Mutational and transcriptional landscape of spontaneous gene duplications and deletions in Caenorhabditis elegans.

scientific article

Mutational and transcriptional landscape of spontaneous gene duplications and deletions in Caenorhabditis elegans. is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1073/PNAS.1801930115
P932PMC publication ID6048555
P698PubMed publication ID29941601

P50authorAnke KonradQ53105811
Donald G MoermanQ84913499
Stephane FlibotteQ84914570
P2093author name stringRobert H Waterston
Vaishali Katju
Ulfar Bergthorsson
Jon Taylor
P2860cites workBias in the introduction of variation as an orienting factor in evolutionQ22121944
Fundamental concepts in genetics: Effective population size and patterns of molecular evolution and variationQ22122006
Massive genomic rearrangement acquired in a single catastrophic event during cancer developmentQ24631164
Genome sequence of the nematode C. elegans: a platform for investigating biologyQ27860527
Multicopy suppression underpins metabolic evolvabilityQ28249970
The genomic signature of dog domestication reveals adaptation to a starch-rich dietQ28284286
In with the old, in with the new: the promiscuity of the duplication process engenders diverse pathways for novel gene creationQ28727624
The population genetics of structural variationQ28752151
Recombinational landscape and population genomics of Caenorhabditis elegansQ33417666
Copy number variation in the genomes of twelve natural isolates of Caenorhabditis elegansQ33526497
Tandem duplications lead to novel expression patterns through exon shuffling in Drosophila yakubaQ33769279
Duplication frequency in a population of Salmonella enterica rapidly approaches steady state with or without recombinationQ33834935
On the theory of partially inbreeding finite populations. I. Partial selfingQ33953457
Maintenance of duplicate genes and their functional redundancy by reduced expressionQ34131177
Dosage sensitivity and the evolution of gene families in yeastQ34213245
The structure and early evolution of recently arisen gene duplicates in the Caenorhabditis elegans genome.Q34619212
High spontaneous rate of gene duplication in Caenorhabditis elegansQ34667651
The million mutation project: a new approach to genetics in Caenorhabditis elegansQ34783904
Intra-genomic variation in the ribosomal repeats of nematodesQ35023564
Rapid Increase in frequency of gene copy-number variants during experimental evolution in Caenorhabditis elegansQ35863160
The ace-1 Locus Is Amplified in All Resistant Anopheles gambiae Mosquitoes: Fitness Consequences of Homogeneous and Heterogeneous DuplicationsQ36213380
Gene balance hypothesis: connecting issues of dosage sensitivity across biological disciplinesQ36236350
Genomic variation in natural populations of Drosophila melanogasterQ36268123
High mutational rates of large-scale duplication and deletion in Daphnia pulex.Q36406085
Chromoanasynthetic Genomic Rearrangement Identified in a N-Ethyl-N-Nitrosourea (ENU) Mutagenesis Screen in Caenorhabditis elegansQ36574545
Population Structure Shapes Copy Number Variation in Malaria ParasitesQ36596835
A genome-wide view of the spectrum of spontaneous mutations in yeast.Q36756806
Expression of tandem gene duplicates is often greater than twofoldQ36957413
Evidence for the fixation of gene duplications by positive selection in Drosophila.Q36959142
Rates and genomic consequences of spontaneous mutational events in Drosophila melanogasterQ37063145
Copy-number changes in evolution: rates, fitness effects and adaptive significanceQ37379672
Pan-cancer patterns of somatic copy number alterationQ37666205
The evolution of duplicate gene expression in mammalian organsQ38661582
Efficient high-resolution deletion discovery in Caenorhabditis elegans by array comparative genomic hybridizationQ42108619
Gene dosage balance in cellular pathways: implications for dominance and gene duplicabilityQ42921721
Mitochondrial Mutation Rate, Spectrum and Heteroplasmy in Caenorhabditis elegans Spontaneous Mutation Accumulation Lines of Differing Population SizeQ47243402
Recurrent gene amplification and soft selective sweeps during evolution of multidrug resistance in malaria parasitesQ48036854
Segmental copy number variation shapes tissue transcriptomes.Q48712677
High fitness costs and instability of gene duplications reduce rates of evolution of new genes by duplication-divergence mechanisms.Q51100202
Natural selection shapes genome-wide patterns of copy-number polymorphism in Drosophila melanogaster.Q51686575
Fitness decline under osmotic stress in Caenorhabditis elegans populations subjected to spontaneous mutation accumulation at varying population sizes.Q52669658
Fixation probability of a mutant influenced by random fluctuation of selection intensityQ70369861
Fitness decline in spontaneous mutation accumulation lines of Caenorhabditis elegans with varying effective population sizesQ85843641
P433issue28
P921main subjectCaenorhabditis elegansQ91703
gene duplicationQ746284
P304page(s)7386-7391
P577publication date2018-06-25
P1433published inProceedings of the National Academy of Sciences of the United States of AmericaQ1146531
P1476titleMutational and transcriptional landscape of spontaneous gene duplications and deletions in Caenorhabditis elegans.
P478volume115

Reverse relations

cites work (P2860)
Q98773461A broad mutational target explains a fast rate of phenotypic evolution
Q92451746A major role for noncoding regulatory mutations in the evolution of enzyme activity
Q93379926Accelerated rates of large-scale mutations in the presence of copper and nickel
Q89857184A spontaneous complex structural variant in rcan-1 increases exploratory behavior and laboratory fitness of Caenorhabditis elegans
Q90389422Empirical measures of mutational effects define neutral models of regulatory evolution in Saccharomyces cerevisiae
Q99637281Epimutations driven by small RNAs arise frequently but most have limited duration in Caenorhabditis elegans
Q90407754Gene Balance Predicts Transcriptional Responses Immediately Following Ploidy Change in Arabidopsis thaliana
Q90717784Greater genetic and regulatory plasticity of retained duplicates in Epichloë endophytic fungi
Q60939386Old Trade, New Tricks: Insights into the Spontaneous Mutation Process from the Partnering of Classical Mutation Accumulation Experiments with High-Throughput Genomic Approaches
Q95309772The Importance of Genetic Redundancy in Evolution

Search more.