Deficient activity of FAD-linked glycerophosphate dehydrogenase in islets of GK rats

scientific article published on 01 August 1993

Deficient activity of FAD-linked glycerophosphate dehydrogenase in islets of GK rats is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1007/BF00401142
P698PubMed publication ID8405739

P50authorSuad EfendicQ5627647
Claes-Göran ÖstensonQ76345706
P2093author name stringW J Malaisse
A Sener
F Malaisse-Lagae
S Meuris
J Rasschaert
S M Abdel-Halim
P2860cites workProtein measurement with the Folin phenol reagentQ20900776
Glucose-sensing by the pancreatic B-cell: the mitochondrial partQ36142137
Structural and functional considerations of GABA in islets of Langerhans. Beta-cells and nervesQ37444051
Hexose metabolism in pancreatic islets. Inhibition of hexokinaseQ41871850
Hexose metabolism in pancreatic islets. Glucose-induced and Ca(2+)-dependent activation of FAD-glycerophosphate dehydrogenaseQ42034875
Impairment of Glycerol Phosphate Shuttle in Islets From Rats With Diabetes Induced by Neonatal StreptozocinQ42470282
Beta-cell insensitivity to glucose in the GK rat, a spontaneous nonobese model for type II diabetesQ42475849
Hexose metabolism in pancreatic islets. Participation of Ca2(+)-sensitive 2-ketoglutarate dehydrogenase in the regulation of mitochondrial function.Q52106528
Enzymic and metabolic anomalies in islets of diabetic rats: relationship to B cell massQ67487939
Radioisotopic assay of aspartate and alanine aminotransferaseQ67518393
Study of hexose transport, glycerol phosphate shuttle and Krebs cycle in islets of adult rats injected with streptozotocin during the neonatal periodQ68053773
Long term in vitro effects of streptozotocin, interleukin-1, and high glucose concentration on the activity of mitochondrial dehydrogenases and the secretion of insulin in pancreatic isletsQ68056514
A sensitive radioisotopic method for the measurement of NAD(P)H: its application to the assay of metabolites and enzymatic activitiesQ68838591
Abnormal insulin secretion and glucose metabolism in pancreatic islets from the spontaneously diabetic GK ratQ70567565
Metabolic response to nonglucidic nutrient secretagogues and enzymatic activities in pancreatic islets of adult rats after neonatal streptozotocin administrationQ70688751
Effect of streptozotocin and nicotinamide upon FAD-glycerophosphate dehydrogenase activity and insulin release in purified pancreatic B-cellsQ70699811
Coated Charcoal Immunoassay of InsulinQ71162157
Criteria of reliability for light microscopic immunocytochemical stainingQ71400220
An improved fluorometric assay for DNAQ71759750
A modified peroxidase--antiperoxidase procedure for improved localization of tissue antigens: localization of substance P in rat spinal cordQ72608115
P433issue8
P304page(s)722-726
P577publication date1993-08-01
P1433published inDiabetologiaQ5270140
P1476titleDeficient activity of FAD-linked glycerophosphate dehydrogenase in islets of GK rats
P478volume36

Reverse relations

cites work (P2860)
Q51575536Altered endothelial/pericyte ratio in Goto-Kakizaki rat retina.
Q40837240Aspects of novel sites of regulation of the insulin stimulus-secretion coupling in normal and diabetic pancreatic islets
Q35883220Beta-cell lipotoxicity in the pathogenesis of non-insulin-dependent diabetes mellitus of obese rats: impairment in adipocyte-beta-cell relationships
Q43652401Brain and liver mitochondria isolated from diabetic Goto-Kakizaki rats show different susceptibility to induced oxidative stress.
Q58329850Decreased cortical bone thickness in spontaneously non-insulin-dependent diabetic GK rats
Q33989543Decreased levels of metabolic enzymes in pancreatic islets of patients with type 2 diabetes
Q34997990Differences between human and rodent pancreatic islets: low pyruvate carboxylase, atp citrate lyase, and pyruvate carboxylation and high glucose-stimulated acetoacetate in human pancreatic islets
Q42448821Effect of dehydroepiandrosterone in hereditarily diabetic rats
Q28626444Enzymatic, metabolic and secretory patterns in human islets of type 2 (non-insulin-dependent) diabetic patients
Q73384096Evidence of enhancement of malate-aspartate shuttle activity in beta cells of streptozotocin-induced non-insulin-dependent diabetic rats
Q42852084Fatty acid pattern of pancreatic islet lipids in Goto-Kakizaki rats
Q42478438Hyperresponse in calcium-induced insulin release from electrically permeabilized pancreatic islets of diabetics GK rats and its defective augmentation by glucose
Q44493912Hypoglycaemia induces decreased islet blood perfusion mediated by the central nervous system in normal and Type 2 diabetic GK rats
Q34112236Identification and functional analysis of mutations in FAD-binding domain of mitochondrial glycerophosphate dehydrogenase in caucasian patients with type 2 diabetes mellitus.
Q72478625Impaired FAD-glycerophosphate dehydrogenase activity in islet and liver homogenates of fa/fa rats
Q30465190Impaired skeletal muscle glycogen synthase activation by insulin in the Goto-Kakizaki (G/K) rat.
Q38904596Inhibition of the malate-aspartate shuttle in mouse pancreatic islets abolishes glucagon secretion without affecting insulin secretion
Q40824621Is type 2 diabetes due to a deficiency of FAD-linked glycerophosphate dehydrogenase in pancreatic islets?
Q28577435Lower succinyl-CoA:3-ketoacid-CoA transferase (SCOT) and ATP citrate lyase in pancreatic islets of a rat model of type 2 diabetes: knockdown of SCOT inhibits insulin release in rat insulinoma cells
Q43590315Metabolic and functional studies on isolated islets in a new rat model of type 2 diabetes
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Q41911234Metabolism of endogenous nutrients in islets of Goto-Kakizaki (GK) rats
Q71993551Non‐insulin‐dependent Diabetes Mellitus and Islet B‐cell Mitochondrial Glycerophosphate Dehydrogenase Deficiency
Q41020120Overexpression of lactate dehydrogenase A attenuates glucose-induced insulin secretion in stable MIN-6 beta-cell lines
Q72572835Reduced sensitivity of dihydroxyacetone on ATP-sensitive K+ channels of pancreatic beta cells in GK rats
Q40946041Reduction of reactive oxygen species ameliorates metabolism-secretion coupling in islets of diabetic GK rats by suppressing lactate overproduction
Q48631222Respiratory chain activity and mitochondrial DNA content of nonpurified and purified pancreatic islet cells
Q79767738Rodent models for the study of type 2 diabetes in children (juvenile diabesity)
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