Exploring the xylose paradox in Saccharomyces cerevisiae through in vivo sugar signalomics of targeted deletants

scientific article published on 23 May 2019

Exploring the xylose paradox in Saccharomyces cerevisiae through in vivo sugar signalomics of targeted deletants is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1186/S12934-019-1141-X
P932PMC publication ID6532234
P698PubMed publication ID31122246

P50authorMarie Gorwa-GrauslundQ46732274
P2093author name stringCelina Borgström
Daniel P Brink
Karen O Osiro
Birta Líf Fjölnisdóttir
P2860cites workAnaerobic xylose fermentation by recombinant Saccharomyces cerevisiae carrying XYL1, XYL2, and XKS1 in mineral medium chemostat culturesQ24550509
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The yeast scaffold proteins Isu1p and Isu2p are required inside mitochondria for maturation of cytosolic Fe/S proteinsQ27937038
Genetic and epigenetic regulation of the FLO gene family generates cell-surface variation in yeastQ27937126
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A Saccharomyces cerevisiae G-protein coupled receptor, Gpr1, is specifically required for glucose activation of the cAMP pathway during the transition to growth on glucoseQ27938758
Unraveling the genetic basis of xylose consumption in engineered Saccharomyces cerevisiae strainsQ28585534
Engineering of an endogenous hexose transporter into a specific D-xylose transporter facilitates glucose-xylose co-consumption in Saccharomyces cerevisiaeQ28649983
Dynamic metabolomics differentiates between carbon and energy starvation in recombinant Saccharomyces cerevisiae fermenting xyloseQ28727366
Pichia stipitis xylose reductase helps detoxifying lignocellulosic hydrolysate by reducing 5-hydroxymethyl-furfural (HMF)Q28757699
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Limitations in Xylose-FermentingSaccharomyces cerevisiae, Made Evident through Comprehensive Metabolite Profiling and Thermodynamic AnalysisQ30475607
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Isolation and characterization of the Pichia stipitis xylitol dehydrogenase gene, XYL2, and construction of a xylose-utilizing Saccharomyces cerevisiae transformantQ33806229
Whole-Genome Sequence and Variant Analysis of W303, a Widely-Used Strain of Saccharomyces cerevisiaeQ33877330
Yeast PKA represses Msn2p/Msn4p-dependent gene expression to regulate growth, stress response and glycogen accumulationQ33889012
Transcription analysis of recombinant saccharomyces cerevisiae reveals novel responses to xylose.Q51220334
The repressor Rgt1 and the cAMP-dependent protein kinases control the expression of the SUC2 gene in Saccharomyces cerevisiae.Q52658448
To divide or not to divide: a key role of Rim15 in calorie-restricted yeast cultures.Q53068463
Xylose isomerase overexpression along with engineering of the pentose phosphate pathway and evolutionary engineering enable rapid xylose utilization and ethanol production by Saccharomyces cerevisiae.Q54488420
Two Glucose-sensing Pathways Converge on Rgt1 to Regulate Expression of Glucose Transporter Genes inSaccharomyces cerevisiaeQ57577864
Effect of benzoic acid on metabolic fluxes in yeasts: a continuous-culture study on the regulation of respiration and alcoholic fermentationQ68043176
Deletion of the GRE3 aldose reductase gene and its influence on xylose metabolism in recombinant strains of Saccharomyces cerevisiae expressing the xylA and XKS1 genesQ33990897
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Optimal growth and ethanol production from xylose by recombinant Saccharomyces cerevisiae require moderate D-xylulokinase activityQ34879081
Glucose-sensing and -signalling mechanisms in yeast.Q35110176
The yeast A kinases differentially regulate iron uptake and respiratory function.Q35756462
Transposon mutagenesis to improve the growth of recombinant Saccharomyces cerevisiae on D-xyloseQ35759290
Function and regulation in MAPK signaling pathways: lessons learned from the yeast Saccharomyces cerevisiaeQ36076499
Directed Evolution Reveals Unexpected Epistatic Interactions That Alter Metabolic Regulation and Enable Anaerobic Xylose Use by Saccharomyces cerevisiae.Q36163710
Real-time monitoring of the sugar sensing in Saccharomyces cerevisiae indicates endogenous mechanisms for xylose signalingQ36173457
An engineered cryptic Hxt11 sugar transporter facilitates glucose-xylose co-consumption in Saccharomyces cerevisiaeQ36242952
Evolved hexose transporter enhances xylose uptake and glucose/xylose co-utilization in Saccharomyces cerevisiae.Q36499949
Towards industrial pentose-fermenting yeast strainsQ36733733
Glucose-stimulated cAMP-protein kinase A pathway in yeast Saccharomyces cerevisiaeQ37006766
Engineering of yeast hexose transporters to transport D-xylose without inhibition by D-glucose.Q37702054
Advances and developments in strategies to improve strains of Saccharomyces cerevisiae and processes to obtain the lignocellulosic ethanol--a review.Q37990734
Molecular mechanisms of feedback inhibition of protein kinase A on intracellular cAMP accumulation.Q38004349
Metabolic engineering of industrial platform microorganisms for biorefinery applications--optimization of substrate spectrum and process robustness by rational and evolutive strategiesQ38069269
Kinase activity-dependent nuclear export opposes stress-induced nuclear accumulation and retention of Hog1 mitogen-activated protein kinase in the budding yeast Saccharomyces cerevisiaeQ38610444
Saccharomyces cerevisiae engineered for xylose metabolism exhibits a respiratory responseQ40283636
DMSO-enhanced whole cell yeast transformationQ40508044
De novo sequencing, assembly and analysis of the genome of the laboratory strain Saccharomyces cerevisiae CEN.PK113-7D, a model for modern industrial biotechnologyQ41821972
Increased expression of the oxidative pentose phosphate pathway and gluconeogenesis in anaerobically growing xylose-utilizing Saccharomyces cerevisiaeQ42035332
Competition between pentoses and glucose during uptake and catabolism in recombinant Saccharomyces cerevisiaeQ42182314
Anaerobic poly-3-D-hydroxybutyrate production from xylose in recombinant Saccharomyces cerevisiae using a NADH-dependent acetoacetyl-CoA reductase.Q42365699
A mutation in Saccharomyces cerevisiae adenylate cyclase, Cyr1K1876M, specifically affects glucose- and acidification-induced cAMP signalling and not the basal cAMP level.Q42475033
amdSYM, a new dominant recyclable marker cassette for Saccharomyces cerevisiaeQ43146673
Fermentation performance and intracellular metabolite patterns in laboratory and industrial xylose-fermenting Saccharomyces cerevisiaeQ44097840
High-level functional expression of a fungal xylose isomerase: the key to efficient ethanolic fermentation of xylose by Saccharomyces cerevisiae?Q44614650
Endogenous NADPH-dependent aldose reductase activity influences product formation during xylose consumption in recombinant Saccharomyces cerevisiae.Q44750822
Expression of the HXT1 low affinity glucose transporter requires the coordinated activities of the HOG and glucose signalling pathwaysQ44795463
Reactive oxygen species production induced by ethanol in Saccharomyces cerevisiae increases because of a dysfunctional mitochondrial iron-sulfur cluster assembly systemQ45163352
Metabolic engineering of a xylose-isomerase-expressing Saccharomyces cerevisiae strain for rapid anaerobic xylose fermentationQ45251239
Xylitol does not inhibit xylose fermentation by engineered Saccharomyces cerevisiae expressing xylA as severely as it inhibits xylose isomerase reaction in vitroQ45395158
Colony PCR.Q46266363
Deleting the para-nitrophenyl phosphatase (pNPPase), PHO13, in recombinant Saccharomyces cerevisiae improves growth and ethanol production on D-xyloseQ46771929
Assessing the effect of d-xylose on the sugar signaling pathways of Saccharomyces cerevisiae in strains engineered for xylose transport and assimilationQ47190114
Different signalling pathways mediate glucose induction of SUC2, HXT1 and pyruvate decarboxylase in yeast.Q51063409
Inhibition of G1 cyclin activity by the Ras/cAMP pathway in yeast.Q51131233
P433issue1
P407language of work or nameEnglishQ1860
P921main subjectSaccharomyces cerevisiaeQ719725
bioengineeringQ580689
biotechnologyQ7108
P304page(s)88
P577publication date2019-05-23
P1433published inMicrobial Cell FactoriesQ15766995
P1476titleExploring the xylose paradox in Saccharomyces cerevisiae through in vivo sugar signalomics of targeted deletants
P478volume18

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cites work (P2860)
Q92637418Simulating Extracellular Glucose Signals Enhances Xylose Metabolism in Recombinant Saccharomyces cerevisiae
Q92644514Structure-based directed evolution improves S. cerevisiae growth on xylose by influencing in vivo enzyme performance
Q90244604Xylose utilization stimulates mitochondrial production of isobutanol and 2-methyl-1-butanol in Saccharomyces cerevisiae