[35S]t-butylbicyclophosphorothionate binds with high affinity to brain-specific sites coupled to gamma-aminobutyric acid-A and ion recognition sites

scientific article published on 01 March 1983

[35S]t-butylbicyclophosphorothionate binds with high affinity to brain-specific sites coupled to gamma-aminobutyric acid-A and ion recognition sites is …
instance of (P31):
scholarly articleQ13442814

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P698PubMed publication ID6300642

P2093author name stringM Richardson
J E Casida
E Saederup
R F Squires
P433issue2
P304page(s)326-336
P577publication date1983-03-01
P1433published inMolecular PharmacologyQ1943386
P1476title[35S]t-butylbicyclophosphorothionate binds with high affinity to brain-specific sites coupled to gamma-aminobutyric acid-A and ion recognition sites
P478volume23

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cites work (P2860)
Q41130141?In vivo? administration of valproate decreases t-[35S]butylbicyclophosphorothionate binding in the rat brain
Q36546223A review of evidence for GABergic predominance/glutamatergic deficit as a common etiological factor in both schizophrenia and affective psychoses: More support for a continuum hypothesis of ?functional? psychosis
Q24609507Absinthe and gamma-aminobutyric acid receptors
Q33805864Abuse Potential of Soma: the GABA(A) Receptor as a Target
Q49093413Additivities of compounds that increase the numbers of high affinity [3H]muscimol binding sites by different amounts define more than 9 GABA(A) receptor complexes in rat forebrain: implications for schizophrenia and clozapine research
Q48228313Affinities of barbiturates for the GABA-receptor complex and A1 adenosine receptors: a possible explanation of their excitatory effects
Q51649230Alterations in t-butylbicyclophosphorothionate binding in the brains of lidocaine-kindled rats.
Q51607669An autoradiographic study comparing the interactions of 3 alpha-OH-5 alpha-pregnan-20-one, pregnenolone sulfate and pentobarbital with [3S]-TBPS binding sites and their modulation by GABA in different structures of the rat brain.
Q91905899An update on the anxiolytic and neuroprotective properties of etifoxine: from brain GABA modulation to a whole-body mode of action
Q48663996Analysis of γ-aminobutyric acid (GABA) type A receptor subtypes using isosteric and allosteric ligands
Q42549228Antagonism of convulsions but failure to enhance GABA(A) receptor function by felbamate in mice tolerant to diazepam.
Q70211519Anticonvulsant drug actions on neurons in cell culture
Q71656448Anticonvulsant effect of felbamate in the pentylenetetrazole kindling model of epilepsy in the rat
Q48547249Autoradiographic analysis of [35S]TBPS binding in entorhinal cortex-kindled rat brains
Q39499651Benzodiazepine receptors resolved
Q51228073Beta-carbolines can enhance or antagonize the effects of punishment in mice.
Q41932163Bicuculline blocks nicotinic acetylcholine response in isolated intermediate lobe cells of the pig
Q70185999Bidirectional effects of benzodiazepine receptor ligands against picrotoxin- and pentylenetetrazol-induced seizures
Q40919077Biphasic modulation of GABA(A) receptor binding by steroids suggests functional correlates
Q37382995Brain regional distribution of GABA(A) receptors exhibiting atypical GABA agonism: roles of receptor subunits
Q47730991Brain regional heterogeneity of pH effects on GABA(A) receptor-associated [35s]TBPS binding
Q44490771Caffeine analogs: effects on ryanodine-sensitive calcium-release channels and GABAA receptors
Q42178211Characterization of U‐97775 as a GABAA receptor ligand of dual functionality in cloned rat GABAA receptor subtypes
Q36052617Characterization of [35S]t-butylbicyclophosphorothionate ([35S]TBPS) binding to GABAA receptors in postmortem human brain
Q28259562Characterization of seizures induced by acute and repeated exposure to tetramethylenedisulfotetramine
Q48357979Clozapine and several other antipsychotic/antidepressant drugs preferentially block the same 'core' fraction of GABA(A) receptors
Q73031455Clozapine and some other antipsychotic drugs may preferentially block the same subset of GABA(A) receptors
Q77799992Clozapine's antipsychotic effects do not depend on blockade of 5-HT3 receptors
Q50663402Differential effects of etifoxine on anxiety-like behaviour and convulsions in BALB/cByJ and C57BL/6J mice: Any relation to overexpression of central GABAA receptor beta2 subunits?
Q42563409Differential effects of petit mal anticonvulsants and convulsants on thalamic neurones: GABA current blockade
Q43611885Do antiepileptics phenytoin, carbamazepine, and loreclezole show GABA(A) receptor subtype selectivity in rat brain sections?
Q70162067Dose pipecolic acid interact with the central GABA-ergic system?
Q41452019Effects of GABA and various allosteric ligands on TBPS binding to cloned rat GABA(A) receptor subtypes
Q67676405Effects of GABAA receptor ligands on noradrenaline concentration and beta-adrenoceptor binding in mouse cerebral cortex
Q48350528Effects of pentylenetetrazol on GABA-A/benzodiazepine/picrotoxinin receptor complexes in rat brain regions
Q48853069Effects of the antidepressant pirlindole and its dehydro-derivative on the activity of monoamine oxidase-A and on GABAA receptors
Q40709452Effects of the antiepileptic drug valproate on metabolism and function of inhibitory and excitatory amino acids in the brain
Q41812805Electrophysiological study of SR 42641, a novel aminopyridazine derivative of GABA: antagonist properties and receptor selectivity of GABAA versus GABAB responses
Q41341443Enhancement by GABA of the association rate of picrotoxin and tert‐butylbicyclophosphorothionate to the rat cloned α1β2γ2 GABAA receptor subtype
Q38270955Ethanol and the benzodiazepine-GABA receptor-ionophore complex
Q35609817Ethanol stimulates gamma-aminobutyric acid receptor-mediated chloride transport in rat brain synaptoneurosomes
Q40338809Evidence for a reduction of coupling between GABAA receptor agonist and ionophore binding sites by inorganic phosphate
Q44732947Evidence that clomethiazole interacts with the macromolecular GABA A-receptor complex in the central nervous system and in the anterior pituitary gland
Q48812960Evidence that genetic differences in habituation and GABAergic mechanisms may be related to sensitivity to ethanol and development of ethanol tolerance in mice
Q28328247Foot-shock stress enhances the increase of [35S]TBPS binding in the rat cerebral cortex and the convulsions induced by isoniazid
Q37876836From binding studies to the molecular biology of GABA receptors
Q42847416GABA receptors on the somatic muscle cells of the parasitic nematode, Ascaris suum: stereoselectivity indicates similarity to a GABAA-type agonist recognition site
Q46217028GABAA receptor subtype selectivity of the proconvulsant rodenticide TETS.
Q33767488GABAA receptor target of tetramethylenedisulfotetramine
Q50178492GABAA receptor: Positive and negative allosteric modulators
Q28139887Honokiol and magnolol increase the number of [3H] muscimol binding sites three-fold in rat forebrain membranes in vitro using a filtration assay, by allosterically increasing the affinities of low-affinity sites
Q39094698Influence of tetramethylenedisulfotetramine on synchronous calcium oscillations at distinct developmental stages of hippocampal neuronal cultures
Q39443162Influences on blockade by t-butylbicyclo-phosphoro-thionate of GABA(A) receptor spontaneous gating, agonist activation and desensitization.
Q34047528Interaction of picrotoxin with GABAA receptor channel-lining residues probed in cysteine mutants.
Q34560840Interactions of isamoltane (CGP 361A), an anxiolytic phenoxypropanolamine derivative, with 5-HT1 receptor subtypes in the rat brain
Q46781594Investigation of the anticonvulsive effect of acute immobilization stress in anxious Balb/cByJ mice using GABA A-related mechanistic probes
Q64241687Mechanisms Underlying Neuroprotection by the NSAID Mefenamic Acid in an Experimental Model of Stroke
Q35041852Modulation by bicuculline and penicillin of the block by t-butyl-bicyclo-phosphorothionate (TBPS) of GABA(A)-receptor mediated Cl(-)-current responses in rat striatal neurones
Q41865800Modulation of the GABAA receptor by depressant barbiturates and pregnane steroids
Q39338540Molecular biology of inhibitory amino acid receptors
Q48262606Mono N-aryl ethylenediamine and piperazine derivatives are GABAA receptor blockers: implications for psychiatry
Q48297581Multiple mechanisms of picrotoxin block of GABA-induced currents in rat hippocampal neurons
Q55036933On the mechanism of action of picrotoxin on GABA receptor channels in dissociated sympathetic neurones of the rat.
Q41986434PET analysis of alcohol interaction with the brain disposition of [11C]flumazenil
Q37054777Picrotoxin dramatically speeds the mammalian circadian clock independent of Cys-loop receptors
Q34597191Picrotoxin-like channel blockers of GABAA receptors
Q34559437Protection against the lethal effects of pentobarbital in mice by a benzodiazepine receptor inverse agonist, 6,7-dimethoxy-4-ethyl-3-carbomethoxy-beta-carboline
Q90319435Rational approaches for the design of various GABA modulators and their clinical progression
Q35781917Role of GABAergic antagonism in the neuroprotective effects of bilobalide.
Q46056664Sensitive Immunoassay for Detection and Quantification of the Neurotoxin, Tetramethylenedisulfotetramine
Q38327413Steroid and barbiturate modulation of the GABAa receptor. Possible mechanisms
Q39339271Steroid modulation of the GABA/benzodiazepine receptor-linked chloride ionophore
Q34597062Structural model for gamma-aminobutyric acid receptor noncompetitive antagonist binding: widely diverse structures fit the same site
Q35035938Structure-activity correlations for interactions of bicyclophosphorus esters and some polychlorocycloalkane and pyrethroid insecticides with the brain-specific t-butylbicyclophosphorothionate receptor
Q70812723Subtype specificity of gamma-aminobutyric acid type A receptor antagonism by clozapine
Q36486976Tetramethylenedisulfotetramine alters Ca²⁺ dynamics in cultured hippocampal neurons: mitigation by NMDA receptor blockade and GABA(A) receptor-positive modulation
Q43868220The GABAA receptor family in the mammalian brain
Q34481002The diversity of GABAA receptors. Pharmacological and electrophysiological properties of GABAA channel subtypes
Q42847623The modulation by chlormethiazole of the GABAA-receptor complex in rat brain
Q34378869The neurobiology of alcohol consumption and alcoholism: an integrative history
Q37410386The permeability of gamma-aminobutyric acid-gated chloride channels is described by the binding of a "cage" convulsant, t-butylbicyclophosphoro[35S]thionate
Q35044308The sleep hormone oleamide modulates inhibitory ionotropic receptors in mammalian CNS in vitro
Q49142685Thermodynamics and kinetics of t-butylbicyclophosphorothionate binding differentiate convulsant and depressant barbiturate stereoisomers acting via GABAA ionophores
Q51227812Tolerance to the benzodiazepine diazepam in an animal model of anxiolytic activity.
Q52463386Toxicity of chlorinated bornane (toxaphene) residues isolated from Great Lakes lake trout (Salvelinus namaycush).
Q54009247Use of 82Br- radiotracer to study transmembrane halide flux: the effect of a tranquilizing drug, chlordiazepoxide on channel opening of a GABAA receptor.

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