scholarly article | Q13442814 |
P50 | author | Coen Maas | Q52872286 |
P2093 | author name string | Steven de Maat | |
Wariya Sanrattana | |||
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Extracellular export of sphingosine kinase-1 enzyme. Sphingosine 1-phosphate generation and the induction of angiogenic vascular maturation | Q40763807 | ||
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Antithrombin III Utilization in a Large Teaching Hospital | Q42771225 | ||
The serpin inhibitory mechanism is critically dependent on the length of the reactive center loop | Q43590670 | ||
Inhibition of HIV-1 gp160-dependent membrane fusion by a furin-directed alpha 1-antitrypsin variant | Q43912898 | ||
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The MEROPS database of proteolytic enzymes, their substrates and inhibitors in 2017 and a comparison with peptidases in the PANTHER database. | Q45995268 | ||
Physiologic inhibition of human activated protein C by alpha 1-antitrypsin | Q46689022 | ||
Manipulation of thrombin exosite I, by ligand-directed covalent modification | Q46990394 | ||
Familial thrombosis due to antithrombin 3 deficiency | Q47894264 | ||
Pathophysiology of Alpha-1 Antitrypsin Deficiency Liver Disease | Q48018051 | ||
N- and O-glycosylation analysis of human C1-inhibitor reveals extensive mucin-type O-glycosylation | Q49886884 | ||
A Phase I/II, Double-Blind, Placebo-Controlled Study Assessing Safety and Efficacy of C1 Esterase Inhibitor for Prevention of Delayed Graft Function in Deceased Donor Kidney Transplant Recipients. | Q52594635 | ||
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Dominant negative SERPING1 variants cause intracellular retention of C1-inhibitor in hereditary angioedema | Q58607420 | ||
Overview of Serpins and Their Roles in Biological Systems | Q59353093 | ||
Heparin modulation of human plasma kallikrein on different substrates and inhibitors | Q62065130 | ||
Reactivity of alpha 1-antitrypsin mutants against proteolytic enzymes of the kallikrein-kinin, complement, and fibrinolytic systems | Q68518085 | ||
Effect of heparin on the inactivation rate of human activated factor XII by antithrombin III | Q69869393 | ||
Serpin-protease complexes are trapped as stable acyl-enzyme intermediates | Q71823584 | ||
Mechanism of protein C deficiency in a patient with arginine 358 alpha 1-antitrypsin (Pittsburgh mutation): role in the maintenance of hemostatic balance | Q72133584 | ||
C1 esterase inhibitor concentrate for capillary leakage syndrome following bone marrow transplantation | Q73877807 | ||
Role of the P6-P3' region of the serpin reactive loop in the formation and breakdown of the inhibitory complex | Q73940199 | ||
Recombinant antitrypsin Pittsburgh undergoes proteolytic cleavage during E. coli sepsis and fails to prevent the associated coagulopathy in a primate model | Q77647776 | ||
Effects of C1 inhibitor on tissue damage in a porcine model of controlled hemorrhage | Q84344626 | ||
[Inter[retation of 2019 Global Strategy for the Diagnosis, Management and Prevention of chronic Obstructive Pulmonary Disease] | Q91164841 | ||
The effect of a single nucleotide polymorphism on human alpha 2-antiplasmin activity | Q24298078 | ||
Canonical inhibitor-like interactions explain reactivity of alpha1-proteinase inhibitor Pittsburgh and antithrombin with proteinases | Q24308401 | ||
An overview of the serpin superfamily | Q24684030 | ||
Topography of a 2.0 Å structure of α1-antitrypsin reveals targets for rational drug design to prevent conformational disease | Q27626230 | ||
The S variant of human alpha 1-antitrypsin, structure and implications for function and metabolism | Q27728485 | ||
On the size of the active site in proteases. I. Papain | Q27860826 | ||
Serpin structure, mechanism, and function | Q28217095 | ||
Human furin is a calcium-dependent serine endoprotease that recognizes the sequence Arg-X-X-Arg and efficiently cleaves anthrax toxin protective antigen | Q28610305 | ||
Synthesis of positional-scanning libraries of fluorogenic peptide substrates to define the extended substrate specificity of plasmin and thrombin | Q30836220 | ||
C1 esterase inhibitor reduces lower extremity ischemia/reperfusion injury and associated lung damage | Q31132259 | ||
Partitioning of serpin-proteinase reactions between stable inhibition and substrate cleavage is regulated by the rate of serpin reactive center loop insertion into beta-sheet A. | Q33179776 | ||
Phylogeny of the serpin superfamily: implications of patterns of amino acid conservation for structure and function. | Q33928073 | ||
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Effects of mutations in the hinge region of serpins | Q34352355 | ||
Recombinant alpha 1-antitrypsin Pittsburgh (Met 358----Arg) is a potent inhibitor of plasma kallikrein and activated factor XII fragment | Q34522312 | ||
Inherited antithrombin deficiency: a review | Q34920789 | ||
Protection by recombinant alpha 1-antitrypsin Ala357 Arg358 against arterial hypotension induced by factor XII fragment | Q35577711 | ||
Recombinant alpha 1-antitrypsin Pittsburgh attenuates experimental gram-negative septicemia | Q35818183 | ||
Design and characterization of an APC-specific serpin for the treatment of hemophilia. | Q36176667 | ||
alpha(1)-Proteinase inhibitor mutants with specificity for plasma kallikrein and C1s but not C1 | Q36639349 | ||
Serpins in thrombosis, hemostasis and fibrinolysis | Q36884340 | ||
Contribution of Plasma Protease Inhibitors to the Inactivation of Kallikrein in Plasma | Q37007907 | ||
Cinryze, a human plasma-derived c1 esterase inhibitor for prophylaxis of hereditary angioedema | Q37231222 | ||
Kinetic intermediates en route to the final serpin-protease complex: studies of complexes of α1-protease inhibitor with trypsin | Q37272213 | ||
Exosite determinants of serpin specificity | Q37343928 | ||
Mechanisms of emphysema in alpha1-antitrypsin deficiency: molecular and cellular insights | Q37569437 | ||
The plasma bradykinin-forming pathways and its interrelationships with complement | Q37767845 | ||
Molecular mechanisms of antithrombin-heparin regulation of blood clotting proteinases. A paradigm for understanding proteinase regulation by serpin family protein proteinase inhibitors. | Q37777806 | ||
P275 | copyright license | Creative Commons Attribution 4.0 International | Q20007257 |
P6216 | copyright status | copyrighted | Q50423863 |
P407 | language of work or name | English | Q1860 |
P304 | page(s) | 25 | |
P577 | publication date | 2019-02-12 | |
P1433 | published in | Frontiers in Medicine | Q27726181 |
P1476 | title | SERPINs-From Trap to Treatment | |
P478 | volume | 6 |
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