Beneficial effects of 6-shogaol on hyperglycemia, islet morphology and apoptosis in some tissues of streptozotocin-induced diabetic mice

Beneficial effects of 6-shogaol on hyperglycemia, islet morphology and apoptosis in some tissues of streptozotocin-induced diabetic mice is …
instance of (P31):
scholarly articleQ13442814

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P6179Dimensions Publication ID1112088403
P356DOI10.1186/S13098-019-0407-0
P932PMC publication ID6373041
P698PubMed publication ID30805033

P2093author name stringZae-Young Ryoo
Sung-Hyun Kim
Dong-Yep Oh
Myoung-Ok Kim
Jun-Koo Yi
Jae-Jung Ha
P2860cites workNrf2 is critical in defense against high glucose-induced oxidative damage in cardiomyocytesQ24170228
The mechanism of alloxan and streptozotocin action in B cells of the rat pancreasQ28217509
Analgesic, antiinflammatory and hypoglycaemic effects of ethanol extract of Zingiber officinale (Roscoe) rhizomes (Zingiberaceae) in mice and ratsQ28221113
Pharmacological studies on Ginger. I. Pharmacological actions of pungent constituents, (6)-gingerol and (6)-shogaolQ28266216
Metabolic profiling and phylogenetic analysis of medicinal Zingiber species: Tools for authentication of ginger (Zingiber officinale Rosc)Q28272751
Definition, diagnosis and classification of diabetes mellitus and its complications. Part 1: diagnosis and classification of diabetes mellitus provisional report of a WHO consultationQ29547453
Oxidative Stress and Diabetic ComplicationsQ29615423
CKD classification based on estimated GFR over three years and subsequent cardiac and mortality outcomes: a cohort studyQ33504418
The protective role of Nrf2 in streptozotocin-induced diabetic nephropathyQ33750711
Prime role for an insulin epitope in the development of type 1 diabetes in NOD miceQ34345367
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Ginger: an ethnomedical, chemical and pharmacological reviewQ34494797
Anti-tumor promoting potential of selected spice ingredients with antioxidative and anti-inflammatory activities: a short reviewQ34687878
Oxidative stress: the lead or supporting actor in the pathogenesis of diabetic complicationsQ35182343
Changes in hepatic glutathione metabolism in diabetes.Q51611790
Tumor necrosis factor alpha pathways develops liver apoptosis in type 1 diabetes mellitus.Q54597502
Are we overestimating the loss of beta cells in type 2 diabetes?Q57502872
Impaired antioxidant status in diabetic rat liver. Effect of vanadateQ70584156
Hepatomegaly and abnormal liver tests due to glycogenosis in adults with diabetesQ71941748
Neuroprotective effect of ginger on anti-oxidant enzymes in streptozotocin-induced diabetic ratsQ83027360
6-shogaol-rich extract from ginger up-regulates the antioxidant defense systems in cells and miceQ84523544
Opposite Expression of SPARC between the Liver and Pancreas in Streptozotocin-Induced Diabetic RatsQ35674489
10-Shogaol, an antioxidant from Zingiber officinale for skin cell proliferation and migration enhancerQ35795804
Advances in the understanding of diabetes mellitus.Q35933092
Pancreatic β cell dedifferentiation as a mechanism of diabetic β cell failureQ36241895
Liver disease in patients with diabetes mellitusQ36337748
Cancer preventive properties of ginger: a brief reviewQ36686672
Some phytochemical, pharmacological and toxicological properties of ginger (Zingiber officinale Roscoe): a review of recent researchQ36976622
Ginger-derived phenolic substances with cancer preventive and therapeutic potentialQ37444533
Oxidative stress, diabetes, and diabetic complicationsQ37613032
Potential role of acid sphingomyelinase in environmental healthQ38007788
A review of the gastroprotective effects of ginger (Zingiber officinale Roscoe).Q38101239
The role of antioxidants and other agents in alleviating hyperglycemia mediated oxidative stress and injury in liverQ38113967
Diabetic downregulation of Nrf2 activity via ERK contributes to oxidative stress-induced insulin resistance in cardiac cells in vitro and in vivoQ39602218
Comparative antioxidant and anti-inflammatory effects of [6]-gingerol, [8]-gingerol, [10]-gingerol and [6]-shogaolQ39787081
Ginger-chemistry, technology, and quality evaluation: part 2.Q40248784
Ginger--chemistry, technology, and quality evaluation: part 1.Q40336062
Exacerbation of diabetes-induced testicular apoptosis by zinc deficiency is most likely associated with oxidative stress, p38 MAPK activation, and p53 activation in miceQ42813352
Anti-invasion effects of 6-shogaol and 6-gingerol, two active components in ginger, on human hepatocarcinoma cellsQ43045570
6-Shogaol is more effective than 6-gingerol and curcumin in inhibiting 12-O-tetradecanoylphorbol 13-acetate-induced tumor promotion in miceQ43119184
Hyperglycemia induces apoptosis in rat liver through the increase of hydroxyl radical: new insights into the insulin effectQ43158686
[6]-Gingerol inhibits nitric oxide synthesis in activated J774.1 mouse macrophages and prevents peroxynitrite-induced oxidation and nitration reactionsQ44628254
[6]-Gingerol inhibits COX-2 expression by blocking the activation of p38 MAP kinase and NF-kappaB in phorbol ester-stimulated mouse skinQ45286157
Toxicological investigation of acute and chronic treatment with Gnidia stenophylla Gilg root extract on some blood parameters and histopathology of spleen, liver and kidney in miceQ46156669
Hyperglycemia induces oxidative and nitrosative stress and increases renal functional impairment in Nrf2-deficient mice.Q46193503
Antioxidant effect of Aloe vera gel extract in streptozotocin-induced diabetes in ratsQ46453629
Cytotoxic, cytoprotective and antioxidant effects of isolated phenolic compounds from fresh gingerQ48711550
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue1
P407language of work or nameEnglishQ1860
P921main subjecthyperglycemiaQ271993
P304page(s)15
P577publication date2019-01-01
P1433published inDiabetology and Metabolic SyndromeQ15816649
P1476titleBeneficial effects of 6-shogaol on hyperglycemia, islet morphology and apoptosis in some tissues of streptozotocin-induced diabetic mice
P478volume11

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cites work (P2860)
Q907500746-Shogaol Inhibits Advanced Glycation End-Products-Induced IL-6 and ICAM-1 Expression by Regulating Oxidative Responses in Human Gingival Fibroblasts
Q93007222Steamed Ginger May Enhance Insulin Secretion through KATP Channel Closure in Pancreatic β-Cells Potentially by Increasing 1-Dehydro-6-Gingerdione Content
Q92646761The antagonism of 6-shogaol in high-glucose-activated NLRP3 inflammasome and consequent calcification of human artery smooth muscle cells

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