Application of a sequential multiple assignment randomized trial (SMART) design in older patients with chronic lymphocytic leukemia

scientific article published on 01 April 2019

Application of a sequential multiple assignment randomized trial (SMART) design in older patients with chronic lymphocytic leukemia is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1093/ANNONC/MDZ053
P932PMC publication ID6735877
P698PubMed publication ID30799502

P50authorMarie DavidianQ42138537
Anastasios TsiatisQ44796457
P2093author name stringJ Yin
A S Ruppert
J C Byrd
J A Woyach
S J Mandrekar
P2860cites workSalvage therapy for CLL and the role of stem cell transplantationQ46817167
Adaptive therapy for androgen-independent prostate cancer: a randomized selection trial of four regimensQ46923051
Single-agent ibrutinib in treatment-naïve and relapsed/refractory chronic lymphocytic leukemia: a 5-year experienceQ50044415
Venetoclax-Rituximab in Relapsed or Refractory Chronic Lymphocytic Leukemia.Q52644817
Ibrutinib Regimens versus Chemoimmunotherapy in Older Patients with Untreated CLLQ64120393
Two-stage randomization designs in drug developmentQ81499185
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Ibrutinib plus obinutuzumab versus chlorambucil plus obinutuzumab in first-line treatment of chronic lymphocytic leukaemia (iLLUMINATE): a multicentre, randomised, open-label, phase 3 trialQ90315525
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Reinforcement learning design for cancer clinical trialsQ24648505
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Experimental design and primary data analysis methods for comparing adaptive interventionsQ30571530
A randomized, controlled phase III study of cyclophosphamide, doxorubicin, and vincristine with etoposide (CAV-E) or teniposide (CAV-T), followed by recombinant interferon-alpha maintenance therapy or observation, in small cell lung carcinoma patienQ33501129
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Bruton tyrosine kinase represents a promising therapeutic target for treatment of chronic lymphocytic leukemia and is effectively targeted by PCI-32765.Q34026194
Estimation of survival distributions of treatment policies in two-stage randomization designs in clinical trialsQ34117988
An experimental design for the development of adaptive treatment strategiesQ34374570
Dynamic treatment regimes: practical design considerationsQ34466674
Targeting BCL2 with Venetoclax in Relapsed Chronic Lymphocytic LeukemiaQ34504188
Granulocyte-macrophage colony-stimulating factor after initial chemotherapy for elderly patients with primary acute myelogenous leukemia. Cancer and Leukemia Group B.Q34722375
SMART designs in cancer research: Past, present, and futureQ35607162
Pharmacological and Protein Profiling Suggests Venetoclax (ABT-199) as Optimal Partner with Ibrutinib in Chronic Lymphocytic LeukemiaQ35958056
Evaluation of Viable Dynamic Treatment Regimes in a Sequentially Randomized Trial of Advanced Prostate CancerQ36206859
Ibrutinib as Initial Therapy for Patients with Chronic Lymphocytic LeukemiaQ36490049
Sequential multiple-assignment randomized trial design of neurobehavioral treatment for patients with metastatic malignant melanoma undergoing high-dose interferon-alpha therapyQ37434825
Phase II design: history and evolutionQ38405280
Beyond efficacy: the STAR*D trialQ43253972
P433issue4
P407language of work or nameEnglishQ1860
P921main subjectchronic lymphocytic leukemiaQ1088156
Randomized Clinical TrialsQ60716104
P304page(s)542-550
P577publication date2019-04-01
P1433published inAnnals of OncologyQ326122
P1476titleApplication of a sequential multiple assignment randomized trial (SMART) design in older patients with chronic lymphocytic leukemia
P478volume30

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