siRNA-silencing of CD40 attenuates unilateral ureteral obstruction-induced kidney injury in mice

scientific article published on 12 April 2019

siRNA-silencing of CD40 attenuates unilateral ureteral obstruction-induced kidney injury in mice is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1371/JOURNAL.PONE.0215232
P932PMC publication ID6461348
P698PubMed publication ID30978213

P50authorAlonso Narváez BarrosQ91726802
P2093author name stringJuan Morote
Josep M Cruzado
Josep M Grinyó
Juan Torras
Anna Sola
Roser Guiteras
Anna Manonelles
P2860cites workMacrophage in chronic kidney diseaseQ28068907
CD40 gene silencing reduces the progression of experimental lupus nephritis modulating local milieu and systemic mechanismsQ28533954
Recovery from release of ureteral obstruction in the rat: relationship to nephrogenesisQ30309386
Congenital urinary tract obstruction: Proceedings of the State-Of-The-Art Strategic Planning Workshop—National Institutes of Health, Bethesda, Maryland, USA, 11–12 March 2002Q30310812
Matrix metalloproteinase-9 of tubular and macrophage origin contributes to the pathogenesis of renal fibrosis via macrophage recruitment through osteopontin cleavage.Q51835071
Immunological function of tubular epithelial cells: the functional implications of CD40 expression.Q54519152
CD40: an upstream master switch for endothelial cell activation uncovered by RNAi-coupled transcriptional profilingQ81724807
Mechanisms of tubulointerstitial fibrosisQ85074102
Kidney keratins: cytoskeletal stress responders with biomarker potentialQ87495645
Pathogenesis of renal injury in obstructive uropathyQ30440178
Ureteral obstruction as a model of renal interstitial fibrosis and obstructive nephropathyQ30448126
Counterbalance in functional adaptation to ureteral obstruction during developmentQ30454626
Chronic kidney disease induced in mice by reversible unilateral ureteral obstruction is dependent on genetic backgroundQ33783980
Chitosan/siRNA nanoparticles targeting cyclooxygenase type 2 attenuate unilateral ureteral obstruction-induced kidney injury in mice.Q34785218
Chemokine receptor Cxcr4 contributes to kidney fibrosis via multiple effectorsQ35138504
The CD154-CD40 T-cell co-stimulation pathway in liver ischemia and reperfusion inflammatory responsesQ35751635
Hepatocyte growth factor gene therapy enhances infiltration of macrophages and may induce kidney repair in db/db mice as a model of diabetesQ36013538
The role of tubular epithelial-mesenchymal transition in progressive kidney disease.Q36857879
Molecular mechanism and function of CD40/CD40L engagement in the immune system.Q37474929
The CD40/CD40L system: a new therapeutic target for diseaseQ38124660
Inflammatory processes in renal fibrosis.Q38225047
HuangQi Decoction Ameliorates Renal Fibrosis via TGF-β/Smad Signaling Pathway In Vivo and In VitroQ38772145
RNAi-Based Therapy in Experimental Ischemia-Reperfusion Injury. The New TargetsQ38924115
Reimplantation of the ureter after unilateral ureteral obstruction provides a model that allows functional evaluationQ39324919
CD154-CD40 T-cell co-stimulation pathway is a key mechanism in kidney ischemia-reperfusion injuryQ40919282
Expression of functional CD40 by vascular endothelial cellsQ41981036
In vivo therapeutic efficacy of intra-renal CD40 silencing in a model of humoral acute rejectionQ45869121
Renal structural and functional repair in a mouse model of reversal of ureteral obstructionQ46750147
Macrophage Overexpressing NGAL Ameliorated Kidney Fibrosis in the UUO Mice ModelQ47677757
Silencing of CD40 in vivo reduces progression of experimental atherogenesis through an NF-κB/miR-125b axis and reveals new potential mediators in the pathogenesis of atherosclerosisQ47993155
Renal functional decline and glomerulotubular injury are arrested but not restored by release of unilateral ureteral obstruction (UUO).Q48109439
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue4
P407language of work or nameEnglishQ1860
P921main subjectkidney diseaseQ1054718
P304page(s)e0215232
P577publication date2019-04-12
P1433published inPLOS OneQ564954
P1476titlesiRNA-silencing of CD40 attenuates unilateral ureteral obstruction-induced kidney injury in mice
P478volume14

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