The lyase activity of bifunctional DNA glycosylases and the 3'-diesterase activity of APE1 contribute to the repair of oxidized bases in nucleosomes

The lyase activity of bifunctional DNA glycosylases and the 3'-diesterase activity of APE1 contribute to the repair of oxidized bases in nucleosomes is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1093/NAR/GKY1315
P932PMC publication ID6451105
P698PubMed publication ID30649547

P50authorSusan S WallaceQ41886664
P2093author name stringRobyn L Maher
David S Pederson
P2860cites workCrystal structure of the nucleosome core particle at 2.8 A resolutionQ22122355
Instability and decay of the primary structure of DNAQ22122361
DNA-bound structures and mutants reveal abasic DNA binding by APE1 and DNA repair coordination [corrected]Q27621279
Chromatin remodelling complex RSC promotes base excision repair in chromatin of Saccharomyces cerevisiaeQ27933831
Substrate specificity of human endonuclease III (hNTH1). Effect of human APE1 on hNTH1 activityQ28202324
Nucleosome disruption by DNA ligase III-XRCC1 promotes efficient base excision repairQ28248511
Endogenous DNA damage in humans: a review of quantitative dataQ28259993
A germline homozygous mutation in the base-excision repair gene NTHL1 causes adenomatous polyposis and colorectal cancerQ28261506
Stimulation of human 8-oxoguanine-DNA glycosylase by AP-endonuclease: potential coordination of the initial steps in base excision repairQ28645611
Base-excision repair of oxidative DNA damageQ29615373
The role of the N-terminal domain of human apurinic/apyrimidinic endonuclease 1, APE1, in DNA glycosylase stimulation.Q52373868
Growth retardation and dyslymphopoiesis accompanied by G2/M arrest in APEX2-null mice.Q54705178
Passing the baton in base excision repairQ73505096
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DNA scanning by base excision repair enzymes and implications for pathway coordinationQ91287415
Escherichia coli double-strand uracil-DNA glycosylase: involvement in uracil-mediated DNA base excision repair and stimulation of activity by endonuclease IV.Q30909777
DNA polymerase β uses its lyase domain in a processive search for DNA damageQ33580434
Base excision repair: a critical player in many gamesQ33908163
Expression and purification of recombinant histones and nucleosome reconstitutionQ33914576
Nucleosomes suppress the formation of double-strand DNA breaks during attempted base excision repair of clustered oxidative damagesQ33931095
Impact of abasic site orientation within nucleosomes on human APE1 endonuclease activity.Q33956975
Expression of DNA polymerase {beta} cancer-associated variants in mouse cells results in cellular transformationQ34063561
Mechanism of stimulation of the DNA glycosylase activity of hOGG1 by the major human AP endonuclease: bypass of the AP lyase activity stepQ34286685
Reconstitution of nucleosome core particles from recombinant histones and DNA.Q34296889
Substrate channeling in mammalian base excision repair pathways: passing the batonQ34412541
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Efficient cleavage of single and clustered AP site lesions within mono-nucleosome templates by CHO-K1 nuclear extract contrasts with retardation of incision by purified APE1.Q36306861
Rules of engagement for base excision repair in chromatinQ36309928
Apurinic/apyrimidinic endonuclease 1 is the essential nuclease during immunoglobulin class switch recombinationQ36759880
The structural location of DNA lesions in nucleosome core particles determines accessibility by base excision repair enzymesQ36832725
Germ-line variant of human NTH1 DNA glycosylase induces genomic instability and cellular transformationQ37143498
Contribution of DNA unwrapping from histone octamers to the repair of oxidatively damaged DNA in nucleosomesQ37424412
Human apurinic/apyrimidinic endonuclease 1.Q37512952
Co-ordination of base excision repair and genome stabilityQ38087704
The HAP1 protein stimulates the turnover of human mismatch-specific thymine-DNA-glycosylase to process 3,N(4)-ethenocytosine residuesQ38297764
Human thymine DNA glycosylase binds to apurinic sites in DNA but is displaced by human apurinic endonuclease 1.Q38330113
Initiation of base excision repair of oxidative lesions in nucleosomes by the human, bifunctional DNA glycosylase NTH1.Q41886603
Polymorphism of apyrimidinic DNA structures in the nucleosomeQ41900476
Enzymatic excision of uracil residues in nucleosomes depends on the local DNA structure and dynamicsQ42029581
Alternative nucleotide incision repair pathway for oxidative DNA damageQ43863362
Human cells contain a factor that facilitates the DNA glycosylase-mediated excision of oxidized bases from occluded sites in nucleosomesQ46335843
The Human Ligase IIIα-XRCC1 Protein Complex Performs DNA Nick Repair after Transient Unwrapping of Nucleosomal DNA.Q46420229
Genome-wide maps of alkylation damage, repair, and mutagenesis in yeast reveal mechanisms of mutational heterogeneity.Q47982607
P275copyright licenseCreative Commons Attribution-NonCommercial 4.0 InternationalQ34179348
P6216copyright statuscopyrightedQ50423863
P433issue6
P407language of work or nameEnglishQ1860
P304page(s)2922-2931
P577publication date2019-04-08
P1433published inNucleic Acids ResearchQ135122
P1476titleThe lyase activity of bifunctional DNA glycosylases and the 3'-diesterase activity of APE1 contribute to the repair of oxidized bases in nucleosomes
P478volume47

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