| scholarly article | Q13442814 |
| P2093 | author name string | Melike Çağlayan | |
| P2860 | cites work | Structural and mechanistic conservation in DNA ligases | Q22065999 |
| Characterization of the XRCC1-DNA ligase III complex in vitro and its absence from mutant hamster cells | Q24313256 | ||
| Activity of DNA ligase IV stimulated by complex formation with XRCC4 protein in mammalian cells | Q24320116 | ||
| The DNA ligase III zinc finger stimulates binding to DNA secondary structure and promotes end joining | Q24523839 | ||
| Second pathway for completion of human DNA base excision-repair: reconstitution with purified proteins and requirement for DNase IV (FEN1). | Q24532243 | ||
| DNA binding of Xrcc4 protein is associated with V(D)J recombination but not with stimulation of DNA ligase IV activity | Q24534080 | ||
| Targeting abnormal DNA repair in therapy-resistant breast cancers | Q24605455 | ||
| Kinetic mechanism of human DNA ligase I reveals magnesium-dependent changes in the rate-limiting step that compromise ligation efficiency | Q24605476 | ||
| An interaction between the mammalian DNA repair protein XRCC1 and DNA ligase III | Q24615666 | ||
| Eukaryotic DNA ligases: structural and functional insights | Q24617266 | ||
| Up-regulation of WRN and DNA ligase IIIalpha in chronic myeloid leukemia: consequences for the repair of DNA double-strand breaks | Q24619366 | ||
| Human DNA ligase III recognizes DNA ends by dynamic switching between two DNA-bound states | Q24631008 | ||
| An interaction between DNA ligase I and proliferating cell nuclear antigen: implications for Okazaki fragment synthesis and joining | Q24642184 | ||
| Rational design of human DNA ligase inhibitors that target cellular DNA replication and repair | Q24645423 | ||
| Coordination of steps in single-nucleotide base excision repair mediated by apurinic/apyrimidinic endonuclease 1 and DNA polymerase beta | Q24647277 | ||
| Molecular mechanism of DNA deadenylation by the neurological disease protein aprataxin | Q24651265 | ||
| Defective DNA ligation during short-patch single-strand break repair in ataxia oculomotor apraxia 1 | Q24651990 | ||
| Physical and functional interaction between DNA ligase IIIalpha and poly(ADP-Ribose) polymerase 1 in DNA single-strand break repair | Q24679360 | ||
| Sources of DNA double-strand breaks and models of recombinational DNA repair | Q27005814 | ||
| Structure of the adenylation domain of an NAD+-dependent DNA ligase | Q27618601 | ||
| DNA-bound structures and mutants reveal abasic DNA binding by APE1 and DNA repair coordination [corrected] | Q27621279 | ||
| MTH1 inhibition eradicates cancer by preventing sanitation of the dNTP pool | Q27643976 | ||
| Sustained active site rigidity during synthesis by human DNA polymerase μ | Q27681565 | ||
| Stereospecific targeting of MTH1 by (S)-crizotinib as an anticancer strategy | Q27682798 | ||
| Role of polymerase β in complementing aprataxin deficiency during abasic-site base excision repair | Q27690118 | ||
| Potent and Selective Inhibitors of MTH1 Probe Its Role in Cancer Cell Survival | Q27704032 | ||
| Pol μ dGTP mismatch insertion opposite T coupled with ligation reveals promutagenic DNA repair intermediate | Q57476547 | ||
| Mutant FUS causes DNA ligation defects to inhibit oxidative damage repair in Amyotrophic Lateral Sclerosis | Q58751835 | ||
| Eradication of LIG4-deficient glioblastoma cells by the combination of PARP inhibitor and alkylating agent | Q60910649 | ||
| The role of DNA single- and double-strand breaks in cell killing by ionizing radiation | Q64389026 | ||
| Mammalian DNA ligases. Serological evidence for two separate enzymes | Q67340332 | ||
| Analysis of the formation of AMP-DNA intermediate and the successive reaction by human DNA ligases I and II | Q68101168 | ||
| Ezymatic breakage and joining of deoxyribonucleic acid. VII. Properties of the enzyme-adenylate intermediate in the polynucleotide ligase reaction | Q69854820 | ||
| Reconstitution of the DNA base excision-repair pathway | Q71686159 | ||
| Passing the baton in base excision repair | Q73505096 | ||
| Human DNA polymerase beta deoxyribose phosphate lyase. Substrate specificity and catalytic mechanism | Q74615796 | ||
| The type of DNA glycosylase determines the base excision repair pathway in mammalian cells | Q77754917 | ||
| Functional domains of an ATP-dependent DNA ligase | Q77760324 | ||
| APE1: A skilled nucleic acid surgeon | Q91253133 | ||
| Ribonucleotide incorporation enables repair of chromosome breaks by nonhomologous end joining | Q91436037 | ||
| Efficiency of correct nucleotide insertion governs DNA polymerase fidelity. | Q38362195 | ||
| Time-lapse crystallography snapshots of a double-strand break repair polymerase in action | Q38399920 | ||
| A chemical and kinetic perspective on base excision repair of DNA. | Q38862585 | ||
| Pathways controlling dNTP pools to maintain genome stability | Q38867301 | ||
| An inhibitor of nonhomologous end-joining abrogates double-strand break repair and impedes cancer progression | Q39222368 | ||
| XRCC1 polypeptide interacts with DNA polymerase beta and possibly poly (ADP-ribose) polymerase, and DNA ligase III is a novel molecular 'nick-sensor' in vitro | Q39718210 | ||
| Delayed DNA joining at 3' mismatches by human DNA ligases | Q39729273 | ||
| Kinetic characterization of single strand break ligation in duplex DNA by T4 DNA ligase. | Q39936281 | ||
| DNA ligase I mediates essential functions in mammalian cells | Q40016859 | ||
| Exchangeability of mammalian DNA ligases between base excision repair pathways | Q40508647 | ||
| Mammalian DNA ligases | Q41639282 | ||
| Dual mode of inhibition of purified DNA ligase I from human cells by 9-beta-D-arabinofuranosyl-2-fluoroadenine triphosphate | Q41640354 | ||
| Base excision repair enzyme family portrait: integrating the structure and chemistry of an entire DNA repair pathway. | Q41687087 | ||
| DNA Ligase IV Guides End-Processing Choice during Nonhomologous End Joining | Q42380664 | ||
| The fidelity of the ligation step determines how ends are resolved during nonhomologous end joining. | Q42744119 | ||
| DNA ligase I and proliferating cell nuclear antigen form a functional complex | Q43594136 | ||
| Purification and characterization of DNA ligase III from bovine testes. Homology with DNA ligase II and vaccinia DNA ligase | Q44361047 | ||
| A conserved interaction between the replicative clamp loader and DNA ligase in eukaryotes: implications for Okazaki fragment joining | Q45122208 | ||
| DNA polymerase beta and flap endonuclease 1 enzymatic specificities sustain DNA synthesis for long patch base excision repair | Q45345086 | ||
| Role of DNA polymerase β oxidized nucleotide insertion in DNA ligation failure. | Q46290686 | ||
| DNA polymerase beta participates in DNA End-joining. | Q47378572 | ||
| Determination of the free-energy change for repair of a DNA phosphodiester bond | Q47621293 | ||
| Mammalian abasic site base excision repair. Identification of the reaction sequence and rate-determining steps | Q47724136 | ||
| Structure-activity relationships among DNA ligase inhibitors: Characterization of a selective uncompetitive DNA ligase I inhibitor | Q47872719 | ||
| Kinetic analyses of single-stranded break repair by human DNA ligase III isoforms reveal biochemical differences from DNA ligase I. | Q48019352 | ||
| Dynamic basis for dG•dT misincorporation via tautomerization and ionization. | Q50114971 | ||
| Repair of DNA double-strand breaks by mammalian alternative end-joining pathways. | Q52659674 | ||
| DNA ligase--a means to an end joining. | Q53489164 | ||
| Inhibition of human DNA ligase I activity by zinc and cadmium and the fidelity of ligation. | Q55066555 | ||
| Structures of DNA-bound human ligase IV catalytic core reveal insights into substrate binding and catalysis. | Q55473320 | ||
| XRCC4:DNA ligase IV can ligate incompatible DNA ends and can ligate across gaps | Q27919707 | ||
| Oxidant and environmental toxicant-induced effects compromise DNA ligation during base excision DNA repair | Q28088379 | ||
| Interactions of the DNA ligase IV-XRCC4 complex with DNA ends and the DNA-dependent protein kinase | Q28138342 | ||
| DNA double-strand breaks: signaling, repair and the cancer connection | Q28204231 | ||
| Activities and mechanism of DNA polymerase beta | Q28247869 | ||
| Repair of double-strand DNA breaks by the human nonhomologous DNA end joining pathway: the iterative processing model | Q28265941 | ||
| Human DNA ligase I completely encircles and partially unwinds nicked DNA | Q28295280 | ||
| DNA ligase I null mouse cells show normal DNA repair activity but altered DNA replication and reduced genome stability | Q28513276 | ||
| Interaction between PCNA and DNA ligase I is critical for joining of Okazaki fragments and long-patch base-excision repair | Q28645603 | ||
| Specific interaction of DNA polymerase beta and DNA ligase I in a multiprotein base excision repair complex from bovine testis | Q28645719 | ||
| Thermodynamics of human DNA ligase I trimerization and association with DNA polymerase beta | Q28645732 | ||
| Biochemical and Structural Characterisation of DNA Ligases from Bacteria and Archaea | Q28822439 | ||
| Single-strand break repair and genetic disease | Q29615347 | ||
| Oxidative stress, inflammation, and cancer: how are they linked? | Q29616835 | ||
| Differential recruitment of DNA Ligase I and III to DNA repair sites | Q33251083 | ||
| Nonhomologous end joining: a good solution for bad ends | Q33625010 | ||
| DNA ligase I is recruited to sites of DNA replication by an interaction with proliferating cell nuclear antigen: identification of a common targeting mechanism for the assembly of replication factories | Q33889077 | ||
| Base excision repair of DNA in mammalian cells | Q33957142 | ||
| DNA ligases in the repair and replication of DNA. | Q34006361 | ||
| Targeting DNA repair pathways for cancer treatment: what's new? | Q34015040 | ||
| DNA ligases: progress and prospects | Q34016787 | ||
| Pol β associated complex and base excision repair factors in mouse fibroblasts. | Q34033880 | ||
| Elevated expression of DNA ligase I in human cancers | Q34105863 | ||
| DNA ligase: structure, mechanism, and function | Q34208221 | ||
| Targeting abnormal DNA double-strand break repair in tyrosine kinase inhibitor-resistant chronic myeloid leukemias | Q34277769 | ||
| XRCC4 and XLF form long helical protein filaments suitable for DNA end protection and alignment to facilitate DNA double strand break repair | Q34329896 | ||
| Keynote: past, present, and future aspects of base excision repair | Q34367323 | ||
| Structure and function of the DNA ligases encoded by the mammalian LIG3 gene | Q34369324 | ||
| DNA ligases as therapeutic targets | Q34384677 | ||
| Substrate channeling in mammalian base excision repair pathways: passing the baton | Q34412541 | ||
| Involvement of XRCC1 and DNA ligase III gene products in DNA base excision repair. | Q34439025 | ||
| Cells expressing FLT3/ITD mutations exhibit elevated repair errors generated through alternative NHEJ pathways: implications for genomic instability and therapy | Q34450478 | ||
| Mutagenesis and carcinogenesis caused by the oxidation of nucleic acids. | Q34512398 | ||
| Validation and development of MTH1 inhibitors for treatment of cancer. | Q34544355 | ||
| Novel Class of Potent and Cellularly Active Inhibitors Devalidates MTH1 as Broad-Spectrum Cancer Target | Q34558489 | ||
| Recognition and repair of chemically heterogeneous structures at DNA ends | Q35002075 | ||
| Dynamic mechanism of nick recognition by DNA ligase | Q35020959 | ||
| Oxidative nucleotide damage: consequences and prevention | Q35026366 | ||
| Mutagenic potentials of damaged nucleic acids produced by reactive oxygen/nitrogen species: approaches using synthetic oligonucleotides and nucleotides: survey and summary | Q35044983 | ||
| Complementation of aprataxin deficiency by base excision repair enzymes. | Q35131143 | ||
| XRCC1 and DNA strand break repair | Q35216366 | ||
| A review of recent experiments on step-to-step "hand-off" of the DNA intermediates in mammalian base excision repair pathways. | Q35282710 | ||
| Repair of abasic sites in DNA. | Q35592868 | ||
| Mammalian DNA ligases | Q35671025 | ||
| Quantitative characterization of protein-protein complexes involved in base excision DNA repair | Q35842555 | ||
| Oxidative DNA damage and disease: induction, repair and significance | Q35876708 | ||
| Human DNA ligase III bridges two DNA ends to promote specific intermolecular DNA end joining | Q35961937 | ||
| DNA ligase: getting a grip to seal the deal. | Q36032009 | ||
| DNA ligases: structure, reaction mechanism, and function | Q36389679 | ||
| MTH1, an oxidized purine nucleoside triphosphatase, prevents the cytotoxicity and neurotoxicity of oxidized purine nucleotides | Q36452343 | ||
| Ligase I and ligase III mediate the DNA double-strand break ligation in alternative end-joining | Q36563447 | ||
| Continuous elimination of oxidized nucleotides is necessary to prevent rapid onset of cellular senescence | Q37068403 | ||
| Location of the active site for enzyme-adenylate formation in DNA ligases | Q37369817 | ||
| Identification and validation of human DNA ligase inhibitors using computer-aided drug design | Q37459758 | ||
| Human apurinic/apyrimidinic endonuclease 1. | Q37512952 | ||
| Oxidized nucleotide insertion by pol β confounds ligation during base excision repair | Q37581618 | ||
| Futile short-patch DNA base excision repair of adenine:8-oxoguanine mispair | Q37619499 | ||
| Programmed cell death triggered by nucleotide pool damage and its prevention by MutT homolog-1 (MTH1) with oxidized purine nucleoside triphosphatase | Q37764544 | ||
| Oxidized purine nucleotides, genome instability and neurodegeneration | Q37769935 | ||
| Oxidation in the nucleotide pool, the DNA damage response and cellular senescence: Defective bricks build a defective house | Q37776792 | ||
| Redox control of the survival of healthy and diseased cells | Q37860340 | ||
| DNA ligase I, the replicative DNA ligase | Q38037375 | ||
| Human DNA ligases: a comprehensive new look for cancer therapy | Q38130159 | ||
| Modernizing the nonhomologous end-joining repertoire: alternative and classical NHEJ share the stage. | Q38139497 | ||
| Apurinic and Apyrimidinic Sites in DNA | Q38162655 | ||
| Vaccinia virus DNA ligase: specificity, fidelity, and inhibition | Q38288073 | ||
| The mutagenic potential of non-homologous end joining in the absence of the NHEJ core factors Ku70/80, DNA-PKcs and XRCC4-LigIV. | Q38303919 | ||
| Role of the DNA ligase III zinc finger in polynucleotide binding and ligation. | Q38332424 | ||
| Kinetics and thermodynamics of nick sealing by T4 DNA ligase | Q38347969 | ||
| P433 | issue | 11 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | DNA polymerase | Q206286 |
| DNA ligase | Q408483 | ||
| P304 | page(s) | 2068-2081 | |
| P577 | publication date | 2019-04-26 | |
| P1433 | published in | Journal of Molecular Biology | Q925779 |
| P1476 | title | Interplay between DNA Polymerases and DNA Ligases: Influence on Substrate Channeling and the Fidelity of DNA Ligation | |
| P478 | volume | 431 |
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