Serine protease inhibitors block priming of monocytes for enhanced release of superoxide

scientific article published on 01 December 1995

Serine protease inhibitors block priming of monocytes for enhanced release of superoxide is …
instance of (P31):
scholarly articleQ13442814

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P698PubMed publication ID8567031

P2093author name stringM J Pabst
P Megyeri
K M Pabst
P2860cites workSynthesis and release of platelet-activating factor is inhibited by plasma alpha 1-proteinase inhibitor or alpha 1-antichymotrypsin and is stimulated by proteinasesQ24682349
Inhibition of human neutrophil superoxide generation by alpha 1-antichymotrypsinQ28645835
Rapid proteolysis of I kappa B-alpha is necessary for activation of transcription factor NF-kappa BQ29618193
Lipopolysaccharide priming of human neutrophils for an enhanced respiratory burst. Role of intracellular free calciumQ34563678
Studies of the effect of a platelet-activating factor antagonist, CL 184,005, in animal models of gram-negative bacterial sepsisQ35897129
Increased production of superoxide anion by macrophages exposed in vitro to muramyl dipeptide or lipopolysaccharideQ36343222
Priming of macrophages for enhanced oxidative metabolism by exposure to proteolytic enzymesQ36344839
Identification of interferon-gamma as the lymphokine that activates human macrophage oxidative metabolism and antimicrobial activityQ36348121
Priming of neutrophils for enhanced release of oxygen metabolites by bacterial lipopolysaccharide. Evidence for increased activity of the superoxide-producing enzymeQ36349700
Gram-negative endotoxin: an extraordinary lipid with profound effects on eukaryotic signal transduction.Q37374764
Neither CD14 nor serum is absolutely necessary for activation of mononuclear phagocytes by bacterial lipopolysaccharideQ40269153
The inducible transcription factor NF-kappa B: structure-function relationship of its protein subunitsQ40885991
Proteolytic processing of NF-kappa B/I kappa B in human monocytes. ATP-dependent induction by pro-inflammatory mediatorsQ41381486
Regulation of NF-?B activity in murine macrophages: Effect of bacterial lipopolysaccharide and phorbol esterQ41644736
The chymotrypsin inhibitor carbobenzyloxy-leucine-tyrosine-chloromethylketone interferes with the neutrophil respiratory burst mediated by a signaling pathway independent of PtdInsP2 breakdown and cytosolic free calciumQ41788206
Reaction of serine proteases with substituted isocoumarins: discovery of 3,4-dichloroisocoumarin, a new general mechanism based serine protease inhibitorQ42225238
Recombinant human monocyte IL-8 primes NADPH-oxidase and phospholipase A2 activation in human neutrophilsQ44020592
Effect of synthetic protease inhibitors on superoxide (O2-), hydrogen peroxide (H2O2) and hydroxyl radical production by human polymorphonuclear leukocytesQ45002093
Synthetic low molecular weight inhibitors of serum kallikreinQ47357255
Alpha-1-antichymotrypsin inhibits the NADPH oxidase-enzyme complex in phorbol ester-stimulated neutrophil membranesQ48827415
Inhibition of neutrophil superoxide production by human plasma α1 -antitrypsinQ57925662
Neutrophil responses to lipopolysaccharide. Effect of adherence on triggering and priming of the respiratory burstQ67912766
Effect of Legionella pneumophila cytotoxic protease on human neutrophil and monocyte functionQ68122626
Priming of neutrophils by lipopolysaccharide for enhanced release of superoxide. Requirement for plasma but not for tumor necrosis factor-alphaQ68480090
The priming of neutrophils by lipopolysaccharide for production of intracellular platelet-activating factor. Potential role in mediation of enhanced superoxide secretionQ69824717
Macrophage membrane proteins: possible role in the regulation of priming for enhanced respiratory burst activityQ70160745
Enhanced release of oxygen metabolites by monocyte-derived macrophages exposed to proteolytic enzymes: activity of neutrophil elastase and cathepsin GQ72390151
Cultured human monocytes require exposure to bacterial products to maintain an optimal oxygen radical responseQ72918207
P433issue4
P304page(s)629-635
P577publication date1995-12-01
P1433published inImmunologyQ15754984
P1476titleSerine protease inhibitors block priming of monocytes for enhanced release of superoxide
P478volume86

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cites work (P2860)
Q33290046Association of specific proteolytic processing of bone sialoprotein and bone acidic glycoprotein-75 with mineralization within biomineralization foci
Q50529517C2-ceramide and C6-ceramide inhibited priming for enhanced release of superoxide in monocytes, but had no effect on the killing of leukaemic cells by monocytes.
Q33887938Gelatin degradation assay reveals MMP-9 inhibitors and function of O-glycosylated domain
Q38848036Proteome of monocyte priming by lipopolysaccharide, including changes in interleukin-1beta and leukocyte elastase inhibitor
Q42840855Reactive oxygen species generation by the ethylene-bis-dithiocarbamate (EBDC) fungicide mancozeb and its contribution to neuronal toxicity in mesencephalic cells
Q38694691Respiratory syncytial virus (RSV) entry is inhibited by serine protease inhibitor AEBSF when present during an early stage of infection.
Q33901176Serine protease inhibition attenuates rIL-12-induced GZMA activity and proinflammatory events by modulating the Th2 profile from estrogen-treated mice.
Q31075878Serine protease inhibitor attenuates ovalbumin induced inflammation in mouse model of allergic airway disease

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