Novel tau fragments in cerebrospinal fluid: relation to tangle pathology and cognitive decline in Alzheimer's disease.

scientific article published on 13 December 2018

Novel tau fragments in cerebrospinal fluid: relation to tangle pathology and cognitive decline in Alzheimer's disease. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1007/S00401-018-1948-2
P932PMC publication ID6514201
P698PubMed publication ID30547227

P50authorHenrik ZetterbergQ6252048
Kaj BlennowQ28321550
Oskar HanssonQ30533735
Gunnar BrinkmalmQ42722971
Kina HöglundQ60977112
Thomas G BeachQ67218653
Lucilla ParnettiQ67469807
Erik PorteliusQ76736817
Tammaryn LashleyQ85290690
P2093author name stringHsu-Hsin Chen
Johan Gobom
Radu Constantinescu
Jessica Wahlgren
Claudia Cicognola
Nicholas C Cullen
Kristin Wildsmith
P2860cites workClinical diagnosis of Alzheimer's disease: report of the NINCDS-ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer's DiseaseQ27860795
Neuropathological stageing of Alzheimer-related changesQ27860862
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Mild cognitive impairment as a diagnostic entityQ29619568
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Characterization of novel CSF Tau and ptau biomarkers for Alzheimer's diseaseQ35014708
A comparative clinical, pathological, biochemical and genetic study of fused in sarcoma proteinopathiesQ35206942
Differential Mass Spectrometry Profiles of Tau Protein in the Cerebrospinal Fluid of Patients with Alzheimer's Disease, Progressive Supranuclear Palsy, and Dementia with Lewy Bodies.Q35938561
Arizona Study of Aging and Neurodegenerative Disorders and Brain and Body Donation ProgramQ36121377
Criteria for the diagnosis of corticobasal degenerationQ36661843
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CSF and blood biomarkers for the diagnosis of Alzheimer's disease: a systematic review and meta-analysisQ38805517
Role of the Tau N-terminal region in microtubule stabilization revealed by new endogenous truncated formsQ38874926
Cerebrospinal fluid levels of a 20-22 kDa NH2 fragment of human tau provide a novel neuronal injury biomarker in Alzheimer's disease and other dementias.Q38992796
AD-linked, toxic NH2 human tau affects the quality control of mitochondria in neuronsQ39035671
A NH2 tau fragment targets neuronal mitochondria at AD synapses: possible implications for neurodegeneration.Q39689304
Tau Protein Quantification in Human Cerebrospinal Fluid by Targeted Mass Spectrometry at High Sequence Coverage Provides Insights into Its Primary Structure Heterogeneity.Q40131661
Both total and phosphorylated tau are increased in Alzheimer's diseaseQ41765446
Interaction between NH(2)-tau fragment and Aβ in Alzheimer's disease mitochondria contributes to the synaptic deteriorationQ43509894
CSF Alzheimer's disease-like pattern in corticobasal syndrome: evidence for a distinct disorderQ44338777
Role of N-terminal tau domain integrity on the survival of cerebellar granule neurons.Q44654504
Early N-terminal changes and caspase-6 cleavage of tau in Alzheimer's disease.Q45050796
A peptide containing residues 26-44 of tau protein impairs mitochondrial oxidative phosphorylation acting at the level of the adenine nucleotide translocator.Q46412685
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Quantification of tau phosphorylated at threonine 181 in human cerebrospinal fluid: a sandwich ELISA with a synthetic phosphopeptide for standardizationQ49169032
Cleavage of Tau by calpain in Alzheimer's disease: the quest for the toxic 17 kD fragmentQ50537906
Accuracy of a panel of 5 cerebrospinal fluid biomarkers in the differential diagnosis of patients with dementia and/or parkinsonian disorders.Q50940972
Correlation of longitudinal cerebrospinal fluid biomarkers with cognitive decline in healthy older adults.Q51723038
Test-retest reliable coefficients and 5-year change scores for the MMSE and 3MS.Q51930054
Cerebrospinal fluid beta-amyloid(1-42) in Alzheimer disease: differences between early- and late-onset Alzheimer disease and stability during the course of disease.Q51983988
A new rating scale for Alzheimer's disease.Q53197509
Tau protein in cerebrospinal fluid: a biochemical marker for axonal degeneration in Alzheimer disease?Q53212854
Longitudinal stability of CSF biomarkers in Alzheimer's disease.Q53286684
Longitudinal stability evaluation of biomarkers and their correlation in cerebrospinal fluid and plasma from patients with Alzheimer's disease.Q53332329
Tau Kinetics in Neurons and the Human Central Nervous SystemQ57215461
SIC Task Force appraisal of clinical diagnostic criteria for parkinsonian disordersQ60932476
An online nano-LC-ESI-FTICR-MS method for comprehensive characterization of endogenous fragments from amyloid β and amyloid precursor protein in human and cat cerebrospinal fluidQ62128966
Diagnostic significance of tau protein in cerebrospinal fluid from patients with corticobasal degeneration or progressive supranuclear palsyQ73414107
N-terminal fragments of tau inhibit full-length tau polymerization in vitroQ79247556
P433issue2
P304page(s)279-296
P577publication date2018-12-13
P1433published inActa NeuropathologicaQ343168
P1476titleNovel tau fragments in cerebrospinal fluid: relation to tangle pathology and cognitive decline in Alzheimer's disease.
P478volume137

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