| scholarly article | Q13442814 |
| P356 | DOI | 10.1126/SCIENCE.6823558 |
| P698 | PubMed publication ID | 6823558 |
| P2093 | author name string | R S Sparkes | |
| L L Field | |||
| W F Benedict | |||
| A L Murphree | |||
| S J Funderburk | |||
| M C Sparkes | |||
| R W Lingua | |||
| P433 | issue | 4587 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | retinoblastoma | Q500695 |
| P304 | page(s) | 971-973 | |
| P577 | publication date | 1983-02-01 | |
| P1433 | published in | Science | Q192864 |
| P1476 | title | Gene for hereditary retinoblastoma assigned to human chromosome 13 by linkage to esterase D | |
| P478 | volume | 219 |
| Q68274853 | A "new" allele of esterase D in a retinoblastoma family |
| Q34192768 | A case report of a patient with retinoblastoma and chromosome 13q deletion: assignment of a new gene (gene for LCP1) on human chromosome 13. |
| Q34631552 | A continuum model for tumour suppression |
| Q53630492 | A detailed analysis of chromosomal changes in heritable and non-heritable retinoblastoma. |
| Q29618817 | A human DNA segment with properties of the gene that predisposes to retinoblastoma and osteosarcoma |
| Q53519285 | A human immunoglobulin gene reduces the incidence of lymphomas in c-Myc-bearing transgenic mice. |
| Q41445534 | A null allele of esterase D is a marker for genetic events in retinoblastoma formation |
| Q67957206 | A polymorphic region defined by pCN2 (the 3' nontranslated region of N-ras) maps to chromosome 9cen-p12 |
| Q35589883 | A sialic acid-specific O-acetylesterase in human erythrocytes: possible identity with esterase D, the genetic marker of retinoblastomas and Wilson disease |
| Q61647860 | A somatic cell hybrid map of human chromosome 13 |
| Q33825340 | Abnormalities in structure and expression of the human retinoblastoma gene in SCLC. |
| Q40542704 | Amplification and characterization of the retinoblastoma gene VNTR by PCR |
| Q39816011 | An appraisal of the application of recombinant DNA techniques to chromosome defects |
| Q36028754 | An assessment of the usefulness of electrophoretic variants of esterase-D in the antenatal diagnosis of retinoblastoma in the United Kingdom |
| Q33596814 | Application of PCR amplification of DNA from paraffin embedded tissue sections to linkage analysis in familial retinoblastoma |
| Q35066308 | Application of intragenic DNA probes in prenatal screening for retinoblastoma gene carriers in the United Kingdom. |
| Q37680904 | Assignment of the gene for Wilson disease to chromosome 13: linkage to the esterase D locus |
| Q47231040 | Autosomal dominant congenital cataract. Interocular phenotypic variability. |
| Q53559171 | Cancer genes in man. |
| Q42558312 | Causes of blindness in schoolchildren |
| Q35200618 | Chromosome 13 homozygosity in osteosarcoma without retinoblastoma |
| Q70184689 | Chromosome 13 restriction fragment length polymorphisms |
| Q39829565 | Clinical significance of esterases in man. |
| Q24630074 | Cloning of the esterase D gene: a polymorphic gene probe closely linked to the retinoblastoma locus on chromosome 13 |
| Q35811371 | Colonic aberrant crypts in azoxymethane-treated F344 rats have decreased hexosaminidase activity |
| Q35194318 | Constitutional 1p36 deletion in a child with neuroblastoma. |
| Q24314094 | Crystal structure of human esterase D: a potential genetic marker of retinoblastoma |
| Q39814516 | Current concepts on the biology of neuroblastoma |
| Q68839535 | De novo complex autosomal translocation involving chromosomes 8, 13 and 15 in a girl with a sporadic retinoblastoma |
| Q24304934 | Definition of the minimal simian virus 40 large T antigen- and adenovirus E1A-binding domain in the retinoblastoma gene product |
| Q69923674 | Deletion of chromosome region 13q14 is transmissible and does not always predispose to retinoblastoma |
| Q69996001 | Deletions of the esterase D locus from a survey of 200 retinoblastoma patients |
| Q69901151 | Detection of submicroscopic deletions and a DNA polymorphism at the retinoblastoma locus |
| Q59092304 | Development of homozygosity for chromosome 11p markers in Wilms' tumour |
| Q71326274 | Differential enzyme activities in human esterase D phenotypes |
| Q40212424 | Dominant susceptibility to cancer in man. |
| Q69241567 | Early diagnosis of retinoblastoma based on dysmorphic features and karyotype analysis |
| Q68742984 | Effect of the esterase-D phenotype on its in vitro enzyme activity |
| Q39462278 | Embryonal central neuroepithelial tumors: current concepts and future challenges |
| Q33848607 | Epigenetics, behaviour, and health |
| Q48409772 | Evidence for linkage between Wilson disease and esterase D in three kindreds: detection of linkage for an autosomal recessive disorder by the family study method |
| Q35200661 | Evidence for the close linkage between lymphocyte cytosol polypeptide with molecular weight of 64,000 (LCP1) and esterase D. |
| Q53480625 | Excess of multifocal tumors in nephroblastoma: implications for mechanisms of tumor development and genetic counseling. |
| Q41595912 | Expression and amplification of the N-myc gene in primary retinoblastoma |
| Q34264957 | Expression of recessive alleles by chromosomal mechanisms in retinoblastoma |
| Q69515778 | Extended polymorphism of the human esterase D isozyme system: description of a "new" allele EsD*11 |
| Q54133028 | Familial retinoblastoma (mother and son) with 13q14 deletion. |
| Q54504928 | Familial, EsD-linked, retinoblastoma with reduced penetrance and variable expressivity. |
| Q37734603 | Frequent inactivation of the retinoblastoma anti-oncogene is restricted to a subset of human tumor cells |
| Q47673133 | Gastrointestinal Malignancy: Genetic Implications to Clinical Applications |
| Q35197581 | Gene inactivation as a mechanism for the expression of recessive phenotypes |
| Q40141135 | Genes, chromosomes, and cancer |
| Q71326294 | Genetic analysis of human lymphocyte proteins by two-dimensional gel electrophoresis: VI. Identification of esterase D in the two-dimensional gel electrophoresis pattern of cellular proteins |
| Q38138544 | Genetic and epigenetic losses of heterozygosity in cancer predisposition and progression |
| Q33648550 | Genetic counselling in retinoblastoma: importance of ocular fundus examination of first degree relatives and linkage analysis |
| Q73019078 | Genetic epidemiology of childhood cancer |
| Q41084456 | Genetics and epidemiology of Wilms' tumor: The French Wilms' tumor study |
| Q40164274 | Genetics in Pediatric Ophthalmology |
| Q41461943 | Genetics of retinoblastoma: a study |
| Q40970549 | Hereditary cancer: two hits revisited |
| Q44901802 | Hereditary retinoblastoma: can balanced insertion entirely explain the differences of expressivity among families? |
| Q37941746 | Heterogeneity and natural history of hereditary breast cancer. Surgical implications |
| Q69900307 | History and present status of human chromosome studies |
| Q67671728 | Homozygous Deletion Within the Retinoblastoma Gene in a Native Osteosarcoma Specimen of a Patient Cured of a Retinoblastoma of Both Eyes |
| Q37371276 | How the Rb tumor suppressor structure and function was revealed by the study of Adenovirus and SV40. |
| Q24296960 | Human esterase D gene: complete cDNA sequence, genomic structure, and application in the genetic diagnosis of human retinoblastoma |
| Q33563547 | Human retinoblastoma susceptibility gene: genomic organization and analysis of heterozygous intragenic deletion mutants |
| Q40578218 | Immortalization in a normal foreskin fibroblast culture following transduction of cyclin A2 or cdk1 genes in retroviral vectors. |
| Q70741960 | Incidence and significance of a deletion of chromosome band 13q14 in patients with retinoblastoma and in their families |
| Q33570260 | Inheritance of human breast cancer: evidence for autosomal dominant transmission in high-risk families |
| Q69446171 | Interstitial deletion of chromosome 13 involving the region 13q14 |
| Q42546132 | Interstitial deletion of chromosome band 13q14 associated with squamous cell carcinoma. |
| Q89316321 | Introduction to special issue of Familial Cancer |
| Q57791572 | Isochromosome 6p, a unique chromosomal abnormality in retinoblastoma: Verification by standard staining techniques, new densitometric methods, and somatic cell hybridization |
| Q71274658 | Isoelectric focusing studies of human red cell esterase D: evidence for polymorphic occurrence of a new allele EsD7 in Japanese |
| Q36738419 | Isolation and characterisation of a panel of cosmids which allows unequivocal identification of chromosome deletions involving the RB1 gene using fluorescence in situ hybridisation |
| Q35199660 | Isolation and regional localization of DNA segments revealing polymorphic loci from human chromosome 13 |
| Q36593024 | Isolation of human chromosome 13-specific DNA sequences cloned from flow sorted chromosomes and potentially linked to the retinoblastoma locus |
| Q36415667 | Localization at a subband level of polymorphic 13q14 DNA probes for diagnosis of hereditary retinoblastoma and Wilson disease |
| Q35200606 | Localization of the human procollagen alpha 1(IV) gene to chromosome 13q34 by in situ hybridization |
| Q33671171 | Location of the retinoblastoma susceptibility gene(s) and the human esterase D locus. |
| Q34614026 | Loss of heterozygosity in human ductal breast tumors indicates a recessive mutation on chromosome 13 |
| Q33278871 | Loss of heterozygosity in the retinoblastoma tumor suppressor gene in skull base chordomas and chondrosarcomas |
| Q58348266 | Low incidence of deletion of the esterase D locus in retinoblastoma patients |
| Q68740851 | Malignant tumours generated by recessive mutations |
| Q35199131 | Mapping the Wilson disease locus to a cluster of linked polymorphic markers on chromosome 13. |
| Q71079120 | Medical genetics. Retinoblastoma and recessive alleles in tumorigenesis |
| Q34146103 | Meiotic segregation analysis of RB1 alleles in retinoblastoma pedigrees by use of single-sperm typing |
| Q28300083 | Microcytogenetics 1984 |
| Q70187705 | Model Hereditary Cancers of Man |
| Q40468269 | Molecular Genetics and Cytogenetics of Sarcomas |
| Q24630136 | Molecular cloning of the human esterase D gene, a genetic marker of retinoblastoma |
| Q69953882 | Molecular definition of the 11p15.5 region involved in Beckwith-Wiedemann syndrome and probably in predisposition to adrenocortical carcinoma |
| Q37401663 | Molecular detection of deletions involving band q14 of chromosome 13 in retinoblastomas |
| Q33919065 | Molecular evidence for putative tumour suppressor genes on chromosome 13q specific to BRCA1 related ovarian and fallopian tube cancer. |
| Q41406097 | Molecular evidence that the esterase-D gene lies proximal to the retinoblastoma susceptibility locus in chromosome region 13q14. |
| Q39701871 | Molecular genetic approaches to the analysis of human ophthalmic disease |
| Q33640362 | Molecular mechanism of retinoblastoma gene inactivation in retinoblastoma cell line Y79 |
| Q36827597 | Molecular mechanisms in lung pathogenesis |
| Q36464319 | Molecular mechanisms of oncogenic mutations in tumors from patients with bilateral and unilateral retinoblastoma |
| Q37938041 | Molecules, cancer, and the surgeon. A review of molecular biology and its implications for surgical oncology |
| Q35227325 | Multistage carcinogenesis in paediatric and adult cancers |
| Q40951665 | Mutation and cancer: a personal odyssey |
| Q39553062 | Ocular and orbital tumors. |
| Q37901169 | Oncogenes and growth factors in thyroid carcinogenesis. |
| Q44590170 | One allele deletion of the RB1 gene in a case of refractory anemia with del(13)(q12q14): a fluorescence in situ hybridization study of the RB1 gene |
| Q34003616 | One hit, two hits, three hits, more? Genomic changes in the development of retinoblastoma. |
| Q33605844 | Ophthalmology-important advances in clinical medicine: ophthalmic genetics: a new synthesis |
| Q37262104 | Opposing roles of pRB and p107 in adipocyte differentiation |
| Q37542430 | Osteosarcoma and retinoblastoma: a shared chromosomal mechanism revealing recessive predisposition |
| Q69928858 | Partial linkage map of chromosome 13q in the region of the Wilson disease and retinoblastoma genes |
| Q55062498 | Patient with 13 Chromosome Deletion: Evidence That the Retinoblastoma Gene Is a Recessive Cancer Gene |
| Q42410162 | Preimplantation genetic diagnosis for retinoblastoma predisposition |
| Q35977419 | Prophylactic retinal radiotherapy has an exceptional place in the management of familial retinoblastoma |
| Q24629865 | Purification, biochemical characterization, and biological function of human esterase D |
| Q72802833 | Putative non-Mendelian transmission of retinoblastoma in males: a phenotypic segregation analysis of 150 pedigrees |
| Q36468738 | Recessive Mutations in Cancer Predisposition and Progression |
| Q45819184 | Regulation of S-formylglutathione hydrolase by the anti-aging gene klotho |
| Q34559345 | Restriction fragment length polymorphism studies show consistent loss of chromosome 3p alleles in small cell lung cancer patients' tumors |
| Q37148255 | Retinoblastoma protein regulates the crosstalk between autophagy and apoptosis, and favors glioblastoma resistance to etoposide. |
| Q55261668 | Retinoblastoma--clinical and genetic aspects: a review. |
| Q34255360 | Retinoblastoma: Clues to Human Oncogenesis |
| Q41575472 | Retinoblastoma: a model of oncogenesis |
| Q36486953 | Role of the retinoblastoma gene in the oncogenesis of human breast carcinoma |
| Q70673831 | Separation of retinoblastoma and esterase D loci in a patient with sporadic retinoblastoma and del(13)(q14.1q22.3) |
| Q69894955 | Should all patients with retinoblastoma be screened for chromosome deletions? |
| Q72386147 | Solid tumors of children: Chromosome abnormalities and the development of cancer |
| Q57791580 | Somatic inactivation of genes on chromosome 13 is a common event in retinoblastoma |
| Q35200515 | The E7-associated cell-surface antigen: a marker for the 11p13 chromosomal deletion associated with aniridia-Wilms tumor. |
| Q40733277 | The cell cycle and the retinoblastoma protein family |
| Q70117697 | The genetics of retinoblastoma |
| Q40867777 | The molecular and genetic characterization of human soft tissue tumors. |
| Q39145519 | The molecular genetics of retinoblastoma and Wilms' tumor |
| Q35603433 | The need to screen all retinoblastoma patients for esterase D activity: detection of submicroscopic chromosome deletions |
| Q34193206 | The new biomedical technology. |
| Q30486894 | The ninth Gordon Hamilton-Fairley memorial lecture. Hereditary cancers: clues to mechanisms of carcinogenesis |
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| Q68047075 | Two new esterase D (ESD) variants revealed by isoelectric focusing in agarose gel |
| Q35833078 | Two types of putative preneoplastic lesions identified by hexosaminidase activity in whole-mounts of colons from F344 rats treated with carcinogen |
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