Endogenous prostaglandin endoperoxides and prostacyclin modulate the thrombolytic activity of tissue plasminogen activator. Effects of simultaneous inhibition of thromboxane A2 synthase and blockade of thromboxane A2/prostaglandin H2 receptors in a

scientific article published on 01 October 1990

Endogenous prostaglandin endoperoxides and prostacyclin modulate the thrombolytic activity of tissue plasminogen activator. Effects of simultaneous inhibition of thromboxane A2 synthase and blockade of thromboxane A2/prostaglandin H2 receptors in a is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1172/JCI114813
P932PMC publication ID296837
P698PubMed publication ID2145320

P2093author name stringJ McNatt
J T Willerson
L M Buja
P Golino
S K Yao
M Rosolowsky
F De Clerck
P2860cites workIsolation and Structure of Two Prostaglandin Endoperoxides That Cause Platelet AggregationQ28622645
Coronary thrombolysis with recombinant human tissue-type plasminogen activator: a prospective, randomized, placebo-controlled trialQ34258431
Unidirectional transfer of prostaglandin endoperoxides between platelets and endothelial cellsQ34608006
Application of imidazole as a selective inhibitor thromboxane synthetase in human plateletsQ35020372
Prostaglandin endoperoxides modulate the response to thromboxane synthase inhibition during coronary thrombosisQ35593380
Monoclonal antibody against the platelet glycoprotein (GP) IIb/IIIa receptor prevents coronary artery reocclusion after reperfusion with recombinant tissue-type plasminogen activator in dogsQ35812008
Platelets interact with fibrin only after activationQ36488574
Synthesis of prostacyclin from platelet-derived endoperoxides by cultured human endothelial cellsQ37024612
Specific platelet mediators and unstable coronary artery lesions. Experimental evidence and potential clinical implicationsQ38648794
The biochemical pharmacology of thromboxane synthase inhibition in man.Q39834369
Thromboxane a2: biosynthesis and effects on plateletsQ40113741
Endogenous prostacyclin biosynthesis and platelet function during selective inhibition of thromboxane synthase in man.Q40682170
Enhancement of thrombolysis with tissue-type plasminogen activator by pretreatment with heparinQ41380863
Continued incorporation of circulating radiolabeled fibrinogen into preformed coronary artery thrombiQ44373063
Urinary excretion of prostaglandin E2, prostaglandin F2 alpha, and thromboxane B2 in normotensive and hypertensive subjects on varying sodium intakesQ46854085
Simultaneous administration of thromboxane A2- and serotonin S2-receptor antagonists markedly enhances thrombolysis and prevents or delays reocclusion after tissue-type plasminogen activator in a canine model of coronary thrombosis.Q54112049
Mediation of reocclusion by thromboxane A2 and serotonin after thrombolysis with tissue-type plasminogen activator in a canine preparation of coronary thrombosis.Q54127127
SQ 22536, an adenylate-cyclase inhibitor, prevents the antiplatelet effect of dazoxiben, a thromboxane-synthetase inhibitorQ58412227
Radioimmunoassay of Prostaglandins Fα, E1and E2in Human PlasmaQ67314548
Arterial walls generate from prostaglandin endoperoxides a substance (prostaglandin X) which relaxes strips of mesenteric and coeliac ateries and inhibits platelet aggregationQ68220963
R 68 070: thromboxane A2 synthetase inhibition and thromboxane A2/prostaglandin endoperoxide receptor blockade combined in one molecule--I. Biochemical profile in vitroQ69352638
Iliac artery mural thrombus formation. Effect of antiplatelet therapy on 111In-platelet deposition in baboonsQ69635954
Randomised trial of intravenous recombinant tissue-type plasminogen activator versus intravenous streptokinase in acute myocardial infarction. Report from the European Cooperative Study Group for Recombinant Tissue-type Plasminogen ActivatorQ69859494
Double-blind randomised trial of intravenous tissue-type plasminogen activator versus placebo in acute myocardial infarctionQ69872060
Thromboxane synthase inhibition potentiates washed platelet activation by endogenous and exogenous arachidonic acidQ69944964
Comparison of the interactions of fibrinogen and soluble fibrin with washed rabbit platelets stimulated with ADPQ69957246
Intravenous recombinant tissue-type plasminogen activator in patients with acute myocardial infarction: a report from the NHLBI thrombolysis in myocardial infarction trialQ70275606
The influence of selective thromboxane synthetase inhibition with a novel imidazole derivative, UK-38,485, on prostanoid formation in manQ70280909
The effect of intravenous thrombolytic therapy on left ventricular function: a report on tissue-type plasminogen activator and streptokinase from the Thrombolysis in Myocardial Infarction (TIMI Phase I) trialQ70331348
Rapid and sustained coronary artery recanalization with combined bolus injection of recombinant tissue-type plasminogen activator and monoclonal antiplatelet GPIIb/IIIa antibody in a canine preparationQ70376888
Inhibition of platelet thromboxane synthesis by 7-(1-imidazolyl) heptanoic acid: dissociation from inhibition of aggregationQ71592711
Endogenous prostacyclin contributes to the efficacy of a thromboxane synthetase inhibitor for preventing coronary artery thrombosisQ72909332
R 68 070: thromboxane A2 synthetase inhibition and thromboxane A2/prostaglandin endoperoxide receptor blockade combined in one molecule--II. Pharmacological effects in vivo and ex vivoQ93514266
P433issue4
P407language of work or nameEnglishQ1860
P921main subjectthrombolysisQ1931577
plasminogenQ107129060
P304page(s)1095-1102
P577publication date1990-10-01
P1433published inJournal of Clinical InvestigationQ3186904
P1476titleEndogenous prostaglandin endoperoxides and prostacyclin modulate the thrombolytic activity of tissue plasminogen activator. Effects of simultaneous inhibition of thromboxane A2 synthase and blockade of thromboxane A2/prostaglandin H2 receptors in a canine model of coronary thrombosis
P478volume86

Reverse relations

cites work (P2860)
Q35359038Advances in thrombolytic therapy
Q40432300Antiplatelet drugs. A comparative review
Q71326842Experimental studies on preventive effects of API0134 on vessel reocclusion after thrombolysis
Q35583996Glycoprotein IIb/IIIa Receptor Antagonists in the Treatment of Acute ST Elevation MI: From Hypotheses to Unexpected Recent Observations
Q48837287James Thornton Willerson, MD: a conversation with the editor. Interview by William Clifford Roberts
Q50949282Regulation of Coronary Blood Flow.
Q35873802Thromboxane synthase inhibitors and receptor antagonists