| scholarly article | Q13442814 |
| P356 | DOI | 10.1126/SCIENCE.1546322 |
| P698 | PubMed publication ID | 1546322 |
| P2093 | author name string | R. I. Morimoto | |
| L. Sistonen | |||
| D. A. Jurivich | |||
| R. A. Kroes | |||
| P433 | issue | 5049 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | hot | Q28128222 |
| sodium | Q658 | ||
| salicylic acid | Q193572 | ||
| P304 | page(s) | 1243-1245 | |
| P577 | publication date | 1992-03-01 | |
| 1992-03-06 | |||
| P1433 | published in | Science | Q192864 |
| P1476 | title | Effect of sodium salicylate on the human heat shock response | |
| P478 | volume | 255 |
| Q28116048 | A heat shock-responsive domain of human HSF1 that regulates transcription activation domain function |
| Q37101773 | A randomised trial of salsalate for insulin resistance and cardiovascular risk factors in persons with abnormal glucose tolerance |
| Q58699959 | A role for RNA metabolism in inducing the heat shock response |
| Q35725164 | Acetyl salicylic acid protected against heat stress damage in chicken myocardial cells and may associate with induced Hsp27 expression |
| Q39883748 | Acteylcholinesterase inhibitor rivastigmine enhances cellular defenses in neuronal and macrophage-like cell lines |
| Q36489064 | Activation of heat shock and antioxidant responses by the natural product celastrol: transcriptional signatures of a thiol-targeted molecule. |
| Q36701209 | Activation of heat shock factor 2 during hemin-induced differentiation of human erythroleukemia cells |
| Q41783044 | Activation of heat-shock transcription factor 1 by hypertonic shock in 3T3 cells |
| Q34189878 | Activation of heat-shock transcription factor by graded reductions in renal ATP, in vivo, in the rat. |
| Q28118171 | Activation of human heat shock genes is accompanied by oligomerization, modification, and rapid translocation of heat shock transcription factor HSF1 |
| Q37099810 | Antiproliferative prostaglandins activate heat shock transcription factor |
| Q35104489 | Arachidonate is a potent modulator of human heat shock gene transcription |
| Q37214824 | Aspirin-induced heat stress resistance in chicken myocardial cells can be suppressed by BAPTA-AM in vitro. |
| Q73331292 | Attenuated stress responses in young and old human lymphocytes |
| Q34225580 | Binding of purified multiple antibiotic-resistance repressor protein (MarR) to mar operator sequences |
| Q41727005 | Biochemical pharmacology of nonsteroidal anti-inflammatory drugs |
| Q34405013 | Biological rationale for the use of DNA methyltransferase inhibitors as new strategy for modulation of tumor response to chemotherapy and radiation |
| Q34628984 | Celastrol, an oral heat shock activator, ameliorates multiple animal disease models of cell death |
| Q36777158 | Chaperones and proteases: cellular fold-controlling factors of proteins in neurodegenerative diseases and aging. |
| Q35942273 | Characterizing the role of Hsp90 in production of heat shock proteins in motor neurons reveals a suppressive effect of wild-type Hsf1. |
| Q28187916 | Constitutive and heat-shock induced expression of Hsp70 mRNA during chicken testicular development and regression |
| Q28193163 | Controlled expression of recombinant proteins in Physcomitrella patens by a conditional heat-shock promoter: a tool for plant research and biotechnology |
| Q28114898 | DAXX interacts with heat shock factor 1 during stress activation and enhances its transcriptional activity |
| Q35096762 | Dealing with misfolded proteins: examining the neuroprotective role of molecular chaperones in neurodegeneration. |
| Q36218100 | Dual control of heat shock response: involvement of a constitutive heat shock element-binding factor |
| Q36551052 | Dynamic protein-DNA architecture of a yeast heat shock promoter |
| Q30451201 | Effect of salicylate, bismuth, osmolytes, and tetracycline resistance on expression of fimbriae by Escherichia coli |
| Q39806745 | Enhanced expression of heat shock protein 70 (hsp70) and heat shock factor 1 (HSF1) activation in rheumatoid arthritis synovial tissue. Differential regulation of hsp70 expression and hsf1 activation in synovial fibroblasts by proinflammatory cytoki |
| Q72999278 | Enhanced intestinal expression of heat shock protein 70 in patients with inflammatory bowel diseases |
| Q28343991 | Enhanced protein denaturation in indomethacin-treated cells |
| Q52187113 | Enhancement of expression of stress proteins by agents that lower the levels of glutathione in cells. |
| Q42557067 | Enhancement of stress-induced synthesis of hsp27 and alpha B crystallin by modulators of the arachidonic acid cascade |
| Q36682442 | Expression of Heat Shock Protein 70 is Altered by Age and Diet at the Level of Transcription |
| Q40424855 | Expression of antisense hsp70 is a major determining factor in heat-induced cell death of P-19 carcinoma cells |
| Q27934207 | Glycogen synthase phosphatase interacts with heat shock factor to activate CUP1 gene transcription in Saccharomyces cerevisiae |
| Q34769955 | HSP-72 accelerated expression in mononuclear cells induced in vivo by acetyl salicylic acid can be reproduced in vitro when combined with H2O2. |
| Q35560213 | Heat shock and UV-B-induced DNA damage and mutagenesis in skin |
| Q31478868 | Heat shock and oxidative stress-induced exposure of hydrophobic protein domains as common signal in the induction of hsp68. |
| Q39998290 | Heat shock co-activates interleukin-8 transcription. |
| Q38333325 | Heat shock factor 1 mediates hemin-induced hsp70 gene transcription in K562 erythroleukemia cells |
| Q34131180 | Heat shock factor 2 is a stress-responsive mediator of neuronal migration defects in models of fetal alcohol syndrome |
| Q36660240 | Heat shock factor is required for growth at normal temperatures in the fission yeast Schizosaccharomyces pombe |
| Q36109403 | Heat shock factors: integrators of cell stress, development and lifespan. |
| Q37293193 | Heat shock induces the release of fibroblast growth factor 1 from NIH 3T3 cells |
| Q36283450 | Heat shock protein 70: roles in multiple sclerosis |
| Q35545091 | Heat shock proteins as emerging therapeutic targets |
| Q37411519 | Heat shock proteins in diabetes and wound healing |
| Q34421860 | Heat shock proteins in the photobiology of human skin |
| Q27026884 | Heat shock transcription factor 1 as a therapeutic target in neurodegenerative diseases |
| Q36671824 | Heat shock transcription factor activates yeast metallothionein gene expression in response to heat and glucose starvation via distinct signalling pathways |
| Q33230457 | Heat shock-independent induction of multidrug resistance by heat shock factor 1. |
| Q80081976 | Heat stress-induced H(2)O (2) is required for effective expression of heat shock genes in Arabidopsis |
| Q64965757 | Heat stress-induced renal damage in poultry and the protective effects of HSP60 and HSP47. |
| Q70992088 | Heat-inducible expression system for a foreign gene in cultured tobacco cells using the HSP18.2 promoter of Arabidopsis thaliana |
| Q35913988 | Hsp70 accumulation in chondrocytic cells exposed to high continuous hydrostatic pressure coincides with mRNA stabilization rather than transcriptional activation |
| Q36700599 | Hyperosmotic stress response: comparison with other cellular stresses |
| Q39807933 | Ibuprofen inhibits cystic fibrosis transmembrane conductance regulator-mediated Cl- secretion |
| Q36567258 | In vivo growth of a murine lymphoma cell line alters regulation of expression of HSP72. |
| Q34139568 | Increased temperature and protein oxidation lead to HSP72 mRNA and protein accumulation in the in vivo exercised rat heart |
| Q55475727 | Induction of Hsp68 by oxidative stress involves the lipoxygenase pathway in C6 rat glioma cells. |
| Q42543272 | Induction of the DNA-binding and transcriptional activities of heat shock factor 1 is uncoupled in Xenopus oocytes |
| Q41186088 | Inhibition of HSP70 expression by calcium ionophore A23187 in human cells. An effect independent of the acquisition of DNA-binding activity by the heat shock transcription factor. |
| Q37730945 | Inhibition of activator protein 1 activity and neoplastic transformation by aspirin |
| Q33997775 | Inhibition of cytokine gene expression by sodium salicylate in a macrophage cell line through an NF-kappaB-independent mechanism. |
| Q77620716 | Inhibition of heat-shock protein 70 induction in intestinal cells overexpressing cyclooxygenase 2 |
| Q42471760 | Inhibition of mast cell-dependent anaphylaxis by sodium salicylate |
| Q95441089 | Inhibition of wound-induced accumulation of allene oxide synthase transcripts in flax leaves by aspirin and salicylic acid |
| Q36666939 | Interaction between heat shock factor and hsp70 is insufficient to suppress induction of DNA-binding activity in vivo |
| Q35802653 | Interference of transcriptional activation by the antineoplastic drug ecteinascidin-743. |
| Q39574298 | Intramolecular repression of mouse heat shock factor 1. |
| Q38305122 | Mechanism of quercetin-induced suppression and delay of heat shock gene expression and thermotolerance development in HT-29 cells |
| Q26741834 | Mechanisms of Hsp90 regulation |
| Q36738131 | Modes of action of aspirin-like drugs: salicylates inhibit erk activation and integrin-dependent neutrophil adhesion. |
| Q34271149 | Modulation of Drosophila heat shock transcription factor activity by the molecular chaperone DROJ1. |
| Q71830180 | Modulation of HSP68 gene expression after heat shock in thermosensitized and thermotolerant cells is not solely regulated by binding of HSF to HSE |
| Q36700530 | Modulation of heat shock factors accompanies salicylic acid-mediated potentiation of Hsp70 in tomato seedlings |
| Q42472992 | Modulation of human heat shock factor trimerization by the linker domain |
| Q36560927 | Modulation of thermal induction of hsp70 expression by Ku autoantigen or its individual subunits |
| Q42044806 | Modulation of transcription factor NF-kappaB by enantiomers of the nonsteroidal drug ibuprofen |
| Q39292455 | Molecular Chaperone Accumulation in Cancer and Decrease in Alzheimer's Disease: The Potential Roles of HSF1. |
| Q41064214 | Molecular chaperones and disease |
| Q24606489 | Molecular chaperones as HSF1-specific transcriptional repressors |
| Q38729074 | Molecular mechanism of thermosensory function of human heat shock transcription factor Hsf1. |
| Q90707043 | Multifactorial Attenuation of the Murine Heat Shock Response With Age |
| Q33886554 | Multiple functions of Drosophila heat shock transcription factor in vivo |
| Q36553698 | Multiple layers of regulation of human heat shock transcription factor 1. |
| Q35018012 | Multisite phosphorylation provides sophisticated regulation of transcription factors |
| Q24310850 | Negative regulation of the heat shock transcriptional response by HSBP1 |
| Q34020316 | Nonsteroidal anti-inflammatory drugs differentially affect the heat shock response in cultured spinal cord cells |
| Q24311729 | Novel testis-specific protein that interacts with heat shock factor 2 |
| Q33716872 | On mechanisms that control heat shock transcription factor activity in metazoan cells |
| Q34036459 | Pharmacological modulation of heat shock factor 1 by antiinflammatory drugs results in protection against stress-induced cellular damage |
| Q24294328 | Phosphorylation of HSF1 by MAPK-activated protein kinase 2 on serine 121, inhibits transcriptional activity and promotes HSP90 binding |
| Q28343736 | Phosphorylation of serine 230 promotes inducible transcriptional activity of heat shock factor 1 |
| Q34124352 | Plant stress hormones suppress the proliferation and induce apoptosis in human cancer cells |
| Q47819460 | Plants contain a novel multi-member class of heat shock factors without transcriptional activator potential |
| Q73228846 | Polyunsaturated fatty acids enhance the heat induced stress response in rainbow trout (Oncorhynchus mykiss) leukocytes |
| Q35023242 | Postinsult treatment with lithium reduces brain damage and facilitates neurological recovery in a rat ischemia/reperfusion model |
| Q72336778 | Potential involvement of a constitutive heat shock element binding factor in the regulation of chemical stress-induced hsp70 gene expression |
| Q24290312 | Potential targets for HSF1 within the preinitiation complex |
| Q34057831 | Prostaglandin E2 potentiates heat shock-induced heat shock protein 72 expression in A549 cells |
| Q43884437 | Protection against heat stress-induced oxidative damage in Arabidopsis involves calcium, abscisic acid, ethylene, and salicylic acid |
| Q36109387 | Protein Homeostasis in Models of Aging and Age-Related Conformational Disease |
| Q27003283 | Protein homeostasis as a therapeutic target for diseases of protein conformation |
| Q29614783 | Proteotoxic stress and inducible chaperone networks in neurodegenerative disease and aging |
| Q35964069 | Redox regulation of mammalian heat shock factor 1 is essential for Hsp gene activation and protection from stress |
| Q36564348 | Regulation of Drosophila heat shock factor trimerization: global sequence requirements and independence of nuclear localization |
| Q42146382 | Regulatory Mechanisms of Hsp90. |
| Q36567657 | Repression of the heat shock factor 1 transcriptional activation domain is modulated by constitutive phosphorylation |
| Q28473241 | Riluzole increases the amount of latent HSF1 for an amplified heat shock response and cytoprotection |
| Q36555704 | Role of chromatin and Xenopus laevis heat shock transcription factor in regulation of transcription from the X. laevis hsp70 promoter in vivo |
| Q43798440 | Role of cyclopentenone prostaglandins in rat carrageenin pleurisy |
| Q34027442 | Salicylate (salsalate) in patients with type 2 diabetes: a randomized trial |
| Q38290333 | Salicylate Triggers Heat Shock Factor Differently than Heat |
| Q40930844 | Salicylate-enhanced activation of transcription factors induced by interferon-gamma |
| Q27469944 | Salicylates inhibit flavivirus replication independently of blocking nuclear factor kappa B activation |
| Q45047581 | Salicylic acid-mediated potentiation of Hsp70 induction correlates with reduced apoptosis in tobacco protoplasts |
| Q29040995 | Sensing stress and responding to stress |
| Q45867307 | Sensitization of tumor cells to fas killing through overexpression of heat-shock transcription factor 1. |
| Q35801881 | Small molecule activators of the heat shock response and neuroprotection from stroke |
| Q39760026 | Specific induction of the 70-kD heat stress proteins by the tyrosine kinase inhibitor herbimycin-A protects rat neonatal cardiomyocytes. A new pharmacological route to stress protein expression? |
| Q40462908 | Stress Proteins: The Exercise Response |
| Q77318502 | Stress-inducible responses and heat shock proteins: new pharmacologic targets for cytoprotection |
| Q34340811 | Suppression of heat-induced hsp70 expression by the 70-kDa subunit of the human Ku autoantigen |
| Q36438422 | Suppressive effects of anti-inflammatory agents on human endothelial cell activation and induction of heat shock proteins. |
| Q36731446 | The association of Hsp90 expression induced by aspirin with anti-stress damage in chicken myocardial cells. |
| Q40016863 | The carboxyl-terminal transactivation domain of heat shock factor 1 is negatively regulated and stress responsive |
| Q33970976 | The effect of salsalate on biochemical factors and endothelial dysfunction of prediabetic patients: A randomized clinical trial |
| Q34089046 | The effects of salicylate on bacteria |
| Q35111527 | The effects of salsalate on glycemic control in patients with type 2 diabetes: a randomized trial |
| Q38341897 | The heat-shock transcription factor HSF1 is rapidly activated by either hyper- or hypo-osmotic stress in mammalian cells |
| Q28281884 | The human heat shock protein hsp70 interacts with HSF, the transcription factor that regulates heat shock gene expression |
| Q40424772 | The myocardial heat shock response following sodium salicylate treatment |
| Q73101250 | The phorbol ester 12-O-tetradecanoylphorbol 13-acetate enhances the heat-induced stress response |
| Q36557308 | The regulatory domain of human heat shock factor 1 is sufficient to sense heat stress |
| Q26775973 | The wonderous chaperones: A highlight on therapeutics of cancer and potentially malignant disorders |
| Q34713183 | The yeast heat shock transcription factor changes conformation in response to superoxide and temperature |
| Q47941159 | Therapeutic applications of heat shock proteins |
| Q35581498 | Therapeutic approaches to target inflammation in type 2 diabetes |
| Q35804087 | Thermal stress and the disruption of redox-sensitive signalling and transcription factor activation: possible role in radiosensitization |
| Q35813289 | Transcriptional regulation of the metazoan stress protein response |
| Q29617184 | Type 2 diabetes as an inflammatory disease |
| Q33889535 | Vascular heat shock protein expression in response to stress. Endocrine and autonomic regulation of this age-dependent response |
| Q34506792 | Yeast superoxide dismutase mutants reveal a pro-oxidant action of weak organic acid food preservatives |
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