NF-κB-Associated Pain-Related Neuropeptide Expression in Patients with Degenerative Disc Disease

journal article from 'International Journal of Molecular Sciences' published in 2019

NF-κB-Associated Pain-Related Neuropeptide Expression in Patients with Degenerative Disc Disease is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.3390/IJMS20030658
P953full work available at URLhttps://www.mdpi.com/1422-0067/20/3/658
P932PMC publication ID6386867
P698PubMed publication ID30717434

P50authorCamilla I SvenssonQ59689137
P2093author name stringHenrik Druid
Kanar Alkass
David A Hart
Eva Kosek
David A. Hart
Camilla I. Svensson
Svante Berg
Aisha S Ahmed
Aisha S. Ahmed
P2860cites workExpression and regulation of neurotrophins in the nondegenerate and degenerate human intervertebral discQ22000853
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Matrix metalloproteinase expression levels suggest distinct enzyme roles during lumbar disc herniation and degenerationQ33972129
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Increase of TRPV1-immunoreactivity in dorsal root ganglia neurons innervating the femur in a rat model of osteoporosisQ34384378
Transcription factors Sp1 and Sp4 regulate TRPV1 gene expression in rat sensory neuronsQ35063692
Interplay of IKK/NF-kappaB signaling in macrophages and myofibers promotes muscle degeneration in Duchenne muscular dystrophyQ35677654
Signaling transduction: target in osteoarthritisQ35864727
Painful, degenerating intervertebral discs up-regulate neurite sprouting and CGRP through nociceptive factorsQ35867969
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Nuclear factor-kappa B regulates pain and COMT expression in a rodent model of inflammation.Q36244796
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Immunohistochemical observations on spinal tissue innervation: A review of hypothetical mechanisms of back painQ37122078
MicroRNA-9 regulates the development of knee osteoarthritis through the NF-kappaB1 pathway in chondrocytesQ37256802
The pathophysiology of disc degeneration: a critical reviewQ37283141
Increased expression of matrix metalloproteinase-10, nerve growth factor and substance P in the painful degenerate intervertebral disc.Q37350940
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Substance P enhances collagen remodeling and MMP-3 expression by human tenocytes.Q37646554
Mechanics and biology in intervertebral disc degeneration: a vicious circle.Q38398069
Substance P immunoreactivity increases following human traumatic brain injuryQ38418930
Regulation of calcitonin gene-related peptide and TRPV1 in a rat model of osteoarthritisQ39364082
Effects of nuclear factor kappa B signaling pathway in human intervertebral disc degenerationQ41706071
Changes in the Expressions of Iba1 and Calcitonin Gene-Related Peptide in Adjacent Lumbar Spinal Segments after Lumbar Disc Herniation in a Rat Model.Q42199577
Intrathecal infusion of pyrrolidine dithiocarbamate for the prevention and reversal of neuropathic pain in rats using a sciatic chronic constriction injury model.Q42870095
Attenuation of pain and inflammation in adjuvant-induced arthritis by the proteasome inhibitor MG132.Q43053216
The TRPV1 ion channel antagonist capsazepine inhibits osteoclast and osteoblast differentiation in vitro and ovariectomy induced bone loss in vivoQ43185550
IκB kinase β inhibitor downregulates pain-related neuropeptide production in the sensory neurons innervating injured lumbar intervertebral discs in the dorsal root ganglia of ratsQ43664336
Involvement of p38 and JNK MAPKs pathways in Substance P-induced production of TNF-alpha by peritoneal mast cellsQ44049735
Reactive oxygen species (ROS) play an important role in a rat model of neuropathic painQ45029206
Disc inflammation potentially promotes axonal regeneration of dorsal root ganglion neurons innervating lumbar intervertebral disc in ratsQ45163444
Antioxidant alpha-lipoic acid inhibits osteoclast differentiation by reducing nuclear factor-kappaB DNA binding and prevents in vivo bone resorption induced by receptor activator of nuclear factor-kappaB ligand and tumor necrosis factor-alphaQ48571985
The effect of curcumin on NF-κB expression in rat with lumbar intervertebral disc degeneration.Q53527163
TRPA1 and TRPV1 Antagonists Do Not Inhibit Human Acidosis-Induced Pain.Q54297938
Suppression of pain and joint destruction by inhibition of the proteasome system in experimental osteoarthritis.Q54342778
Matrix Metalloproteinases And AggrecanaseQ57539949
Proteasome inhibitor MG132 modulates inflammatory pain by central mechanisms in adjuvant arthritisQ57928721
Immunomorphological Analysis of RAGE Receptor Expression and NF- B Activation in Tissue Samples from Normal and Degenerated Intervertebral Discs of Various AgesQ63341139
The Oswestry low back pain disability questionnaireQ66829376
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Reported pain during lumbar discography as a function of anular ruptures and disc degeneration. A re-analysis of 833 discogramsQ72900735
Nerve ingrowth into diseased intervertebral disc in chronic back painQ73570649
Inhibition of NF-kappaB activity and enhancement of apoptosis by the neuropeptide calcitonin gene-related peptideQ73789344
NF-kappa B decoy suppresses cytokine expression and thermal hyperalgesia in a rat neuropathic pain modelQ74180794
Herniated and spondylotic intervertebral discs of the human cervical spine: histological and immunohistological findings in 500 en bloc surgical samples. Laboratory investigationQ79628312
The IkappaB kinase (IKK) inhibitor, NEMO-binding domain peptide, blocks osteoclastogenesis and bone erosion in inflammatory arthritisQ80337310
Expression of transient receptor potential vanilloid 1 (TRPV1) in synovial fibroblasts from patients with osteoarthritis and rheumatoid arthritisQ80461012
Stability of RNA isolated from human trabecular bone at post-mortem and surgeryQ81723846
Expression of ion channels of the TRP family in articular chondrocytes from osteoarthritic patients: changes between native and in vitro propagated chondrocytesQ82213748
TRPV1-related modulation of spinal neuronal activity and behavior in a rat model of osteoarthritic painQ82293771
Dexmedetomidine Relieves Acute Inflammatory Visceral Pain in Rats through the ERK Pathway, Toll-Like Receptor Signaling, and TRPV1 ChannelQ91796524
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue3
P407language of work or nameEnglishQ1860
P921main subjectNF-κBQ411114
degenerative disc diseaseQ11773731
Chronic Low Back PainQ57839301
P304page(s)658
P577publication date2019-01-01
2019-02-03
P1433published inInternational Journal of Molecular SciencesQ3153277
P1476titleNF-κB-Associated Pain-Related Neuropeptide Expression in Patients with Degenerative Disc Disease
P478volume20

Reverse relations

Q90350368Alpha-lipoic acid downregulates TRPV1 receptor via NF-κB and attenuates neuropathic pain in rats with diabetescites workP2860

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