| scholarly article | Q13442814 |
| P356 | DOI | 10.1126/SCIENCE.2540528 |
| P698 | PubMed publication ID | 2540528 |
| P50 | author | Carl H. June | Q19277113 |
| P2093 | author name string | C B Thompson | |
| J A Ledbetter | |||
| G Stella | |||
| T Lindstein | |||
| P433 | issue | 4902 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | T cell activation | Q14863969 |
| P304 | page(s) | 339-343 | |
| P577 | publication date | 1989-04-01 | |
| P1433 | published in | Science | Q192864 |
| P1476 | title | Regulation of lymphokine messenger RNA stability by a surface-mediated T cell activation pathway | |
| P478 | volume | 244 |
| Q35148700 | A Constitutive Decay Element Promotes Tumor Necrosis Factor Alpha mRNA Degradation via an AU-Rich Element-Independent Pathway |
| Q47683142 | A Urokinase Receptor mRNA Binding Protein–mRNA Interaction Regulates Receptor Expression and Function in Human Pleural Mesothelioma Cells |
| Q34591732 | A binding factor for interleukin 2 mRNA. |
| Q39722619 | A broader role for AU-rich element-mediated mRNA turnover revealed by a new transcriptional pulse strategy |
| Q28145380 | A cellular calculus for signal integration by T cells |
| Q40641379 | A conditionally replicating adenovirus targeted to tumor cells through activated RAS/P-MAPK-selective mRNA stabilization. |
| Q38343270 | A cytidine deaminase expressed in the post-infective L3 stage of the filarial nematode, Brugia pahangi, has a novel RNA-binding activity |
| Q35925759 | A cytokine mRNA-destabilizing element that is structurally and functionally distinct from A+U-rich elements. |
| Q37349310 | A dynamic assembly of diverse transcription factors integrates activation and cell-type information for interleukin 2 gene regulation |
| Q34103699 | A split active site couples cap recognition by Dcp2 to activation |
| Q48019785 | A urokinase receptor mRNA binding protein from rabbit lung fibroblasts and mesothelial cells |
| Q24537360 | AMP-activated kinase regulates cytoplasmic HuR. |
| Q37636349 | AP-1 transcriptional activity requires both T-cell receptor-mediated and co-stimulatory signals in primary T lymphocytes. |
| Q24609390 | ARED: human AU-rich element-containing mRNA database reveals an unexpectedly diverse functional repertoire of encoded proteins |
| Q24606621 | AU-rich elements target small nuclear RNAs as well as mRNAs for rapid degradation |
| Q29547896 | AU-rich elements: characterization and importance in mRNA degradation |
| Q38460505 | Abatacept for lupus nephritis: Alternative definitions of complete response support conflicting conclusions |
| Q40710603 | Accessory cell-derived signals required for T cell activation |
| Q58882243 | Accumulation of Sequence-specific RNA-binding Proteins in the Cytosol of Activated T Cells Undergoing RNA Degradation and Apoptosis |
| Q68084399 | Activated but not resting T cells or thymocytes express colony-stimulating factor 1 mRNA without co-expressing c-fms mRNA |
| Q58620124 | Activation and expansion of tumour-infiltrating lymphocytes by anti-CD3 and anti-CD28 monoclonal antibodies |
| Q52058506 | Activation of CD4+ T cells by delivery of the B7 costimulatory signal on bystander antigen-presenting cells (trans-costimulation). |
| Q37275008 | Activation of human peripheral blood T lymphocytes by pharmacological induction of protein-tyrosine phosphorylation |
| Q36230977 | Activation-induced death by apoptosis in CD4+ T cells from human immunodeficiency virus-infected asymptomatic individuals |
| Q37169526 | Adenosine deaminase modulation of telomerase activity and replicative senescence in human CD8 T lymphocytes |
| Q52050831 | Age-related defects in CD2 receptor-induced activation in human T-cell subsets |
| Q56909311 | Alloantigen presentation by B cells: analysis of the requirement for B-cell activation |
| Q54195267 | Altered gene transcription after burn injury results in depressed T-lymphocyte activation |
| Q36691707 | An A + U-rich element RNA-binding factor regulates c-myc mRNA stability in vitro |
| Q38011360 | An Emerging Role of RNA-Binding Proteins as Multifunctional Regulators of Lymphocyte Development and Function |
| Q40404625 | An RNasin-resistant ribonuclease selective for interleukin 2 mRNA. |
| Q34014654 | An enigmatic tail of CD28 signaling |
| Q35834615 | An essential role for nuclear factor kappaB in promoting double positive thymocyte apoptosis |
| Q38334932 | An inducible cytoplasmic factor (AU-B) binds selectively to AUUUA multimers in the 3' untranslated region of lymphokine mRNA |
| Q36407406 | Antagonistic functions of tetradecanoyl phorbol acetate-inducible-sequence 11b and HuR in the hormonal regulation of vascular endothelial growth factor messenger ribonucleic acid stability by adrenocorticotropin. |
| Q34146304 | Anti-tumor necrosis factor modulates anti-CD3-triggered T cell cytokine gene expression in vivo |
| Q36231117 | Antibody and B7/BB1-mediated ligation of the CD28 receptor induces tyrosine phosphorylation in human T cells |
| Q72997029 | Antigen presentation by autoreactive proteolipid protein peptide-specific T cell clones from chronic progressive multiple sclerosis patients: roles of co-stimulatory B7 molecules and IL-12 |
| Q35353501 | Antigen presentation in virus infection |
| Q55241240 | Antigen-presenting human T cells and antigen-presenting B cells induce a similar cytokine profile in specific T cell clones. |
| Q33937471 | Antigen-specific regulation of T cell-mediated cytokine production |
| Q35637379 | Antigen‐specific blocking of CD4‐Specific immunological synapse formation using BPI and current therapies for autoimmune diseases |
| Q47705496 | Antioxidants stimulate transcriptional activation of the c-fos gene by multiple pathways in human fetal lung fibroblasts (WI-38). |
| Q77090329 | Association of cytokine polymorphic inheritance and in vitro cytokine production in anti-CD3/CD28-stimulated peripheral blood lymphocytes |
| Q36935749 | At the bench: preclinical rationale for CTLA-4 and PD-1 blockade as cancer immunotherapy |
| Q37557689 | B-cell surface antigen B7 provides a costimulatory signal that induces T cells to proliferate and secrete interleukin 2. |
| Q36362561 | B7 but not intercellular adhesion molecule-1 costimulation prevents the induction of human alloantigen-specific tolerance |
| Q56909144 | B7-1 synergizes with interleukin-12 in interleukin-2 receptor alpha expression by mouse T helper 1 clones |
| Q24291070 | B7-DC, a new dendritic cell molecule with potent costimulatory properties for T cells |
| Q42476822 | B7/BB-1 antigen expression on adult human microglia studied in vitro and in situ |
| Q41588339 | B7/BB1, the ligand for CD28, is expressed on repeatedly activated human T cells in vitro. |
| Q62733759 | B7/CD28 but not LFA-3/CD2 interactions can provide 'third-party' co-stimulation for human T-cell activation |
| Q34638095 | B7/CD28 in Central Tolerance: Costimulation Promotes Maturation of Regulatory T Cell Precursors and Prevents Their Clonal Deletion |
| Q24522565 | BAZF, a Novel Bcl6 Homolog, Functions as a Transcriptional Repressor |
| Q28117267 | BRF1 protein turnover and mRNA decay activity are regulated by protein kinase B at the same phosphorylation sites |
| Q59019634 | Between B cells and T cells |
| Q41826137 | Binding of a protein to an AU-rich domain of tumour necrosis factor alpha mRNA as a 35 kDa complex and its regulation in primary rat astrocytes |
| Q34591923 | Binding of the B cell activation antigen B7 to CD28 costimulates T cell proliferation and interleukin 2 mRNA accumulation |
| Q21195672 | Biology of recently discovered cytokines: interleukin-17--a unique inflammatory cytokine with roles in bone biology and arthritis |
| Q36791858 | Biphasic regulation of Il2 transcription in CD4+ T cells: roles for TNF-alpha receptor signaling and chromatin structure |
| Q33933213 | Bispecific antibodies for treatment of cancer in experimental animal models and man. |
| Q56908649 | Blockade of CD28/B7 co-stimulation by mCTLA4-Hgamma1 inhibits antigen-induced lung eosinophilia but not Th2 cell development or recruitment in the lung |
| Q34396514 | Bone marrow-derived dendritic cell progenitors (NLDC 145+, MHC class II+, B7-1dim, B7-2-) induce alloantigen-specific hyporesponsiveness in murine T lymphocytes |
| Q38837466 | CD28 Costimulation: From Mechanism to Therapy |
| Q24678846 | CD28 and CTLA-4 have opposing effects on the response of T cells to stimulation |
| Q42768793 | CD28 and T cell antigen receptor signal transduction coordinately regulate interleukin 2 gene expression in response to superantigen stimulation |
| Q51840948 | CD28 and inducible costimulator (ICOS) signalling can sustain CD154 expression on activated T cells |
| Q41767360 | CD28 blockade induces division-dependent downregulation of interleukin-2 receptor alpha |
| Q41642278 | CD28 interaction with B7 costimulates primary allogeneic proliferative responses and cytotoxicity mediated by small, resting T lymphocytes |
| Q39391600 | CD28 is required for optimal induction, but not maintenance, of vaccine-induced immunity to Blastomyces dermatitidis |
| Q40900024 | CD28 ligation induces transplantation tolerance by IFN-gamma-dependent depletion of T cells that recognize alloantigens |
| Q36297084 | CD28 promotes CD4+ T cell clonal expansion during infection independently of its YMNM and PYAP motifs. |
| Q72797913 | CD28 signal transduction: tyrosine phosphorylation and receptor association of phosphoinositide-3 kinase correlate with Ca(2+)-independent costimulatory activity |
| Q73589571 | CD28-B7 costimulation: a critical role for initiation and development of experimental autoimmune neuritis in C57BL/6 mice |
| Q41517114 | CD28-induced costimulation of T helper type 2 cells mediated by induction of responsiveness to interleukin 4. |
| Q40017821 | CD28-mediated costimulation in the absence of phosphatidylinositol 3-kinase association and activation |
| Q36362675 | CD28-mediated costimulation of interleukin 2 (IL-2) production plays a critical role in T cell priming for IL-4 and interferon gamma production |
| Q35828826 | CD28-mediated regulation of multiple myeloma cell proliferation and survival |
| Q45768838 | CD28/CTLA4-B7 interaction is dispensable for T cell stimulation by mouse mammary tumor virus superantigen but not for B cell differentiation and virus dissemination. |
| Q35621197 | CD4(+)CD25(+) regulatory T cells resist a novel form of CD28- and Fas-dependent p53-induced T cell apoptosis |
| Q34709777 | CD4+CD25+Foxp3+ regulatory T cells induce cytokine deprivation-mediated apoptosis of effector CD4+ T cells |
| Q30478206 | CD80 cytoplasmic domain controls localization of CD28, CTLA-4, and protein kinase Ctheta in the immunological synapse |
| Q36230356 | CTLA-4 is a second receptor for the B cell activation antigen B7 |
| Q24678229 | CTLA-4 ligation blocks CD28-dependent T cell activation |
| Q40936687 | Calcium-induced stabilization of AU-rich short-lived mRNAs is a common default response. |
| Q36729776 | Cell type-specific mechanisms of regulating expression of the ornithine decarboxylase gene after growth stimulation |
| Q34195614 | Cellular and molecular basis of human gamma delta T cell activation. Role of accessory molecules in alloactivation |
| Q34364003 | Cellular mutants define a common mRNA degradation pathway targeting cytokine AU-rich elements |
| Q74442070 | Ceramide-independent CD28 and TCR signaling but reduced IL-2 secretion in T cells of acid sphingomyelinase-deficient mice |
| Q33865924 | Changes in the stability of specific mRNA species in response to growth stage in Bacillus subtilis |
| Q35361010 | Characterisation of mucosal lymphoid aggregates in ulcerative colitis: immune cell phenotype and TcR-gammadelta expression |
| Q71825064 | Characterization of adenosine‐uridine‐rich RNA binding factors |
| Q30860052 | Characterization of the mRNA ligands bound by the RNA binding protein hnRNP A2 utilizing a novel in vivo technique |
| Q52053412 | Co-expression of B7-1 and ICAM-1 on tumors is required for rejection and the establishment of a memory response. |
| Q72611643 | Co-stimulation of T cells via CD28 inhibits human IgE production; reversal by pertussis toxin |
| Q72667369 | Co-stimulation with anti-CD28 (Kolt-2) enhances DNA synthesis by defective T cells in common variable immunodeficiency |
| Q36232150 | Coexpression and functional cooperation of CTLA-4 and CD28 on activated T lymphocytes |
| Q39837085 | Commentary: "The Role of T3 Surface Molecules in the Activation of Human Cells: A Two-Stimulus Requirement for IL-2 Production Reflects Events Occurring at a Pretranslational Level". |
| Q36363597 | Comparative analysis of B7-1 and B7-2 costimulatory ligands: expression and function |
| Q70911238 | Comparison of CD28-B7.1 and B7.2 functional interaction in resting human T cells: phosphatidylinositol 3-kinase association to CD28 and cytokine production |
| Q42448867 | Coordinate Transactivation of the Interleukin-2 CD28 Response Element by c-Rel and ATF-1/CREB2 |
| Q57240746 | Coordinate and Differential Regulation of GM-CSF and IL-3 Synthesis in Murine T Lymphocytes |
| Q40021091 | Costimulation by B7-1 and LFA-3 targets distinct nuclear factors that bind to the interleukin-2 promoter: B7-1 negatively regulates LFA-3-induced NF-AT DNA binding |
| Q35237202 | Costimulation of T lymphocytes: the role of CD28, CTLA-4, and B7/BB1 in interleukin-2 production and immunotherapy |
| Q71834546 | Costimulation regulates the kinetics of interleukin-2 response to bacterial superantigens |
| Q47969566 | Costimulatory CD80 (B7-1) and CD86 (B7-2) on cerebrospinal fluid cells in multiple sclerosis |
| Q37474920 | Costimulatory and coinhibitory receptors in anti-tumor immunity |
| Q35733851 | Costimulatory molecules and T-cell-B-cell interactions |
| Q28306324 | Crystal structure of a soluble CD28-Fab complex |
| Q39552152 | Cytokine Gene Expression in Normal Human Lymphocytes in Response to Stimulation |
| Q38346223 | Cytokine RNA expression in an equine CD4 + subset differentiated by expression of a novel 46-kDa surface protein |
| Q57240716 | Cytokines: Principles and prospects |
| Q34520749 | Cytotoxic T lymphocyte antigen-4 accumulation in the immunological synapse is regulated by TCR signal strength |
| Q24799770 | DNA array analysis of interleukin-2-regulated immediate/early genes |
| Q34497377 | Dcp1 links coactivators of mRNA decapping to Dcp2 by proline recognition |
| Q39739685 | Delineation of a novel pathway that regulates CD154 (CD40 ligand) expression |
| Q38298122 | Detection and characterization of a 3' untranslated region ribonucleoprotein complex associated with human alpha-globin mRNA stability |
| Q34189072 | Dexamethasone inhibits human interleukin 2 but not interleukin 2 receptor gene expression in vitro at the level of nuclear transcription |
| Q56905206 | Different mechanisms of cardiac allograft rejection in wildtype and CD28-deficient mice |
| Q36854921 | Differential Modulation by Delta9-Tetrahydrocannabinol (∆9-THC) of CD40 Ligand (CD40L) Expression in Activated Mouse Splenic CD4+ T cells |
| Q68237460 | Direct helper T cell-induced B cell differentiation involves interaction between T cell antigen CD28 and B cell activation antigen B7 |
| Q52574173 | Disruption of diacylglycerol metabolism impairs the induction of T cell anergy |
| Q36362732 | Disseminated human immunodeficiency virus 1 (HIV-1) infection in SCID-hu mice after peripheral inoculation with HIV-1 |
| Q58823344 | Dissociation between cytokine mRNA expression and protein production in shigellosis |
| Q41690578 | Dissociation between early and late events in T cell activation mediated through CD28 surface molecule |
| Q74045622 | Down-regulation of IL-4 gene transcription and control of Th2 cell differentiation by a mechanism involving NFAT1 |
| Q42825905 | ELAV protein HuA (HuR) can redistribute between nucleus and cytoplasm and is upregulated during serum stimulation and T cell activation |
| Q33833190 | Educating T cells: early events in the differentiation and commitment of cytokine-producing CD4+ and CD8+ T cells |
| Q36671402 | Effect of CD28 signal transduction on c-Rel in human peripheral blood T cells |
| Q54252645 | Effect of anti-CD3/anti-CD28/interleukin-2 stimulation of mononuclear cells on transforming growth factor beta inhibition of lymphokine-activated killer cell generation |
| Q28316111 | Effects of FK506 and cyclosporin A on cytokine production studied in vitro at a single-cell level |
| Q61863605 | Efficient expansion of tumor-infiltrating lymphocytes from solid tumors by stimulation with combined CD3 and CD28 monoclonal antibodies |
| Q67505990 | Evidence for a role of CD28RE as a response element for distinct mitogenic T cell activation signals |
| Q44518701 | Evidence for post-transcriptional regulation of interleukin-5 by dexamethasone |
| Q28477140 | Evidence implicating the Ras pathway in multiple CD28 costimulatory functions in CD4+ T cells |
| Q42500559 | Ex vivo induction of cytokine mRNA expression in human blood samples |
| Q40601662 | Exercise and the immune system. Natural killer cells, interleukins and related responses |
| Q37353657 | Exploiting apoptosis for therapeutic tolerance induction |
| Q39301452 | FDA-approved immunosuppressants targeting staphylococcal superantigens: mechanisms and insights |
| Q44729971 | FK-506 and cyclosporin A inhibit highly similar signal transduction pathways in human T lymphocytes |
| Q42100384 | Feedforward regulation of mRNA stability by prolonged extracellular signal-regulated kinase activity |
| Q40619563 | Functional Cooperation between Interleukin-17 and Tumor Necrosis Factor-α Is Mediated by CCAAT/Enhancer-binding Protein Family Members |
| Q40025338 | Functional analysis of a tripartite stability element within the CD40 ligand 3' untranslated region |
| Q56909168 | Functional characterization of a novel anti-B7 monoclonal antibody |
| Q73195896 | Functional disparity of distinct CD28 response elements toward mitogenic responses |
| Q41898118 | Functional expression of B7/BB1 on activated T lymphocytes |
| Q36231905 | Functional expression of the costimulatory molecule, B7/BB1, on murine dendritic cell populations |
| Q36544291 | Functional subsets of allergen-reactive human CD4+ T cells |
| Q40489810 | Genetically Engineered Tumor Vaccines |
| Q39696497 | Genome-wide analysis of mRNA decay in resting and activated primary human T lymphocytes |
| Q34154374 | Genomic expression programs and the integration of the CD28 costimulatory signal in T cell activation |
| Q35663586 | Global mRNA stabilization preferentially linked to translational repression during the endoplasmic reticulum stress response |
| Q28278858 | Grb2 Forms an Inducible Protein Complex with CD28 through a Src Homology 3 Domain-Proline Interaction |
| Q34574100 | Helper T cell IL-2 production is limited by negative feedback and STAT-dependent cytokine signals. |
| Q36363904 | Heterogeneity of single cell cytokine gene expression in clonal T cell populations |
| Q33781775 | Highly conserved RNA sequences that are sensors of environmental stress |
| Q35482842 | Homeostatic and innate immune responses: role of the transmembrane glycoprotein CD98 |
| Q33895914 | HuR binding to cytoplasmic mRNA is perturbed by heat shock |
| Q91686301 | HuR controls apoptosis and activation response without effects on cytokine 3' UTRs |
| Q43656132 | Human CD28 and CTLA-4 Ig superfamily genes are located on chromosome 2 at bands q33-q34. |
| Q95832132 | Human cancer germline antigen-specific cytotoxic T cell-what can we learn from patient |
| Q40788999 | IL-2 gene expression and NF-kappa B activation through CD28 requires reactive oxygen production by 5-lipoxygenase |
| Q40947449 | IL-2 gene therapy of solid tumors: an approach for the prevention of signal transduction defects in T cells |
| Q39651523 | IL-2 mRNA Stabilization upon PMA Stimulation Is Dependent on NF90-Ser647 Phosphorylation by Protein Kinase CβI |
| Q33886475 | Identification of HuR as a protein implicated in AUUUA-mediated mRNA decay |
| Q48194038 | Identification of a cDNA encoding the rat CD28 homologue |
| Q43697290 | Identification of mRNA that encodes an alternative form of H-CAM(CD44) in lymphoid and nonlymphoid tissues |
| Q74593470 | Immune Defense Mechanisms of the Dental Pulp |
| Q37802002 | Immunological aspect of cardiac remodeling: T lymphocyte subsets in inflammation-mediated cardiac fibrosis |
| Q33639360 | Immunomodulation by interference with co-stimulatory molecules: therapeutic perspectives in asthma |
| Q67688463 | Immunoregulatory cytokine release in rat spleen cell cultures after treatment with bleomycin and its analogues in vivo |
| Q37634944 | Immunosuppression for in vivo research: state-of-the-art protocols and experimental approaches |
| Q28370874 | Increased T cell cytotoxicity by Betathine-induced upregulation of TNFalpha |
| Q73323435 | Increased expression of B7-1 costimulatory molecule on cerebrospinal fluid cells of patients with multiple sclerosis and infectious central nervous system disease |
| Q38161200 | Induction and stability of the anergic phenotype in T cells |
| Q41395298 | Induction of a herpesvirus saimiri small RNA AU binding factor (AUBF70) activity and lymphokine mRNAs by T cell mitogens |
| Q36361179 | Induction of alloantigen-specific hyporesponsiveness in human T lymphocytes by blocking interaction of CD28 with its natural ligand B7/BB1 |
| Q42943549 | Induction of unresponsiveness and impaired T cell expansion by staphylococcal enterotoxin B in CD28-deficient mice |
| Q72410213 | Influence of CD28 co-stimulation on cytokine production is mainly regulated via interleukin-2 |
| Q40044464 | Influence of human T-cell leukemia virus type I tax and rex on interleukin-2 gene expression |
| Q73598666 | Initiation of hemodialysis treatment leads to improvement of T-cell activation in patients with end-stage renal disease |
| Q38356811 | Interaction between the mRNA of the 55-kDa tumor necrosis factor receptor and cellular proteins. Possible involvement in post-transcriptional regulation of receptor expression |
| Q52527463 | Interaction of AU-rich sequence binding proteins with actin: Possible involvement of the actin cytoskeleton in lymphokine mRNA turnover |
| Q44434230 | Interleukin (IL)-4 production by human T cells: differential regulation of IL-4 vs. IL-2 production |
| Q24679768 | Interleukin 12 synergizes with B7/CD28 interaction in inducing efficient proliferation and cytokine production of human T cells |
| Q36774362 | Interleukin-1 synergy with phosphoinositide pathway agonists for induction of interleukin-2 gene expression: molecular basis of costimulation |
| Q40019163 | Interleukin-11 mRNA stabilization in phorbol ester-stimulated primate bone marrow stromal cells |
| Q77355821 | Interleukin-18: A Novel Cytokine That Augments Both Innate and Acquired Immunity |
| Q41722182 | Interleukin-2, Interleukin-15, and Their Receptors |
| Q41302058 | Interleukin-3 mRNA Stabilization by a trans-Acting Mechanism in Autocrine Tumors Lacking Interleukin-3 Gene Rearrangements |
| Q74503183 | Interleukin-5 mRNA Stability in Human T Cells Is Regulated Differently than Interleukin-2, Interleukin-3, Interleukin-4, Granulocyte/Macrophage Colony-stimulating Factor, and Interferon- γ |
| Q72664500 | Interleukin-7 is a potent co-stimulus of the adhesion pathway involving CD2 and CD28 molecules |
| Q36667235 | Intrarenal antigens activate CD4+ cells via co-stimulatory signals from dendritic cells |
| Q36400671 | Involvement of Bruton's tyrosine kinase in FcepsilonRI-dependent mast cell degranulation and cytokine production |
| Q36380370 | Itk Negatively Regulates Induction of T Cell Proliferation by CD28 Costimulation |
| Q77300087 | IκB Kinases Serve as a Target of CD28 Signaling |
| Q54105156 | JNK2 is required for efficient T-cell activation and apoptosis but not for normal lymphocyte development. |
| Q36776184 | KSRP: a checkpoint for inflammatory cytokine production in astrocytes |
| Q46691006 | Lidocaine down-regulates nuclear factor-kappaB signalling and inhibits cytokine production and T cell proliferation |
| Q41513250 | Ligation of B7 with CD28/CTLA-4 on T cells results in CD40 ligand expression, interleukin-4 secretion and efficient help for antibody production by B cells |
| Q41522256 | Ligation of CD28 receptor by B7 induces formation of D-3 phosphoinositides in T lymphocytes independently of T cell receptor/CD3 activation |
| Q36350453 | Lymphokine gene expression in vivo is inhibited by cyclosporin A. |
| Q34061664 | Mammalian ribonucleotide reductase R1 mRNA stability under normal and phorbol ester stimulating conditions: involvement of a cis-trans interaction at the 3' untranslated region |
| Q52052670 | Mechanism of enhanced antigen presentation by B cells activated with anti-mu plus interferon-gamma: role of B7-2 in the activation of naive and memory CD4+ T cells |
| Q37424488 | Messenger RNA half-life measurements in mammalian cells |
| Q36362877 | Mice transgenic for a soluble form of murine CTLA-4 show enhanced expansion of antigen-specific CD4+ T cells and defective antibody production in vivo |
| Q77206870 | Mice with a fluorescent marker for interleukin 2 gene activation |
| Q42795863 | Mitogen-responsive expression of RhoB is regulated by RNA stability |
| Q36366967 | Models of T cell anergy: is there a common molecular mechanism? |
| Q36494214 | Modification of accessory molecule signaling |
| Q37172115 | Modulation of T lymphocyte replicative senescence via TNF-{alpha} inhibition: role of caspase-3. |
| Q24535662 | Modulation of TCR-induced transcriptional profiles by ligation of CD28, ICOS, and CTLA-4 receptors |
| Q36578210 | Molecular Events Mediating T Cell Activation |
| Q40773069 | Molecular Mechanisms of IL-2 Gene Regulation Following Costimulation Through LFA-1 |
| Q44967860 | Molecular characterization of Cynoglossus semilaevis CD28 |
| Q48673042 | Molecular mechanism of regulation of pentylenetetrazol-induced calcium entry by 3′-untranslated region of a seizure-related cDNA, PTZ-17, in Xenopus oocytes |
| Q36466372 | Molecular regulation of T-cell anergy |
| Q36487389 | Molecular regulation of human interleukin 2 and T-cell function by interleukin 4 |
| Q24793730 | Multiple functions for CD28 and cytotoxic T lymphocyte antigen-4 during different phases of T cell responses: implications for arthritis and autoimmune diseases |
| Q80673128 | Mutant Cu/Zn-superoxide dismutase associated with amyotrophic lateral sclerosis destabilizes vascular endothelial growth factor mRNA and downregulates its expression |
| Q34720640 | NF-kappaB family of transcription factors: central regulators of innate and adaptive immune functions. |
| Q37474904 | Negative regulators of T-cell activation: potential targets for therapeutic intervention in cancer, autoimmune disease, and persistent infections |
| Q40492275 | New strategies for enhancing the immunogenicity of tumors |
| Q45855741 | Non-mitogenic T cell activation signals are sufficient for induction of human immunodeficiency virus transcription |
| Q47927425 | Non‐responsiveness of antigen‐experienced CD4 T cells reflects more stringent co‐stimulatory requirements |
| Q71070150 | Nuclear appearance of a factor that binds the CD28 response element within the interleukin-2 enhancer correlates with interleukin-2 production |
| Q46712969 | Nuclear export of NF90 is required for interleukin-2 mRNA stabilization |
| Q35193952 | Nucleolin and YB-1 are required for JNK-mediated interleukin-2 mRNA stabilization during T-cell activation |
| Q29620269 | Overexpression of HuR, a nuclear-cytoplasmic shuttling protein, increases the invivo stability of ARE-containing mRNAs |
| Q42412035 | PAB1 self-association precludes its binding to poly(A), thereby accelerating CCR4 deadenylation in vivo |
| Q39460786 | Parallel and independent regulation of interleukin-3 mRNA turnover by phosphatidylinositol 3-kinase and p38 mitogen-activated protein kinase |
| Q47926335 | Pattern of cytokine expression in circulation CD57+ T cells from long-term renal allograft recipients |
| Q45144291 | Patterns of coordinate down-regulation of ARE-containing transcripts following immune cell activation. |
| Q36357068 | Perforin and serine esterase gene expression in stimulated human T cells. Kinetics, mitogen requirements, and effects of cyclosporin A |
| Q36229760 | Peripheral tolerance to alloantigen results from altered regulation of the interleukin 2 pathway |
| Q41371599 | Phosphatidylinositol 3-kinase activity is not essential for CD28 costimulatory activity in Jurkat T cells: studies with a selective inhibitor, wortmannin |
| Q33274643 | Pin1 modulates the type 1 immune response |
| Q47605047 | Polysome-profiling in small tissue samples |
| Q41051636 | Post-Transcriptional Regulation of UV Induced TNF-α Expression |
| Q71977447 | Post-transcriptional Regulation of Human Interleukin-2 Gene Expression at Processing of Precursor Transcripts |
| Q37113415 | Post-transcriptional control of cytokine production |
| Q40531602 | Post-transcriptional regulation of gro alpha, beta, gamma, and IL-8 mRNAs by IL-1 beta |
| Q37661362 | Post-transcriptional regulons coordinate the initiation and resolution of inflammation |
| Q36754850 | Postinduction turnoff of beta-interferon gene expression |
| Q41722118 | Posttranscriptional Regulation of mRNAs Important in T Cell Function |
| Q36472030 | Posttranscriptional mechanisms regulating the inflammatory response. |
| Q37153447 | Posttranscriptional regulation of IL-13 in T cells: role of the RNA-binding protein HuR. |
| Q37397424 | Posttranscriptional regulation of urokinase plasminogen activator receptor messenger RNA levels by leukocyte integrin engagement |
| Q56909292 | Preferential dependence of autoantibody production in murine lupus on CD86 costimulatory molecule |
| Q33927983 | Primary combined immunodeficiency resulting from defective transcription of multiple T-cell lymphokine genes. |
| Q34225129 | Production of granulocyte/macrophage-colony-stimulating factor by human natural killer cells. Modulation by the p75 subunit of the interleukin 2 receptor and by the CD2 receptor |
| Q52081944 | Production of tumor necrosis factor-α by naive or memory T lymphocytes activated via CD28 |
| Q36366867 | Protection against lethal toxic shock by targeted disruption of the CD28 gene |
| Q36353444 | Protein kinase regulates tumor necrosis factor mRNA stability in virus-stimulated astrocytes |
| Q24681529 | Protein ligands to HuR modulate its interaction with target mRNAs in vivo |
| Q24629236 | Purification, characterization, and cDNA cloning of an AU-rich element RNA-binding protein, AUF1 |
| Q30252424 | RNA stability regulates human T cell leukemia virus type 1 gene expression in chronically-infected CD4 T cells |
| Q29615186 | RNA stabilization by the AU-rich element binding protein, HuR, an ELAV protein |
| Q34042788 | RNA-binding protein HuR is required for stabilization of SLC11A1 mRNA and SLC11A1 protein expression |
| Q39069088 | RSK-mediated nuclear accumulation of the cold-shock Y-box protein-1 controls proliferation of T cells and T-ALL blasts |
| Q40016682 | Rapid mRNA degradation mediated by the c-fos 3' AU-rich element and that mediated by the granulocyte-macrophage colony-stimulating factor 3' AU-rich element occur through similar polysome-associated mechanisms |
| Q36776927 | Rapid transit in the immune cells: the role of mRNA turnover regulation. |
| Q24548269 | RasGAP-associated endoribonuclease G3Bp: selective RNA degradation and phosphorylation-dependent localization |
| Q38068698 | Recent progress in conventional and biologic therapy for systemic lupus erythematosus |
| Q72656302 | Reduced interleukin-2 (IL-2) production in common variable immunodeficiency is due to a primary abnormality of CD4+ T cell differentiation |
| Q72589389 | Regulation of 4-1BB expression by cell-cell interactions and the cytokines, interleukin-2 and interleukin-4 |
| Q33805318 | Regulation of HLA class II gene expression: the case for posttranscriptional control levels |
| Q38336999 | Regulation of Interleukin-2 Gene Enhancer Activity by the T Cell Accessory Molecule CD28 |
| Q40847476 | Regulation of Nramp1 mRNA stability by oxidants and protein kinase C in RAW264.7 macrophages expressing Nramp1(Gly169). |
| Q68327297 | Regulation of T-cell differentiation by CD2 and CD28 accessory molecules |
| Q42250579 | Regulation of T-cell lymphokine gene transcription by the accessory molecule CD28 |
| Q41353524 | Regulation of interferon-gamma mRNA in a cytolytic T cell clone: Ca(2+)-induced transcription followed by mRNA stabilization through activation of protein kinase C or increase in cAMP. |
| Q36551451 | Regulation of interleukin 2 gene expression by CD28 costimulation in mouse T-cell clones: both nuclear and cytoplasmic RNAs are regulated with complex kinetics |
| Q55037215 | Regulation of interleukin-4 production in human mononuclear cells. |
| Q44631762 | Regulation of lymphokine expression in T cell activation. I. Rapid loss of interleukin-specific RNA after removal of the stimulating signal |
| Q37708161 | Regulation of mRNA abundance in activated T lymphocytes: identification of mRNA species affected by the inhibition of protein synthesis. |
| Q34464736 | Regulation of mRNA stability in the nervous system and beyond |
| Q34323793 | Regulation of nuclear gamma interferon gene expression by interleukin 12 (IL-12) and IL-2 represents a novel form of posttranscriptional control |
| Q34806626 | Regulation of pathways of mRNA destabilization and stabilization |
| Q42828948 | Regulation of pre-mRNA processing by src. |
| Q36258291 | Regulation of protease and protease inhibitor gene expression: the role of the 3'-UTR and lessons from the plasminogen activating system |
| Q33771053 | Regulation of the Stability of Heat-Stable Antigen mRNA by Interplay between Two Novel cis Elements in the 3′ Untranslated Region |
| Q34739326 | Regulation of the interleukin-2 CD28-responsive element by NF-ATp and various NF-kappaB/Rel transcription factors |
| Q34633260 | Regulatory T cells inhibit acute IFN-γ synthesis without blocking T-helper cell type 1 (Th1) differentiation via a compartmentalized requirement for IL-10 |
| Q36553588 | RelA is a potent transcriptional activator of the CD28 response element within the interleukin 2 promoter |
| Q40420721 | Removal of a 3' non-coding sequence is an initial step in degradation of gro alpha mRNA and is regulated by interleukin-1 |
| Q44219521 | Report from Vienna: in search of all surface molecules expressed on human leukocytes |
| Q73933707 | Requirement of a second signal via protein kinase C or protein kinase A for maximal expression of CD40 ligand. Involvement of transcriptional and posttranscriptional mechanisms |
| Q34287436 | Ribonucleoprotein infrastructure regulating the flow of genetic information between the genome and the proteome |
| Q35925037 | Role of CD28 in fatal autoimmune disorder in scurfy mice |
| Q34220264 | Role of CD4 molecule in the induction of interleukin 2 and interleukin 2 receptor in class II major histocompatibility complex-restricted antigen-specific T helper clones. T cell receptor/CD3 complex transmits CD4-dependent and CD4-independent signa |
| Q84599537 | Role of HLA and T lymphocytes in the immune response |
| Q36795816 | Role of TH-17 Cells in Rheumatic and Other Autoimmune Diseases |
| Q24676215 | Schnurri-3 (KRC) interacts with c-Jun to regulate the IL-2 gene in T cells |
| Q37871903 | Searching for "signal 2": costimulation requirements of γδ T cells. |
| Q24313100 | Selective CD28pYMNM mutations implicate phosphatidylinositol 3-kinase in CD86-CD28-mediated costimulation |
| Q42096048 | Selective degradation of early-response-gene mRNAs: functional analyses of sequence features of the AU-rich elements |
| Q52108416 | Selective loss of T cell functions in different stages of HIV infection. Early loss of anti-CD3-induced T cell proliferation followed by decreased anti-CD3-induced cytotoxic T lymphocyte generation in AIDS-related complex and AIDS. |
| Q71548652 | Severe combined immunodeficiency due to defective binding of the nuclear factor of activated T cells in T lymphocytes of two male siblings |
| Q37105156 | Signal transduction in T cells |
| Q41535275 | Signalling through CD28 T-cell activation pathway involves an inositol phospholipid-specific phospholipase C activity |
| Q71730910 | Signalling via CD28 of human naive neonatal T lymphocytes |
| Q30576507 | Signals and sequences that control CD28 localization to the central region of the immunological synapse |
| Q77408482 | Simulated microgravity inhibits the genetic expression of interleukin‐2 and its receptor in mitogen‐activated T lymphocytes |
| Q74058869 | Simultaneous detection of DNA synthesis and cytokine production in staphylococcal enterotoxin B activated CD4+ T lymphocytes by flow cytometry |
| Q71918623 | Sphingomyelin-ceramide turnover in CD28 costimulatory signaling |
| Q34322605 | Splicing factor SF2/ASF rescues IL-2 production in T cells from systemic lupus erythematosus patients by activating IL-2 transcription |
| Q37169604 | Spontaneous colitis occurrence in transgenic mice with altered B7-mediated costimulation |
| Q71808678 | Spontaneous production of various cytokines except IL-4 from CD4+ T cells in the affected organs of sarcoidosis patients |
| Q24296406 | Stabilization of Urokinase and Urokinase Receptor mRNAs by HuR Is Linked to Its Cytoplasmic Accumulation Induced by Activated Mitogen-Activated Protein Kinase-Activated Protein Kinase 2 |
| Q40017265 | Stabilization of vascular endothelial growth factor mRNA by hypoxia and hypoglycemia and coregulation with other ischemia-induced genes |
| Q37790856 | Staying Alive: T Cell Costimulation, CD28, and Bcl-xL |
| Q24680080 | Stimulation of CD28 triggers an association between CD28 and phosphatidylinositol 3-kinase in Jurkat T cells |
| Q74172337 | Strain difference in the induction of T-cell activation-associated, interferon gamma-dependent hepatic injury in mice |
| Q37051768 | Structure-function relationships in the IL-17 receptor: implications for signal transduction and therapy |
| Q36106477 | Substrate Rigidity Regulates Human T Cell Activation and Proliferation |
| Q41758057 | Superinduction of the human gene encoding low density lipoprotein receptor |
| Q34129776 | Susceptibility of interleukin-2-deficient mice to Toxoplasma gondii is associated with a defect in the production of gamma interferon |
| Q83352516 | Sustained B7/CD28 interactions and resultant phosphatidylinositol 3-kinase activity maintain G1-->S phase transitions at an optimal rate |
| Q37780978 | Sustained CD28 expression delays multiple features of replicative senescence in human CD8 T lymphocytes |
| Q44550029 | T Cell Activation Modulates Retrovirus-Mediated Gene Expression |
| Q36401427 | T Cell Receptor (TCR) Engagement Leads to Activation-induced Splicing of Tumor Necrosis Factor (TNF) Nuclear Pre-mRNA |
| Q71425889 | T cell activation by concanavalin A in the presence of cyclosporin A: immunosuppressor withdrawal induces NFATp translocation and interleukin-2 gene transcription |
| Q42807854 | T cell activation defect in hemodialysis patients: evidence for a role of the B7/CD28 pathway |
| Q35096703 | T cell anergy and costimulation |
| Q28300793 | T cell antigen CD28 binds to the GRB-2/SOS complex, regulators of p21ras |
| Q40492282 | T cell co-stimulation and in vivo tolerance |
| Q68242813 | T cell receptor/CD3 and CD28 use distinct intracellular signaling pathways |
| Q41472266 | T cells of staphylococcal enterotoxin B-tolerized autoimmune MRL-lpr/lpr mice require co-stimulation through the B7-CD28/CTLA-4 pathway for activation and can be reanergized in vivo by stimulation of the T cell receptor in the absence of this co-sti |
| Q34059260 | T lymphocyte costimulatory molecules in host defense and immunologic diseases |
| Q37929568 | T lymphocyte-derived colony-stimulating factors |
| Q34858190 | T-cell activation: a multidimensional signaling network. |
| Q33658811 | T-cell antigen CD28 mediates adhesion with B cells by interacting with activation antigen B7/BB-1. |
| Q38168010 | T-cell costimulatory blockade in organ transplantation |
| Q34572202 | T-cell regulation by CD28 and CTLA-4. |
| Q42097974 | TCR and CD28 activate the transcription factor NF-κB in T-cells via distinct adaptor signaling complexes |
| Q73307207 | TCR-independent CD28-mediated gene expression in peripheral blood lymphocytes from donors chronically infected with HIV-1 |
| Q37233454 | Targeted knock-in mice expressing mutations of CD28 reveal an essential pathway for costimulation |
| Q35037678 | Targeting tumours with genetically enhanced T lymphocytes |
| Q73617857 | Temporal and subunit-specific modulations of the Rel/NF-kappaB transcription factors through CD28 costimulation |
| Q73937153 | Temporal relationship between immune cell influx and the expression of inducible nitric oxide synthase, interleukin-4 and interferon-gamma in pancreatic islets of NOD mice following adoptive transfer of diabetic spleen cells |
| Q42941758 | Thalidomide exerts its inhibitory action on tumor necrosis factor alpha by enhancing mRNA degradation |
| Q24558903 | The ARE-dependent mRNA-destabilizing activity of BRF1 is regulated by protein kinase B |
| Q41532481 | The B7 adhesion molecule is expressed on activated human T cells: functional involvement in T-T cell interactions |
| Q77137017 | The Development of a Th1-Type Response and Resistance toLeishmania majorInfection in the Absence of CD40-CD40L Costimulation |
| Q24567618 | The Herpesvirus saimiri small nuclear RNAs recruit AU-rich element-binding proteins but do not alter host AU-rich element-containing mRNA levels in virally transformed T cells |
| Q38321239 | The NFAT-1 DNA binding complex in activated T cells contains Fra-1 and JunB. |
| Q37161112 | The RRM1 domain of the poly(A)-binding protein from Saccharomyces cerevisiae is critical to control of mRNA deadenylation. |
| Q36362769 | The combination of anti-B7 monoclonal antibody and cyclosporin A induces alloantigen-specific anergy during a primary mixed lymphocyte reaction. |
| Q35348304 | The development of functionally responsive T cells |
| Q45760557 | The effects of CD3, CD4 and CD28 signaling on lymphocytes during human immunodeficiency virus‐1 infection |
| Q52942338 | The interaction properties of costimulatory molecules revisited |
| Q93163538 | The interdependence of mammary-specific super-enhancers and their native promoters facilitates gene activation during pregnancy |
| Q78115850 | The mechanism of activation of NK-cell IFN-gamma production by ligation of CD28 |
| Q44095614 | The murine gene for cellular retinoic acid-binding protein type II. Genomic organization, chromosomal localization, and post-transcriptional regulation by retinoic acid |
| Q36550587 | The nonamer UUAUUUAUU is the key AU-rich sequence motif that mediates mRNA degradation |
| Q36423252 | The p38 mitogen-activated protein kinase signaling cascade in CD4 T cells |
| Q67898890 | The role of interleukin-6 in mitogenic T-cell activation: Detection of interleukin-2 heteronuclear RNA by polymerase chain reaction |
| Q33709343 | The role of the T cell in autoimmune inflammation |
| Q41647843 | The role of the bystander effect in suicide gene therapy |
| Q36363984 | The tissue distribution of the B7-2 costimulator in mice: abundant expression on dendritic cells in situ and during maturation in vitro |
| Q41736991 | The use of anti-CD3 and anti-CD28 monoclonal antibodies to clone and expand human antigen-specific T cells |
| Q33799265 | Tolerance after liver transplantation: does it exist and can immunosuppression be withdrawn? |
| Q33813616 | Toxic shock syndrome toxin-1-mediated toxicity inhibited by neutralizing antibodies late in the course of continual in vivo and in vitro exposure |
| Q35782412 | Transcriptional and post-transcriptional regulation of interleukin-8. |
| Q41517433 | Transcriptional regulation of interleukin-2 gene expression by CD69-generated signals. |
| Q37474964 | Translating costimulation blockade to the clinic: lessons learned from three pathways |
| Q38212816 | Translational control of immune responses: from transcripts to translatomes |
| Q89486105 | Translational repression of pre-formed cytokine-encoding mRNA prevents chronic activation of memory T cells |
| Q56907458 | Transmission disequilibrium of maternally-inherited CTLA-4 microsatellite alleles in idiopathic recurrent miscarriage |
| Q37160867 | Tristetraprolin mediates interferon-gamma mRNA decay |
| Q42495005 | Trypanosoma cruzi infection suppresses nuclear factors that bind to specific sites on the interleukin-2 enhancer |
| Q40433289 | Tumor Therapy by Immune Recruitment with Bispecific Antibodies |
| Q42451007 | Tumor necrosis factor alpha-induced glucose transporter (GLUT-1) mRNA stabilization in 3T3-L1 preadipocytes. Regulation by the adenosine-uridine binding factor |
| Q71245948 | Turnover and translation of in vitro synthesized messenger RNAs in transfected, normal cells |
| Q37392111 | Two pathways of costimulation through CD28. |
| Q33606814 | Type I (insulin-dependent) diabetes is a Th1- and Th2-mediated autoimmune disease |
| Q74339602 | Upregulated intragraft gene expression, ICAM-1 and IL-2R molecules, and apoptotic epithelial cells during rejection of rat small intestine allografts |
| Q53650488 | Variation in the CTLA4 3'UTR has phenotypic consequences for autoreactive T cells and associates with genetic risk for type 1 diabetes. |
| Q33954794 | Versatile role for hnRNP D isoforms in the differential regulation of cytoplasmic mRNA turnover |
| Q34357964 | Xenobiotics, chimerism and the induction of tolerance following organ transplantation |
| Q36376229 | c-Jun NH2-terminal kinase (JNK)1 and JNK2 have similar and stage-dependent roles in regulating T cell apoptosis and proliferation |
| Q33916521 | cAMP inhibits induction of interleukin 2 but not of interleukin 4 in T cells |
| Q34670591 | hnRNP C increases amyloid precursor protein (APP) production by stabilizing APP mRNA |
| Q36555520 | mRNA decay mediated by two distinct AU-rich elements from c-fos and granulocyte-macrophage colony-stimulating factor transcripts: different deadenylation kinetics and uncoupling from translation |
| Q35011995 | mRNA degradation machines in eukaryotic cells |
| Q29616374 | mRNA stability in mammalian cells |
| Q41860866 | miR-29 Acts as a Decoy in Sarcomas to Protect the Tumor Suppressor A20 mRNA from Degradation by HuR |
| Q40979144 | p21WAF1 expression by an activator of protein kinase C is regulated mainly at the post-transcriptional level in cells lacking p53: important role of RNA stabilization |
| Q24311999 | p56Lck and p59Fyn regulate CD28 binding to phosphatidylinositol 3-kinase, growth factor receptor-bound protein GRB-2, and T cell-specific protein-tyrosine kinase ITK: implications for T-cell costimulation |
| Q34721076 | γδ T Cells Acquire Effector Fates in the Thymus and Differentiate into Cytokine-Producing Effectors in a Listeria Model of Infection Independently of CD28 Costimulation |
Search more.