The endothelin antagonist bosentan: hemodynamic effects during normoxia and hypoxic pulmonary hypertension in pigs

scientific article published on 01 October 1996

The endothelin antagonist bosentan: hemodynamic effects during normoxia and hypoxic pulmonary hypertension in pigs is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1016/S0022-5223(96)70088-0
P698PubMed publication ID8873714

P2093author name stringM Clozel
P Holm
A Franco-Cereceda
J Liska
P2860cites workThe human endothelin family: three structurally and pharmacologically distinct isopeptides predicted by three separate genesQ24339000
A novel potent vasoconstrictor peptide produced by vascular endothelial cellsQ29620540
Hypoxia induces endothelin gene expression and secretion in cultured human endotheliumQ34200622
Endothelin- and neuropeptide Y-induced vasoconstriction of human epicardial coronary arteries in vitroQ35756594
Pulmonary vasodilation to endothelin isopeptides in vivo is mediated by potassium channel activationQ44373602
Mechanism of endothelin-1-induced pulmonary vasoconstrictionQ44797061
Sarafotoxin S6c: An agonist which distinguishes between endothelin receptor subtypesQ48766674
Endothelin infusion reduces hypoxic pulmonary hypertension in pigs in vivo.Q51598687
Functional evidence for different endothelin receptors in the lung.Q51661126
Evidence for endothelin-1-mediated vasoconstriction in severe chronic heart failureQ53790656
Both ETA and ETB receptors mediate contraction to endothelin-1 in human blood vessels.Q54212669
Plasma endothelin levels and surgically correctable pulmonary hypertension.Q54248655
Increased plasma endothelin-1 in pulmonary hypertension: marker or mediator of disease?Q54299949
Endothelin-1 in pulmonary hypertension associated with high-altitude exposureQ57118235
Endothelin dilates bovine pulmonary circulation and reverses hypoxic pulmonary vasoconstrictionQ67539115
Endothelin as a putative sensory neuropeptide in the guinea-pig: different properties in comparison with calcitonin gene-related peptideQ67936609
Plasma endothelin concentrations in patients with pulmonary hypertension associated with congenital heart defects. Evidence for increased production of endothelin in pulmonary circulationQ68069838
Occurrence and effects of endothelin in guinea-pig cardiopulmonary tissueQ68517459
Immunoreactive endothelin in human plasma: marked elevations in patients in cardiogenic shockQ69509803
Relation of elevated plasma endothelin in congenital heart disease to increased pulmonary blood flowQ70676779
Endothelin receptor subtypes in human versus rabbit pulmonary arteriesQ72135800
Circulating immunoreactive endothelin-1 in children with pulmonary hypertension. Association with acute hypoxic pulmonary vasoreactivityQ72860769
P433issue4
P407language of work or nameEnglishQ1860
P921main subjectpulmonary hypertensionQ1128595
P304page(s)890-897
P577publication date1996-10-01
P1433published inThe Journal of Thoracic and Cardiovascular SurgeryQ2795598
P1476titleThe endothelin antagonist bosentan: hemodynamic effects during normoxia and hypoxic pulmonary hypertension in pigs
P478volume112