MERTK mediated novel site Akt phosphorylation alleviates SAV1 suppression

scientific article published on 03 April 2019

MERTK mediated novel site Akt phosphorylation alleviates SAV1 suppression is …
instance of (P31):
scholarly articleQ13442814

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P819ADS bibcode2019NatCo..10.1515J
P6179Dimensions Publication ID1113182115
P356DOI10.1038/S41467-019-09233-7
P932PMC publication ID6447540
P698PubMed publication ID30944303

P50authorAlisha HoltzhausenQ91409265
Yanqiong ZhangQ92828990
Nikolay V. DokholyanQ38319632
Charles M. PerouQ30503513
P2093author name stringIan Davis
Yang Xiang
Cheng Fan
Gang Wu
Pengda Liu
Xiaodong Wang
Yao Jiang
H Shelton Earp
William Y Kim
Siyuan Su
Konstantin I Popov
Jiayi Qian
Janet Y Leung
Eric Ubil
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salvador Promotes both cell cycle exit and apoptosis in Drosophila and is mutated in human cancer cell linesQ28219379
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MERTK receptor tyrosine kinase is a therapeutic target in melanoma.Q30539324
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AKT plays a central role in tumorigenesisQ33944165
Downregulation of SAV1 plays a role in pathogenesis of high-grade clear cell renal cell carcinomaQ34106752
Overexpression of MERTK receptor tyrosine kinase in epithelial cancer cells drives efferocytosis in a gain-of-function capacityQ34170756
Direct regulation of GAS6/AXL signaling by HIF promotes renal metastasis through SRC and MET.Q34217927
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Akt-mediated phosphorylation of XLF impairs non-homologous end-joining DNA repairQ35108163
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PtdIns(3,4,5)P3-Dependent Activation of the mTORC2 Kinase Complex.Q36244792
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Perturbations of the AKT signaling pathway in human cancerQ36313181
Ab initio folding of proteins with all-atom discrete molecular dynamicsQ36870976
How good is automated protein docking?Q37601847
pVHL suppresses kinase activity of Akt in a proline-hydroxylation-dependent mannerQ37666827
WW domain interactions regulate the Hippo tumor suppressor pathwayQ37890248
The regulation of cell sizeQ38137331
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue1
P407language of work or nameEnglishQ1860
P921main subjectphosphorylationQ242736
P304page(s)1515
P577publication date2019-04-03
P1433published inNature CommunicationsQ573880
P1476titleMERTK mediated novel site Akt phosphorylation alleviates SAV1 suppression
P478volume10

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cites work (P2860)
Q92842588Beyond growth signaling: apoptotic sensor MERTK activates AKT by a novel mechanism
Q95320552Correction of the tumor suppressor Salvador homolog-1 deficiency in tumors by lycorine as a new strategy in lung cancer therapy

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