| scholarly article | Q13442814 |
| P356 | DOI | 10.1126/SCIENCE.6828889 |
| P698 | PubMed publication ID | 6828889 |
| P2093 | author name string | K J Kellar | |
| R D Schwartz | |||
| P433 | issue | 4593 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 214-216 | |
| P577 | publication date | 1983-04-01 | |
| P1433 | published in | Science | Q192864 |
| P1476 | title | Nicotinic cholinergic receptor binding sites in the brain: regulation in vivo | |
| P478 | volume | 220 |
| Q34109947 | 86Rb+ efflux mediated by alpha4beta2*-nicotinic acetylcholine receptors with high and low-sensitivity to stimulation by acetylcholine display similar agonist-induced desensitization |
| Q27335497 | A Two-Day Continuous Nicotine Infusion Is Sufficient to Demonstrate Nicotine Withdrawal in Rats as Measured Using Intracranial Self-Stimulation |
| Q73661239 | A comparison of the effects of nicotine on dopamine and non-dopamine neurons in the rat ventral tegmental area: an in vitro electrophysiological study |
| Q36077726 | AT-1001 Is a Partial Agonist with High Affinity and Selectivity at Human and Rat α3β4 Nicotinic Cholinergic Receptors |
| Q58790106 | Acetylcholine Neurotransmitter Receptor Densities in the Striatum of Hemiparkinsonian Rats Following Botulinum Neurotoxin-A Injection |
| Q43921757 | Acute nicotine effects on auditory sensory memory in tacrine-treated and nontreated patients with Alzheimer's disease: an event-related potential study |
| Q68020192 | Acute tolerance to the locomotor stimulant effects of nicotine in the rat |
| Q34266602 | Administration of the nicotinic acetylcholine receptor agonists ABT-089 and ABT-107 attenuates the reinstatement of nicotine-seeking behavior in rats. |
| Q36573029 | Adolescent nicotine exposure transiently increases high-affinity nicotinic receptors and modulates inhibitory synaptic transmission in rat medial prefrontal cortex |
| Q40101234 | Altered nicotine reward-associated behavior following α4 nAChR subunit deletion in ventral midbrain |
| Q44671836 | Attempts to visualize nicotinic receptors in the brain of monkey and man by positron emission tomography |
| Q43906380 | Behavioral activity and stereotypy in rats induced by L-DOPA metabolites: a possible role in the adverse effects of chronic L-DOPA treatment of Parkinson's disease |
| Q28534828 | Behavioral and molecular analysis of nicotine-conditioned place preference in zebrafish |
| Q39551988 | Biochemistry of nicotinic acetylcholine receptors in the vertebrate brain |
| Q42702006 | Blockade of nicotinic responses by physostigmine, tacrine and other cholinesterase inhibitors in rat striatum |
| Q41848840 | COPI polices nicotine-mediated up-regulation of nicotinic receptors |
| Q42173324 | Cell autonomy, receptor autonomy, and thermodynamics in nicotine receptor up-regulation |
| Q41987415 | Cellular and molecular mechanisms of drug dependence: An overview and update |
| Q37247103 | Cellular events in nicotine addiction |
| Q30422037 | Cellular, molecular, and genetic substrates underlying the impact of nicotine on learning |
| Q34002742 | Central nicotinic receptors, neurotrophic factors and neuroprotection |
| Q80388468 | Chemical medicine: novel 10-substituted cytisine derivatives with increased selectivity for alpha4beta2 nicotinic acetylcholine receptors |
| Q37259110 | Chemistry and pharmacological studies of 3-alkoxy-2,5-disubstituted-pyridinyl compounds as novel selective α4β2 nicotinic acetylcholine receptor ligands that reduce alcohol intake in rats |
| Q41234028 | Chronic corticosterone administration modulates nicotine sensitivity and brain nicotinic receptor binding in C3H mice |
| Q43970776 | Chronic ethanol or nicotine treatment results in partial cross-tolerance between these agents |
| Q33933568 | Chronic nicotine administration in the drinking water affects the striatal dopamine in mice |
| Q43616826 | Chronic nicotine and locomotor activity: influences of exposure dose and test dose |
| Q42516910 | Chronic nicotine cell specifically upregulates functional alpha 4* nicotinic receptors: basis for both tolerance in midbrain and enhanced long-term potentiation in perforant path. |
| Q35209160 | Chronic nicotine pretreatment is sufficient to upregulate α4* nicotinic receptors and increase oral nicotine self-administration in mice |
| Q36335508 | Chronic sazetidine-A at behaviorally active doses does not increase nicotinic cholinergic receptors in rodent brain. |
| Q37722609 | Chronic sazetidine-A maintains anxiolytic effects and slower weight gain following chronic nicotine without maintaining increased density of nicotinic receptors in rodent brain |
| Q36304857 | Chronic treatment with varenicline changes expression of four nAChR binding sites in mice |
| Q52228711 | Chronic treatments with cholinoceptor drugs influence spatial learning in rats. |
| Q30396291 | Cognitive deficits in schizophrenia: focus on neuronal nicotinic acetylcholine receptors and smoking |
| Q34444549 | Contribution of CNS nicotine metabolites to the neuropharmacological effects of nicotine and tobacco smoking |
| Q40388826 | Control of receptor sensitivity at the mRNA level |
| Q86716272 | Cortical excitability in smoking and not smoking individuals with and without nicotine |
| Q28506631 | Decreased signs of nicotine withdrawal in mice null for the beta4 nicotinic acetylcholine receptor subunit |
| Q46587041 | Deletion of the beta 2 nicotinic acetylcholine receptor subunit alters development of tolerance to nicotine and eliminates receptor upregulation |
| Q35073748 | Density of α4β2* nAChR on the surface of neurons is modulated by chronic antagonist exposure |
| Q37847449 | Desensitization of central cholinergic mechanisms and neuroadaptation to nicotine |
| Q34002779 | Development of ligands for in vivo imaging of cerebral nicotinic receptors |
| Q37995815 | Development of the motivational system during adolescence, and its sensitivity to disruption by nicotine. |
| Q51972766 | Different outcomes after acute and chronic treatment with nicotine in pre-pulse inhibition in Lister hooded rats. |
| Q40425965 | Differential Effect of Chronic Nicotine Treatment on Nicotinic Receptor Numbers in Various Brain Regions of Mice |
| Q44590890 | Differential Regulation of Nicotinic Acetylcholine Receptors in PC12 Cells by Nicotine and Nerve Growth Factor |
| Q42493545 | Differential alterations in nicotinic receptor alpha6 and beta3 subunit messenger RNAs in monkey substantia nigra after nigrostriatal degeneration |
| Q44735177 | Differential brain and peripheral nicotinic regulation of sympathoadrenal secretion. |
| Q89122894 | Differential effects of withdrawal from intermittent and continuous nicotine exposure on reward deficit and somatic aspects of nicotine withdrawal and expression of α4β2* nAChRs in Wistar male rats |
| Q40812551 | Discriminative stimulus (DS) properties of nicotine in the C57BL/6 mouse |
| Q30413744 | Dissociation of tolerance and nicotine withdrawal-associated deficits in contextual fear |
| Q39184374 | Distinct Roles of CREB Within the Ventral and Dorsal Hippocampus in Mediating Nicotine Withdrawal Phenotypes |
| Q37103329 | Divergent functional effects of sazetidine-a and varenicline during nicotine withdrawal. |
| Q44961442 | Effect of acute administration of nicotine on in vivo release of noradrenaline in the hippocampus of freely moving rats: A dose-response and antagonist study |
| Q48389875 | Effect of acute and chronic diisopropylfluorophosphate and atropine administration on somatostatin binding in the rat frontoparietal cortex and hippocampus |
| Q52597124 | Effect of nicotine and alpha-7 nicotinic modulators on visceral pain-induced conditioned place aversion in mice. |
| Q28345404 | Effect of nicotine on cerebellar granule neuron development |
| Q46692779 | Effect of nicotine on the release of acetylcholine and amino acids in the brain |
| Q37418492 | Effects of acute ultra-low dose mecamylamine on cognition in adult attention-deficit/hyperactivity disorder (ADHD). |
| Q33855077 | Effects of adolescent nicotine exposure and withdrawal on intravenous cocaine self-administration during adulthood in male C57BL/6J mice |
| Q35209455 | Effects of chronic nicotine on heteromeric neuronal nicotinic receptors in rat primary cultured neurons |
| Q53751185 | Effects of chronic oral nicotine treatment and its withdrawal on locomotor activity and brain monoamines in mice. |
| Q46560369 | Effects of nicotine on sensorimotor gating impairment induced by long-term treatment with neurotoxic NMDA antagonism |
| Q35562759 | Endogenously expressed muscarinic receptors in HEK293 cells augment up-regulation of stably expressed α4β2 nicotinic receptors |
| Q53197236 | Enhanced behavioral response to nicotine in an animal model of Alzheimer's disease. |
| Q21195727 | Evaluation of 18F-nifene binding to α4β2 nicotinic receptors in the rat brain using microPET imaging |
| Q37424588 | Evidence from mouse and man for a role of neuregulin 3 in nicotine dependence. |
| Q38950808 | Examination of the Involvement of Cholinergic-Associated Genes in Nicotine Behaviors in European and African Americans |
| Q47938136 | Genetic and environmental risk factors in Parkinson's disease |
| Q71690062 | Genetic association between cytochrome P450IA1 gene and susceptibility to Parkinson's disease |
| Q37126015 | Genetic background influences the effects of withdrawal from chronic nicotine on learning and high-affinity nicotinic acetylcholine receptor binding in the dorsal and ventral hippocampus |
| Q26853457 | Genetic matters: thirty years of progress using mouse models in nicotinic research |
| Q48394717 | Genetic polymorphism of paraoxonase 1 (PON1) and susceptibility to Parkinson's disease |
| Q99417452 | Hair cell α9α10 nicotinic acetylcholine receptor functional expression regulated by ligand binding and deafness gene products |
| Q39878966 | Hippocampal and striatal gray matter volume are associated with a smoking cessation treatment outcome: results of an exploratory voxel-based morphometric analysis |
| Q35353532 | Historical and current perspective on tobacco use and nicotine addiction |
| Q48439102 | Human tobacco smokers in early abstinence have higher levels of beta2* nicotinic acetylcholine receptors than nonsmokers. |
| Q42548131 | Hyperactivity induced by prenatal nicotine exposure is associated with an increase in cortical nicotinic receptors |
| Q36840066 | Impact of short access nicotine self-administration on expression of α4β2* nicotinic acetylcholine receptors in non-human primates |
| Q34715683 | Increased nicotinic acetylcholine receptor protein underlies chronic nicotine-induced up-regulation of nicotinic agonist binding sites in mouse brain |
| Q47856884 | Inducibility of c-Fos protein in visuo-motor system and limbic structures after acute and repeated administration of nicotine in the rat. |
| Q27010347 | Inside-out neuropharmacology of nicotinic drugs |
| Q26996794 | Interplay between smoking-induced genotoxicity and altered signaling in pancreatic carcinogenesis |
| Q36163922 | Involvement of cholinergic mechanisms in the behavioral effects of dietary fat consumption |
| Q52044821 | Is binding to nicotinic acetylcholine and dopamine receptors related to working memory in rats? |
| Q37728109 | Kinetics of desensitization and recovery from desensitization for human alpha4beta2-nicotinic acetylcholine receptors stably expressed in SH-EP1 cells |
| Q48786397 | Long-term ethanol treatment elicits changes in nicotinic receptor binding in only a few brain regions |
| Q37436125 | Lower ß2*-nicotinic acetylcholine receptor availability in smokers with schizophrenia |
| Q38727151 | Mapping of brain nicotinic receptors by autoradiographic techniques and the effect of experimental lesions. |
| Q84741046 | Mecamylamine elicits withdrawal-like signs in rats following a single dose of nicotine |
| Q28509139 | Mechanisms of inhibition and potentiation of α4β2 nicotinic acetylcholine receptors by members of the Ly6 protein family |
| Q90603824 | More than Smoke and Patches: The Quest for Pharmacotherapies to Treat Tobacco Use Disorder |
| Q38727137 | N-[3H]methylcarbamylcholine binding sites in the rat and human brain: relationship to functional nicotinic autoreceptors and alterations in Alzheimer's disease. |
| Q48623258 | Neonatal nicotine exposure induces permanent changes in brain nicotinic receptors and behaviour in adult mice |
| Q35566709 | Neural systems governed by nicotinic acetylcholine receptors: emerging hypotheses |
| Q91991315 | Neurobiological and Neurophysiological Mechanisms Underlying Nicotine Seeking and Smoking Relapse |
| Q37196810 | Neuronal Ca2+ sensor VILIP-1 leads to the upregulation of functional alpha4beta2 nicotinic acetylcholine receptors in hippocampal neurons |
| Q36137598 | Neuronal nicotinic acetylcholine receptors: neuroplastic changes underlying alcohol and nicotine addictions |
| Q34637004 | Neurophysiology of Nicotine Addiction |
| Q33596931 | Neurotransmitter system interactions revealed by drug-induced changes in motivated behavior |
| Q38608639 | Nicotine Addiction and Psychiatric Disorders |
| Q30560877 | Nicotine exploits a COPI-mediated process for chaperone-mediated up-regulation of its receptors. |
| Q47819976 | Nicotine exposure during adolescence: cognitive performance and brain gene expression in adult heterozygous reeler mice |
| Q37413060 | Nicotine is a selective pharmacological chaperone of acetylcholine receptor number and stoichiometry. Implications for drug discovery. |
| Q48819691 | Nicotine patches in Alzheimer's disease: Pilot study on learning, memory, and safety |
| Q28296049 | Nicotine psychopharmacology research contributions to United States and global tobacco regulation: a look back and a look forward |
| Q43581344 | Nicotine sensitization increases dendritic length and spine density in the nucleus accumbens and cingulate cortex |
| Q48151523 | Nicotine tolerance: an analysis of the time course of its development and loss in the rat. |
| Q34439566 | Nicotine up-regulates alpha4beta2 nicotinic receptors and ER exit sites via stoichiometry-dependent chaperoning |
| Q28139928 | Nicotine, brain nicotinic receptors, and neuropsychiatric disorders |
| Q34211873 | Nicotine-induced up regulation of α4β2 neuronal nicotinic receptors is mediated by the protein kinase c-dependent phosphorylation of α4 subunits |
| Q35777580 | Nicotine-induced upregulation of native neuronal nicotinic receptors is caused by multiple mechanisms |
| Q37525085 | Nicotine-induced upregulation of nicotinic receptors: underlying mechanisms and relevance to nicotine addiction |
| Q40504200 | Nicotine-related brain disorders: the neurobiological basis of nicotine dependence |
| Q40444567 | Nicotinic Receptors and Cholinergic Neurotransmission in the Central Nervous System |
| Q41659796 | Nicotinic acetylcholine receptors in health and disease |
| Q26782271 | Nicotinic acetylcholine receptors: upregulation, age-related effects and associations with drug use |
| Q53189482 | Nicotinic binding sites in cerebral cortex and hippocampus in Alzheimer's dementia. |
| Q36917265 | Nicotinic interactions with antipsychotic drugs, models of schizophrenia and impacts on cognitive function |
| Q34002764 | Nicotinic mechanisms involved in the dopamine activating and reinforcing properties of ethanol |
| Q48253277 | Nicotinic receptor binding sites in rat primary neuronal cells in culture: characterization and their regulation by chronic nicotine |
| Q38345702 | Nicotinic receptors, memory, and hippocampus |
| Q52081673 | Nicotinic systems and cognitive function |
| Q48118527 | PET studies of the uptake of (S)- and (R)-[11C]nicotine in the human brain: difficulties in visualizing specific receptor binding in vivo |
| Q48097853 | PPARα regulates cholinergic-driven activity of midbrain dopamine neurons via a novel mechanism involving α7 nicotinic acetylcholine receptors. |
| Q39810602 | Palmitoylation of nicotinic acetylcholine receptors |
| Q34406363 | Parallel anxiolytic-like effects and upregulation of neuronal nicotinic acetylcholine receptors following chronic nicotine and varenicline |
| Q38193225 | Pharmacological chaperoning of nAChRs: a therapeutic target for Parkinson's disease. |
| Q35996739 | Pharmacological chaperoning of nicotinic acetylcholine receptors reduces the endoplasmic reticulum stress response. |
| Q40955351 | Pharmacology of nicotine and its therapeutic use in smoking cessation and neurodegenerative disorders |
| Q96131645 | Polyamine regulation of ion channel assembly and implications for nicotinic acetylcholine receptor pharmacology |
| Q38016654 | Positron emission tomography and cholinergic mechanisms: an overview |
| Q39523317 | Prenatal adverse effects of nicotine on the developing brain |
| Q42469466 | Prolonged nicotine administration results in biphasic, brain-specific changes in kynurenate levels in the rat. |
| Q69389537 | Properties of putative nicotine receptors identified on cultured cortical neurons |
| Q52023506 | Protractive effects of chronic treatment with an acutely sub-toxic regimen of diisopropylflurophosphate on the expression of cholinergic receptor densities in rats. |
| Q34668336 | RIC-3 differentially modulates α4β2 and α7 nicotinic receptor assembly, expression, and nicotine-induced receptor upregulation |
| Q42652811 | Rapid upregulation of alpha7 nicotinic acetylcholine receptors by tyrosine dephosphorylation. |
| Q52166046 | Rats exhibiting acute behavioural tolerance to nicotine have more [125I]alpha-bungarotoxin binding sites in brain than rats not exhibiting tolerance. |
| Q31873474 | Receptor protection studies to characterize neuronal nicotinic receptors: tubocurarine prevents alkylation of adrenal nicotinic receptors |
| Q48324217 | Reduced α4 subunit expression in α4+- and α4+- /β2+- nicotinic acetylcholine receptors alters α4β2 subtype up-regulation following chronic nicotine treatment. |
| Q31362523 | Regional and cellular induction of nicotine-metabolizing CYP2B1 in rat brain by chronic nicotine treatment |
| Q42370644 | Regulation of nicotinic receptors in rat brain following quasi-irreversible nicotinic blockade by chlorisondamine and chronic treatment with nicotine |
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| Q36337926 | Regulation of α4β2α5 nicotinic acetylcholinergic receptors in rat cerebral cortex in early and late adolescence: Sex differences in response to chronic nicotine |
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| Q37024161 | Review. Neurobiology of nicotine dependence |
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| Q37272338 | Risk for nicotine dependence and lung cancer is conferred by mRNA expression levels and amino acid change in CHRNA5. |
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| Q30455930 | The duration of nicotine withdrawal-associated deficits in contextual fear conditioning parallels changes in hippocampal high affinity nicotinic acetylcholine receptor upregulation. |
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