221
Angiotensin II Type 2 Receptor and Receptor Mas Are Colocalized and Functionally Interdependent in Obese Zucker Rat KidneyQ47924559
Central antihypertensive effects of chronic treatment with RB150: an orally active aminopeptidase A inhibitor in deoxycorticosterone acetate-salt rats.Q48088455
Immunocytochemical localization of angiotensinogen in the rat brainQ48089905
Central pressor actions of aminopeptidase-resistant angiotensin II analogs: challenging the angiotensin III hypothesisQ48182833
The brain renin-angiotensin system contributes to the hypertension in mice containing both the human renin and human angiotensinogen transgenesQ48350561
Astrocytes Contribute to Angiotensin II Stimulation of Hypothalamic Neuronal Activity and Sympathetic OutflowQ48489132
Angiotensin-forming enzyme in brain tissueQ48805828
Adipocytes do not significantly contribute to plasma angiotensinogen.Q49793034
Brain Renin-Angiotensin System: Does It Exist?Q51064303
Identification of the (Pro)renin Receptor as a Novel Regulator of Low-Density Lipoprotein Metabolism.Q51740281
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P433issue4
P407language of work or nameEnglishQ1860
P921main subjectbrainQ1073
sympathetic nervous systemQ187215
brain renin-angiotensin systemQ15311907
P304page(s)28
P577publication date2019-04-04
P1433published inCurrent Hypertension ReportsQ15746362
P1476titleRevisiting the Brain Renin-Angiotensin System-Focus on Novel Therapies
P478volume21

Reverse relations

cites work (P2860)
Q94571148COVID-19, Angiotensin Receptor Blockers, and the Brain
Q98775878Intrinsic disorder perspective of an interplay between the renin-angiotensin-aldosterone system and SARS-CoV-2
Q92566054The Renin-Angiotensin System in the Central Nervous System and Its Role in Blood Pressure Regulation

Search more.