Mitochondrial Respiratory Function in Peripheral Blood Cells from Huntington's Disease Patients.

scientific article published on 11 February 2016

Mitochondrial Respiratory Function in Peripheral Blood Cells from Huntington's Disease Patients. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1002/MDC3.12308
P932PMC publication ID6178737
P698PubMed publication ID30363579

P50authorMagnus J HanssonQ43208349
Johannes K H EhingerQ85484752
P2093author name stringEskil Elmér
Saori Morota
Gesine Paul
P2860cites workCytochrome c oxidase and mitochondrial F1F0-ATPase (ATP synthase) activities in platelets and brain from patients with Alzheimer's diseaseQ24294639
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Characterization of cybrid cell lines containing mtDNA from Huntington's disease patients.Q30304195
N-terminal mutant huntingtin associates with mitochondria and impairs mitochondrial traffickingQ30486372
Beyond the brain: widespread pathology in Huntington's diseaseQ33483188
Patients with sepsis exhibit increased mitochondrial respiratory capacity in peripheral blood immune cellsQ33752546
Genome-wide expression profiling of human blood reveals biomarkers for Huntington's disease.Q33911613
Involvement of mitochondrial complex II defects in neuronal death produced by N-terminus fragment of mutated huntingtinQ34483577
Mutant huntingtin binds the mitochondrial fission GTPase dynamin-related protein-1 and increases its enzymatic activityQ34634421
Low anaerobic threshold and increased skeletal muscle lactate production in subjects with Huntington's diseaseQ34838143
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An insight into ultrastructural and morphological alterations of platelets in neurodegenerative diseasesQ37853182
Peripheral mitochondrial dysfunction in Alzheimer's disease: focus on lymphocytesQ38028375
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Mutant huntingtin expression induces mitochondrial calcium handling defects in clonal striatal cells: functional consequencesQ40231756
Severe ultrastructural mitochondrial changes in lymphoblasts homozygous for Huntington disease mutationQ40351019
Mutant huntingtin directly increases susceptibility of mitochondria to the calcium-induced permeability transition and cytochrome c releaseQ40551652
Aberrant A2A receptor function in peripheral blood cells in Huntington's diseaseQ40564008
Early mitochondrial calcium defects in Huntington's disease are a direct effect of polyglutamines.Q40721588
Huntingtin is required for normal hematopoiesisQ40902755
Regional mitochondrial respiratory activity in Huntington's disease brainQ41360902
Oxidative damage and metabolic dysfunction in Huntington's disease: selective vulnerability of the basal ganglia.Q42438521
Mitochondrial impairment in patients and asymptomatic mutation carriers of Huntington's diseaseQ45259959
Evidence of apoptosis and mitochondrial abnormalities in peripheral blood cells of Huntington's disease patients.Q45290069
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Mitochondrial defect in Huntington's disease caudate nucleusQ45291734
Analysis of the repressor element-1 silencing transcription factor/neuron-restrictive silencer factor occupancy of non-neuronal genes in peripheral lymphocytes from patients with Huntington's diseaseQ45292252
Evidence for a defect in NADH: ubiquinone oxidoreductase (complex I) in Huntington's diseaseQ45294442
Distribution of phosphate-activated glutaminase, succinic dehydrogenase, pyruvate dehydrogenase and gamma-glutamyl transpeptidase in post-mortem brain from Huntington's disease and agonal casesQ45296514
Huntingtin is cleaved by caspases in the cytoplasm and translocated to the nucleus via perinuclear sites in Huntington's disease patient lymphoblastsQ45296864
Biochemical abnormalities and excitotoxicity in Huntington's disease brain.Q45297145
Genotype-, aging-dependent abnormal caspase activity in Huntington disease blood cells.Q45302615
Amyotrophic lateral sclerosis: oxidative energy metabolism and calcium homeostasis in peripheral blood lymphocytesQ48910244
Mitochondrial respiration in human viable platelets--methodology and influence of gender, age and storage.Q52631832
Unified Huntington's disease rating scale: Reliability and consistencyQ57422462
Platelet mitochondrial function in Parkinson's disease. The Royal Kings and Queens Parkinson Disease Research GroupQ67973678
Abnormalities of the electron transport chain in idiopathic Parkinson's diseaseQ69361952
Mitochondrial complex I deficiency and ATP/ADP ratio in lymphocytes of amyotrophic lateral sclerosis patientsQ83748135
Mitochondrial diseasesQ83827338
Increased apoptosis of Huntington disease lymphoblasts associated with repeat length-dependent mitochondrial depolarizationQ95810356
P433issue5
P921main subjectHuntington's diseaseQ190564
P304page(s)472-482
P577publication date2016-02-11
P1433published inMovement disorders clinical practiceQ27725493
P1476titleMitochondrial Respiratory Function in Peripheral Blood Cells from Huntington's Disease Patients
P478volume3