Modulation of drug cytotoxicity in wild-type and multidrug-resistant tumor cells by stereoisomeric series of C-20'-vinblastine congeners that lack antimicrotubule activity

scientific article published on 01 January 1993

Modulation of drug cytotoxicity in wild-type and multidrug-resistant tumor cells by stereoisomeric series of C-20'-vinblastine congeners that lack antimicrotubule activity is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1007/BF00686146
P698PubMed publication ID8431967

P2093author name stringW G Bornmann
M E Kuehne
L S Borman
P2860cites workEssential features of the P-glycoprotein pharmacophore as defined by a series of reserpine analogs that modulate multidrug resistanceQ34287731
Most drugs that reverse multidrug resistance also inhibit photoaffinity labeling of P-glycoprotein by a vinblastine analogQ34560047
Effects of calcium antagonists in multidrug resistant primary human renal cell carcinomasQ34648222
Microtubule Assembly in the Absence of Added NucleotidesQ35098486
Effect of cyclosporin A on daunorubicin accumulation in multidrug-resistant P388 leukemia cells measured by real-time flow cytometryQ35986320
Mechanism of multidrug resistanceQ39469004
Molecular biology of multidrug resistance in human cellsQ39514276
New aspects of clinical drug resistance: the role of gene amplification and the reversal of resistance in drug refractory cancerQ39700376
Biochemical studies on the in vitro assembly and disassembly of microtubulesQ39737818
Modulation of drug sensitivity by dipyridamole in multidrug resistant tumor cells in vitro.Q41175649
Verapamil and adriamycin in the treatment of drug-resistant ovarian cancer patientsQ41328786
Non-antitumor vinca alkaloids reverse multidrug resistance in P388 leukemia cells in vitroQ41379163
SDZ PSC 833, a non-immunosuppressive cyclosporine: its potency in overcoming P-glycoprotein-mediated multidrug resistance of murine leukemiaQ41639342
Two pyridine analogues with more effective ability to reverse multidrug resistance and with lower calcium channel blocking activity than their dihydropyridine counterpartsQ41734320
Cellular and biochemical characterization of thioxanthenes for reversal of multidrug resistance in human and murine cell linesQ41740569
Multidrug resistance in a human leukemic cell line selected for resistance to trimetrexate.Q41759737
Effects of indole alkaloids on multidrug resistance and labeling of P-glycoprotein by a photoaffinity analog of vinblastineQ41911849
Physical-chemical properties shared by compounds that modulate multidrug resistance in human leukemic cells.Q41912189
Reversal by cefoperazone of resistance to etoposide, doxorubicin, and vinblastine in multidrug resistant human sarcoma cellsQ46679193
Enhancement of anthracycline growth inhibition in parent and multidrug-resistant Chinese hamster ovary cells by cyclosporin A and its analogues.Q54340770
Increased accumulation of vincristine and adriamycin in drug-resistant P388 tumor cells following incubation with calcium antagonists and calmodulin inhibitors.Q54510017
Restored in vitro sensitivity of adriamycin- and vincristine-resistant P388 leukemia with reserpineQ54532319
Reversal of resistance to vincristine in P388 leukemia by various polycyclic clinical drugs, with a special emphasis on quinacrineQ68285876
Single site-modified congeners of vinblastine dissociate its various anti-microtubule actionsQ68348224
Effect of bisbenzylisoquinoline (biscoclaurine) alkaloids on multidrug resistance in KB human cancer cellsQ68985262
Specific alterations in the biological activities of C-20'-modified vinblastine congenersQ69973823
Establishment of two parental cell lines and three clonal cell strains from rat colonic carcinomaQ70508033
Reversal of multidrug resistance by non-antitumor anthracycline analogsQ70972113
Circumvention of resistance to daunorubicin by N-acetyldaunorubicin in Ehrlich ascites tumorQ71140228
Comparison of anthracycline concentrations in S180 cell lines of varying sensitivityQ71235644
P433issue5
P921main subjectmultiple drug resistanceQ643839
P304page(s)343-349
P577publication date1993-01-01
P1433published inCancer Chemotherapy and PharmacologyQ326137
P1476titleModulation of drug cytotoxicity in wild-type and multidrug-resistant tumor cells by stereoisomeric series of C-20'-vinblastine congeners that lack antimicrotubule activity
P478volume31

Reverse relations

cites work (P2860)
Q43869053New method of synthesis of Vinca alkaloid derivatives
Q40535280Pharmacologic circumvention of multidrug resistance
Q40639456Syntheses and biological evaluation of vinblastine congeners
Q30310478The IBOGA alkaloids and their role as precursors of anti-neoplastic bisindole Catharanthus alkaloids

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