Differential effects of quinidine on the disposition of nifedipine, sparteine, and mephenytoin in humans

scientific article published on 01 November 1991

Differential effects of quinidine on the disposition of nifedipine, sparteine, and mephenytoin in humans is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1038/CLPT.1991.177
P698PubMed publication ID1934865

P2093author name stringG R Wilkinson
D D Breimer
J H Schellens
H H van der Wart
H Ghabrial
E N Bakker
P433issue5 Pt 1
P921main subjectnifedipineQ39111
P304page(s)520-528
P577publication date1991-11-01
P1433published inClinical Pharmacology & TherapeuticsQ1101529
P1476titleDifferential effects of quinidine on the disposition of nifedipine, sparteine, and mephenytoin in humans
P478volume50

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cites work (P2860)
Q35640730"Cocktail" approaches and strategies in drug development: valuable tool or flawed science?
Q34122414Antiarrhythmic agents: drug interactions of clinical significance
Q36720920Appropriate phenotyping procedures for drug metabolizing enzymes and transporters in humans and their simultaneous use in the "cocktail" approach
Q40648534Assessment of liver metabolic function. Clinical implications
Q77452375Clinical pharmacokinetics of nisoldipine coat-core
Q72280929Cytochrome P-450IID6 phenotyping in cancer patients: debrisoquin and dextromethorphan as probes
Q73185409Dietary salt increases first-pass elimination of oral quinidine
Q73228890Drug-drug interactions: effect of quinidine on nifedipine binding to human cytochrome P450 3A4
Q58817150Effect of liver disease on dose optimization
Q34296874Health risks of herbal remedies
Q44247783Human variability in CYP3A4 metabolism and CYP3A4-related uncertainty factors for risk assessment
Q73511084Inhibition of CYP2D6 by quinidine and its effects on the metabolism of cilostazol
Q36055046Inhibition of debrisoquine hydroxylation with quinidine in subjects with three or more functional CYP2D6 genes
Q34409085The disposition of fluoxetine but not sertraline is altered in poor metabolizers of debrisoquin
Q40929413Use of Multiple Probes to Assess Transporter- and Cytochrome P450-Mediated Drug-Drug Interaction Potential of the Pangenotypic HCV NS5A Inhibitor Velpatasvir
Q73846452Validation of the five-drug "Pittsburgh cocktail" approach for assessment of selective regulation of drug-metabolizing enzymes
Q30778435Which concentration of the inhibitor should be used to predict in vivo drug interactions from in vitro data?