Interactive Repression of MYRF Self-Cleavage and Activity in Oligodendrocyte Differentiation by TMEM98 Protein.

scientific article published on 24 September 2018

Interactive Repression of MYRF Self-Cleavage and Activity in Oligodendrocyte Differentiation by TMEM98 Protein. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1523/JNEUROSCI.0154-18.2018
P932PMC publication ID6596239
P698PubMed publication ID30249802

P50authorHao HuangQ91634400
P2093author name stringJun Meng
Tao Tang
Zunyi Zhang
Yingchuan B Qi
Xuemei Hu
Mengsheng Qiu
Peng Teng
Junqing Du
P2860cites workMYRF is a membrane-associated transcription factor that autoproteolytically cleaves to directly activate myelin genesQ21090170
Mammalian transcription factor ATF6 is synthesized as a transmembrane protein and activated by proteolysis in response to endoplasmic reticulum stressQ22010800
An orthologue of the Myelin-gene Regulatory Transcription Factor regulates Dictyostelium prestalk differentiationQ24612888
A novel biochemical method to identify target genes of individual microRNAs: identification of a new Caenorhabditis elegans let-7 targetQ24644508
Myelin gene regulatory factor is a critical transcriptional regulator required for CNS myelinationQ24657511
Glial development: the crossroads of regeneration and repair in the CNSQ26823697
A presenilin-1-dependent gamma-secretase-like protease mediates release of Notch intracellular domainQ28141707
The SREBP pathway: regulation of cholesterol metabolism by proteolysis of a membrane-bound transcription factorQ28238069
Chronic stage multiple sclerosis lesions contain a relatively quiescent population of oligodendrocyte precursor cellsQ28258492
Myelin gene regulatory factor is required for maintenance of myelin and mature oligodendrocyte identity in the adult CNSQ28274507
Terminal differentiation of myelin-forming oligodendrocytes depends on the transcription factor Sox10Q28511593
A Bacteriophage tailspike domain promotes self-cleavage of a human membrane-bound transcription factor, the myelin regulatory factor MYRFQ28535280
Control of oligodendrocyte differentiation by the Nkx2.2 homeodomain transcription factorQ28591915
Common developmental requirement for Olig function indicates a motor neuron/oligodendrocyte connectionQ28594759
Myrf ER-Bound Transcription Factors Drive C. elegans Synaptic Plasticity via Cleavage-Dependent Nuclear TranslocationQ32874792
The Dual-specificity phosphatase Dusp15 is regulated by Sox10 and Myrf in Myelinating Oligodendrocytes.Q32874884
Tmeff2 is expressed in differentiating oligodendrocytes but dispensable for their differentiation in vivoQ33671731
Homo-trimerization is essential for the transcription factor function of Myrf for oligodendrocyte differentiationQ33701686
Biology of oligodendrocyte and myelin in the mammalian central nervous systemQ33939997
Premyelinating oligodendrocytes in chronic lesions of multiple sclerosisQ34109903
Why does remyelination fail in multiple sclerosis?Q34147437
Mutation in TMEM98 in a large white kindred with autosomal dominant nanophthalmos linked to 17p12-q12.Q34421044
Oligodendrocyte warsQ34478825
Markers of central nervous system glia and neurons in vivo during normal and pathological conditionsQ34640261
The Secreted Form of Transmembrane Protein 98 Promotes the Differentiation of T Helper 1 CellsQ36030309
Generation of mice encoding a conditional allele of Nkx2.2.Q37018093
Regulation of the timing of oligodendrocyte differentiation: mechanisms and perspectivesQ37144056
Genetic evidence that Nkx2.2 and Pdgfra are major determinants of the timing of oligodendrocyte differentiation in the developing CNS.Q37507612
New Olig1 null mice confirm a non-essential role for Olig1 in oligodendrocyte developmentQ37525408
Oligodendrocytes: Myelination and Axonal SupportQ38534982
Evolution of the CNS myelin gene regulatory programQ38609379
Identification of transmembrane protein 98 as a novel chemoresistance-conferring gene in hepatocellular carcinoma.Q39017316
Role of Oligodendrocyte Dysfunction in Demyelination, Remyelination and Neurodegeneration in Multiple SclerosisQ39091396
Manipulating gene expression with replication-competent retrovirusesQ41044615
CG-4, a new bipotential glial cell line from rat brain, is capable of differentiating in vitro into either mature oligodendrocytes or type-2 astrocytesQ41645595
Oligodendrocyte progenitor cell susceptibility to injury in multiple sclerosis.Q50927305
Isolation and culture of rat and mouse oligodendrocyte precursor cells.Q51984231
Induction of oligodendrocyte differentiation by Olig2 and Sox10: evidence for reciprocal interactions and dosage-dependent mechanisms.Q52002151
Efficient targeting of gene expression in chick embryos by microelectroporation.Q52175897
Multiple sclerosis: remyelination in acute lesionsQ72080198
The leukodystrophies: a window to myelinQ72659548
Quantification of oligodendrocyte progenitor cells in human and cat optic nerve: implications for endogenous repair in multiple sclerosisQ84409628
LeukodystrophiesQ88360528
P433issue46
P921main subjectMyelin regulatory factorQ21987710
Transmembrane protein 98Q21990737
P304page(s)9829-9839
P577publication date2018-09-24
P1433published inJournal of NeuroscienceQ1709864
P1476titleInteractive Repression of MYRF Self-Cleavage and Activity in Oligodendrocyte Differentiation by TMEM98 Protein
P478volume38

Reverse relations

cites work (P2860)
Q102141661Novel TMEM98, MFRP, PRSS56 variants in a large United States high hyperopia and nanophthalmos cohort
Q91634404Stage-dependent regulation of oligodendrocyte development and enhancement of myelin repair by dominant negative Master-mind 1 protein
Q90666595Stage-specific regulation of oligodendrocyte development by Hedgehog signaling in the spinal cord
Q92802239TMEM98 is a negative regulator of FRAT mediated Wnt/ß-catenin signalling
Q91640320Transcriptional control of myelination and remyelination
Q64885738Variants in myelin regulatory factor (MYRF) cause autosomal dominant and syndromic nanophthalmos in humans and retinal degeneration in mice.

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