Inhibition of HIV replication by CD8+ T cells correlates with CD4 counts and clinical stage of disease

scientific article published on 01 July 1994

Inhibition of HIV replication by CD8+ T cells correlates with CD4 counts and clinical stage of disease is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1111/J.1365-2249.1994.TB06581.X
P932PMC publication ID1534787
P698PubMed publication ID7518369

P2093author name stringA M Gómez
K L Rosenthal
F M Smaill
P2860cites workHIV infection is active and progressive in lymphoid tissue during the clinically latent stage of diseaseQ28267375
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CD8+ cell anti-HIV activity correlates with the clinical state of the infected individualQ34185306
Isolation of Lymphocytopathic Retroviruses from San Francisco Patients with AIDSQ34250436
CD8+ lymphocytes can control HIV infection in vitro by suppressing virus replicationQ34390292
CD8+ cell anti-HIV activity: nonlytic suppression of virus replicationQ35262596
A cytotoxic T lymphocyte inhibits acquired immunodeficiency syndrome virus replication in peripheral blood lymphocytesQ36356023
Cytotoxic T lymphocytes against HIVQ36578424
Inhibition of human immunodeficiency virus replication in acutely infected CD4+ cells by CD8+ cells involves a noncytotoxic mechanismQ36820948
Comparable sensitivities for detection of human immunodeficiency virus by sensitive reverse transcriptase and antigen capture enzyme-linked immunosorbent assaysQ37144165
Variable and conserved neutralization antigens of human immunodeficiency virusQ38891686
MHC-Restricted Cytotoxic T Cells: Studies on the Biological Role of Polymorphic Major Transplantation Antigens Determining T-Cell Restriction-Specificity, Function, and ResponsivenessQ39576364
Comparison of antigen assay and reverse transcriptase assay for detecting human immunodeficiency virus in culture.Q40209735
AIDS virus-specific cytotoxic T lymphocytes in lung disordersQ41447927
In vitro replication of HIV-1 in naturally infected CD4+ T cells is inhibited by rIFN alpha 2 and by a soluble factor secreted by activated CD8+ T cells, but not by rIFN beta, rIFN gamma, or recombinant tumor necrosis factor-alphaQ41707962
Activation of complement on the surface of cells infected by human immunodeficiency virusQ41744013
Inhibition of SIV/SMM replication in vitro by CD8+ cells from SIV/SMM infected seropositive clinically asymptomatic sooty mangabeysQ41757062
CD8+ T cells inhibit HIV replication in naturally infected CD4+ T cells. Evidence for a soluble inhibitorQ43730414
Reliable isolation of human immunodeficiency virus from cultures of naturally infected CD4+ T cellsQ43875706
A diffusible lymphokine produced by CD8+ T lymphocytes suppresses HIV replication.Q44141073
Suppression of human immunodeficiency virus replication by CD8+ cells from infected and uninfected chimpanzeesQ44246260
Antibody-dependent cellular cytotoxicity specific for the envelope antigens of human immunodeficiency virusQ44527640
CD8+ lymphocytes suppress HIV production by autologous CD4+ cells without eliminating the infected cells from cultureQ44905194
HIV-1 gag-specific cytotoxic T lymphocytes defined with recombinant vaccinia virus and synthetic peptidesQ45151315
Antibody-dependent cellular cytotoxicity-inducing antibodies against human immunodeficiency virus. Presence at different clinical stagesQ45831153
Suppression of simian immunodeficiency virus replication in vitro by CD8+ lymphocytesQ45839300
Antibodies to human immunodeficiency virus in human sera induce cell-mediated lysis of human immunodeficiency virus-infected cellsQ45842647
Activation of the complement system in human immunodeficiency virus infection: relevance of the classical pathway to pathogenesis and disease severityQ45853477
HIV replication can be blocked by recombinant human interferon beta.Q46031119
CD8+ T lymphocyte control of HIV replication in cultured CD4+ cells varies among infected individualsQ46442421
CD8+ T cells from HIV-1-infected individuals inhibit acute infection by human and primate immunodeficiency virusesQ46494799
HIV-infected humans, but not chimpanzees, have circulating cytotoxic T lymphocytes that lyse uninfected CD4+ cells.Q52848179
Mechanism of defective NK cell activity in patients with acquired immunodeficiency syndrome (AIDS) and AIDS-related complex. I. Defective trigger on NK cells for NKCF production by target cells, and partial restoration by IL 2.Q54478001
Human alpha- and beta-interferon but not gamma- suppress the in vitro replication of LAV, HTLV-III, and ARV-2.Q55244180
Phenotypic heterogeneity of cerebrospinal fluid-derived HIV-specific and HLA-restricted cytotoxic T-cell clonesQ58991727
Massive covert infection of helper T lymphocytes and macrophages by HIV during the incubation period of AIDSQ59057787
Recovery of AIDS-associated retroviruses from patients with AIDS or AIDS-related conditions and from clinically healthy individualsQ68943219
Evaluation of natural killer cell activity in patients with persistent generalized lymphadenopathy and acquired immunodeficiency syndromeQ69869521
An activated CD8+ T cell phenotype correlates with anti-HIV activity and asymptomatic clinical statusQ70489799
Lysis of CD4+ lymphocytes by non-HLA-restricted cytotoxic T lymphocytes from HIV-infected individualsQ72231557
P433issue1
P304page(s)68-75
P577publication date1994-07-01
P1433published inClinical and Experimental ImmunologyQ15716708
P1476titleInhibition of HIV replication by CD8+ T cells correlates with CD4 counts and clinical stage of disease
P478volume97