Effect of niacin/nicotinamide deficiency on the diabetogenic effect of streptozotocin

scientific article published on 01 January 1988

Effect of niacin/nicotinamide deficiency on the diabetogenic effect of streptozotocin is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1007/BF01960237
P698PubMed publication ID2965027

P2093author name stringJ R Wright
P E Lacy
J Mendola
P2860cites workDrugs producing diabetes through damage of the insulin secreting cellsQ28247851
Streptozotocin diabetes. Correlation with extent of depression of pancreatic islet nicotinamide adenine dinucleotideQ28363187
Influence of nicotinamide and pyridine nucleotides on streptozotocin and alloxan-induced pancreatic B cell cytotoxicityQ44126879
Streptozotocin diabetes: time course of irreversible B-cell damage; further observations on prevention by nicotinamideQ44217133
The use of nicotinamide to modify the toxicity of streptozotocin diabetes without loss of antitumor activity.Q53709539
Significance of streptozotocin induced nicotinamide-adenine-dinucleotide (NAD) degradation in mouse pancreatic islets.Q53720022
Streptozotocin and alloxan induce DNA strand breaks and poly(ADP–ribose) synthetase in pancreatic isletsQ59060353
Mechanisms of nitrosourea-induced beta-cell damage. Alterations in DNA.Q64911421
Reversal of streptozotocin diabetes with nicotinamideQ68590302
Pyridine nucleotide depletion in pancreatic islets associated with streptozotocin-induced diabetesQ68644058
Streptozotocin diabetes--further studies on the mechanism of depression of nicotinamide adenine dinucleotide concentrations in mouse pancreatic islets and liverQ68673917
The role of poly(ADP-ribose) synthetase in the development of insulin-dependent diabetes and islet B-cell regenerationQ70084809
Effects of streptozotocin on a clonal isolate of rat insulinoma cellsQ72388617
Protection by superoxide dismutase, catalase, and poly(ADP-ribose) synthetase inhibitors against alloxan- and streptozotocin-induced islet DNA strand breaks and against the inhibition of proinsulin synthesisQ72929886
P433issue1
P304page(s)38-40
P577publication date1988-01-01
P1433published inExperientiaQ21385347
P1476titleEffect of niacin/nicotinamide deficiency on the diabetogenic effect of streptozotocin
P478volume44

Reverse relations

cites work (P2860)
Q28512196Absence of a reductase, NCB5OR, causes insulin-deficient diabetes
Q40632082Nicotinamide treatment in the prevention of insulin-dependent diabetes mellitus.
Q33727613Resveratrol, an activator of SIRT1, upregulates sarcoplasmic calcium ATPase and improves cardiac function in diabetic cardiomyopathy
Q44906464Tilapia islet grafts are highly alloxan-resistant

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