Resveratrol protects against asthma-induced airway inflammation and remodeling by inhibiting the HMGB1/TLR4/NF-κB pathway.

scientific article published on 20 May 2019

Resveratrol protects against asthma-induced airway inflammation and remodeling by inhibiting the HMGB1/TLR4/NF-κB pathway. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.3892/ETM.2019.7594
P932PMC publication ID6566090
P698PubMed publication ID31258683

P2093author name stringWenbo Zhang
Kaihong Xu
Huanhuan Jiang
Junyan Duan
P2860cites workA critical cysteine is required for HMGB1 binding to Toll-like receptor 4 and activation of macrophage cytokine releaseQ24321082
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Release of high mobility group box 1 by dendritic cells controls T cell activation via the receptor for advanced glycation end productsQ28116270
Neutrophil-derived elastase induces TGF-beta1 secretion in human airway smooth muscle via NF-kappaB pathwayQ28217923
The secretion of HMGB1 is required for the migration of maturing dendritic cellsQ28268065
High mobility group 1 protein (HMG-1) stimulates proinflammatory cytokine synthesis in human monocytesQ28574795
Resveratrol suppresses TNF-induced activation of nuclear transcription factors NF-kappa B, activator protein-1, and apoptosis: potential role of reactive oxygen intermediates and lipid peroxidationQ31393490
Stress and asthma: novel insights on genetic, epigenetic, and immunologic mechanismsQ34613768
Resveratrol Inhibits Nitric Oxide-Induced Apoptosis via the NF-Kappa B Pathway in Rabbit Articular ChondrocytesQ34657550
Dendritic cell regulation of immune responses: a new role for interleukin 2 at the intersection of innate and adaptive immunityQ35139530
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High-mobility group box-1 impairs memory in mice through both toll-like receptor 4 and Receptor for Advanced Glycation End ProductsQ35448830
Biological effects of the plant-derived polyphenol resveratrol in human articular cartilage and chondrosarcoma cellsQ35899103
Resveratrol, a polyphenol phytoalexin, protects cardiomyocytes against anoxia/reoxygenation injury via the TLR4/NF-κB signaling pathwayQ36613722
High mobility group box 1 contributes to the pathogenesis of experimental pulmonary hypertension via activation of Toll-like receptor 4Q36621780
trans-Resveratrol, an extract of red wine, inhibits human eosinophil activation and degranulationQ37002367
Biological and medicinal properties of grapes and their bioactive constituents: an update.Q37559658
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Anti-inflammatory effect of resveratrol by inhibition of IL-8 production in LPS-induced THP-1 cellsQ39770687
Eosinophils oxidize damage-associated molecular pattern molecules derived from stressed cellsQ39793141
Resveratrol inhibits IL-1 beta-induced stimulation of caspase-3 and cleavage of PARP in human articular chondrocytes in vitroQ40227620
HMGB1 signals through toll-like receptor (TLR) 4 and TLR2.Q40249835
Resveratrol blocks interleukin-1beta-induced activation of the nuclear transcription factor NF-kappaB, inhibits proliferation, causes S-phase arrest, and induces apoptosis of acute myeloid leukemia cellsQ40594673
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Recognition and management of asthma in children and young peopleQ41355975
Different anti-adipogenic effects of bio-compounds on primary visceral pre-adipocytes and adipocytesQ41833670
Penehyclidine hydrochloride inhibits the release of high-mobility group box 1 in lipopolysaccharide-activated RAW264.7 cells and cecal ligation and puncture-induced septic miceQ44788162
Resveratrol inhibits right ventricular hypertrophy induced by monocrotaline in rats.Q45946127
Effect of resveratrol in experimental osteoarthritis in rabbitsQ46481820
Regulation of inflammation signalling by resveratrol in human chondrocytes in vitroQ46933367
Immunization with an adenovirus-vectored TB vaccine containing Ag85A-Mtb32 effectively alleviates allergic asthmaQ47665045
HMGB1 contributes to the development of acute lung injury after hemorrhageQ47868867
The Effects of Resveratrol on Inflammation and Oxidative Stress in a Rat Model of Chronic Obstructive Pulmonary Disease.Q48362779
Imperatorin exerts antiallergic effects in Th2-mediated allergic asthma via induction of IL-10-producing regulatory T cells by modulating the function of dendritic cells.Q51523792
HMGB1 binding to receptor for advanced glycation end products enhances inflammatory responses of human bronchial epithelial cells by activating p38 MAPK and ERK1/2.Q51641769
Activation of gene expression in human neutrophils by high mobility group box 1 proteinQ73087842
HMG-1 as a mediator of acute lung inflammationQ74279708
T cell activation by TLRs: a role for TLRs in the adaptive immune responseQ81039397
[ROLE OF PSYCHOLOGICAL FACTORS IN THE ETIOLOGY OF ASTHMA IN CHILDREN]Q85482643
Resveratrol inhibits pulmonary fibrosis by regulating miR-21 through MAPK/AP-1 pathwaysQ88906462
Silencing of H4R inhibits the production of IL-1β through SAPK/JNK signaling in human mast cellsQ88971805
P433issue1
P921main subjectasthmaQ35869
NF-κBQ411114
P304page(s)459-466
P577publication date2019-05-20
P1433published inExperimental and Therapeutic MedicineQ23979083
P1476titleResveratrol protects against asthma-induced airway inflammation and remodeling by inhibiting the HMGB1/TLR4/NF-κB pathway
P478volume18

Reverse relations

cites work (P2860)
Q99608766Resveratrol extracted from Chinese herbal medicines: A novel therapeutic strategy for lung diseases
Q91711982Targeting Inflammation Driven by HMGB1

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