Establishment of a new murine model of hypercalcemia with anorexia by overexpression of soluble receptor activator of NF-κB ligand using an adenovirus vector

scientific article published on 10 November 2010

Establishment of a new murine model of hypercalcemia with anorexia by overexpression of soluble receptor activator of NF-κB ligand using an adenovirus vector is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1007/S00774-010-0235-7
P698PubMed publication ID21063739

P50authorJun-ichi MiyazakiQ55233932
P2093author name stringKaoru Mori
Hisataka Yasuda
Yuriko Furuya
Yoshiya Tomimori
Tetsuro Enomoto
P2860cites workOsteoprotegerin ligand is a cytokine that regulates osteoclast differentiation and activationQ24311588
Central control of fever and female body temperature by RANKL/RANKQ24321735
A homologue of the TNF receptor and its ligand enhance T-cell growth and dendritic-cell functionQ24336057
Tumor necrosis factor receptor family member RANK mediates osteoclast differentiation and activation induced by osteoprotegerin ligandQ24653311
Osteoclast differentiation factor is a ligand for osteoprotegerin/osteoclastogenesis-inhibitory factor and is identical to TRANCE/RANKLQ24682139
Efficient selection for high-expression transfectants with a novel eukaryotic vectorQ27860810
RANK is the essential signaling receptor for osteoclast differentiation factor in osteoclastogenesisQ28293009
Treatment of malignancy-associated hypercalcemia and cachexia with humanized anti-parathyroid hormone-related protein antibodyQ35581843
Evidence for the involvement of interleukin 6 in experimental cancer cachexiaQ35602921
The high rate of bone resorption in multiple myeloma is due to RANK (receptor activator of nuclear factor-kappaB) and RANK Ligand expressionQ35883830
Current management strategies for hypercalcemiaQ36168196
Medical treatment of malignancy-associated hypercalcemiaQ37090051
Parathyroid hormone-related protein in hypercalcaemia of malignancy.Q38773936
Transgenic mice overexpressing soluble osteoclast differentiation factor (sODF) exhibit severe osteoporosisQ39124107
Constructing adenoviral vectors by using the circular form of the adenoviral genome cloned in a cosmid and the Cre-loxP recombination systemQ40935563
A chimeric form of osteoprotegerin inhibits hypercalcemia and bone resorption induced by IL-1beta, TNF-alpha, PTH, PTHrP, and 1, 25(OH)2D3.Q41687961
Osteoprotegerin prevents and reverses hypercalcemia in a murine model of humoral hypercalcemia of malignancy.Q41723472
Role of bone and kidney in parathyroid hormone-related peptide-induced hypercalcemia in ratsQ44773041
Parathyroid hormone-related protein (PTHrP) as a causative factor of cancer-associated wasting: possible involvement of PTHrP in the repression of locomotor activity in rats bearing human tumor xenograftsQ46413191
Tyrosine kinases Btk and Tec regulate osteoclast differentiation by linking RANK and ITAM signals.Q46711436
Soluble RANKL induces high bone turnover and decreases bone volume, density, and strength in mice.Q51703171
Evaluation of pharmaceuticals with a novel 50-hour animal model of bone loss.Q51788770
Precision and accuracy of peripheral quantitative computed tomography (pQCT) in the mouse skeleton compared with histology and microcomputed tomography (microCT).Q53644083
Parathyroid hormone-related protein: elevated levels in both humoral hypercalcemia of malignancy and hypercalcemia complicating metastatic breast cancerQ68063865
Mechanisms of paraneoplastic syndromes of colon-26: involvement of interleukin 6 in hypercalcemiaQ72327484
Breast cancer cells interact with osteoblasts to support osteoclast formationQ73025244
Effects of YM175, a new-generation bisphosphonate, on hypercalcemia induced by tumor-derived bone resorbing factors in ratsQ74441299
HypercalcemiaQ79836751
Skeletal deterioration induced by RANKL infusion: a model for high-turnover bone diseaseQ79984770
P433issue4
P407language of work or nameEnglishQ1860
P921main subjectNF-κBQ411114
AdenoviridaeQ193447
murine modelQ122890741
P304page(s)414-421
P577publication date2010-11-10
P1433published inJournal of Bone and Mineral MetabolismQ15767236
P1476titleEstablishment of a new murine model of hypercalcemia with anorexia by overexpression of soluble receptor activator of NF-κB ligand using an adenovirus vector
P478volume29

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cites work (P2860)
Q64993249RANKL Reduces Body Weight and Food Intake via the Modulation of Hypothalamic NPY/CART Expression.
Q37241264RANKL, a necessary chance for clinical application to osteoporosis and cancer-related bone diseases
Q52836861The effects of P-gp and CYP450 modulated by rifampicin on the steroid-induced osteonecrosis of the femoral head.
Q34583769Vitamin D(3) at 50x AI attenuates the decline in paw grip endurance, but not disease outcomes, in the G93A mouse model of ALS, and is toxic in females

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