Variation in the repulsive guidance molecule family in human populations

scientific article published on 01 February 2019

Variation in the repulsive guidance molecule family in human populations is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.14814/PHY2.13959
P932PMC publication ID6370684
P698PubMed publication ID30746893

P50authorPeter RotweinQ56013910
P2093author name stringPeter Rotwein
P2860cites workHemojuvelin and bone morphogenetic protein (BMP) signaling in iron homeostasisQ21129271
Pro-protein convertases control the maturation and processing of the iron-regulatory protein, RGMc/hemojuvelinQ21284382
DRAGON, a bone morphogenetic protein co-receptorQ24292739
Furin-mediated release of soluble hemojuvelin: a new link between hypoxia and iron homeostasisQ24297889
Neogenin interacts with hemojuvelin through its two membrane-proximal fibronectin type III domainsQ24310451
Hemojuvelin is essential for dietary iron sensing, and its mutation leads to severe iron overloadQ24312272
Deleted in Colorectal Cancer (DCC) encodes a netrin receptorQ24313278
Hemojuvelin regulates hepcidin expression via a selective subset of BMP ligands and receptors independently of neogeninQ24321923
A mouse model of juvenile hemochromatosisQ24532268
Analysis of protein-coding genetic variation in 60,706 humansQ26831376
Understanding rare and common diseases in the context of human evolutionQ28067740
New insights into the generation and role of de novo mutations in health and diseaseQ28073446
The serine protease matriptase-2 (TMPRSS6) inhibits hepcidin activation by cleaving membrane hemojuvelinQ28115763
Vertebrate homologues of C. elegans UNC-5 are candidate netrin receptorsQ28118661
RGMs: Structural Insights, Molecular Regulation, and Downstream SignalingQ39050838
Targeting repulsive guidance molecule A to promote regeneration and neuroprotection in multiple sclerosis.Q41175140
A high-coverage Neandertal genome from Vindija Cave in Croatia.Q46270621
Genetic effects on gene expression across human tissuesQ46285732
The Contribution of Neanderthals to Phenotypic Variation in Modern HumansQ47189890
Repulsive guidance molecule plays multiple roles in neuronal differentiation and axon guidance.Q48515205
Enhancing GTEx by bridging the gaps between genotype, gene expression, and disease.Q50093911
Gene discovery by microarray: identification of novel genes induced during growth factor-mediated muscle cell survival and differentiation.Q52086790
Levodopa increases oxidative stress and repulsive guidance molecule A levels: a pilot study in patients with Parkinson's disease.Q52855994
Repulsive guidance molecule-a is involved in Th17-cell-induced neurodegeneration in autoimmune encephalomyelitis.Q55069657
RGMa modulates T cell responses and is involved in autoimmune encephalomyelitisQ56771929
Meta-analysis of genome-wide association studies for height and body mass index in ∼700000 individuals of European ancestryQ57463053
Genome-wide polygenic scores for common diseases identify individuals with risk equivalent to monogenic mutationsQ57910661
Genetic variation: ExAC boosts clinical variant interpretation in rare diseasesQ64047944
Neogenin-RGMa signaling at the growth cone is bone morphogenetic protein-independent and involves RhoA, ROCK, and PKCQ80050476
HJV gene mutations in European patients with juvenile hemochromatosisQ81614831
Organization of GPI-anchored proteins at the cell surface and its physiopathological relevanceQ90440775
Mutations in HFE2 cause iron overload in chromosome 1q-linked juvenile hemochromatosisQ28188379
Isolation and expression pattern of three mouse homologues of chick RgmQ28191703
RGM is a repulsive guidance molecule for retinal axonsQ28204359
DRAGON: a member of the repulsive guidance molecule-related family of neuronal- and muscle-expressed membrane proteins is regulated by DRG11 and has neuronal adhesive propertiesQ28246971
Complex biosynthesis of the muscle-enriched iron regulator RGMcQ28254101
Molecular biology, genetics and biochemistry of the repulsive guidance molecule familyQ28255922
The cBio cancer genomics portal: an open platform for exploring multidimensional cancer genomics dataQ28266682
Selective binding of RGMc/hemojuvelin, a key protein in systemic iron metabolism, to BMP-2 and neogeninQ28269309
Neogenin mediates the action of repulsive guidance moleculeQ28272500
RGM and its receptor neogenin regulate neuronal survivalQ28272510
Integrative analysis of complex cancer genomics and clinical profiles using the cBioPortalQ28288215
Dependence receptors: when apoptosis controls tumor progressionQ28298762
Repulsive guidance molecule (RGM) gene function is required for neural tube closure but not retinal topography in the mouse visual systemQ28506752
Repulsive guidance molecule (RGMa), a DRAGON homologue, is a bone morphogenetic protein co-receptorQ28510682
RGMa inhibition promotes axonal growth and recovery after spinal cord injury.Q28571215
Upper Palaeolithic genomes reveal deep roots of modern EurasiansQ29544409
New fossils from Jebel Irhoud, Morocco and the pan-African origin of Homo sapiensQ30156627
Spectrum of hemojuvelin gene mutations in 1q-linked juvenile hemochromatosis.Q30339036
HFE gene: Structure, function, mutations, and associated iron abnormalities.Q30380172
The global prevalence of HFE and non-HFE hemochromatosis estimated from analysis of next-generation sequencing data.Q31030085
The ExAC browser: displaying reference data information from over 60 000 exomesQ31145461
Small Amounts of Archaic Admixture Provide Big Insights into Human HistoryQ34045116
The dependence receptors DCC and UNC5H as a link between neuronal guidance and survivalQ35575340
Dragon (repulsive guidance molecule b, RGMb) is a novel gene that promotes colorectal cancer growthQ36299749
The RGM/DRAGON family of BMP co-receptorsQ37026226
Repulsive guidance molecule B inhibits metastasis and is associated with decreased mortality in non-small cell lung cancerQ37085857
Patterns of genic intolerance of rare copy number variation in 59,898 human exomesQ37297685
The continuum of causality in human genetic disordersQ37422176
The neurophysiology of the esophagusQ38151803
Human occupation of northern Australia by 65,000 years ago.Q38369079
The New Genomics: What Molecular Databases Can Tell us About Human Population Variation and Endocrine DiseaseQ38789207
TGF-β and the TGF-β Family: Context-Dependent Roles in Cell and Tissue PhysiologyQ38824306
Large-scale analysis of variation in the insulin-like growth factor family in humans reveals rare disease links and common polymorphisms.Q38847165
TGF-β Signaling from Receptors to SmadsQ38906099
P433issue3
P407language of work or nameEnglishQ1860
P921main subjectHemojuvelinQ24766888
HemochromatosisQ61508171
P304page(s)e13959
P577publication date2019-02-01
P1433published inPhysiological ReportsQ15716763
P1476titleVariation in the repulsive guidance molecule family in human populations
P478volume7

Reverse relations

cites work (P2860)
Q99578689ZMAT2 in Humans and Other Primates: A Highly Conserved and Understudied Gene
Q89471084Zmat2 in mammals: conservation and diversification among genes and Pseudogenes

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