Warfarin inhibition of vitamin K 2,3-epoxide reductase in rat liver microsomes

scientific article published on 01 November 1983

Warfarin inhibition of vitamin K 2,3-epoxide reductase in rat liver microsomes is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1021/BI00293A031
P698PubMed publication ID6652076

P2093author name stringM J Fasco
P A Friedman
L M Principe
W A Walsh
P433issue24
P407language of work or nameEnglishQ1860
P921main subjectvitamin KQ182338
(E)-phytonadioneQ186093
(RS)-warfarinQ407431
P1104number of pages6
P304page(s)5655-5660
P577publication date1983-11-01
P1433published inBiochemistryQ764876
P1476titleWarfarin inhibition of vitamin K 2,3-epoxide reductase in rat liver microsomes
P478volume22

Reverse relations

cites work (P2860)
Q73853938Assembly of the warfarin-sensitive vitamin K 2,3-epoxide reductase enzyme complex in the endoplasmic reticulum membrane
Q52477325Is thioredoxin the physiological vitamin K epoxide reducing agent?
Q41862955Microsomal lipoamide reductase provides vitamin K epoxide reductase with reducing equivalents
Q28242581Mutations in VKORC1 cause warfarin resistance and multiple coagulation factor deficiency type 2
Q33364524New pieces to an old puzzle: identifying the warfarin-binding site that prevents clotting
Q24304387Novel insight into the mechanism of the vitamin K oxidoreductase (VKOR): electron relay through Cys43 and Cys51 reduces VKOR to allow vitamin K reduction and facilitation of vitamin K-dependent protein carboxylation
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Q39761459Recent advances in hepatic vitamin K metabolism and function
Q70407705Reduced thioredoxin: a possible physiological cofactor for vitamin K epoxide reductase. Further support for an active site disulfide
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Q52582864Stabilization of warfarin-binding pocket of VKORC1 and VKORL1 by a peripheral region determines their different sensitivity to warfarin inhibition.
Q26796613Structural Modeling Insights into Human VKORC1 Phenotypes
Q37122098Structure and function of vitamin K epoxide reductase
Q73854557The characterization of potent novel warfarin analogs
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Q42062867Warfarin poisoning and vitamin K antagonism in rat and human liver. Design of a system in vitro that mimics the situation in vivo
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Q29644511Warfarin: history, tautomerism and activity
Q69926294gamma-Carboxyglutamic acid

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