Adenosine receptor agonism protects against NETosis and thrombosis in antiphospholipid syndrome

scientific article published on 23 April 2019

Adenosine receptor agonism protects against NETosis and thrombosis in antiphospholipid syndrome is …
instance of (P31):
scholarly articleQ13442814

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P819ADS bibcode2019NatCo..10.1916A
P356DOI10.1038/S41467-019-09801-X
P932PMC publication ID6478874
P698PubMed publication ID31015489

P50authorYogendra KanthiQ59149661
Shanea K EstesQ123337184
P2093author name stringJason S Knight
He Meng
Jose A Diaz
David J Pinsky
Srilakshmi Yalavarthi
Alex A Gandhi
Paula L Bockenstedt
Joan M Greve
Andrew P Vreede
Olivia R Palmer
Ramadan A Ali
P2860cites workHigh affinity binding of beta 2-glycoprotein I to human endothelial cells is mediated by annexin IIQ22254095
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Monocytes, neutrophils, and platelets cooperate to initiate and propagate venous thrombosis in mice in vivo.Q35894194
Compartmentalisation of phosphodiesterases and protein kinase A: opposites attractQ36156003
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Neutrophil histone modification by peptidylarginine deiminase 4 is critical for deep vein thrombosis in mice.Q36884300
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Ubiquinol Effects on Antiphospholipid Syndrome Prothrombotic Profile: A Randomized, Placebo-Controlled TrialQ38374450
The Role of Reactive Oxygen Species (ROS) in the Formation of Extracellular Traps (ETs) in Humans.Q38462105
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Global Prevalence of Spondyloarthritis: A Systematic Review and Meta-Regression AnalysisQ38682092
Adenosine and adenosine receptors in the pathogenesis and treatment of rheumatic diseasesQ39004042
Neutrophil Extracellular Traps in Atherosclerosis and AtherothrombosisQ39139748
In Vivo Role of Neutrophil Extracellular Traps in Antiphospholipid Antibody-Mediated Venous ThrombosisQ39328138
Beta2-glycoprotein I (beta2-GPI) mRNA is expressed by several cell types involved in anti-phospholipid syndrome-related tissue damageQ40975353
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Release of neutrophil extracellular traps by neutrophils stimulated with antiphospholipid antibodies: a newly identified mechanism of thrombosis in the antiphospholipid syndrome.Q41818166
Activated signature of antiphospholipid syndrome neutrophils reveals potential therapeutic targetQ42162703
Secondary stroke prevention with low-dose aspirin, sustained release dipyridamole alone and in combination. ESPS Investigators. European Stroke Prevention StudyQ42538886
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Characterization of monocyte tissue factor activity induced by IgG antiphospholipid antibodies and inhibition by dilazepQ44958578
Comparison of simultaneous measurement of mouse systolic arterial blood pressure by radiotelemetry and tail-cuff methodsQ47205852
Is leukocyte tissue factor the key to venous thrombosis in antiphospholipid syndrome?Q52884718
Regadenoson pharmacokinetics and tolerability in subjects with impaired renal function.Q53567783
Adenosine 2A receptor is protective against renal injury in MRL/lpr mice.Q54395725
Degradation of neutrophil extracellular traps is decreased in patients with antiphospholipid syndrome.Q54505081
Ectonucleotidase-Mediated Suppression of Lupus Autoimmunity and Vascular Dysfunction.Q55475388
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The anti-beta2-glycoprotein I activity in human anti-phospholipid syndrome sera is due to monoreactive low-affinity autoantibodies directed to epitopes located on native beta2-glycoprotein I and preserved during species' evolutionQ56903194
Anti–β2-glycoprotein I antibodies induce monocyte release of tumor necrosis factor α and tissue factor by signal transduction pathways involving lipid raftsQ59140753
Prevention of perinatal consequences of pre-eclampsia with low-dose aspirin: results of the epreda trial. The Epreda Trial Study GroupQ67773954
Protein kinase A downregulates the phosphorylation of p47 phox in human neutrophils: a possible pathway for inhibition of the respiratory burstQ71617131
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Neutrophil extracellular traps promote thrombin generation through platelet-dependent and platelet-independent mechanismsQ87381493
Neutrophil extracellular trap release is associated with antinuclear antibodies in systemic lupus erythematosus and anti-phospholipid syndromeQ88244848
Anti-β2GPI/β2GPI induces neutrophil extracellular traps formation to promote thrombogenesis via the TLR4/MyD88/MAPKs axis activationQ89043558
Randomized phase 2 trial of regadenoson for treatment of acute vaso-occlusive crises in sickle cell diseaseQ89777309
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P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue1
P407language of work or nameEnglishQ1860
P921main subjectthrombosisQ261327
antiphospholipid syndromeQ582207
P304page(s)1916
P577publication date2019-04-23
P1433published inNature CommunicationsQ573880
P1476titleAdenosine receptor agonism protects against NETosis and thrombosis in antiphospholipid syndrome
P478volume10

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cites work (P2860)
Q94940476Antiphospholipid Syndrome
Q110245879COVID-19 and antiphospholipid antibodies: A position statement and management guidance from AntiPhospholipid Syndrome Alliance for Clinical Trials and InternatiOnal Networking (APS ACTION)
Q104492300COVID-19 and autoimmune diseases
Q104559093COVID-19 in patients with systemic lupus erythematosus: lessons learned from the inflammatory disease
Q99604381Do free radical NETwork and oxidative stress disparities in African Americans enhance their vulnerability to SARS-CoV-2 infection and COVID-19 severity?
Q98177260Emerging role of NET inhibitors in cardiovascular diseases
Q90093923Extracellular DNA NET-Works With Dire Consequences for Health
Q97518173Harnessing adenosine A2A receptors as a strategy for suppressing the lung inflammation and thrombotic complications of COVID-19: Potential of pentoxifylline and dipyridamole
Q90090302Imaging of the immune system - towards a subcellular and molecular understanding
Q98181529Management of anticoagulant-refractory thrombotic antiphospholipid syndrome
Q92097321NETs spread ever wider in rheumatic diseases
Q91752666Preventing NETosis to reduce thrombosis

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