A Leukocyte Infiltration Score Defined by a Gene Signature Predicts Melanoma Patient Prognosis

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A Leukocyte Infiltration Score Defined by a Gene Signature Predicts Melanoma Patient Prognosis is …
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scholarly articleQ13442814

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P356DOI10.1158/1541-7786.MCR-18-0173
P932PMC publication ID6318018
P698PubMed publication ID30171176

P50authorEva HernandoQ40230064
Chao ChengQ87770555
P2093author name stringChristopher I Amos
Ronglai Shen
Nancy E Thomas
Marianne Berwick
Mary Jo Turk
Yanding Zhao
Ivan P Gorlov
Evelien Schaafsma
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Genomic correlates of response to CTLA-4 blockade in metastatic melanomaQ37319470
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Systematic Pan-Cancer Analysis Reveals Immune Cell Interactions in the Tumor Microenvironment.Q38996594
Tumor aneuploidy correlates with markers of immune evasion and with reduced response to immunotherapy.Q39011183
CDK4/6 inhibition triggers anti-tumour immunity.Q40081387
A Novel Numerical Scoring System for Melanoma Tumor-infiltrating Lymphocytes Has Better Prognostic Value Than Standard ScoringQ40262319
HYPE or HOPE: the prognostic value of infiltrating immune cells in cancerQ41431266
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Paucity of tumor-infiltrating lymphocytes is an unfavorable prognosticator and predicts lymph node metastases in cutaneous melanoma patients.Q43627503
Determination of prognosis in metastatic melanoma through integration of clinico-pathologic, mutation, mRNA, microRNA, and protein information.Q44133547
Pan-cancer Immunogenomic Analyses Reveal Genotype-Immunophenotype Relationships and Predictors of Response to Checkpoint Blockade.Q45949028
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Mutational and putative neoantigen load predict clinical benefit of adoptive T cell therapy in melanomaQ47157659
A P53-Deficiency Gene Signature Predicts Recurrence Risk of Patients with Early-Stage Lung AdenocarcinomaQ47590835
Tumor Infiltrating Lymphocytes (TILs) May be Only an Independent Predictor of Nodal Involvement but not for Recurrence and Survival in Cutaneous Melanoma PatientsQ48252817
Gene expression profiling-based identification of molecular subtypes in stage IV melanomas with different clinical outcomeQ48661799
A seven-gene prognostic signature for rapid determination of head and neck squamous cell carcinoma survivalQ49525456
Predictive gene signature in MAGE-A3 antigen-specific cancer immunotherapy.Q50954469
Correlation between Density of CD8+ T-cell Infiltrate in Microsatellite Unstable Colorectal Cancers and Frameshift Mutations: A Rationale for Personalized Immunotherapy.Q50965911
A pan-cancer landscape of interactions between solid tumors and infiltrating immune cell populations.Q52582134
Spatial Organization and Molecular Correlation of Tumor-Infiltrating Lymphocytes Using Deep Learning on Pathology Images.Q55036914
MelanomaQ57571848
Immune cells in the melanoma microenvironment hold information for prediction of the risk of recurrence and response to treatmentQ59275946
Tumor infiltrating lymphocytes in lymph node melanoma metastases: a histopathologic prognostic indicator and an expression of local immune responseQ70918943
P433issue1
P407language of work or nameEnglishQ1860
P304page(s)109-119
P577publication date2018-08-31
P1433published inMolecular Cancer ResearchQ2751014
P1476titleA Leukocyte Infiltration Score Defined by a Gene Signature Predicts Melanoma Patient Prognosis
P478volume17

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cites work (P2860)
Q89884092Decreasing Microtubule Actin Cross-Linking Factor 1 Inhibits Melanoma Metastasis by Decreasing Epithelial to Mesenchymal Transition
Q92746202Immunological analyses reveal an immune subtype of uveal melanoma with a poor prognosis
Q91759638Molecular Profiling Reveals Unique Immune and Metabolic Features of Melanoma Brain Metastases

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