Pharmacokinetic interaction between cyclosporin and diltiazem

scientific article published on 01 January 1990

Pharmacokinetic interaction between cyclosporin and diltiazem is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1007/BF00315023
P698PubMed publication ID2340843

P2093author name stringK Wagner
W Weber
J Brockmöller
H H Neumayer
I Roots
G Heinemeyer
H Kewitz
P2860cites workCyclosporine drug interactions: a reviewQ39688566
Clinical pharmacokinetics of cyclosporinQ39729593
Role of calcium in pathogenesis of acute renal failureQ39731204
Trough levels and concentration time curves of cyclosporine in patients undergoing renal transplantationQ41293301
On the dose dependency of cyclosporin A absorption and disposition in healthy volunteersQ42655150
Cyclosporin-verapamil interactionQ43229099
Metabolism of cyclosporin A. IV. Purification and identification of the rifampicin-inducible human liver cytochrome P-450 (cyclosporin A oxidase) as a product of P450IIIA gene subfamilyQ43422277
Inhibition of hepatic microsomal drug metabolism by the calcium channel blockers diltiazem and verapamilQ49039298
Noncompartmental determination of the steady-state volume of distribution for any mode of administration.Q52724350
Standardization of symbols in clinical pharmacologyQ68021709
Prevention of posttransplant acute tubular necrosis by the calcium antagonist diltiazem: a prospective randomized studyQ68209396
Measurement of cyclosporin A and of four metabolites in whole blood by high-performance liquid chromatographyQ68963439
Prevention of delayed graft function in cadaver kidney transplants by diltiazem: outcome of two prospective, randomized clinical trialsQ69030886
Immunosuppressive properties of cyclosporin metabolitesQ69368328
Cyclosporin drug monitoring: comparison of four immunoassays and HPLCQ69503922
Cyclosporin. Pharmacokinetics and metabolismQ69555925
Diltiazem treatment impairs hepatic drug oxidation: studies of antipyrineQ69567235
Biotransformation and distribution in blood of cyclosporine and its metabolitesQ69677371
Nephrotoxic and immunosuppressive potentials of cyclosporine metabolites in ratsQ69677381
Prevention of delayed graft function in cadaver kidney transplants by diltiazemQ69873550
Cyclosporin-diltiazem interactionQ69880635
Influence of diltiazem on cyclosporin clearanceQ69882360
Nicardipine increases cyclosporin blood levelsQ69882455
Diltiazem and economic use of cyclosporinQ69886129
In vitro immunosuppressive properties of cyclosporine metabolitesQ70020765
Anaphylactic reaction and cardiopulmonary arrest following intravenous cyclosporineQ70055582
A program for non-linear regression analysis to be used on desk-top computersQ70823942
A Radioimmunoassay to Measure Cyclosporin a in Plasma and Serum SamplesQ70946075
P433issue3
P921main subjectpharmacokineticsQ323936
P304page(s)237-242
P577publication date1990-01-01
P1433published inEuropean Journal of Clinical PharmacologyQ1376707
P1476titlePharmacokinetic interaction between cyclosporin and diltiazem
P478volume38

Reverse relations

cites work (P2860)
Q70555092A controlled, double-blind, randomized trial of verapamil and cyclosporine in cadaver renal transplant patients
Q73881251A randomized trial comparing cyclosporine induction with sequential therapy in renal transplant recipients
Q35846658Alterations in cyclosporin A pharmacokinetics and metabolism during treatment with St John's wort in renal transplant patients
Q40648534Assessment of liver metabolic function. Clinical implications
Q36699356Calcium Antagonists in Patients with Heart Failure
Q35166632Clinical outcomes and management of mechanism-based inhibition of cytochrome P450 3A4.
Q41676632Diltiazem retards the metabolism of oral prednisone with effects on T-cell markers
Q35709872Drug therapy in transplant recipients: special considerations in the elderly with comorbid conditions
Q42545396Effect of diltiazem on concentration of cyclosporin metabolites in Sandimmune and Neoral treated kidney transplant patients
Q36053886Enhanced cholesterol reduction by simvastatin in diltiazem-treated patients
Q45262401Evaluation of hepatic function using the pharmacokinetics of a therapeutically administered drug. Application to the immunosuppressant cyclosporin
Q36055276Intravenous diltiazem and CYP3A-mediated metabolism
Q71835960Is the beneficial effect of calcium channel blockers against cyclosporine A toxicity related to a restoration of ATP synthesis?
Q77449564Is there a beneficial effect of the calcium channel blocker diltiazem on cyclosporine A nephrotoxicity in rats?
Q36068699Mechanism-based inhibition of cytochrome P450 3A4 by therapeutic drugs.
Q38018027Pharmacokinetic drug interactions with cyclosporin (Part II).
Q71674668Pharmacokinetic interaction between diltiazem and nortriptyline
Q67575638Pharmacokinetics of cyclosporine in hyperlipidaemic long-term survivors of heart transplantation. Lack of interaction with the lipid-lowering agent, fenofibrate
Q77495508The interaction of diltiazem with lovastatin and pravastatin
Q41478142The use of other drugs to allow a lower dosage of cyclosporin to be used. Therapeutic and pharmacoeconomic considerations
Q34345648Trough concentrations of cyclosporine in blood following administration with grapefruit juice

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