Open-angle glaucoma

scientific article published on 01 April 1993

Open-angle glaucoma is …
instance of (P31):
scholarly articleQ13442814
review articleQ7318358

External links are
P356DOI10.1056/NEJM199304153281507
P698PubMed publication ID8455668

P2093author name stringQuigley HA
P433issue15
P407language of work or nameEnglishQ1860
P304page(s)1097-1106
P577publication date1993-04-01
P1433published inThe New England Journal of MedicineQ582728
P1476titleOpen-angle glaucoma
P478volume328

Reverse relations

cites work (P2860)
Q397229312-MeS-beta,gamma-CCl2-ATP is a potent agent for reducing intraocular pressure
Q28548061A Glaucoma-Associated Variant of Optineurin, M98K, Activates Tbk1 to Enhance Autophagosome Formation and Retinal Cell Death Dependent on Ser177 Phosphorylation of Optineurin
Q33604802A genome-wide association study of optic disc parameters
Q36146045A novel MYOC heterozygous mutation identified in a Chinese Uygur pedigree with primary open-angle glaucoma.
Q37150521A spectrum of CYP1B1 mutations associated with primary congenital glaucoma in families of Pakistani descent
Q42681896A third locus (GLC1D) for adult-onset primary open-angle glaucoma maps to the 8q23 region
Q42127523Additive Intraocular Pressure-Lowering Effects of Ripasudil with Glaucoma Therapeutic Agents in Rabbits and Monkeys
Q45862094Adenoviral reporter gene transfer to the human trabecular meshwork does not alter aqueous humor outflow. Relevance for potential gene therapy of glaucoma
Q34064090Age-associated changes in the retinal nerve fiber layer and optic nerve head
Q44799120Altered secretion of a TIGR/MYOC mutant lacking the olfactomedin domain
Q33740956Analysis of microsatellite polymorphisms within the GLC1F locus in Japanese patients with normal tension glaucoma.
Q38016147Animal models of glaucoma
Q78384252Anisometropia and degree of optic nerve damage in chronic open-angle glaucoma
Q37637157Anterior lamina cribrosa surface depth, age, and visual field sensitivity in the Portland Progression Project.
Q37176896Apolipoprotein E polymorphisms and primary glaucoma in Saudis
Q37217630Apolipoprotein E-promoter single-nucleotide polymorphisms affect the phenotype of primary open-angle glaucoma and demonstrate interaction with the myocilin gene
Q42269754Apoptosis in the trabecular meshwork of glaucomatous patients
Q80406535Association between open-angle glaucoma and gene polymorphism for heat-shock protein 70-1
Q34562619Association of HK2 and NCK2 with normal tension glaucoma in the Japanese population
Q53884723Association of a single nucleotide polymorphism in the TIGR/MYOCILIN gene promoter with the severity of primary open-angle glaucoma.
Q33574079Association of toll-like receptor 2 gene polymorphisms with normal tension glaucoma
Q37087161Association study of genetic variants on chromosome 7q31 with susceptibility to normal tension glaucoma in a Japanese population.
Q46440971Autoantibodies in patients with glaucoma: a comparison of IgG serum antibodies against retinal, optic nerve, and optic nerve head antigens
Q39073674BAX to basics: How the BCL2 gene family controls the death of retinal ganglion cells
Q55092027BDNF Polymorphism: A Review of Its Diagnostic and Clinical Relevance in Neurodegenerative Disorders.
Q44284982Bimatoprost (Lumigan((R))) is an agonist at the cloned human ocular FP prostaglandin receptor: real-time FLIPR-based intracellular Ca(2+) mobilization studies
Q41735037Brimonidine. A review of its pharmacological properties and clinical potential in the management of open-angle glaucoma and ocular hypertension
Q35446694CYP1B1 mutations in French patients with early-onset primary open-angle glaucoma
Q57063816Circadian regulation in the retina: from molecules to network
Q28394939Common variants near ABCA1, AFAP1 and GMDS confer risk of primary open-angle glaucoma
Q37819720Complex genetic mechanisms in glaucoma: an overview
Q42604604Cost-effectiveness of early detection and treatment of ocular hypertension and primary open-angle glaucoma by the ophthalmologist
Q37088314Cross-talk between TGF-beta1 and IL-6 in human trabecular meshwork cells
Q37731910Crosstalk Between Transforming Growth Factor Beta-2 and Toll-Like Receptor 4 in the Trabecular Meshwork
Q27637428Crystal structure of human carbonic anhydrase II complexed with an anti-convulsant sugar sulphamate
Q39162548Curcumin, A Potential Therapeutic Candidate for Anterior Segment Eye Diseases: A Review
Q36236382Diagnostic Accuracy of Nonmydriatic Fundus Photography for the Detection of Glaucoma in Diabetic Patients
Q37363380Differences in the region- and depth-dependent microstructural organization in normal versus glaucomatous human posterior sclerae.
Q41087457Differential effects of unfolded protein response pathways on axon injury-induced death of retinal ganglion cells.
Q59127771Diffusion Tensor Imaging Detects Microstructural Differences of Visual Pathway in Patients With Primary Open-Angle Glaucoma and Ocular Hypertension
Q34299411Diving and hyperbaric ophthalmology
Q35035689Does optic nerve head surface topography change prior to loss of retinal nerve fiber layer thickness: a test of the site of injury hypothesis in experimental glaucoma
Q34989973Dogs and humans share a common susceptibility gene SRBD1 for glaucoma risk
Q33276940Dominant inheritance of retinal ganglion cell resistance to optic nerve crush in mice
Q34740091Dorzolamide. A review of its pharmacology and therapeutic potential in the management of glaucoma and ocular hypertension
Q33980604Down-regulation of GRP78 in human glaucomatous trabecular meshwork cells.
Q35196184Drug-induced glaucomas: mechanism and management
Q88869497ER stress and unfolded protein response in ocular health and disease
Q81250120Effect of CD44 suppression by antisense oligonucleotide on attachment of human trabecular meshwork cells to HA
Q37560353Effect of Refractive Correction Error on Retinal Nerve Fiber Layer Thickness: A Spectralis Optical Coherence Tomography Study
Q44186865Effect of brimonidine on patients undergoing uncontrolled IOP with beta-blockers.
Q92990866Effects of Fish n-3 PUFAs on Intestinal Microbiota and Immune System
Q36499750Effects of K-115 (Ripasudil), a novel ROCK inhibitor, on trabecular meshwork and Schlemm's canal endothelial cells
Q30955452Effects of chemical inhibition of N-WASP, a critical regulator of actin polymerization on aqueous humor outflow through the conventional pathway
Q37195549Effects of optic nerve injury, glaucoma, and neuroprotection on the survival, structure, and function of ganglion cells in the mammalian retina
Q28574168Effects of optineurin siRNA on apoptotic genes and apoptosis in RGC-5 cells
Q52714935Elevated expression of human bHLH factor ATOH7 accelerates cell cycle progression of progenitors and enhances production of avian retinal ganglion cells.
Q42461840Elevated intraocular pressure induces Rho GTPase mediated contractile signaling in the trabecular meshwork
Q34659383Emerging perspectives in glaucoma: optimizing 24-hour control of intraocular pressure
Q59799671Estimating the age of the p.Cys433Arg variant in the MYOC gene in patients with primary open-angle glaucoma
Q33678189Exclusion of one pedigree affected by adult onset primary open angle glaucoma from linkage to the juvenile glaucoma locus on chromosome 1q21-q31.
Q28207484Expression of optineurin, a glaucoma-linked gene, is influenced by elevated intraocular pressure
Q36646381Extracellular matrix in the trabecular meshwork
Q96576858Fibronectin extra domain A (FN-EDA) elevates intraocular pressure through Toll-like receptor 4 signaling
Q89536510Four-Year Outcomes of Two Second-Generation Trabecular Micro-Bypass Stents in Patients with Open-Angle Glaucoma on One Medication
Q88527962Gene expression changes in the retina after systemic administration of aldosterone
Q45873239Gene therapy using p21WAF-1/Cip-1 to modulate wound healing after glaucoma trabeculectomy surgery in a primate model of ocular hypertension
Q33679090Genetic heterogeneity of primary open angle glaucoma and ocular hypertension: linkage to GLC1A associated with an increased risk of severe glaucomatous optic neuropathy
Q53889747Genetic linkage of autosomal dominant primary open angle glaucoma to chromosome 3q in a Greek pedigree.
Q39010214Genetic variants associated with primary open angle glaucoma in Indian population
Q27022047Genetic, Biochemical and Clinical Insights into Primary Congenital Glaucoma
Q42126987Genome-wide expression profile of human trabecular meshwork cultured cells, nonglaucomatous and primary open angle glaucoma tissue.
Q34208353Genotyping HLA-DRB1 and HLA-DQB1 alleles in Japanese patients with normal tension glaucoma.
Q64125124Glaucoma Pred: Glaucoma prediction based on Myocilin genotype and phenotype information
Q64975164Glaucoma Symptom Scale: Psychometric properties of the Serbian version.
Q33392705Glaucoma alters the circadian timing system
Q33607810H-1152 effects on intraocular pressure and trabecular meshwork morphology of rat eyes
Q37292402Heterozygous Pitx2 Null Mice Accurately Recapitulate the Ocular Features of Axenfeld-Rieger Syndrome and Congenital Glaucoma
Q44635119Human Ciliary Muscle Cell Responses to FP-Class Prostaglandin Analogs: Phosphoinositide Hydrolysis, Intracellular Ca2+ Mobilization and MAP Kinase Activation
Q42016872Human retina contains polyamine sensitive [3H]-ifenprodil binding sites: implications for neuroprotection?
Q74176266Human, bovine, and rabbit retinal glutamate-induced [3H]D-aspartate release: role in excitotoxicity
Q37487616Identification of Mutations in Myocilin and Beta-1,4-galactosyltransferase 3 Genes in a Chinese Family with Primary Open-angle Glaucoma
Q42689802Identification of genes associated with primary open-angle glaucoma by bioinformatics approach
Q90206205Immune Mediated Degeneration and Possible Protection in Glaucoma
Q49992681Impact of the clinical use of ROCK inhibitor on the pathogenesis and treatment of glaucoma
Q36458667Increased expression of the WNT antagonist sFRP-1 in glaucoma elevates intraocular pressure
Q72395545Increased incidence of paraproteinemia and autoantibodies in patients with normal-pressure glaucoma
Q35553296Increased prevalence of ocular glaucomatous abnormalities in systemic sclerosis
Q37195253Induced autoimmunity to heat shock proteins elicits glaucomatous loss of retinal ganglion cell neurons via activated T-cell-derived fas-ligand
Q42859421Induction of IL-6 expression by mechanical stress in the trabecular meshwork
Q35128563Induction of TGF-beta1 in the trabecular meshwork under cyclic mechanical stress
Q34848918Investigation of the association between SLC1A3 gene polymorphisms and normal tension glaucoma
Q37257670Investigation of the association between the GLC3A locus and normal tension glaucoma in Japanese patients by microsatellite analysis
Q28081361In vivo imaging methods to assess glaucomatous optic neuropathy
Q47100438Isoform-selective Hsp90 inhibition rescues model of hereditary open-angle glaucoma
Q34756956Lamina cribrosa defects and optic disc morphology in primary open angle glaucoma with high myopia
Q34407754Latanoprost. A review of its pharmacological properties, clinical efficacy and tolerability in the management of primary open-angle glaucoma and ocular hypertension
Q35153670Lentiviral mediated gene delivery to the anterior chamber of rodent eyes
Q40825170Linking structure and function in glaucoma
Q24538831Localization of the fourth locus (GLC1E) for adult-onset primary open-angle glaucoma to the 10p15-p14 region
Q37396161Longitudinal evaluation of retinal ganglion cell function and IOP in the DBA/2J mouse model of glaucoma
Q84865766Luminance-modulated adaptation in the global flash mfERG: a preliminary study of early retinal functional changes in high-risk glaucoma patients
Q36896726Mapping 3D Strains with Ultrasound Speckle Tracking: Method Validation and Initial Results in Porcine Scleral Inflation
Q37678801Molecular complexity of primary open angle glaucoma: current concepts
Q34057605Molecular genetics of primary congenital glaucoma
Q47212698Mutual regulation of the Hippo/Wnt/LPA/TGF‑β signaling pathways and their roles in glaucoma (Review).
Q48221630Müller glia cells activation in rat retina after optic nerve injury: spatiotemporal correlation with transcription initiation factor IIb.
Q37420927Netarsudil Increases Outflow Facility in Human Eyes Through Multiple Mechanisms
Q34976640Neurobiology of glaucomatous optic neuropathy: diverse cellular events in neurodegeneration and neuroprotection
Q40827206Neuronal death in glaucoma
Q43732143Neuroprotective effect of alpha(2) agonist (brimonidine) on adult rat retinal ganglion cells after increased intraocular pressure
Q24809641Neurotrophin and Trk expression by cells of the human lamina cribrosa following oxygen-glucose deprivation
Q35736309Non-housekeeping genes expressed in human trabecular meshwork cell cultures
Q37320324Number of people with glaucoma worldwide
Q52325561OCTA vessel density changes in the macular zone in glaucomatous eyes.
Q36479235Ophthaproblem. Glaucomatous damage.
Q36467214Optimizing the information yield of 3-D OCT in glaucoma
Q96136419Optogenetic stimulation of phosphoinositides reveals a critical role of primary cilia in eye pressure regulation
Q33608579Optometrists referrals for glaucoma assessment: a prospective survey of clinical data and outcomes
Q33805835Pharmacological and ocular hypotensive properties of topical carbonic anhydrase inhibitors
Q34452905Polymorphisms in an intronic region of the myocilin gene associated with primary open-angle glaucoma--a possible role for alternate splicing.
Q35204776Primary open angle glaucoma. The need for a consensus case definition
Q37166653Pro370Leu mutant myocilin impairs mitochondrial functions in human trabecular meshwork cells.
Q33259237Progressive ganglion cell loss and optic nerve degeneration in DBA/2J mice is variable and asymmetric
Q40834293Prospects for genetic intervention in primary open-angle glaucoma
Q44539005Proteasome inhibition by chronic oxidative stress in human trabecular meshwork cells
Q35676010Protective effect of 14-3-3 antibodies on stressed neuroretinal cells via the mitochondrial apoptosis pathway
Q35584898Recent advances in molecular genetics of glaucoma.
Q34936761Retinal nerve fiber layer assessment: area versus thickness measurements from elliptical scans centered on the optic nerve
Q55220109Risk of developing open-angle glaucoma in patients with carotid artery stenosis: A nationwide cohort study.
Q42665102Risk of ocular hypertension or open-angle glaucoma in elderly patients on oral glucocorticoids
Q38761751Role of ID Proteins in BMP4 Inhibition of Profibrotic Effects of TGF-β2 in Human TM Cells
Q36676552Role of substratum stiffness in modulating genes associated with extracellular matrix and mechanotransducers YAP and TAZ
Q35060902Role of the APOE ε2/ε3/ε4 polymorphism in the development of primary open-angle glaucoma: evidence from a comprehensive meta-analysis
Q38688358Roles of exosomes in the normal and diseased eye.
Q33222118Screening for primary open-angle glaucoma in the developed world: are we there yet?
Q36083707Screening for primary open-angle glaucoma in the primary care setting: an update for the US preventive services task force
Q42672961Selection of controls in database case-control studies: glucocorticoids and the risk of glaucoma
Q35027124Sequence analysis of MYOC and CYP1B1 in a Chinese pedigree of primary open-angle glaucoma.
Q64280813Silicone oil-induced ocular hypertension and glaucomatous neurodegeneration in mouse
Q42927626Single-nucleotide polymorphisms and glaucoma severity
Q37494344Smad3 is necessary for transforming growth factor-beta2 induced ocular hypertension in mice
Q48891863Spatiotemporal expression of postsynaptic density 95 in rat retina after optic nerve injury
Q37195933Specialized podosome- or invadopodia-like structures (PILS) for focal trabecular meshwork extracellular matrix turnover
Q35153678Specific targeting of gene expression to a subset of human trabecular meshwork cells using the chitinase 3-like 1 promoter
Q39235894Stem cell therapies for retinal diseases: recapitulating development to replace degenerated cells
Q26860040Stem cells, retinal ganglion cells and glaucoma
Q34313669Structure-function relations of parasol cells in the normal and glaucomatous primate retina
Q42106707Structures of murine carbonic anhydrase IV and human carbonic anhydrase II complexed with brinzolamide: molecular basis of isozyme-drug discrimination
Q35744346Study on establishment and mechanics application of finite element model of bovine eye.
Q28580190Synucleins in glaucoma: implication of gamma-synuclein in glaucomatous alterations in the optic nerve
Q91657604Systematic reviews and randomised controlled trials on open angle glaucoma
Q35944216The Effect of Attentional Cueing and Spatial Uncertainty in Visual Field Testing
Q35999823The Potential of Human Stem Cells for the Study and Treatment of Glaucoma.
Q38263876The Trabecular Meshwork: A Basic Review of Form and Function
Q38226119The complex role of neuroinflammation in glaucoma
Q34077810The evaluation of the oxidative stress parameters in patients with primary angle-closure glaucoma
Q34258714The formation of cortical actin arrays in human trabecular meshwork cells in response to cytoskeletal disruption
Q77429280The intact isolated (ex vivo) retina as a model system for the study of excitotoxicity
Q36021030The intrinsic stiffness of human trabecular meshwork cells increases with senescence.
Q34422963The ocular hypotensive effect of saffron extract in primary open angle glaucoma: a pilot study
Q37188085The papilla as screening parameter for early diagnosis of glaucoma
Q34831407The post-illumination pupil response is reduced in glaucoma patients.
Q34674415The receptive fields of cat retinal ganglion cells in physiological and pathological states: where we are after half a century of research
Q34426325The relationship between retinal nerve fiber layer thickness and optic nerve head neuroretinal rim tissue in glaucoma
Q35769259The rising cost of glaucoma drugs in Ireland 1996-2003
Q34655173Topical bimatoprost: a review of its use in open-angle glaucoma and ocular hypertension
Q33859626Trans-lamina cribrosa pressure difference correlated with neuroretinal rim area in glaucoma
Q53030850Up-regulation of SKIP relates to retinal ganglion cells apoptosis after optic nerve crush in vivo.
Q55073618Upregulation of Gem relates to retinal ganglion cells apoptosis after optic nerve crush in adult rats.
Q41589135Use of isolated ocular arteries in vitro to define the pathology of vascular changes in glaucoma
Q42676161Using the Utah Population Database to assess familial risk of primary open angle glaucoma
Q42692880Validity of code based algorithms to identify primary open angle glaucoma (POAG) in Veterans Affairs (VA) administrative databases
Q34572830Visual field defects and neural losses from experimental glaucoma
Q36490953Visual field defects and retinal ganglion cell losses in patients with glaucoma
Q30429628What do mechanotransduction, Hippo, Wnt, and TGFβ have in common? YAP and TAZ as key orchestrating molecules in ocular health and disease
Q22305443What was Glaucoma Called Before the 20th Century?
Q72164985Whole-blood pharmacokinetics and metabolic effects of the topical carbonic anhydrase inhibitor dorzolamide
Q35155798Wnt inhibition induces persistent increases in intrinsic stiffness of human trabecular meshwork cells
Q35111136γ-Synuclein antibodies have neuroprotective potential on neuroretinal cells via proteins of the mitochondrial apoptosis pathway

Search more.