A comprehensive characterisation of large-scale expanded human bone marrow and umbilical cord mesenchymal stem cells

A comprehensive characterisation of large-scale expanded human bone marrow and umbilical cord mesenchymal stem cells is …
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scholarly articleQ13442814

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P6179Dimensions Publication ID1112854717
P356DOI10.1186/S13287-019-1202-4
P932PMC publication ID6421680
P698PubMed publication ID30885254

P2093author name stringJohn Garcia
Sally Roberts
Charlotte Hulme
Karina Wright
Claire Mennan
P2860cites workExploring the full spectrum of macrophage activationQ24653754
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Interferon-gamma does not break, but promotes the immunosuppressive capacity of adult human mesenchymal stem cellsQ24681395
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Human MSC suppression correlates with cytokine induction of indoleamine 2,3-dioxygenase and bystander M2 macrophage differentiationQ84968409
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Evaluation of a cell-banking strategy for the production of clinical grade mesenchymal stromal cells from Wharton's jelly.Q50914748
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Autologous bone marrow stromal cell transplantation for repair of full-thickness articular cartilage defects in human patellae: two case reports.Q51575936
High passage number of stem cells adversely affects stem cell activation and myocardial protection.Q51776060
Injectable cultured bone marrow-derived mesenchymal stem cells in varus knees with cartilage defects undergoing high tibial osteotomy: a prospective, randomized controlled clinical trial with 2 years' follow-up.Q53099155
Heterotopic of bone marrow. Analysis of precursor cells for osteogenic and hematopoietic tissuesQ53745526
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GMP Production and Scale-Up of Adherent Neural Stem Cells with a Quantum Cell Expansion System.Q55515982
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Differential distribution of B7.1 (CD80) and B7.2 (CD86) costimulatory molecules on mucosal macrophage subsets in human inflammatory bowel disease (IBD)Q73836005
Immunogenicity and immunomodulatory properties of umbilical cord lining mesenchymal stem cellsQ82335420
The problem is obvious, the solution is not: numbers do matter in cardiac cell therapy!Q84918254
Multilineage potential of adult human mesenchymal stem cellsQ27860737
Minimal criteria for defining multipotent mesenchymal stromal cells. The International Society for Cellular Therapy position statementQ27861120
Influence of the mannose receptor in host immune responsesQ28307450
The alpha(1)beta(1) and alpha(2)beta(1) integrins provide critical support for vascular endothelial growth factor signaling, endothelial cell migration, and tumor angiogenesisQ28344804
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Aging of mesenchymal stem cell in vitro.Q33236089
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Joint morphogenetic cells in the adult mammalian synoviumQ33860659
Efficient manufacturing of therapeutic mesenchymal stromal cells with the use of the Quantum Cell Expansion System.Q33864713
Genetic stability of bone marrow-derived human mesenchymal stromal cells in the Quantum SystemQ33977993
Are serum-free and xeno-free culture conditions ideal for large scale clinical grade expansion of Wharton's jelly derived mesenchymal stem cells? A comparative studyQ34586865
Immune modulation to improve tissue engineering outcomes for cartilage repair in the osteoarthritic jointQ35064664
Integrin alpha1beta1 mediates a unique collagen-dependent proliferation pathway in vivoQ36256242
The macrophage scavenger receptor CD163.Q36257860
Characterisation of synovial fluid and infrapatellar fat pad derived mesenchymal stromal cells: The influence of tissue source and inflammatory stimulus.Q36793110
A double blind randomized placebo controlled phase I/II study assessing the safety and efficacy of allogeneic bone marrow derived mesenchymal stem cell in critical limb ischemiaQ36944312
Isolation and characterisation of mesenchymal stem cells from different regions of the human umbilical cordQ37091078
Intra-articular injection of two different doses of autologous bone marrow mesenchymal stem cells versus hyaluronic acid in the treatment of knee osteoarthritis: multicenter randomized controlled clinical trial (phase I/II).Q37211983
Mesenchymal stromal cells derived from whole human umbilical cord exhibit similar properties to those derived from Wharton's jelly and bone marrowQ37393107
Efficacy of umbilical cord-derived mesenchymal stem cell-based therapy for osteonecrosis of the femoral head: A three-year follow-up studyQ37403407
Culture expansion of adipose derived stromal cells. A closed automated Quantum Cell Expansion System compared with manual flask-based culture.Q37419366
Stromal cells from the adipose tissue-derived stromal vascular fraction and culture expanded adipose tissue-derived stromal/stem cells: a joint statement of the International Federation for Adipose Therapeutics and Science (IFATS) and the InternatioQ37691742
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A randomised double-blind, placebo-controlled trial of allogeneic umbilical cord-derived mesenchymal stem cell for lupus nephritisQ39191234
Treatment of Knee Osteoarthritis With Allogeneic Bone Marrow Mesenchymal Stem Cells: A Randomized Controlled TrialQ39191801
MSCs: Delivery Routes and Engraftment, Cell-Targeting Strategies, and Immune ModulationQ39356606
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Diminished callus size and cartilage synthesis in alpha 1 beta 1 integrin-deficient mice during bone fracture healingQ42048066
Osteogenic differentiation of purified, culture-expanded human mesenchymal stem cells in vitroQ42529073
Immunological characterization of multipotent mesenchymal stromal cells--The International Society for Cellular Therapy (ISCT) working proposalQ42595918
Modulation of integrin expression on rat bone marrow cells by substrates with different surface characteristicsQ44118801
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Species variation in the mechanisms of mesenchymal stem cell-mediated immunosuppression.Q45959326
Intra-articular injection of expanded autologous bone marrow mesenchymal cells in moderate and severe knee osteoarthritis is safe: a phase I/II study.Q46347205
Role for interferon-gamma in the immunomodulatory activity of human bone marrow mesenchymal stem cells.Q46670167
Indoleamine 2,3 dioxygenase and human leucocyte antigen-G inhibit the T-cell alloproliferative response through two independent pathwaysQ46762912
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P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue1
P407language of work or nameEnglishQ1860
P921main subjectbelly cordQ172563
human umbilical cord mesenchymal stem cellQ107296600
telomere lengthQ59658244
P304page(s)99
P577publication date2019-03-18
P1433published inStem Cell Research & TherapyQ14390536
P1476titleA comprehensive characterisation of large-scale expanded human bone marrow and umbilical cord mesenchymal stem cells
P478volume10

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cites work (P2860)
Q104142348Challenges and translational considerations of mesenchymal stem/stromal cell therapy for Parkinson's disease
Q101476239Effect and mechanism of human umbilical cord mesenchymal stem cells in treating allergic rhinitis in mice
Q96766464Injected human umbilical cord-derived mesenchymal stromal cells do not appear to elicit an inflammatory response in a murine model of osteoarthritis
Q90748221Mesenchymal Stem Cell-Derived Extracellular Vesicles: Challenges in Clinical Applications
Q99579307Off-the-shelf mesenchymal stem cells from human umbilical cord tissue can significantly improve symptoms in COVID-19 patients: An analysis of evidential relations
Q91815545Polysaccharide-Based Systems for Targeted Stem Cell Differentiation and Bone Regeneration

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