Structure of mutant alleles at the aprt locus of Chinese hamster ovary cells

scientific article published on 01 July 1983

Structure of mutant alleles at the aprt locus of Chinese hamster ovary cells is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1016/S0022-2836(83)80099-0
P698PubMed publication ID6308265

P2093author name stringJ Nalbantoglu
M Meuth
O Goncalves
P2860cites workDetection of specific sequences among DNA fragments separated by gel electrophoresisQ25939003
Labeling deoxyribonucleic acid to high specific activity in vitro by nick translation with DNA polymerase IQ27860885
Regulation of white locus expression: The structure of mutant alleles at the white locus of Drosophila melanogasterQ28264891
SINEs and LINEs: Highly repeated short and long interspersed sequences in mammalian genomesQ34055215
Chromosome segregation is frequently associated with the expression of recessive mutations in mouse cellsQ35330957
Isolation of a genomic clone partially encoding human hypoxanthine phosphoribosyltransferaseQ36308497
Hypoxanthine-guanine phosphoribosyltransferase genes of mouse and Chinese hamster: construction and sequence analysis of cDNA recombinantsQ36596960
Isolation of transforming DNA: cloning the hamster aprt geneQ36668696
Model involving gene inactivation in the generation of autosomal recessive mutants in mammalian cells in cultureQ36975126
Alterations of gene structure in ethyl methane sulfonate-induced mutants of mammalian cellsQ36976383
The HPRT locusQ39787761
Induction of gene conversion in diploid yeast by chemicals: Correlation with mutagenic action and its relevance in genotoxicity screeningQ39794363
Short interspersed repetitive DNA elements in eucaryotes: Transposable DNA elements generated by reverse transcription of RNA pol III transcripts?Q40128345
On the nature of hereditable variation in cultured somatic cellsQ40555367
Phenotypic expression in E. coli of a DNA sequence coding for mouse dihydrofolate reductaseQ40947691
Genetic studies of the lac repressor. VII. On the molecular nature of spontaneous hotspots in the lacI gene of Escherichia coliQ41008292
Genetic studies of the lac repressor. IV. Mutagenic specificity in the lacI gene of Escherichia coliQ41379292
Mutants of cultured chinese hamster cells deficient in adenine phosphoribosyl transferaseQ44240634
Forward and reverse mutations affecting the kinetics and apparent molecular weight of mammalian HGPRTQ47326228
Direct repeats flank three small nuclear RNA pseudogenes in the human genomeQ48408161
Structure of the Drosophila mutable allele, white-crimson, and its white-ivory and wild-type derivatives.Q52518677
High-frequency nonrandom mutational event at the adenine phosphoribosyltransferase (aprt) locus of sib-selected CHO variants heterozygous for aprt.Q54523540
Mutations affecting adenine phosphoribosyl transferase activity in Chinese hamster cells.Q54638670
On the formation of spontaneous deletions: The importance of short sequence homologies in the generation of large deletionsQ56521354
Marker segregation without chromosome loss at the emt locus in Chinese hamster cell hybridsQ71981196
Genetic events associated with an insertion mutation in yeastQ72861673
P433issue3
P304page(s)575-594
P577publication date1983-07-01
P1433published inJournal of Molecular BiologyQ925779
P1476titleStructure of mutant alleles at the aprt locus of Chinese hamster ovary cells
P478volume167

Reverse relations

cites work (P2860)
Q340426348-Methoxypsoralen induced mutations are highly targeted at crosslinkable sites of photoaddition on the non-transcribed strand of a mammalian chromosomal gene
Q40971355A comparison of mutational specificity of mutations induced by S9-activated B[a]P and benzo[a]pyrene-7,8-diol-9,10-epoxide at the endogenous aprt gene in CHO cells
Q28298034Analysis of germline and in vivo somatic mutations in the human adenine phosphoribosyltransferase gene: Mutational hot spots at the intron 4 splice donor site and at codon 87
Q36896711Characterization of a family of gamma-ray-induced CHO mutants demonstrates that the ldlA locus is diploid and encodes the low-density lipoprotein receptor
Q37397535Characterization of mutations induced by 2-(N-acetoxy-N-acetyl)aminofluorene in the dihydrofolate reductase gene of cultured hamster cells
Q36586672Cloning of a functional human adenine phosphoribosyltransferase (APRT) gene: Identification of a restriction fragment length polymorphism and preliminary analysis of DNAs from APRT-deficient families and cell mutants
Q36594693Cloning the complete human adenine phosphoribosyl transferase gene
Q33880958Complementation of sensitivity to alkylating agents in Escherichia coli and Chinese hamster ovary cells by expression of a cloned bacterial DNA repair gene
Q35055645DNA amplification--deletion in a spontaneous mutation of the hamster aprt locus: structure and sequence of the novel joint
Q40658984DNA sequence analysis of spontaneous mutations at the aprt locus of hamster cells
Q28378652Direct selection for mutations affecting specific splice sites in a hamster dihydrofolate reductase minigene
Q42573053Gene silencing by DNA methylation and dual inheritance in Chinese hamster ovary cells.
Q33847226High frequency of large spontaneous deletions of DNA in tumor-derived CHEF cells
Q36894651Induction of adenine salvage in mouse cell lines deficient in adenine phosphoribosyltransferase
Q39633008Ionizing radiation-induced mutagenesis
Q36222559Isolation and characterization of Chinese hamster ovary cell mutants defective in intracellular low density lipoprotein-cholesterol trafficking
Q36835999Molecular characterization of 15 rearrangements among 90 human in vivo somatic mutants shows that deletions predominate
Q33885393Mouse transgenes in human cells detect specific base substitutions.
Q41680723Multiple dispersed spontaneous mutations: a novel pathway of mutation in a malignant human cell line
Q41362645Mutational specificity of animal cell DNA polymerases
Q67804434Mutational specificity of the dnaE173 mutator associated with a defect in the catalytic subunit of DNA polymerase III of Escherichia coli
Q34634648Next-nucleotide effects in mutations driven by DNA precursor pool imbalances at the aprt locus of Chinese hamster ovary cells
Q41667952Reduction to homozygosity is the predominant spontaneous mutational event in cultured human lymphoblastoid cells
Q24647405Repair of site-specific double-strand breaks in a mammalian chromosome by homologous and illegitimate recombination
Q33952085Southern analysis of genomic alterations in gamma-ray-induced aprt- hamster cell mutants
Q33574499Spectrum of spontaneous mutation at the APRT locus of Chinese hamster ovary cells: an analysis at the DNA sequence level
Q33879867Spontaneous deletion formation at the aprt locus of hamster cells: the presence of short sequence homologies and dyad symmetries at deletion termini
Q36947478Structural Alterations of the aprt Locus Induced by Deoxyribonucleoside Triphosphate Pool Imbalances in Chinese Hamster Ovary Cells
Q37935123The mutational spectrum of single base-pair substitutions causing human genetic disease: patterns and predictions
Q40557945The rat albumin gene promoter is appropriately regulated in transient but not in stable transfections