Cytotoxic and antitumor antibiotics produced by microorganisms

scientific article published on 01 January 1976

Cytotoxic and antitumor antibiotics produced by microorganisms is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/S0065-2164(08)70114-X
P698PubMed publication ID998366

P2093author name stringJ. Fuska
B. Proksa
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Carcinogenic activity of a series of reactive lactones and related substancesQ36126663
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Kundrymycin, a new tumor-inhibitory antibiotic. II. Isolation, chemical characterization and biological activityQ71775462
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Antiviral activity of N,N′-dimethyl-epidithiapiperazinedione, a synthetic compound related to the gliotoxins, LL-S88α and β, chetomin and the sporidesminsQ72220494
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Inhibition of dopamine beta-hydroxylase by aquayamycinQ72230414
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The interaction of mitomycin C with deoxyribonucleic acid in vitroQ72287991
Structure of sangivamycinQ72294255
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Structure of streptozotocinQ72353904
Permeability changes caused by desertomycin in fungal, animal and plant cellsQ72400043
Pleomycin-induced mitotic inhibition and chromosomal abnormalities in cultured human leucocytesQ72416256
Actinomycin and Antitumor AntibioticsQ72420881
Destructive processing of the 45-S ribosomal precursor in the presence of 5-azacytidineQ93737138
Complex formation of daunomycin with double-stranded RNAQ93749456
Differential inhibitory effects of antibiotics on the biosynthesis of envelope proteins of Escherichia coliQ93751556
L-asparaginase production during static incubation of aerobically grown Escherichia coli BQ93752621
On the inhibition of ribonucleic synthesis in Bacillus subtilis cells by steffimycinQ93776145
Interaction of kanchanomycin with nucleic acids. I. Physical properties of the complexQ93790217
Denamycin, a new antibioticQ93792328
The Degradation of Ribosomal RNA in E. coli by Mitomycin C and AF-5, Preferential Inhibitors of DNA SynthesisQ93800808
Nucleoside antibiotics. Asymmetric incorporation of glutamic acid and acetate into the maleimide ring of showdomycin by Streptomyces showdoensisQ93833673
In vivo effect of aflatoxin B(1), on protein synthesis in rat liverQ94046875
Effects of cordycepin on RNA sythesis in Physarum polycephalumQ44915567
The interference of the macrolide antibiotics with mitochondrial protein synthesis.Q44928319
The reaction of anthramycin with DNA. 3. Properties of the complexQ44938483
In vivo and enzymatic conversion of toyocamycin to sangivamycin by Streptomyces rimosusQ44947090
Effect of actinomycin and puromycin on the deoxyribonuclease activity in P. lividus embryos at various stages of developmentQ44950432
Inhibition of guanine nucleotide biosynthesis by mycophenolic acid in Yoshida ascites cellsQ44967105
Zorbamycin and related antibiotics. I. Production, isolation and characterizationQ44997509
Verticillin A, a new antibiotic from Verticillium spQ45001067
Inhibition of alcohol and lactic dehydrogenases by patulin and penicillic acid in vitroQ45086687
Antibiotics produced by Streptomyces. VII. Cytotetrin, a new antitumor antibioticQ45126510
Geldanamycin, a new antibioticQ45194224
Mode of action of xanthocillin X monomethylether on multiplication of Newcastle disease virus in cultured cells. (studies on antiviral and antitumor antibiotics. XV).Q45809811
Antiviral Activity of 9- -D-Arabinofuranosyladenine (ara-A) Against Gross Murine Leukemia Virus in VitroQ45814731
Effects of Actinomycin D on Early Steps of Replication in vitro of Murine Sarcoma Virus (Moloney)Q45814958
Analysis of the early and late products of the DNA polymerase of friend murine leukemia virus with actinomycin D.Q45815320
Inhibitory effect of streptonigrin on a murine sarcoma virus-induced tumor cell line (MSC) and selection of drug-resistant clonesQ45819228
Rifampicin and distamycin A as inhibitors of Rous sarcoma virus reverse transcriptase.Q45821217
Bleomycin, an inhibitor of vaccinia virus replicationQ45826487
Interaction between murine type-C virus RNA-directed DNA polymerases and rifamycin derivatives.Q45826564
Persistence of Rous sarcoma virus genome in AKR mouse sarcoma cells resistant to chromomycin A 3 and actinomycin D.Q45827193
Funiculosin, a new antibiotic. I. Isolation, biological and chemical properties (studies on antiviral and antitumor antibiotics. 8).Q46391329
Effects of Actinomycin D, Toyocamycin and Cycloheximide on the Synthesis of Low-Molecular-Weight Nuclear RNAs in HeLa CellsQ47366960
Mode of Action of Enomycin, an Antitumor Antibiotic of High Molecular Weight I. Inhibition of Protein SynthesisQ47408121
The binding of RNA polymerase to DNAQ47659735
Effects of cycloheximide, D-threo-chloramphenicol, erythromycin and actinomycin D on De-novo synthesis of cytoplasmic and mitochondrial proteins in the cotyledons of germinating pea seedsQ47695125
Pactamycin, an antibiotic that inhibits protein synthesisQ47707143
Inhibition of Protein Synthesis by Amicetin, a Nucleoside Antibiotic*Q47709715
The Effect of Chromomycin A3 upon Nucleic Acid Metabolism of Bacillus subtilisSB-15Q47714537
Antineoplastic activity of highly purified bacterial glutaminasesQ47770343
Isolation and properties of L-asparaginases from Escherichia coli.Q47779610
Effect of steffimycin on cell-free polypeptide synthesisQ47798376
Mechanism of action of phenomycin, a tumor-inhibitory polypeptideQ47807951
Biochemical mechanism of action of substance B-44-PQ47808274
Cross resistance of Escherichia coli B ribosomes to inhibition of the puromycin reaction by erythromycin, spiramycin and chloramphenicolQ47813780
Replication of RNA bacteriophage R23. II. Inhibition of phage-specific RNA synthesis by phleomycinQ47814466
Structural basis for inhibition of protein synthesis by the aminoacyl-aminohexosyl-cytosine group of antibioticsQ47836836
Differential effects of cycloheximide and other inhibitors of protein synthesis on in vivo ribosomal RNA synthesis in Achlya bisexualisQ47853102
Cycloheximide: A specific inhibitor of protein synthesis and intercellular ion transport in plant rootsQ47863512
Effect of neocarzinostatin on V-79 Chinese hamster cells in vitroQ47900879
Actinomycin D and the regulation of enzyme biosynthesis during development of Dictyostelium discoideumQ47908455
Ultrastructural investigation of the effect of DNA, RNA, and protein synthesis inhibitors on ribosome crystallizationQ47911341
Biopolymers in drug technology: the use of DNA in purifying phleomycinQ47932212
Protein synthesis in rabbit reticulocytes: Evidence for the synthesis of initial dipeptides in the presence of pactamycinQ47945933
Reversible association of cytochalasin B with the human erythrocyte membrane. Inhibition of glucose transport and the stoichiometry of cytochalasin bindingQ47947482
Alteration of 23 S ribosomal RNA and erythromycin-induced resistance to lincomycin and spiramycin in Staphylococcus aureusQ47973078
Aflatoxin B1 and actinomycin D effects on histone acetylation and deacetylation in the liverQ47997138
Differential effects of cycloheximide on protein and RNA synthesis as a function of doseQ47998716
Microsome-dependent binding of aflatoxin B1 to DNA, RNA, polyribonucleotides and protein in vitroQ48003940
Inhibition of DNA synthesis in synchronized Chinese hamster cells treated in G1 or early S phase with cycloheximide or puromycinQ48024427
Time-lapse cinematographic studies on the inhibition of cell motility by puromycin in cultured nervous tissueQ48564194
Letter: New components of bleomycin.Q54494015
[Effect of rifamycin SV on the in vitro induced immune response]Q54509394
Interaction of ribonucleic acid polymerase from Escherichia coli with deoxyribonucleic acid. Inhibition of ribonucleic acid synthesis by interaction of luteoskyrin with the transcription complexQ54626088
Inhibition of muscle aldolase by penicillic acid and patulin In vitroQ54640575
Effect of cordycepin (3'-desoxyadenosine) on polytene chromosomes of Chironomus pallidivittatus salivary glands.Q54655270
Isolation, structural elucidation, biological properties, and biosynthesis of maleimycin, a new bicyclic maleimide antibiotic isolated from the culture filtrates of Streptomyces showdoensis.Q54703744
Studies on antitumor polysaccharides of Flammulina velutipes (Curt. ex Fr.) Sing. I.Q54753838
Specific inhibition of viral ribonucleic acid replication by Gliotoxin.Q54767129
Actinomycin D-induced breakage of human KB cell DNA.Q54793385
MITOMYCINS AND PORFIROMYCIN: CHEMICAL MECHANISM OF ACTIVATION AND CROSS-LINKING OF DNA.Q55037555
Effect of mitomycin C on protein synthesis in human neoplastic cell lines.Q55494464
Beef Liver Glucose Dehydrogenase. I. Purification and PropertiesQ56915944
Physiological and Genetic Effects of 8-Azaguanine on Aspergillus nidulansQ58957462
Mycophenolic Acid: an Anti-cancer Compound with Unusual PropertiesQ58979200
Selective Inhibition of Biosynthesis of Ribonucleic Acid in Mammalian Cells by Chromomycin A3Q59016716
Teratogenic Response by Hamsters, Rats and Mice to Aflatoxin B1Q59032046
Decumbin, a New Compound from a Species of PenicilliumQ59060268
AnnouncementsQ59068159
Azaserine, A New Tumour-Inhibitory Substance: Studies with Crocker Mouse Sarcoma 180Q59071479
Antineoplastic Activity of Aflatoxin B1Q59072857
Induction of Renal Tumour by Streptozotocin in RatsQ59086737
Trichothecin : an Antifungal Metabolic Product of Trichothecium roseum LinkQ59087396
Interaction of Actinomycin with Deoxyribonucleic AcidQ59098283
Biosynthesis of the Cytochalasans. Part III.13C-NMR. of cytochalasin B (phomin) and cytochalasin D. Incorporation of [1-13C]- and [2-13C]-sodium acetateQ60481240
Interactions of the antibiotic, distamycin A, with native DNA and with synthetic duplex polydeoxyribonucleotidesQ64356643
Mode of action of alanosineQ65002869
Simultaneous ribosomal resistance to trichodermin and anisomycin in Saccharomyces cerevisiae mutantsQ66894505
Identity of the antitumor antibiotic litmomycin with granaticin AQ66909726
Cytochalasin B inhibits stabilisation of adhesions in fast-aggregating cell systemsQ66910828
Antitumor Agents II: Nitrogen Analogs of Mycophenolic AcidQ66935678
Interaction of antibiotics with deoxyribonucleic acid. I. Sensitivity of the complexes to nucleolytic enzymesQ67235385
Combination chemotherapy with L-asparaginase (EC-2) using P1798 lymphosarcomaQ67238497
Antitumor activities of bacterial leucine dehydrogenase and glutaminase AQ67255433
Differences in eukaryotic ribosomes detected by the selective action of an antibioticQ67261746
Stimulation of actinomycin D-binding to eutherian sperm chromatin by reduction of disulphide bondsQ67271251
The action of daunomycin on Mycoplasma-infected HeLa cells in cultureQ67280267
Minimycin, a new antibioticQ67284179
Violamycin, a new red-pigment antibioticQ68368174
Filipin as a fluorescent probe for the location of cholesterol in the membranes of fragmented sarcoplasmic reticulumQ68503391
Mithramycin in the treatment of metastatic Ewing's sarcomaQ68508742
Immunosuppressive activity of some new cytostatic agentsQ68515547
Effects of daunomycin and anthramycin on electrocardiogram and mitochondrial metabolism of the rat heartQ68531200
On the mode of action of 7-deaza-adenosine (tubercidin)Q68569263
Polyribosome breakdown in rat liver following administration of 8-azaguanineQ68569349
An epidithiapiperazinedione antiviral agent from Aspergillus terreusQ68586044
Ascochlorin, a new antibiotic, found by the paper-disc agar-diffusion method. I. Isolation, biological and chemical properties of ascochlorin. (Studies on antiviral and antitumor antibiotics. I)Q68590741
Interaction of filipin 3 and amphotericin B with lecithin-sterol vesicles and cellular membranes. Spectral and electron microscope studiesQ36504377
The induction of an ATP-energized mitochondrial volume change by the combination of the -S-S- compound gliotoxin with either a respiratory inhibitor or an uncoupling agentQ36529439
Cycloheximide induction of xenotropic type C virus from synchronized mouse cells: metabolic requirements for virus activationQ36529722
Supplementary data on crotocin--an antifungal antibioticQ36581675
Adriamycin and Daunorubicin Inhibition of Mutant T4 DNA PolymerasesQ37437883
Ansamycin biogenesis: studies on a novel rifamycin isolated from a mutant strain of Nocardia mediterraneiQ37457174
Effects of 5-azacytidine on nucleolar RNA and the preribosomal particles in Novikoff hepatoma cellsQ39319977
Cytogenetic effect of bleomycin on human leukocytes in vitroQ39334696
Antibiotics and nucleic acidsQ39866753
A clinical review of bleomycin--a new antineoplastic agentQ39868693
The effect of puromycin and cycloheximide on vacuole formation and exocytosis in Tetrahymena pyriformis GL-9Q39922976
Effect of cordycepin on the replication of type-c rna tumor virusesQ39937307
Action of cytochalasin D on cells of established lines. III. Zeiosis and movements at the cell surfaceQ39943261
Mode of action of zorbamycinQ40096635
Influence of template inactivators on the binding of DNA polymerase to DNA.Q40579440
Mechanism of action of gliotoxin: elimination of activity by sulfhydryl compoundsQ41028238
Microbial Production of Tenuazonic Acid AnaloguesQ41028925
Mode of action illudin S.Q41028991
Potentiation of 5-fluorouracil, chromomycin A3, and bleomycin by amphotericin B or polymyxin B in transformed fibroblastic cellsQ41029280
Inhibition of Mycoplasma pneumoniae by Actinomycin DQ41029938
Cytochalasin B. VI. Competitive inhibition of nucleoside transport by cultured Novikoff rat hepatoma cellsQ41154918
The differential effect of actinomycin D in normal and virus-transformed cellsQ41167876
Inhibition of phagocytosis and plasma membrane mobility of the cultivated macrophage by cytochalasin B. Role of subplasmalemmal microfilamentsQ41182472
The action of certain antibiotics on mitochondrial, erythrocyte and artificial phospholipid membranes. The role of induced proton permeabilityQ41853287
Variation of the supercoils in closed circular DNA by binding of antibiotics and drugs: Evidence for molecular models involving intercalationQ41937422
Selective release of lysosomal hydrolases from phagocytic cells by cytochalasin BQ41999302
Enhancement of rat liver uridine kinase activity by various metabolic inhibitorsQ42230617
Effect of phenylpyruvate on enzymes involved in fatty acid synthesis in rat brainQ42248288
The inhibition of nucleic acid synthesis by mycophenolic acidQ42934028
Inactivation of DNA-binding activity of repressor in extracts of lambda-lysogen treated with mitomycin C.Q43492021
Inhibition of RNA and DNA polymerase reactions by pluramycin AQ43501166
Antitumour Polysaccharide derived Chemically from Natural Glucan (Pachyman)Q43578768
Alteration of ribosomal precursor RNA in Novikoff hepatoma cells by 5-azacytidine. Studies on methylation of 45S and 32S RNA.Q43589911
Induction of local denaturation in DNA in vitro by phleomycin and caffeineQ43614566
Identification of ilicicolins with ascochlorin and LL-Z 1272.Q43654557
Distamycin: an inhibitor of DNA-dependent nucleic acid synthesisQ43679129
Mechanism of action of chromomycin A3. 3. On the binding of chromomycin A3 with DNA and physiochemical properties of the complexQ43693822
The effect of mitomycin C on deoxyribonucleic acid and messenger ribonucleic acid in Escherichia coliQ43704344
Localization and kinetics of formation of nuclear heterodisperse RNA, cytoplasmic heterodisperse RNA and polyribosome-associated messenger RNA in HeLa cellsQ43749259
Steffimycin B, a DNA binding agentQ43765050
Studies on the effect of distamycin A on the DNA dependent RNA polymerase systemQ43802463
Structure-activity relationships of the mitomycins and certain synthetic analogsQ43826364
Effects of the mycotoxin sporidesmin on swelling and respiration of liver mitochondriaQ43982308
Effects of alanosine on purine and pyrimidine synthesisQ44005247
Amplification of phleomycin induced death and DNA breakdown by caffeine in Escherichia coliQ44093160
5-Diazo-4-Oxo-L-Norvaline: Reactive Asparagine Analog with Biological SpecificityQ44171142
Puromycin effect on amino acid transport: differential rates of carrier protein turnoverQ44187506
The inhibition in vitro of DNA polymerase and RNA polymerases by daunomycin and adriamycinQ44227975
Chemotherapeutic properities of anthramycinQ44259950
Nucleic acid--specificity of bleomycinQ44296112
Aranoflavin, a new antibioticQ71601698
Reaction of anthramycin with deoxyribonucleic acidQ71623836
Effects of intraductal administration of prolactin, actinomycin D and cycloheximide on lipoprotein lipase activity in the mammary glands of pseudopregnant rabbitsQ71642057
Inhibition of RNA synthesis by actinomycin D: Characteristic dose-response of different RNA speciesQ71647340
Radioautographic study of RNA synthesis in normal and actinomycin D treated rat embryosQ71658777
Inhibition of transcription by pluramycin and bleomycinQ71726743
Binding of streptonigrin to DNAQ71730088
The inhibition of RNA and DNA polymerases by hedamycinQ71730090
Inhibition of amino acid and sugar transport by showdomycinQ71755968
The binding of actinomycin D to crab poly d(A-T)-poly d(T-A). ii. On the nature of the DNA binding siteQ71764430
Studies on Actinomyces tumemacerans strain INMI P-42 with particular reference to antibiotic productionQ71770989
Reversible interconversions of sterol-binding and sterol-nonbinding forms of filipin as determined by fluorimetric and light scattertin propertiesQ69647055
Inhibition of glucose transport in the human erythrocyte by cytochalasin BQ69647062
A new antibiotic, leucinostatin, derived from Penicillium lilacinumQ69665022
Biological activities of albonoursinQ69665026
Letter: The structure of reumycinQ69687743
A new antitumor antibiotic, kidamycin. IV. Pharmacokinetics of acetyl-kidamycinQ69687922
SR1768A, an antitumor antibiotic closely related to chromomycinQ69687936
D-glucosamine and L-citrulline, precursors in mitomycin biosynthesis by Streptomyces verticillatusQ69733168
Effects of chlorpromazine and actinomycin D on uptake and incorporation of certain amino acids, hypoxanthine and thymidine in cultures of human skin epithelial cellsQ69752499
Inhibition of palatal fusion in vitro by hadacidinQ69756966
Immunosuppression in Chickens by Aflatoxin ,Q69777261
Biosynthesis of the verrucarins and roridins. 1. The transformation of mevalonic acid into verrucarinic acid. Evidence for a hydrogen 1,2-shiftQ69811070
Chemical and biological characterization of succinyl neocarzinostatinQ69811325
Interaction of nogalamycin with DNAQ69813466
Physical and chemical characteristics and structure of carminomycin, a new antitumor antibioticQ69815307
Puromycin: a questionable drug for studying the mechanism of thyroid calorigenesis in vivoQ69815747
The mechanism of prumycin actionQ69817047
Antitumor antibiotics produced by Penicillium stipitatum ThomQ69819772
[Isolation and structural clarification of chlamydocin]Q69820601
The action of rifampicin on stabilized cell lines HEp-2 and HeLaQ69820805
The effects of some tetracycline derivates on Ehrlich ascites carcinoma and HeLa cells in vitroQ69821541
The specific inhibition of the DNA-directed RNA synthesis by rifamycinQ69830763
Effect of olivomycin and echinomycin on initiation and growth of RNA chains catalyzed by RNA polymeraseQ69859109
Interaction of the RNA Polymerase Inhibitor Chromomycin with DNA*Q69877680
The combined effects of bleomycin and sulfhydryl compounds on the thermal denaturation of DNAQ69878394
Effect of 9α-fluoroprednisolone and l-asparaginase on uridine incorporation into ribosomal RNA of P1798 lymphosarcomaQ69887927
Effect of actinomycin D and glucagon on glucose uptake by spheroplasts of E. coliQ69901869
Interaction of kanchanomycin with nucleic acids. III. Contrasts in the mechanisms of inhibition of ribonucleic acid and deoxyribonucleic acid polymerase reactionsQ69919117
Effects of bleomycin A2 on deoxyribonuclease, DNA polymerase and ligase reactionsQ69931249
A new actinomycin-like antibiotic produced by a mutant strain of Streptomyces indicusQ69957381
Actinomycin D inhibition of amino acid transport in Streptococcus faecalisQ69995541
Müller WE,+MULLER WE, Zahn RK:Action of bleomycin on programmed synthesis. Influence on enzymatic DNA, RNA and protein synthesisQ69998093
Effects of bleomycin on human and experimental squamous carcinomaQ69999012
Effects of bleomycin on Escherichia coli strains with various sensitivities to radiationsQ69999663
The mechanism of inhibition of protein synthesis by 5-azacytidine in HeLa cellsQ70004129
The antibiotic YA-56 complex: isolation, purification and physicochemical properties of the main componentsQ70010099
Letter: Chemical cleavage of bleomycin to bleomycinic acid and synthesis of new bleomycinsQ70010486
Letter: Chemistry of bleomycin. XI. The structures of the terminal aminesQ70010495
Inhibition of ribosomal ribonucleic acid maturation by 5-azacytidine and 8-azaguanine in Novikoff hepatoma cellsQ70015291
The effect of bleomycin on SV40 DNA: characteristics of bleomycin action which produces a single scission in a superhelical form of SV40 DNAQ70018626
Interactions of DNA with zorbamycin, phleomycin and bleomycin; ultraviolet absorption and circular dichroism measurementsQ70018629
Effects of bleomycin on PHA-stimulated lymphocytes and isolated hepatic nucleiQ70018633
Biosyntheses of new bleomycinsQ70020310
New antilymphoma L-asparaginase from Fusarium speciesQ70021452
Effects of bleomycin on cells in culture: a quantitative cytochemical studyQ70027744
Breakage of DNA-membrane complex by bleomycinQ70027977
Kundrymycin, a new tumor-inhibitory antibiotic. I. Culture taxonomy, fermentation and productionQ48807014
Differential mutagenicity of streptozotocin analogs of the carbohydrate moietyQ50230970
Relative biological activities of individual streptovaricins and streptovaricin acetatesQ50231713
A new antibacterial agent (U-20,661) isolated from a Streptomycete strainQ50249560
ENHANCED SUPPRESSION OF THE SECONDARY IMMUNE RESPONSE BY COMBINATION OF 6-MERCAPTOPURINE DUAZOMYCIN A'.Q52282629
Cytochemical evidence for RNA synthesis inhibition by fumagillinQ52479081
Transforming potential of the anticancer drug adriamycinQ53595533
Virally transformed cells and cytochalasin B. I. The effect of cytochalasin B on cytokinesis, karyokinesis and DNA synthesis in cells.Q53597096
The mechanism of action of aflatoxin B1 on protein synthesis: observations on malignant viral transformed and untransformed cells in culture.Q53600619
Comparison of the Antitumor Effect of Interferon and Interferon InducersQ53605870
Cytostatic activity of chlamydocin, a rapidly inactivated cyclic tetrapeptide.Q53688762
Catalysis of peptidyl transfer by human tonsil ribosomes and effects of some antibiotics.Q53709800
Significance of streptozotocin induced nicotinamide-adenine-dinucleotide (NAD) degradation in mouse pancreatic islets.Q53720022
Studies on the formation of transfer ribonucleic acid-ribosome complexes. 8. Survey of the effect of antibiotics of N-acetyl-phenylalanyl-puromycin formation: possible mechanism of chloramphenicol action.Q53732055
Interaction of phleomycin with soluble cytoplasmic proteins from HeLa S-3 cells.Q53737663
Inhibition of RNA synthesis in mitochondria by daunomycinQ53744030
Inhibition of post-UV irradiation growth in the dark of Tetrahymena pyriformis by caffeine and the oncogenic mycotoxin luteoskyrin.Q53754377
Mechanism of action of diketocoriolin B.Q53766011
Nucleoside antibiotics. Biosynthesis of arabonofuranosyladenine by Streptomyces antibioticus. 10Q53775462
Effect of daunomycin on HeLa cell nucleic acid synthesis.Q53796162
Mode of action of adriamycin on HeLa S-3 cells in vitroQ53806876
Synthesis of a C-nucleoside analog of the antibiotic cordycepin.Q53812426
[Effect of some cytostatic agents on DNA-synthesis in an oncogenic RNA virus].Q53815075
Interaction of daunomycin with meiotic chromosomes in Vicia fabaQ53838507
Cycloheximide induced in vivo modification of ornithine decarboxylase in Physarum polycephalumQ53848453
The biochemical mechanism of selective heat sensitivity of cancer cells. I. Studies on cellular respiration.Q53854986
Antiviral activity of L-asparaginase.Q53906026
Inhibition of rat-liver RNA polymerase in vitro by aflatoxin B1 in the presence of microsomal fraction.Q53914610
Influence of netropsin and distamycin A on the secondary structure and template activity of DNA.Q53950143
Isolation of 11 , 11' -dihydroxychaetocin from Verticillium tenereumQ53953799
Hedamycin and rubiflavin complexes with deoxyribonucleic acid and other polynucleotides.Q53982646
Inhibition of 3H-Thymidine Incorporation into Rat Liver Nuclei by E. coli L-AsparaginaseQ53985449
Effect of antitumour polysaccharides on the higher structure of serum protein.Q53990159
The effects of neonatal thymectomy on the antitumour activity of lentinan, carboxymethylpachymaran and zymosan, and their effects on various immune responsesQ54025631
Letter: A revised structure of vermiculine. A novel macrolide dilactone antibiotic from Penicillium vermiculatum.Q54059185
Effect of puromycin on DNA replication in Chinese hamster cells.Q54140946
Rifampicin inhibition of poly(dT)·Poly (A)-primed poly (A) synthesis by HeLa AMP polynucleotidylexotransferaseQ54172237
Effect of cordycepin on induction of tyrosine aminotransferase employing hepatoma cells in tissue culture.Q54196397
Studies on bredinin. I. Isolation, characterization and biological propertiesQ54244278
Crystalline L-leucine dehydrogenase.Q54283105
Conformative response of xanthosine 5'-phosphate aminase.Q54290437
Structure of the peptide antibiotic amphomycin.Q54304191
Effect of borrelidin on the threonyl-tRNA-synthetase activity and the regulation of threonine-biosynthetic enzymes in Saccharomyces cerivisiaeQ54305603
Phleomycin stimulation of thymidine triphosphate incorporation by animal cell nuclei.Q54327284
Effect of the antibiotic Borrelidin on the regulation of threonine biosynthetic enzymes in E.coliQ54333189
An electron-microscopic study on morphological changes of Staphylococcus aureus treated with spiramycinQ54394651
Studies on the formation of transfer ribonucleic acid-ribosome complexes. IX. Effect of antibiotics on translocation and peptide bond formation.Q54456784
Mode of action of tomaymycinQ54462646
Feedback inhibition of purine biosynthesis in ascites tumor cells by purine analogues.Q54465010
Distribution of mitomycin C-induced damage in human chromosomes with special reference to regions of repetitive DNA.Q54481966
Sensitivity of G1 phase of the mitotic cycle to chromosome aberrations induced by daunomycinQ72428141
Coriolin, a new Basidiomycetes antibioticQ72486810
Isolation and characterization of lymphomycinQ72486819
The effect of toyocamycin on cellular RNA synthesisQ72511576
Effect of 3′-deoxyadenosine and 3′-amino-3′-deoxyadenosine on the labelling of RNA sub-species in Ehrlich ascites tumor cellsQ72515208
Differential agar-diffusion bioassay for cytotoxic substancesQ72517354
Studies on micronuclei induced by mitomycin-C in the root cells of Vicia fabaQ72539885
Inhibition of protein synthesis in vitro by cycloheximide and related glutarimide antibioticsQ72622191
Effects of streptonigrin on nucleic acid metabolism of tissue culture cellsQ72659536
Discovery of inhibitory activity of tenuazonic acid for growth of human adenocarcinoma-1Q72726044
Actinomycin D: Inhibition of Respiration and GlycolysisQ72769972
Mass spectra of puromycin and some derivativesQ72894131
Mode of action of neocarzinostatin: inhibition of DNA synthesis and degradation of DNA in Sarcina luteaQ72905323
Leukemia. VI. Effect of amicetin on transplanted mouse leukemiaQ73629487
Effects of Sarcomycin on the Metabolism of Ehrlich Ascites Carcinoma CellsQ74212195
Intracellular transfer of nucelic acids in rat ascites hepatoma cellsQ76411463
INHIBITION OF THE SYNTHESIS OF PROTEIN IN INTACT ANIMALS BY ACETOXYCYCLOHEXIMIDE AND A METABOLIC DERANGEMENT CONCOMITANT WITH THIS BLOCKADEQ76584269
ACTINOMYCIN: CORRELATION OF STRUCTURE AND FUNCTION OF ITS COMPLEXES WITH PURINES AND DNAQ76612203
TUMOR INHIBITORY EFFECT OF L-ASPARAGINASE FROM ESCHERICHIA COLIQ76897401
Studies on the complex of distamycin a with calf thymus DNAQ77914388
Optical rotatory dispersion properties of nucleic acid complexes with the oligopeptide antibiotics distamycin A and netropsinQ77914628
The effect of the aminoacyl-4-aminohexosyl-cytosine group of antibiotics on ribosomal peptidyl transferaseQ77921525
Action of bleomycin on programmed synthesis. Influence on DNA and RNA nucleasesQ77921651
Effect of distamycin a on the structure and template activity of DNA in RNA - polymerase systemQ77922862
Interaction of Ac-Phe-tRNA with e. coli ribosomal subunits. 1. Sparsomycin-induced formation of a complex containing 50 S and 30 S subunits but not mRNAQ77922877
The inhibition of DNA-dependent RNA polymerase of E. coli by ShowdomycinQ77922903
Die Konstitution von Brefeldin AQ78233429
Die Struktur von Panepoxydon und verwandten PilzmetabolitenQ78233470
Three Chemically Related Metabolites of Streptomyces. II. Structural Studies1Q78328945
FUNGAL METABOLITES. THE STRUCTURES OF THE NOVEL SESQUITERPENOIDS ILLUDIN-S AND -MQ78398245
A NEW ANTITUMOR ANTIBIOTIC, KIDAMYCIN. IQ78418286
AGTINOMYGIN MONOLAGTONE. IIIQ78418351
Steffimycin B, a new member of the steffimycin family: isolation and characterization.Q78418463
A NEW ANTIBIOTIC, 1-(p-HYDROXYPHENYL)-2, 3-DIISOCYANO-4-(p-METHOXYPHENYL)-BUTA-1, 3-DIENE. IQ78438468
ISOLATION AND CHARACTERIZATION OF A NEW ANTIBIOTIC, NEOPLURAMYCINQ78438564
ANTIBIOTICS PRODUCED BY STREPTOMYCES. VIIIQ78438606
ON PHYSICO-CHEMICAL INTERACTIONS BETWEEN DAUNOMYCIN AND NUCLEIC ACIDSQ78522164
Possible utility of the Rous sarcoma for antitumor screeningQ78545145
Hadacidin, a New Growth-Inhibitory Substance in Human Tumor SystemsQ78941428
The mode of action of actinomycin DQ79046322
Carzinophilin in advanced solid cancerQ79277508
Actionmycin D inhibition of deoxyribonucleic acid-dependent synthesis of ribonucleic acidQ79397957
Effect of mitomycin C on mammalian cells in cultureQ79416872
Calvacin: A New Antitumor AgentQ80880710
Purine Metabolism in Tetrahymena and Its Relation to Malignant Cells in MiceQ81174173
Inhibition of ligase reaction by bleomycinQ93714996
Action of bleomycin on DNA and RNAQ93733024
Strand-scission of HeLa cell deoxyribonucleic acid by bleomycin in vitro and in vivoQ93733639
Inhibition of thymidylate synthetase by showdomycin and its 5′-phosphateQ44373808
Effect of rifampicin on bacteriophage PM2 biogenesisQ44412882
Interaction of some daunomycin derivatives with deoxyribonucleic acid and their biological activityQ44418610
Induction of a reversible G 1 block in human glia-like cells by cytochalasin BQ44438717
The cytogenetic effect of rubidomycin in vivo in ratsQ44472163
Identity of antibiotic P-42-1 elaborated by Actinomyces tumemacerans with kanchanomycin and albofungin.Q44483265
Inhibition of R-factor transfer and phage infection by requinomycinQ44509227
Bikaverin, an antibiotic fromGibberella fujikuroi, effective againstLeishmania brasiliensisQ44514095
Bleomycin, a selective inhibitor of DNA-dependent DNA polymerase from oncogenic RNA virusesQ44554878
Analysis of transcription in vitro using purine nucleotide analogsQ44576468
Limitation of nuclear division by protease inhibitors in cytochalasin-B-treated tumor cellsQ44605737
Effects of anticancer agents on the respiration of isolated mitochondria and tumor cellsQ44652420
Actinomycin mono-lactone, a metabolite of Streptomyces antibioticus 3720.Q44652744
Actinomycin D: inhibition of phospholipid synthesis in chick embryo cellsQ44733005
Inhibition of Rd/3 rat sarcoma by L-asparaginase alone and in combination with sodium para-amino-salicylateQ44752361
Biosynthesis of cytochalasins. II Building blocks of cytochalasun DQ44778766
Antiinfluenzal Effect of RugulosinQ44811173
Cellular binding of 3H-cytochalasin B.Q44812997
Influence of Temperature on the Action of Rifampicin on RNA Polymerase in Presence of DNAQ44848696
On the binding of aflatoxin B 1 and its metabolites to hepatic microsomesQ70034261
Effect of olivomycin on the induced synthesis of tyrosine aminotransferase and tryptophan oxygenase in rat liverQ70039603
Inhibition of DNA synthesis and chromosome aberrations in cultured ehrlich ascites tumor cells following treatment with luteoskyrinQ70118313
Effects of several tumor-inhibitory antibiotics on immunological responsesQ70120482
Metabolic products of microorganisms. Structure of cinerubine BQ70365975
The structure of minimycin, a novel carbon-linked nucleoside antibiotic related to -pseudouridineQ70395849
Effects of cytochalasin B on polymorphonuclear leucocyte locomotion, phagocytosis and glycolysisQ70439654
Inhibition of the phosphoribosylformylglycineamidine synthetase of ehrlich ascites tumor cells by glutamine analoguesQ70455608
Melinacidins 2, 3 and 4, new "3,6-epidithiadiketopiperazine" antibioticsQ70459499
Effects of anthramycin and actinomycin on RNA synthesis patterns in L1210 cellsQ70460528
Sporidesmins. 8. Ovine ill-thrift in Nova Scotia. 3. The characterisation of chetomin a toxic metabolite of Chaetomium cochliodes and Chaetomium globosumQ70463813
Interaction of the oligopeptide antibiotics netropsin and distamycin a with nucleic acidsQ70520658
Reversible binding of macromomycin, a macromolecular eptide antibiotic, to cell membranesQ70555560
The mechanisms of action of anti‐tumour polysaccharides. I. The effects of antilymphocyte serum on the anti‐tumour activity of lentinanQ70596327
Oxazinomycin, a new carbon-linked nucleoside antibioticQ70654946
Antitumor activity of cytochalasin DQ70710817
Total synthesis of antimycin A 3Q70710820
The mechanism of inhibition of tryptophan 2,3-dioxygenase by aquayamycinQ70715108
The ilicicolins, antibiotics from Cylindrocladium ilicicolaQ70731008
Isolation and characterization of a fungal vacuolation factor (bikaverin)Q70733964
Bikaverin and norbikaverin, benzoxanthentrione pigments of Gibberella fujikuroiQ70733970
Fusarenon-X, a toxic principle of Fusarium nivale — Culture filtrateQ71120410
Base Specificity in the Interaction of Polynucleotides with Antibiotic DrugsQ71157861
The effect of lysogenic induction with mitomycin C on the DNA and DNA polymerase of Escherichiacoli K12λQ71160835
Enhancement of catabolite repression by mitomycin C in the induced synthesis of β-galactosidaseQ71176110
Studies on a new pigment antibiotic, chrothiomycinQ71224302
Mitocromin: an antibiotic with antitumor activityQ71279336
Specificity of daunomycin in causing chromosome aberrations in human leukocytesQ71422162
Isolation and structure of the antibiotics Phomin and 5-dehydrophominQ71475279
Structure of mitiromycinQ71488704
Structure of pactamycinQ71494014
[Isolation and configuration of Chaetocin]Q71515182
Structure and chemistry of actinobolinQ71515231
Studies on a new antitumor antibiotic, largomycin. II. Isolation, purification and physicochemical propertiesQ71527132
Studies on a new antitumor antibiotic, largomycin. 3. Biological properties and antitumor activity of largomycin F-IIQ71527136
Selective inhibition of ribosomal RNA synthesis in HeLa cells by nogalamycin, a dA:dT binding antibioticQ71527642
Equimolecular reaction of showdomycn with thiolsQ71540071
Studies on the metabolites of Zygosporium masonii. I. Structure of zygosporin AQ71545264
The structure of bostrycinQ71552668
Actinomycin D: Effect on macromolecular synthesis in synchronized Tetrahymena pyriformisQ71569884
Alanylactinobolone. Basic hydrolysis product of the antibiotic actinbolinQ71579583
Effects of 9-aminoacridine on bacteriophage T4 deoxyribonucleic acid synthesisQ71585014
Kinetics of the in vitro inhibition of transcription by actinomycinQ71585026
Biological effects of anthramycin methyl ether. 3. Inhibition of erythropoiesisQ69467713
Cycloheximide enhanced porphyrin synthesis in chick embryo liver: Association with an increase in the hepatic glycine poolQ69538764
Stereochemistry and synthesis of the antileukemic agent botryodiplodinQ69576780
Interaction of nogalamycin with deoxyribonucleic acidQ69579877
Effect of cytochalasin B on epidermal cell migration in vitro*Q69581035
Synthesis of some rifamycin derivatives as inhibitors of an RNA-instructed DNA polymerase functionQ69602605
Inhibition of mitochondrial contraction by cytochalasin BQ69626784
Utilization of substrate analogs by mengovirus induced RNA polymeraseQ68592411
Dextrochrysin, a new antibioticQ68599703
Effects of neopluramycin on ascites tumors implanted in experimental animalsQ68622740
Cytochalasin B. I. Effect on cytokinesis of Novikoff hepatoma cellsQ68623413
Mitochondria and respiratory enzymes of L cells treated with actinomycin DQ68657297
Effect of phleomycin on the replication of mengovirus in novikoff hepatoma cellsQ68659644
Puromycin stimulation of rat liver ornithine decarboxylase activityQ68660195
Effect of cytochalasin B on lymphocyte stimulation induced by concanavalin A or periodateQ68668388
Effects of actinomycin D on purine ribonucleotide metabolism in Ehrlich ascites tumor cells in vitroQ68684718
Studies on plasma membranes. XXI. Inhibition of liver plasma membrane enzymes by tumour-promoting phorbolester, mitotic inhibitors and cytochalasin BQ68686760
DNA strand scission by the antitumor protein neocarzinostatinQ68697374
Improved methods for the study of drug effects on purine metabolism and their application to nebularine and 7-deazanebularineQ68700075
Cycloheximide inhibition of hypoxanthine transport cultured cellsQ68700771
Inhibition of nucleoside incorporation into HeLa cells by streptovaricinQ68751645
Comparative cytogenetic study after treatment of mouse spermatogonia with mitomycin CQ68777011
Rifamycin biosynthesis: further studies on origin of the ansa chain and chromophoreQ68795359
Rifamycins: an insight into biological activity based on structural investigationsQ68860475
Comparison of adriamycin with the DNA-adriamycin complex in chemotherapy of L1210 leukemiaQ68890416
Chromatographic analysis of neomycin. Isolation and identification of minor componentsQ68917330
Isolation of fatty acids from the mycelium ofPenicillium stipitatum thom and their effect on ehrlich ascites carcinoma cellsQ68925083
Isolation and characterization of a new antitumor antibiotic OS-3256-B from Streptomyces candidus var. azaticusQ68928507
Impulsecytophotometric studies on the effects of daunomycin on synchronised L-cellsQ68938311
Polyene antibiotic-sterol interactions in membranes of Acholeplasma laidlawii cells and lecithin liposomes. I. Specificity of the membrane permeability changes induced by the polyene antibioticsQ69139208
Vermiculine, a new antiprotozoal antibiotic from Penicillium vermiculatumQ69194794
Studies on the biological properties of polyene antibiotics: Comparison of other polyenes with filipin in their ability to interact specifically with sterolQ69223021
Survey of inhibitors in different steps of protein synthesis by mammalian ribosomesQ69235459
Actions of aurintricarboxylate, kasugamycin, and pactamycin on Escherichia coli polysomesQ69244810
Mutation by mitomycins in the ultraviolet light-sensitive mutant of Escherichia coliQ69252849
The trichodermin group of antibiotics, inhibitors of peptide bond formation by eukaryotic ribosomesQ69285235
Sparsomycin requirement for inhibiting peptide-bond formationQ69287284
Comparison of Escherichia coli and T3 RNA polymerases. Differential inhibition of transcription by various drugsQ69314275
On the Binding of Rifampicin to the DNA-Directed RNA Polymerase from Escherichia coliQ69316157
Therapy with Erwinia L-asparaginase in children with acute leukemia after anaphylaxis to E. coli L-asparaginaseQ69328212
Puromycin analogs. Ribosomal binding with diastereomeric carbocyclic puromycin analogsQ69349207
Limitation of transcription by puromycin or chloramphenicol in DNA-coupled systems from Escherichia coliQ69351183
(G-3H)gougerotin binding to ribosomes. Heterogeneity of eukaryotic ribosomesQ69351513
(3H)anisomycin binding to eukaryotic ribosomesQ69352408
Selective inhibition of initiation of globin synthesis by phenomycinQ69355644
The inhibition of RNA polymerase by daunomycinQ69355803
Different effects of rifampicin and streptolydigin on the control of RNA polymerase subunit synthesis in Escherichia coliQ69366966
Some chemical and biological characteristics of showdomycinQ69369380
Effects of aflatoxin B1 on human skin lipids metabolism — a site of action on 1-14C-acetate incroporationQ69379243
A new antitumor antibiotic, kidamycin. II. Experimental treatment of cancer with kidamycinQ69406188
Studies on tomaymycin, a new antibiotic. I. Isolation and properties of tomaymycinQ69406499
Interaction of daunomycin and its derivatives with DNAQ69451246
Studies on cellular adhesion in tissue culture *1XII. Some effects of cytochalasins and colchicineQ69451648
Metabolites of Nectria coccineaQ69452057
P407language of work or nameEnglishQ1860
P921main subjectantineoplastic antibioticsQ4381760
P304page(s)259-370
P577publication date1976-01-01
P1433published inAdvances in Applied MicrobiologyQ15753069
P1476titleCytotoxic and antitumor antibiotics produced by microorganisms
P478volume20

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