scholarly article | Q13442814 |
review article | Q7318358 |
P356 | DOI | 10.1056/NEJM199304153281507 |
P698 | PubMed publication ID | 8455668 |
P2093 | author name string | Quigley HA | |
P433 | issue | 15 | |
P407 | language of work or name | English | Q1860 |
P304 | page(s) | 1097-1106 | |
P577 | publication date | 1993-04-01 | |
P1433 | published in | The New England Journal of Medicine | Q582728 |
P1476 | title | Open-angle glaucoma | |
P478 | volume | 328 |
Q39722931 | 2-MeS-beta,gamma-CCl2-ATP is a potent agent for reducing intraocular pressure |
Q28548061 | A Glaucoma-Associated Variant of Optineurin, M98K, Activates Tbk1 to Enhance Autophagosome Formation and Retinal Cell Death Dependent on Ser177 Phosphorylation of Optineurin |
Q33604802 | A genome-wide association study of optic disc parameters |
Q36146045 | A novel MYOC heterozygous mutation identified in a Chinese Uygur pedigree with primary open-angle glaucoma. |
Q37150521 | A spectrum of CYP1B1 mutations associated with primary congenital glaucoma in families of Pakistani descent |
Q42681896 | A third locus (GLC1D) for adult-onset primary open-angle glaucoma maps to the 8q23 region |
Q42127523 | Additive Intraocular Pressure-Lowering Effects of Ripasudil with Glaucoma Therapeutic Agents in Rabbits and Monkeys |
Q45862094 | Adenoviral reporter gene transfer to the human trabecular meshwork does not alter aqueous humor outflow. Relevance for potential gene therapy of glaucoma |
Q34064090 | Age-associated changes in the retinal nerve fiber layer and optic nerve head |
Q44799120 | Altered secretion of a TIGR/MYOC mutant lacking the olfactomedin domain |
Q33740956 | Analysis of microsatellite polymorphisms within the GLC1F locus in Japanese patients with normal tension glaucoma. |
Q38016147 | Animal models of glaucoma |
Q78384252 | Anisometropia and degree of optic nerve damage in chronic open-angle glaucoma |
Q37637157 | Anterior lamina cribrosa surface depth, age, and visual field sensitivity in the Portland Progression Project. |
Q37176896 | Apolipoprotein E polymorphisms and primary glaucoma in Saudis |
Q37217630 | Apolipoprotein E-promoter single-nucleotide polymorphisms affect the phenotype of primary open-angle glaucoma and demonstrate interaction with the myocilin gene |
Q42269754 | Apoptosis in the trabecular meshwork of glaucomatous patients |
Q80406535 | Association between open-angle glaucoma and gene polymorphism for heat-shock protein 70-1 |
Q34562619 | Association of HK2 and NCK2 with normal tension glaucoma in the Japanese population |
Q53884723 | Association of a single nucleotide polymorphism in the TIGR/MYOCILIN gene promoter with the severity of primary open-angle glaucoma. |
Q33574079 | Association of toll-like receptor 2 gene polymorphisms with normal tension glaucoma |
Q37087161 | Association study of genetic variants on chromosome 7q31 with susceptibility to normal tension glaucoma in a Japanese population. |
Q46440971 | Autoantibodies in patients with glaucoma: a comparison of IgG serum antibodies against retinal, optic nerve, and optic nerve head antigens |
Q39073674 | BAX to basics: How the BCL2 gene family controls the death of retinal ganglion cells |
Q55092027 | BDNF Polymorphism: A Review of Its Diagnostic and Clinical Relevance in Neurodegenerative Disorders. |
Q44284982 | Bimatoprost (Lumigan((R))) is an agonist at the cloned human ocular FP prostaglandin receptor: real-time FLIPR-based intracellular Ca(2+) mobilization studies |
Q41735037 | Brimonidine. A review of its pharmacological properties and clinical potential in the management of open-angle glaucoma and ocular hypertension |
Q35446694 | CYP1B1 mutations in French patients with early-onset primary open-angle glaucoma |
Q57063816 | Circadian regulation in the retina: from molecules to network |
Q28394939 | Common variants near ABCA1, AFAP1 and GMDS confer risk of primary open-angle glaucoma |
Q37819720 | Complex genetic mechanisms in glaucoma: an overview |
Q42604604 | Cost-effectiveness of early detection and treatment of ocular hypertension and primary open-angle glaucoma by the ophthalmologist |
Q37088314 | Cross-talk between TGF-beta1 and IL-6 in human trabecular meshwork cells |
Q37731910 | Crosstalk Between Transforming Growth Factor Beta-2 and Toll-Like Receptor 4 in the Trabecular Meshwork |
Q27637428 | Crystal structure of human carbonic anhydrase II complexed with an anti-convulsant sugar sulphamate |
Q39162548 | Curcumin, A Potential Therapeutic Candidate for Anterior Segment Eye Diseases: A Review |
Q36236382 | Diagnostic Accuracy of Nonmydriatic Fundus Photography for the Detection of Glaucoma in Diabetic Patients |
Q37363380 | Differences in the region- and depth-dependent microstructural organization in normal versus glaucomatous human posterior sclerae. |
Q41087457 | Differential effects of unfolded protein response pathways on axon injury-induced death of retinal ganglion cells. |
Q59127771 | Diffusion Tensor Imaging Detects Microstructural Differences of Visual Pathway in Patients With Primary Open-Angle Glaucoma and Ocular Hypertension |
Q34299411 | Diving and hyperbaric ophthalmology |
Q35035689 | Does optic nerve head surface topography change prior to loss of retinal nerve fiber layer thickness: a test of the site of injury hypothesis in experimental glaucoma |
Q34989973 | Dogs and humans share a common susceptibility gene SRBD1 for glaucoma risk |
Q33276940 | Dominant inheritance of retinal ganglion cell resistance to optic nerve crush in mice |
Q34740091 | Dorzolamide. A review of its pharmacology and therapeutic potential in the management of glaucoma and ocular hypertension |
Q33980604 | Down-regulation of GRP78 in human glaucomatous trabecular meshwork cells. |
Q35196184 | Drug-induced glaucomas: mechanism and management |
Q88869497 | ER stress and unfolded protein response in ocular health and disease |
Q81250120 | Effect of CD44 suppression by antisense oligonucleotide on attachment of human trabecular meshwork cells to HA |
Q37560353 | Effect of Refractive Correction Error on Retinal Nerve Fiber Layer Thickness: A Spectralis Optical Coherence Tomography Study |
Q44186865 | Effect of brimonidine on patients undergoing uncontrolled IOP with beta-blockers. |
Q92990866 | Effects of Fish n-3 PUFAs on Intestinal Microbiota and Immune System |
Q36499750 | Effects of K-115 (Ripasudil), a novel ROCK inhibitor, on trabecular meshwork and Schlemm's canal endothelial cells |
Q30955452 | Effects of chemical inhibition of N-WASP, a critical regulator of actin polymerization on aqueous humor outflow through the conventional pathway |
Q37195549 | Effects of optic nerve injury, glaucoma, and neuroprotection on the survival, structure, and function of ganglion cells in the mammalian retina |
Q28574168 | Effects of optineurin siRNA on apoptotic genes and apoptosis in RGC-5 cells |
Q52714935 | Elevated expression of human bHLH factor ATOH7 accelerates cell cycle progression of progenitors and enhances production of avian retinal ganglion cells. |
Q42461840 | Elevated intraocular pressure induces Rho GTPase mediated contractile signaling in the trabecular meshwork |
Q34659383 | Emerging perspectives in glaucoma: optimizing 24-hour control of intraocular pressure |
Q59799671 | Estimating the age of the p.Cys433Arg variant in the MYOC gene in patients with primary open-angle glaucoma |
Q33678189 | Exclusion of one pedigree affected by adult onset primary open angle glaucoma from linkage to the juvenile glaucoma locus on chromosome 1q21-q31. |
Q28207484 | Expression of optineurin, a glaucoma-linked gene, is influenced by elevated intraocular pressure |
Q36646381 | Extracellular matrix in the trabecular meshwork |
Q96576858 | Fibronectin extra domain A (FN-EDA) elevates intraocular pressure through Toll-like receptor 4 signaling |
Q89536510 | Four-Year Outcomes of Two Second-Generation Trabecular Micro-Bypass Stents in Patients with Open-Angle Glaucoma on One Medication |
Q88527962 | Gene expression changes in the retina after systemic administration of aldosterone |
Q45873239 | Gene therapy using p21WAF-1/Cip-1 to modulate wound healing after glaucoma trabeculectomy surgery in a primate model of ocular hypertension |
Q33679090 | Genetic heterogeneity of primary open angle glaucoma and ocular hypertension: linkage to GLC1A associated with an increased risk of severe glaucomatous optic neuropathy |
Q53889747 | Genetic linkage of autosomal dominant primary open angle glaucoma to chromosome 3q in a Greek pedigree. |
Q39010214 | Genetic variants associated with primary open angle glaucoma in Indian population |
Q27022047 | Genetic, Biochemical and Clinical Insights into Primary Congenital Glaucoma |
Q42126987 | Genome-wide expression profile of human trabecular meshwork cultured cells, nonglaucomatous and primary open angle glaucoma tissue. |
Q34208353 | Genotyping HLA-DRB1 and HLA-DQB1 alleles in Japanese patients with normal tension glaucoma. |
Q64125124 | Glaucoma Pred: Glaucoma prediction based on Myocilin genotype and phenotype information |
Q64975164 | Glaucoma Symptom Scale: Psychometric properties of the Serbian version. |
Q33392705 | Glaucoma alters the circadian timing system |
Q33607810 | H-1152 effects on intraocular pressure and trabecular meshwork morphology of rat eyes |
Q37292402 | Heterozygous Pitx2 Null Mice Accurately Recapitulate the Ocular Features of Axenfeld-Rieger Syndrome and Congenital Glaucoma |
Q44635119 | Human Ciliary Muscle Cell Responses to FP-Class Prostaglandin Analogs: Phosphoinositide Hydrolysis, Intracellular Ca2+ Mobilization and MAP Kinase Activation |
Q42016872 | Human retina contains polyamine sensitive [3H]-ifenprodil binding sites: implications for neuroprotection? |
Q74176266 | Human, bovine, and rabbit retinal glutamate-induced [3H]D-aspartate release: role in excitotoxicity |
Q37487616 | Identification of Mutations in Myocilin and Beta-1,4-galactosyltransferase 3 Genes in a Chinese Family with Primary Open-angle Glaucoma |
Q42689802 | Identification of genes associated with primary open-angle glaucoma by bioinformatics approach |
Q90206205 | Immune Mediated Degeneration and Possible Protection in Glaucoma |
Q49992681 | Impact of the clinical use of ROCK inhibitor on the pathogenesis and treatment of glaucoma |
Q36458667 | Increased expression of the WNT antagonist sFRP-1 in glaucoma elevates intraocular pressure |
Q72395545 | Increased incidence of paraproteinemia and autoantibodies in patients with normal-pressure glaucoma |
Q35553296 | Increased prevalence of ocular glaucomatous abnormalities in systemic sclerosis |
Q37195253 | Induced autoimmunity to heat shock proteins elicits glaucomatous loss of retinal ganglion cell neurons via activated T-cell-derived fas-ligand |
Q42859421 | Induction of IL-6 expression by mechanical stress in the trabecular meshwork |
Q35128563 | Induction of TGF-beta1 in the trabecular meshwork under cyclic mechanical stress |
Q34848918 | Investigation of the association between SLC1A3 gene polymorphisms and normal tension glaucoma |
Q37257670 | Investigation of the association between the GLC3A locus and normal tension glaucoma in Japanese patients by microsatellite analysis |
Q28081361 | In vivo imaging methods to assess glaucomatous optic neuropathy |
Q47100438 | Isoform-selective Hsp90 inhibition rescues model of hereditary open-angle glaucoma |
Q34756956 | Lamina cribrosa defects and optic disc morphology in primary open angle glaucoma with high myopia |
Q34407754 | Latanoprost. A review of its pharmacological properties, clinical efficacy and tolerability in the management of primary open-angle glaucoma and ocular hypertension |
Q35153670 | Lentiviral mediated gene delivery to the anterior chamber of rodent eyes |
Q40825170 | Linking structure and function in glaucoma |
Q24538831 | Localization of the fourth locus (GLC1E) for adult-onset primary open-angle glaucoma to the 10p15-p14 region |
Q37396161 | Longitudinal evaluation of retinal ganglion cell function and IOP in the DBA/2J mouse model of glaucoma |
Q84865766 | Luminance-modulated adaptation in the global flash mfERG: a preliminary study of early retinal functional changes in high-risk glaucoma patients |
Q36896726 | Mapping 3D Strains with Ultrasound Speckle Tracking: Method Validation and Initial Results in Porcine Scleral Inflation |
Q37678801 | Molecular complexity of primary open angle glaucoma: current concepts |
Q34057605 | Molecular genetics of primary congenital glaucoma |
Q47212698 | Mutual regulation of the Hippo/Wnt/LPA/TGF‑β signaling pathways and their roles in glaucoma (Review). |
Q48221630 | Müller glia cells activation in rat retina after optic nerve injury: spatiotemporal correlation with transcription initiation factor IIb. |
Q37420927 | Netarsudil Increases Outflow Facility in Human Eyes Through Multiple Mechanisms |
Q34976640 | Neurobiology of glaucomatous optic neuropathy: diverse cellular events in neurodegeneration and neuroprotection |
Q40827206 | Neuronal death in glaucoma |
Q43732143 | Neuroprotective effect of alpha(2) agonist (brimonidine) on adult rat retinal ganglion cells after increased intraocular pressure |
Q24809641 | Neurotrophin and Trk expression by cells of the human lamina cribrosa following oxygen-glucose deprivation |
Q35736309 | Non-housekeeping genes expressed in human trabecular meshwork cell cultures |
Q37320324 | Number of people with glaucoma worldwide |
Q52325561 | OCTA vessel density changes in the macular zone in glaucomatous eyes. |
Q36479235 | Ophthaproblem. Glaucomatous damage. |
Q36467214 | Optimizing the information yield of 3-D OCT in glaucoma |
Q96136419 | Optogenetic stimulation of phosphoinositides reveals a critical role of primary cilia in eye pressure regulation |
Q33608579 | Optometrists referrals for glaucoma assessment: a prospective survey of clinical data and outcomes |
Q33805835 | Pharmacological and ocular hypotensive properties of topical carbonic anhydrase inhibitors |
Q34452905 | Polymorphisms in an intronic region of the myocilin gene associated with primary open-angle glaucoma--a possible role for alternate splicing. |
Q35204776 | Primary open angle glaucoma. The need for a consensus case definition |
Q37166653 | Pro370Leu mutant myocilin impairs mitochondrial functions in human trabecular meshwork cells. |
Q33259237 | Progressive ganglion cell loss and optic nerve degeneration in DBA/2J mice is variable and asymmetric |
Q40834293 | Prospects for genetic intervention in primary open-angle glaucoma |
Q44539005 | Proteasome inhibition by chronic oxidative stress in human trabecular meshwork cells |
Q35676010 | Protective effect of 14-3-3 antibodies on stressed neuroretinal cells via the mitochondrial apoptosis pathway |
Q35584898 | Recent advances in molecular genetics of glaucoma. |
Q34936761 | Retinal nerve fiber layer assessment: area versus thickness measurements from elliptical scans centered on the optic nerve |
Q55220109 | Risk of developing open-angle glaucoma in patients with carotid artery stenosis: A nationwide cohort study. |
Q42665102 | Risk of ocular hypertension or open-angle glaucoma in elderly patients on oral glucocorticoids |
Q38761751 | Role of ID Proteins in BMP4 Inhibition of Profibrotic Effects of TGF-β2 in Human TM Cells |
Q36676552 | Role of substratum stiffness in modulating genes associated with extracellular matrix and mechanotransducers YAP and TAZ |
Q35060902 | Role of the APOE ε2/ε3/ε4 polymorphism in the development of primary open-angle glaucoma: evidence from a comprehensive meta-analysis |
Q38688358 | Roles of exosomes in the normal and diseased eye. |
Q33222118 | Screening for primary open-angle glaucoma in the developed world: are we there yet? |
Q36083707 | Screening for primary open-angle glaucoma in the primary care setting: an update for the US preventive services task force |
Q42672961 | Selection of controls in database case-control studies: glucocorticoids and the risk of glaucoma |
Q35027124 | Sequence analysis of MYOC and CYP1B1 in a Chinese pedigree of primary open-angle glaucoma. |
Q64280813 | Silicone oil-induced ocular hypertension and glaucomatous neurodegeneration in mouse |
Q42927626 | Single-nucleotide polymorphisms and glaucoma severity |
Q37494344 | Smad3 is necessary for transforming growth factor-beta2 induced ocular hypertension in mice |
Q48891863 | Spatiotemporal expression of postsynaptic density 95 in rat retina after optic nerve injury |
Q37195933 | Specialized podosome- or invadopodia-like structures (PILS) for focal trabecular meshwork extracellular matrix turnover |
Q35153678 | Specific targeting of gene expression to a subset of human trabecular meshwork cells using the chitinase 3-like 1 promoter |
Q39235894 | Stem cell therapies for retinal diseases: recapitulating development to replace degenerated cells |
Q26860040 | Stem cells, retinal ganglion cells and glaucoma |
Q34313669 | Structure-function relations of parasol cells in the normal and glaucomatous primate retina |
Q42106707 | Structures of murine carbonic anhydrase IV and human carbonic anhydrase II complexed with brinzolamide: molecular basis of isozyme-drug discrimination |
Q35744346 | Study on establishment and mechanics application of finite element model of bovine eye. |
Q28580190 | Synucleins in glaucoma: implication of gamma-synuclein in glaucomatous alterations in the optic nerve |
Q91657604 | Systematic reviews and randomised controlled trials on open angle glaucoma |
Q35944216 | The Effect of Attentional Cueing and Spatial Uncertainty in Visual Field Testing |
Q35999823 | The Potential of Human Stem Cells for the Study and Treatment of Glaucoma. |
Q38263876 | The Trabecular Meshwork: A Basic Review of Form and Function |
Q38226119 | The complex role of neuroinflammation in glaucoma |
Q34077810 | The evaluation of the oxidative stress parameters in patients with primary angle-closure glaucoma |
Q34258714 | The formation of cortical actin arrays in human trabecular meshwork cells in response to cytoskeletal disruption |
Q77429280 | The intact isolated (ex vivo) retina as a model system for the study of excitotoxicity |
Q36021030 | The intrinsic stiffness of human trabecular meshwork cells increases with senescence. |
Q34422963 | The ocular hypotensive effect of saffron extract in primary open angle glaucoma: a pilot study |
Q37188085 | The papilla as screening parameter for early diagnosis of glaucoma |
Q34831407 | The post-illumination pupil response is reduced in glaucoma patients. |
Q34674415 | The receptive fields of cat retinal ganglion cells in physiological and pathological states: where we are after half a century of research |
Q34426325 | The relationship between retinal nerve fiber layer thickness and optic nerve head neuroretinal rim tissue in glaucoma |
Q35769259 | The rising cost of glaucoma drugs in Ireland 1996-2003 |
Q34655173 | Topical bimatoprost: a review of its use in open-angle glaucoma and ocular hypertension |
Q33859626 | Trans-lamina cribrosa pressure difference correlated with neuroretinal rim area in glaucoma |
Q53030850 | Up-regulation of SKIP relates to retinal ganglion cells apoptosis after optic nerve crush in vivo. |
Q55073618 | Upregulation of Gem relates to retinal ganglion cells apoptosis after optic nerve crush in adult rats. |
Q41589135 | Use of isolated ocular arteries in vitro to define the pathology of vascular changes in glaucoma |
Q42676161 | Using the Utah Population Database to assess familial risk of primary open angle glaucoma |
Q42692880 | Validity of code based algorithms to identify primary open angle glaucoma (POAG) in Veterans Affairs (VA) administrative databases |
Q34572830 | Visual field defects and neural losses from experimental glaucoma |
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