Molecular Mechanics of Translation : a Reciprocating Ratchet Mechanism

scientific article published on May 30, 1970

Molecular Mechanics of Translation : a Reciprocating Ratchet Mechanism is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1038/226817A0
P953full work available at URLhttp://www.nature.com/articles/226817a0
http://www.nature.com/articles/226817a0.pdf
P698PubMed publication ID5444622

P2093author name stringC. Woese
P2860cites workBulletin de la Societe de chimie biologiqueQ27710181
N-FORMYL-METHIONYL-S-RNAQ28156716
Comparison of guanosine triphosphate split and polypeptide synthesis with a purified E. coli systemQ33802996
Detailed molecular model for transfer ribonucleic acidQ34232522
Complementary Oligonucleotide Binding to the Anticodon Loop of fMet-transfer RNAQ34233056
Role of guanosine 5'-triphosphate in the initiation of Peptide synthesis, I. Synthesis of formylmethionyl-puromycinQ35970669
PHAGE f2 RNA-DIRECTED BINDING OF FORMYLMETHIONYL-TRNA TO RIBOSOMES AND THE ROLE OF 30S RIBOSOMAL SUBUNITS IN INITIATION OF PROTEIN SYNTHESISQ35976720
Conformational differences between the biologically active and inactive forms of a transfer ribonucleic acidQ36463732
Demonstration of a guanosine triphosphate-dependent enzymatic binding of aminoacyl-ribonucleic acid to Escherichia coli ribosomesQ36463978
Genetic Code: Aspects of OrganizationQ40035751
Polypeptidyl-sigma-ribonucleic acid and amino-acyl-sigma-ribonucleic acid binding sites on ribosomesQ44135267
Translation and translocation of defined RNA messengersQ47783915
Binding of Formylmethionyl-tRNA to 30S Ribosomal Sub-unitsQ47815333
Origin of the Genetic CodeQ58981583
Sequence Analysis of Specific Areas of the 16S and 23S Ribosomal RNAsQ59029882
Conformation of the Anticodon Loop in tRNAQ59034824
Arrangement of the Helical Regions in E. coli Tyrosine tRNAQ59041391
Coding properties of two conformations of tryptophanyl-tRNA in Escherichia coliQ69889387
Regulatory mechanisms and protein synthesis. X. Codon recognition on 30 S ribosomesQ71208767
Studies on polynucleotides. LXVII. Initiation of protein synthesis in vitro as studied by using ribopolynucleotides with repeating nucleotide sequences as messengersQ71212010
Catalysis of peptide bond formation by 50 s ribosomal subunits from Escherichia coliQ71213755
On the tertiary structure of transfer ribonucleic acidQ77921221
Polypeptide synthesis in Escherichia coli. II. The polypeptide chain and S-RNAQ79488388
Biosynthetic precursors of 30 S and 50 S ribosomal particles in Escherichia coliQ93811846
P433issue5248
P407language of work or nameEnglishQ1860
P921main subjectchemical modelQ25109595
P304page(s)817-820
P577publication date1970-05-01
1970-05-30
P1433published inNatureQ180445
P1476titleMolecular mechanics of translation: a reciprocating ratchet mechanism
Molecular Mechanics of Translation : a Reciprocating Ratchet Mechanism
P478volume226

Reverse relations

cites work (P2860)
Q40954673A Study of the Thermal Unfolding of Escherichia coli Phenylalanine Transfer RNA by Chemical Modification at Elevated Temperatures
Q74043666A code in the protein coding genes
Q56905719A conformational rationale for the origin of the mechanism of nucleicacid-directed protein synthesis of 'living' organisms
Q37116592A gripping tale of ribosomal frameshifting: extragenic suppressors of frameshift mutations spotlight P-site realignment
Q47860499A model for the development of genetic translation
Q54245189A model for the tertiary structure of tRNA
Q24561954A new biology for a new century
Q40573215A novel conformational change of the anticodon region of tRNAPhe(yeast)
Q29619258A ratchet-like inter-subunit reorganization of the ribosome during translocation
Q33860893A speculation on the origin of protein synthesis
Q36192838A spin label study of the thermal unfolding of secondary and tertiary structure in E.coli transfer RNAs
Q37480505A translocation-associated ribosomal conformational change detected by hydrogen exchange and sedimentation velocity
Q35026380Aminoacyl-tRNA binding at the recognition site is the first step of the elongation cycle of protein synthesis
Q52388461Analytical expression of the purine/pyrimidine codon probability after and before random mutations.
Q35590185Anticodon-anticodon interaction induces conformational changes in tRNA: yeast tRNAAsp, a model for tRNA-mRNA recognition
Q37397615Base substitutions in the tRNA anticodon arm do not degrade the accuracy of reading frame maintenance
Q24634337Before enzymes and templates: theory of surface metabolism
Q69242794Binding of complementary pentanucleotides to the anticodon loop of transfer RNA
Q41250363Bisulfite-induced C changed to U transitions in yeast alanine tRNA
Q38358841Bisulfite-induced C changed to U transitions in yeast valine tRNA
Q31529984Calculation of the relative geometry of tRNAs in the ribosome from directed hydroxyl-radical probing data
Q40382945Chemical modification as a probe of conformational changes in transfer ribonucleic acid on aminoacylation
Q69943199Circular dichroism during deacylation of methionyl-tRNAfmet and formylmethionyl-tRNAfmet from E. coli
Q36948473Codon recognition during frameshift suppression in Saccharomyces cerevisiae
Q41700577Codon-anticodon interaction at the ribosomal peptidyl-site
Q36405137Comparison of the structures of free and ribosome-bound tRNAPhe by using slow tritium exchange
Q38362413Complementary oligonucleotide binding to transfer RNA
Q35109347Conformation of Charged and Uncharged tRNA Phe
Q39935623Conformational States of Transfer Ribonucleic Acids
Q37473683Conformational changes in ribosomes during protein synthesis
Q36463111Conformational dynamics of the anticodon loop in yeast tRNAPhe as sensed by the fluorescence of wybutine
Q39844036Constraints on the accuracy of messenger RNA movement
Q40462470Crosslinking transfer RNA and messenger RNA at the ribosomal decoding region: identification of the site of reaction on the messenger RNA.
Q27639298Cryo-EM reveals an active role for aminoacyl-tRNA in the accommodation process
Q27678850Crystal Structures of EF-G-Ribosome Complexes Trapped in Intermediate States of Translocation
Q33721806Detailed analysis of the higher-order structure of 16S-like ribosomal ribonucleic acids
Q40464282Effect of ribosome binding and translocation on the anticodon of tRNAPhe as studied by wybutine fluorescence.
Q47782054Emergence of template-and-sequence-directed (TSD) syntheses: I. A bio-geochemical model
Q37336205Evidence from ultraviolet absorbance measurements for a codon-induced conformational change in lysine tRNA from Escherichia coli
Q44466748Evolution of nucleic acid replication: the possible role of simple repeating sequence polypeptides therein
Q93754740Evolution of the genetic code
Q34809895Evolutionary conservation of reactions in translation
Q50216198Four-base codons ACCA, ACCU and ACCC are recognized by frameshift suppressor sufJ
Q43523835Frameshift Suppression: a Nucleotide Addition in the Anticodon of a Glycine Transfer RNA
Q41541869High resolution phosphorus NMR spectroscopy of transfer ribonucleic acids
Q54514224Hypothesis: emergence of translation as a result of RNA helicase evolution.
Q39913907Inhibitors of t-RNA O-Methyltransferase as Possible Antineoplastic Agents
Q67252391Intrinsic asymmetry of oligomer transitions and biomolecular evolution
Q40099410Ligand-Induced Conformational Changes in Ribonucleic Acids
Q36405022Mechanism of translocation: relative arrangement of tRNA and mRNA on the ribosome.
Q39772461Mechanisms in Polypeptide Chain Elongation on Ribosomes
Q35325592Method to determine the reading frame of a protein from the purine/pyrimidine genome sequence and its possible evolutionary justification
Q37568398Molecular model of ribosome frameshifting
Q40109097Nearest-Neighbor Effects in the Structure and Function of Nucleic Acids
Q37686206Nucleotide sequence of a yeast Ty element: evidence for an unusual mechanism of gene expression
Q45836311On the evolution of ribosomal RNA.
Q40393286On the origin of the genetic code
Q53714625Orientation of double-helical segments in crystals of yeast phenylalanine transfer RNA
Q34873903Orientations of transfer RNA in the ribosomal A and P sites
Q28776301Origin of the genetic code: a testable hypothesis based on tRNA structure, sequence, and kinetic proofreading
Q71760798Partial Nuclease Digestion of Transfer Ribonucleic Acids and Aminoacylated Transfer Ribonucleic Acids
Q41636028Periodic correlations in DNA sequences and evidence suggesting their evolutionary origin in a comma-less genetic code
Q67006935Perspectives on Thermodynamics and the Origin of Life
Q39703735Precursor-specific nucleotide sequences can govern RNA folding
Q39852801Prediction of pairing schemes in RNA molecules-loop contributions and energy of wobble and non-wobble pairs
Q28655007Primal eukaryogenesis: on the communal nature of precellular States, ancestral to modern life
Q70760547RNA Polymerase: a model for rotational translocation
Q38362073Recognition in Nucleic Acids and the Anticodon Families
Q28728225Rhizome of life, catastrophes, sequence exchanges, gene creations, and giant viruses: how microbial genomics challenges Darwin
Q21134742Ribosomal history reveals origins of modern protein synthesis
Q37944676Ribosome gymnastics--degree of difficulty 9.5, style 10.0.
Q46504581Ribosome structural dynamics in translocation: yet another functional role for ribosomal RNA.
Q33560382Secondary structure adventures with Carl Woese
Q69942469Selective reaction of methoxyamine with cytosine bases in tyrosine transfer ribonucleic acid
Q70571203Speculations on the evolution of the genetic code III: The evolution of t-RNA
Q36188883Stacking of Crick Wobble pair and Watson-Crick pair: stability rules of G-U pairs at ends of helical stems in tRNAs and the relation to codon-anticodon Wobble interaction
Q69241860Structural elements and organization of the ancestral translational machinery
Q34426043Structural insights into translational fidelity
Q36313969Structural variability of tRNA: small-angle x-ray scattering of the yeast tRNAphe-Escherichia coli tRNAGlu2 complex
Q34052506Structure of yeast phenylalanine tRNA at 3 Å resolution
Q54039746Tertiary structure and function of transfer-RNA
Q39935584The Elongation Reactions in Protein Synthesis
Q40090925The Fidelity of Translation
Q56672594The Hypercycle
Q35984354The concept of RNA-assisted protein folding: the role of tRNA.
Q46055178The ribosome moves: RNA mechanics and translocation
Q47601982The ribotype theory on the origin of life
Q47996121The rotating ribosome: A gross mechanical model for translation
Q59068997The transorientation hypothesis for codon recognition during protein synthesis
Q45840730The use of bonding between tRNAs to implement early peptide synthesis
Q70264341Topological arrangement of two transfer RNAs on the ribosome. Fluorescence energy transfer measurements between A and P site-bound tRNAphe
Q47857111Translation: Till termination us do part
Q34332282Translation: in retrospect and prospect
Q46547306You tell Carl that some of my best friends are Eukaryotes: Carl R. Woese (1928–2012).
Q72132640mRNA translocation in protein biosynthesis: association constants related to the translocation process
Q33861143tRNA-tRNA interactions within cellular ribosomes
Q77147873tRNAs in the spotlight during protein biosynthesis

Search more.