PRRs and NB-LRRs: From Signal Perception to Activation of Plant Innate Immunity

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PRRs and NB-LRRs: From Signal Perception to Activation of Plant Innate Immunity is …
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scholarly articleQ13442814
review articleQ7318358

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P356DOI10.3390/IJMS20081882
P932PMC publication ID6514886
P698PubMed publication ID30995767

P50authorYonggen LouQ61126426
Ali NomanQ63148601
Muhammad AqeelQ64215032
P2093author name stringYonggen Lou
Ali Noman
Muhammad Aqeel
P2860cites workOf PAMPs and effectors: the blurred PTI-ETI dichotomyQ24605642
Silencing and innate immunity in plant defense against viral and non-viral pathogensQ27010305
Chitin-induced dimerization activates a plant immune receptorQ27679401
Molecular mechanism for plant steroid receptor activation by somatic embryogenesis co-receptor kinasesQ27685358
Conserved fungal LysM effector Ecp6 prevents chitin-triggered immunity in plants.Q38341524
Plant recognition of symbiotic bacteria requires two LysM receptor-like kinases.Q38349438
Plant NB-LRR proteins: tightly regulated sensors in a complex manner.Q38397046
Understanding plant immunity as a surveillance system to detect invasion.Q38517411
Structural basis for interactions of the Phytophthora sojae RxLR effector Avh5 with phosphatidylinositol 3-phosphate and for host cell entryQ39257655
Function, Discovery, and Exploitation of Plant Pattern Recognition Receptors for Broad-Spectrum Disease Resistance.Q39375550
Genomic screens identify a new phytobacterial microbe-associated molecular pattern and the cognate Arabidopsis receptor-like kinase that mediates its immune elicitationQ39781818
The pattern-recognition receptor CORE of Solanaceae detects bacterial cold-shock proteinQ40433415
Overexpression of a citrus NDR1 ortholog increases disease resistance in ArabidopsisQ41354788
The Brassica napus receptor-like protein RLM2 is encoded by a second allele of the LepR3/Rlm2 blackleg resistance locusQ41490982
Avirulence protein 3a (AVR3a) from the potato pathogen Phytophthora infestans forms homodimers through its predicted translocation region and does not specifically bind phospholipidsQ41521481
An RLP23-SOBIR1-BAK1 complex mediates NLP-triggered immunityQ41573598
Terrific protein traffic: the mystery of effector protein delivery by filamentous plant pathogensQ41957294
Arabidopsis MAP kinase 4 regulates gene expression through transcription factor release in the nucleusQ42405759
The lysin motif receptor-like kinase (LysM-RLK) CERK1 is a major chitin-binding protein in Arabidopsis thaliana and subject to chitin-induced phosphorylationQ42428016
Specific threonine phosphorylation of a host target by two unrelated type III effectors activates a host innate immune receptor in plantsQ42483983
The membrane-anchored BOTRYTIS-INDUCED KINASE1 plays distinct roles in Arabidopsis resistance to necrotrophic and biotrophic pathogensQ42487716
Mutational analysis of the Arabidopsis nucleotide binding site-leucine-rich repeat resistance gene RPS2.Q42498197
Nuclear activity of MLA immune receptors links isolate-specific and basal disease-resistance responses.Q42505990
RIN4 interacts with Pseudomonas syringae type III effector molecules and is required for RPM1-mediated resistance in ArabidopsisQ42520168
Nuclear accumulation of the Arabidopsis immune receptor RPS4 is necessary for triggering EDS1-dependent defenseQ42521377
Bacterial genes involved in type I secretion and sulfation are required to elicit the rice Xa21-mediated innate immune responseQ42629307
A functional screen for the type III (Hrp) secretome of the plant pathogen Pseudomonas syringae.Q42671228
Mutations in the NB-ARC domain of I-2 that impair ATP hydrolysis cause autoactivation.Q42680832
A receptor-like cytoplasmic kinase phosphorylates the host target RIN4, leading to the activation of a plant innate immune receptorQ42710152
Perception of the novel MAMP eMax from different Xanthomonas species requires the Arabidopsis receptor-like protein ReMAX and the receptor kinase SOBIR.Q42729600
Arabidopsis thaliana receptor-like protein AtRLP23 associates with the receptor-like kinase AtSOBIR1.Q42730792
Innate immunity in plants: an arms race between pattern recognition receptors in plants and effectors in microbial pathogensQ43066417
PEPR2 is a second receptor for the Pep1 and Pep2 peptides and contributes to defense responses in Arabidopsis.Q43152590
Structure-function analysis of the NB-ARC domain of plant disease resistance proteins.Q43838589
Lysin motif-containing proteins LYP4 and LYP6 play dual roles in peptidoglycan and chitin perception in rice innate immunityQ43992620
LYK4, a lysin motif receptor-like kinase, is important for chitin signaling and plant innate immunity in ArabidopsisQ44124077
External lipid PI3P mediates entry of eukaryotic pathogen effectors into plant and animal host cells.Q44250053
Targeted activation tagging of the Arabidopsis NBS-LRR gene, ADR1, conveys resistance to virulent pathogensQ44541411
A LysM receptor-like kinase plays a critical role in chitin signaling and fungal resistance in Arabidopsis.Q44660600
Overexpression of the plasma membrane-localized NDR1 protein results in enhanced bacterial disease resistance in Arabidopsis thalianaQ44800903
The receptor for the fungal elicitor ethylene-inducing xylanase is a member of a resistance-like gene family in tomatoQ44904965
Tomato receptor FLAGELLIN-SENSING 3 binds flgII-28 and activates the plant immune system.Q45040776
CaWRKY58, encoding a group I WRKY transcription factor of Capsicum annuum, negatively regulates resistance to Ralstonia solanacearum infection.Q45152170
Depletion of the photosystem II core complex in mature tobacco leaves infected by the flavum strain of tobacco mosaic virusQ45706586
Analysis of flagellin perception mediated by flg22 receptor OsFLS2 in riceQ45894840
RD19, an Arabidopsis cysteine protease required for RRS1-R-mediated resistance, is relocalized to the nucleus by the Ralstonia solanacearum PopP2 effector.Q46425669
Arabidopsis EF-Tu receptor enhances bacterial disease resistance in transgenic wheat.Q46761306
Elicitin recognition confers enhanced resistance to Phytophthora infestans in potato.Q46792254
Deciphering physio-biochemical, yield, and nutritional quality attributes of water-stressed radish (Raphanus sativus L.) plants grown from Zn-Lys primed seeds.Q47264617
Gene expression signatures from three genetically separable resistance gene signaling pathways for downy mildew resistanceQ47385928
The MEKK1-MKK1/MKK2-MPK4 kinase cascade negatively regulates immunity mediated by a mitogen-activated protein kinase kinase kinase in ArabidopsisQ47697609
Microarray analysis of chitin elicitation in Arabidopsis thalianaQ47794547
The tomato Cf-5 disease resistance gene and six homologs show pronounced allelic variation in leucine-rich repeat copy numberQ48008619
The tomato Cf-2 disease resistance locus comprises two functional genes encoding leucine-rich repeat proteinsQ48066304
Identification and mutational analysis of Arabidopsis FLS2 leucine-rich repeat domain residues that contribute to flagellin perceptionQ48077050
Distinct domains in the ARC region of the potato resistance protein Rx mediate LRR binding and inhibition of activationQ48086025
Salicylic Acid and Jasmonic Acid Pathways are Activated in Spatially Different Domains Around the Infection Site During Effector-Triggered Immunity in Arabidopsis thaliana.Q48589554
Genome analysis of two novel Pseudomonas strains exhibiting differential hypersensitivity reactions on tobacco seedlings reveals differences in nonflagellar T3SS organization and predicted effector proteins.Q49717962
The plant immune systemQ28131801
RNA silencing as a plant immune system against virusesQ28210891
A type I-secreted, sulfated peptide triggers XA21-mediated innate immunityQ28263841
A simple cipher governs DNA recognition by TAL effectorsQ28265506
A receptor kinase-like protein encoded by the rice disease resistance gene, Xa21Q28270671
Are innate immune signaling pathways in plants and animals conserved?Q28273570
A novel role for the TIR domain in association with pathogen-derived elicitorsQ28469160
RIN4 functions with plasma membrane H+-ATPases to regulate stomatal apertures during pathogen attackQ28475621
The type III effector HopF2Pto targets Arabidopsis RIN4 protein to promote Pseudomonas syringae virulenceQ28492430
A J domain virulence effector of Pseudomonas syringae remodels host chloroplasts and suppresses defensesQ28492431
Flagellin induces innate immunity in nonhost interactions that is suppressed by Pseudomonas syringae effectorsQ28492432
Pseudomonas syringae effector AvrPto blocks innate immunity by targeting receptor kinasesQ28492433
Bacterial effectors target the common signaling partner BAK1 to disrupt multiple MAMP receptor-signaling complexes and impede plant immunityQ28748707
Host-microbe interactions: shaping the evolution of the plant immune responseQ29617734
A renaissance of elicitors: perception of microbe-associated molecular patterns and danger signals by pattern-recognition receptorsQ29618149
Plant immunity: towards an integrated view of plant-pathogen interactionsQ30004699
Pep-13, a plant defense-inducing pathogen-associated pattern from Phytophthora transglutaminases.Q30320728
Alfalfa benefits from Medicago truncatula: the RCT1 gene from M. truncatula confers broad-spectrum resistance to anthracnose in alfalfaQ30483331
No evidence for binding between resistance gene product Cf-9 of tomato and avirulence gene product AVR9 of Cladosporium fulvum.Q30994208
Broad-spectrum mildew resistance in Arabidopsis thaliana mediated by RPW8.Q31805375
Suppression of plant resistance gene-based immunity by a fungal effectorQ33332583
WRR4 encodes a TIR-NB-LRR protein that confers broad-spectrum white rust resistance in Arabidopsis thaliana to four physiological races of Albugo candida.Q33351476
Network properties of robust immunity in plantsQ33518481
The Arabidopsis thaliana RPM1 disease resistance gene product is a peripheral plasma membrane protein that is degraded coincident with the hypersensitive responseQ33618105
Type III secretion machines: bacterial devices for protein delivery into host cellsQ33639326
Autoimmunity in Arabidopsis acd11 is mediated by epigenetic regulation of an immune receptorQ33719427
Rapid heteromerization and phosphorylation of ligand-activated plant transmembrane receptors and their associated kinase BAK1.Q33744516
The Pseudomonas syringae effector AvrRpt2 cleaves its C-terminally acylated target, RIN4, from Arabidopsis membranes to block RPM1 activationQ33772090
Specific resistances against Pseudomonas syringae effectors AvrB and AvrRpm1 have evolved differently in common bean (Phaseolus vulgaris), soybean (Glycine max), and Arabidopsis thaliana.Q34069165
Multiple recognition of RXLR effectors is associated with nonhost resistance of pepper against Phytophthora infestansQ34086552
Identification and localisation of the NB-LRR gene family within the potato genomeQ34159574
Initiation of RPS2-specified disease resistance in Arabidopsis is coupled to the AvrRpt2-directed elimination of RIN4.Q34176705
Arabidopsis EDS1 connects pathogen effector recognition to cell compartment-specific immune responsesQ34239897
Two LysM receptor molecules, CEBiP and OsCERK1, cooperatively regulate chitin elicitor signaling in rice.Q34378470
Resistance gene complexes: evolution and utilizationQ34433618
Pseudomonas type III effector AvrPtoB induces plant disease susceptibility by inhibition of host programmed cell deathQ34446089
Ligand-induced endocytosis of the pattern recognition receptor FLS2 in ArabidopsisQ34471127
Overexpression of a Chinese cabbage BrERF11 transcription factor enhances disease resistance to Ralstonia solanacearum in tobaccoQ34497339
The plant apoplasm is an important recipient compartment for nematode secreted proteins.Q34497916
Perception of the bacterial PAMP EF-Tu by the receptor EFR restricts Agrobacterium-mediated transformation.Q34528524
Chloroplastic protein NRIP1 mediates innate immune receptor recognition of a viral effector.Q34588234
RESISTANCE TO FUSARIUM OXYSPORUM 1, a dominant Arabidopsis disease-resistance gene, is not race specificQ34589065
A flagellin-induced complex of the receptor FLS2 and BAK1 initiates plant defenceQ34649229
MtQRRS1, an R-locus required for Medicago truncatula quantitative resistance to Ralstonia solanacearum.Q34703063
Identification of a functional nuclear localization signal mediating nuclear import of the zinc finger transcription factor ZNF24Q35041541
Plant cells recognize chitin fragments for defense signaling through a plasma membrane receptorQ35131204
Physical interaction between RRS1-R, a protein conferring resistance to bacterial wilt, and PopP2, a type III effector targeted to the plant nucleusQ35147632
The kinase LYK5 is a major chitin receptor in Arabidopsis and forms a chitin-induced complex with related kinase CERK1.Q35167012
The mRNA decay factor PAT1 functions in a pathway including MAP kinase 4 and immune receptor SUMM2.Q35192729
Expanded functions for a family of plant intracellular immune receptors beyond specific recognition of pathogen effectorsQ35239735
The phylogenetically-related pattern recognition receptors EFR and XA21 recruit similar immune signaling components in monocots and dicotsQ35546621
Recognition and Response in the Plant Immune SystemQ35583005
SRC2-1 is required in PcINF1-induced pepper immunity by acting as an interacting partner of PcINF1.Q35617268
Arabidopsis lysin-motif proteins LYM1 LYM3 CERK1 mediate bacterial peptidoglycan sensing and immunity to bacterial infectionQ35621165
The receptor-like kinase SERK3/BAK1 is a central regulator of innate immunity in plantsQ35901292
Evolutionary divergence of the plant elicitor peptides (Peps) and their receptors: interfamily incompatibility of perception but compatibility of downstream signallingQ35922271
Tomato Ve disease resistance genes encode cell surface-like receptorsQ35952096
Comparative analysis of NBS-LRR genes and their response to Aspergillus flavus in ArachisQ36269729
Regulation of tradeoffs between plant defenses against pathogens with different lifestylesQ36277057
The rice immune receptor XA21 recognizes a tyrosine-sulfated protein from a Gram-negative bacteriumQ36284778
CERK1, a LysM receptor kinase, is essential for chitin elicitor signaling in ArabidopsisQ36288751
A new eye on NLR proteins: focused on clarity or diffused by complexity?Q36351436
Protein-protein interactions in the RPS4/RRS1 immune receptor complexQ36364255
A catalogue of the effector secretome of plant pathogenic oomycetesQ36382600
Tête à tête inside a plant cell: establishing compatibility between plants and biotrophic fungi and oomycetesQ36570570
Pepper CabZIP63 acts as a positive regulator during Ralstonia solanacearum or high temperature-high humidity challenge in a positive feedback loop with CaWRKY40.Q36733454
NbCSPR underlies age-dependent immune responses to bacterial cold shock protein in Nicotiana benthamianaQ36742798
Avirulence proteins from haustoria-forming pathogens.Q36753744
N-terminal motifs in some plant disease resistance proteins function in membrane attachment and contribute to disease resistance.Q50508629
Plant microRNAs: Front line players against invading pathogens.Q51148425
Detection of the plant parasite Cuscuta reflexa by a tomato cell surface receptor.Q51607898
Symbiotic use of pathogenic strategies: rhizobial protein secretion systems.Q51777866
MAP kinase signalling cascade in Arabidopsis innate immunity.Q52594626
Deletion of the Phytophthora sojae avirulence gene Avr1d causes gain of virulence on Rps1d.Q52639709
Expression and functional evaluation of CaZNF830 during pepper response to Ralstonia solanacearum or high temperature and humidity.Q53698874
Arabidopsis RIN4 negatively regulates disease resistance mediated by RPS2 and RPM1 downstream or independent of the NDR1 signal modulator and is not required for the virulence functions of bacterial type III effectors AvrRpt2 or AvrRpm1.Q53885741
MAP kinase signalling: interplays between plant PAMP- and effector-triggered immunity.Q54107720
CaWRKY22 Acts as a Positive Regulator in Pepper Response to RalstoniaSolanacearum by Constituting Networks with CaWRKY6, CaWRKY27, CaWRKY40, and CaWRKY58.Q54215261
Molecular identification and characterization of the tomato flagellin receptor LeFLS2, an orthologue of Arabidopsis FLS2 exhibiting characteristically different perception specificities.Q54440734
The Arabidopsis receptor kinase FLS2 binds flg22 and determines the specificity of flagellin perception.Q55041494
CaWRKY40b in Pepper Acts as a Negative Regulator in Response to Ralstonia solanacearum by Directly Modulating Defense Genes Including CaWRKY40.Q55105373
From Guard to Decoy: a new model for perception of plant pathogen effectorsQ57441458
Quantitative Phosphoproteomics of Early Elicitor Signaling inArabidopsisQ57448564
Capsicum annuum HsfB2a positively regulates the response to Ralstonia solanacearum infection or high temperature and high humidity forming transcriptional cascade with CaWRKY6 and CaWRKY40Q59353496
Ultrastructure of the host-pathogen interface in daylily leaves infected by the rust fungus Puccinia hemerocallidisQ74415437
Cladosporium fulvum circumvents the second functional resistance gene homologue at the Cf-4 locus (Hcr9-4E ) by secretion of a stable avr4E isoformQ80832120
WRR4, a broad-spectrum TIR-NB-LRR gene from Arabidopsis thaliana that confers white rust resistance in transgenic oilseed Brassica cropsQ84169683
Front-runners in plant-microbe interactionsQ84573198
Genetic dissection of basal resistance to Pseudomonas syringae pv. phaseolicola in accessions of ArabidopsisQ84588490
HSP90s are required for NLR immune receptor accumulation in ArabidopsisQ88007597
Networks of WRKY transcription factors in defense signaling.Q36888216
LYM2-dependent chitin perception limits molecular flux via plasmodesmataQ36895663
RXLR effectors of plant pathogenic oomycetesQ36914017
Receptor-like kinase SOBIR1/EVR interacts with receptor-like proteins in plant immunity against fungal infectionQ36932197
Plant NB-LRR immune receptors: from recognition to transcriptional reprogrammingQ37105837
Plant pathogenic bacterial type III effectors subdue host responsesQ37121277
Oomycete RXLR effectors: delivery, functional redundancy and durable disease resistanceQ37176861
Flg22 regulates the release of an ethylene response factor substrate from MAP kinase 6 in Arabidopsis thaliana via ethylene signalingQ37194761
Recent Advances in Plant NLR Structure, Function, Localization, and SignalingQ37240816
Salicylic acid receptors activate jasmonic acid signalling through a non-canonical pathway to promote effector-triggered immunityQ37336222
The hijacking of a receptor kinase-driven pathway by a wheat fungal pathogen leads to diseaseQ37388044
Networking by small-molecule hormones in plant immunity.Q37450759
Salicylic Acid, a multifaceted hormone to combat disease.Q37462957
The role of WRKY transcription factors in plant immunityQ37472672
Chitin-induced activation of immune signaling by the rice receptor CEBiP relies on a unique sandwich-type dimerizationQ37519787
MAPK cascade signalling networks in plant defenceQ37553513
NB-LRR proteins: pairs, pieces, perception, partners, and pathwaysQ37756318
Activation of plant pattern-recognition receptors by bacteria.Q37826863
Endogenous peptide elicitors in higher plantsQ37884243
Protein kinase signaling networks in plant innate immunityQ37894375
Immune receptor complexes at the plant cell surfaceQ38212302
Effector-triggered immunity: from pathogen perception to robust defense.Q38286115
Functional characterization of CEBiP and CERK1 homologs in arabidopsis and rice reveals the presence of different chitin receptor systems in plantsQ38322671
Characterization of the tomato Cf-4 gene for resistance to Cladosporium fulvum identifies sequences that determine recognitional specificity in Cf-4 and Cf-9.Q38340779
P275copyright licenseCreative Commons AttributionQ6905323
P6216copyright statuscopyrightedQ50423863
P433issue8
P407language of work or nameEnglishQ1860
P921main subjectintracellular signaling peptides and proteinsQ67575047
P304page(s)1882
P577publication date2019-04-16
P1433published inInternational Journal of Molecular SciencesQ3153277
P1476titlePRRs and NB-LRRs: From Signal Perception to Activation of Plant Innate Immunity
P478volume20

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