Peroxisome proliferator activated receptor alpha

mammalian protein found in Homo sapiens

Wikidata entity: Q7169506



P682 biological process ... Q210861 (cell differentiation) cell differentiation
P682 biological process ... Q411391 (regulation of gene expression) regulation of gene expression
P682 biological process ... Q1509074 (wound healing) wound healing
P682 biological process ... Q2792936 (lipid metabolism) lipid metabolism
P682 biological process ... Q471817 (development of the heart) development of the heart
P682 biological process ... Q828130 (signal transduction) signal transduction
P682 biological process ... Q14599765 (response to insulin) response to insulin
P682 biological process ... Q14633878 (negative regulation of transcription by RNA polymerase II) negative regulation of transcription by RNA polymerase II
P682 biological process ... Q14633883 (regulation of transcription, DNA-templated) regulation of transcription, DNA-templated
P682 biological process ... Q14633919 (negative regulation of transcription, DNA-templated) negative regulation of transcription, DNA-templated
P682 biological process ... Q14645705 (multicellular organism development) multicellular organism development
P682 biological process ... Q14763010 (transcription, DNA-templated) transcription, DNA-templated
P682 biological process ... Q14818066 (positive regulation of transcription, DNA-templated) positive regulation of transcription, DNA-templated
P682 biological process ... Q14818068 (positive regulation of transcription by RNA polymerase II) positive regulation of transcription by RNA polymerase II
P682 biological process ... Q14819239 (response to hypoxia) response to hypoxia
P682 biological process ... Q14819887 (negative regulation of blood pressure) negative regulation of blood pressure
P682 biological process ... Q14821398 (negative regulation of appetite) negative regulation of appetite
P682 biological process ... Q14859573 (hormone-mediated signaling pathway) hormone-mediated signaling pathway
P682 biological process ... Q14859853 (negative regulation of macrophage derived foam cell differentiation) negative regulation of macrophage derived foam cell differentiation
P682 biological process ... Q14860785 (transcription initiation from RNA polymerase II promoter) transcription initiation from RNA polymerase II promoter
P682 biological process ... Q14860867 (fatty acid metabolic process) fatty acid metabolic process
P682 biological process ... Q14861060 (negative regulation of inflammatory response) negative regulation of inflammatory response
P682 biological process ... Q14863096 (epidermis development) epidermis development
P682 biological process ... Q14863113 (negative regulation of neuron death) negative regulation of neuron death
P682 biological process ... Q14864471 (regulation of circadian rhythm) regulation of circadian rhythm
P682 biological process ... Q14864472 (rhythmic process) rhythmic process
P682 biological process ... Q14864580 (fatty acid transport) fatty acid transport
P682 biological process ... Q14864753 (lipoprotein metabolic process) lipoprotein metabolic process
P682 biological process ... Q14873002 (intracellular receptor signaling pathway) intracellular receptor signaling pathway
P682 biological process ... Q14873026 (steroid hormone mediated signaling pathway) steroid hormone mediated signaling pathway
P682 biological process ... Q14901701 (negative regulation of cell growth involved in cardiac muscle cell development) negative regulation of cell growth involved in cardiac muscle cell development
P682 biological process ... Q14902251 (response to lipid) response to lipid
P682 biological process ... Q14905380 (negative regulation of protein binding) negative regulation of protein binding
P682 biological process ... Q14906369 (regulation of lipid metabolic process) regulation of lipid metabolic process
P682 biological process ... Q14906412 (positive regulation of fatty acid beta-oxidation) positive regulation of fatty acid beta-oxidation
P682 biological process ... Q14908732 (circadian regulation of gene expression) circadian regulation of gene expression
P682 biological process ... Q14911770 (enamel mineralization) enamel mineralization
P682 biological process ... Q14913784 (regulation of fatty acid metabolic process) regulation of fatty acid metabolic process
P682 biological process ... Q14916150 (negative regulation of transcription regulatory region DNA binding) negative regulation of transcription regulatory region DNA binding
P682 biological process ... Q15318049 (negative regulation of cholesterol storage) negative regulation of cholesterol storage
P682 biological process ... Q15318051 (negative regulation of sequestering of triglyceride) negative regulation of sequestering of triglyceride
P682 biological process ... Q15318069 (positive regulation of fatty acid oxidation) positive regulation of fatty acid oxidation
P682 biological process ... Q21095272 (negative regulation of glycolytic process) negative regulation of glycolytic process
P682 biological process ... Q21111164 (behavioral response to nicotine) behavioral response to nicotine
P682 biological process ... Q21469789 (negative regulation of pri-miRNA transcription by RNA polymerase II) negative regulation of pri-miRNA transcription by RNA polymerase II
P682 biological process ... Q21499076 (negative regulation of leukocyte cell-cell adhesion) negative regulation of leukocyte cell-cell adhesion
P682 biological process ... Q22253774 (positive regulation of gluconeogenesis) positive regulation of gluconeogenesis
P681 cell component ... Q40260 (nucleus) nucleus
P681 cell component ... Q14817956 (nucleoplasm) nucleoplasm
P681 cell component ... Q21095257 (RNA polymerase II transcription regulator complex) RNA polymerase II transcription regulator complex
P702 encoded by ... Q18030677 (PPARA) PPARA
P703 found in taxon ... Q15978631 (Homo sapiens) Homo sapiens
P692 Gene Atlas image CommonsMedia http://commons.wikimedia.org/wiki/Special:FilePath/PBB%20GE%20PPARA%20206870%20at%20fs.png ???
P527 has part(s) ... Q24725588 (nuclear hormone receptor-type zinc finger) nuclear hormone receptor-type zinc finger
P527 has part(s) ... Q24772746 (Nuclear hormone receptor, ligand-binding domain) Nuclear hormone receptor, ligand-binding domain
P31 instance of ... Q8054 (protein) protein
P680 molecular function ... Q167149 (protein binding) protein binding
P680 molecular function ... Q13667380 (metal ion binding) metal ion binding
P680 molecular function ... Q14358833 (lipid binding) lipid binding
P680 molecular function ... Q14633858 (DNA binding) DNA binding
P680 molecular function ... Q14633865 (zinc ion binding) zinc ion binding
P680 molecular function ... Q14817973 (DNA-binding transcription activator activity, RNA polymerase II-specific) DNA-binding transcription activator activity, RNA polymerase II-specific
P680 molecular function ... Q14817979 (DNA-binding transcription factor activity) DNA-binding transcription factor activity
P680 molecular function ... Q14817982 (transcription factor binding) transcription factor binding
P680 molecular function ... Q14817995 (MDM2/MDM4 family protein binding) MDM2/MDM4 family protein binding
P680 molecular function ... Q14818107 (sequence-specific DNA binding) sequence-specific DNA binding
P680 molecular function ... Q14860851 (fatty acid binding) fatty acid binding
P680 molecular function ... Q14860854 (protein domain specific binding) protein domain specific binding
P680 molecular function ... Q14864645 (DNA-binding transcription factor activity, RNA polymerase II-specific) DNA-binding transcription factor activity, RNA polymerase II-specific
P680 molecular function ... Q14864804 (transcription cis-regulatory region binding) transcription cis-regulatory region binding
P680 molecular function ... Q14864823 (RNA polymerase II transcription regulatory region sequence-specific DNA binding) RNA polymerase II transcription regulatory region sequence-specific DNA binding
P680 molecular function ... Q14865333 (phosphatase binding) phosphatase binding
P680 molecular function ... Q14865608 (NFAT protein binding) NFAT protein binding
P680 molecular function ... Q14866186 (nuclear receptor coactivator activity) nuclear receptor coactivator activity
P680 molecular function ... Q14872988 (steroid hormone receptor activity) steroid hormone receptor activity
P680 molecular function ... Q14872989 (nuclear receptor activity) nuclear receptor activity
P680 molecular function ... Q14885806 (RNA polymerase II cis-regulatory region sequence-specific DNA binding) RNA polymerase II cis-regulatory region sequence-specific DNA binding
P680 molecular function ... Q21097436 (DNA-binding transcription repressor activity, RNA polymerase II-specific) DNA-binding transcription repressor activity, RNA polymerase II-specific
P680 molecular function ... Q21101580 (transcription coactivator binding) transcription coactivator binding
P680 molecular function ... Q21107991 (ubiquitin conjugating enzyme binding) ubiquitin conjugating enzyme binding
P680 molecular function ... Q21109843 (signaling receptor activity) signaling receptor activity
P680 molecular function ... Q22312857 (protein-containing complex binding) protein-containing complex binding
P361 part of ... Q24745994 (peroxisome proliferator-activated receptor alpha) peroxisome proliferator-activated receptor alpha
P361 part of ... Q24768526 (Zinc finger, NHR/GATA-type) Zinc finger, NHR/GATA-type
P361 part of ... Q41796865 (Nuclear hormone receptor-like domain superfamily) Nuclear hormone receptor-like domain superfamily
P361 part of ... Q83135095 (Zinc finger, nuclear hormone receptor-type, protein family) Zinc finger, nuclear hormone receptor-type, protein family
P361 part of ... Q83140722 (Nuclear hormone receptor, ligand-binding domain, protein family) Nuclear hormone receptor, ligand-binding domain, protein family
P129 physically interacts with ... Q384295 (gemfibrozil) gemfibrozil
P129 physically interacts with ... Q419724 (fenofibrate) fenofibrate
P129 physically interacts with ... Q2701912 (clofibrate) clofibrate
P129 physically interacts with ... Q3496452 (ciprofibrate) ciprofibrate
P129 physically interacts with ... Q577387 (bezafibrate) bezafibrate
P129 physically interacts with ... Q5435087 (farglitazar) farglitazar
P129 physically interacts with ... Q7086404 (oleic monoethanolamide) oleic monoethanolamide
P129 physically interacts with ... Q7198008 (pirinixic acid) pirinixic acid

External Ids
P705Ensembl protein IDENSP00000385246
P705Ensembl protein IDENSP00000411677
P705Ensembl protein IDENSP00000262735
P705Ensembl protein IDENSP00000414752
P705Ensembl protein IDENSP00000397291
P705Ensembl protein IDENSP00000385523
P638PDB structure ID1KKQ
P638PDB structure ID2NPA
P638PDB structure ID2P54
P638PDB structure ID3VI8
P638PDB structure ID3ET1
P638PDB structure ID3KDU
P638PDB structure ID2REW
P638PDB structure ID4CI4
P638PDB structure ID3G8I
P638PDB structure ID3KDT
P638PDB structure ID3FEI
P638PDB structure ID1I7G
P638PDB structure ID3SP6
P638PDB structure ID1K7L
P638PDB structure ID4BCR
P638PDB structure ID5AZT
P638PDB structure ID2ZNN
P637RefSeq protein IDNP_001001928
P637RefSeq protein IDNP_001349801
P637RefSeq protein IDNP_001349802
P637RefSeq protein IDNP_005027
P637RefSeq protein IDXP_005261713
P637RefSeq protein IDXP_006724333
P637RefSeq protein IDXP_011528541
P637RefSeq protein IDXP_011528542
P637RefSeq protein IDXP_011528543
P637RefSeq protein IDXP_011528544
P637RefSeq protein IDXP_011528545
P637RefSeq protein IDXP_011528546
P637RefSeq protein IDXP_011528547
P637RefSeq protein IDXP_016884328
P637RefSeq protein IDXP_024308020
P637RefSeq protein IDXP_024308021
P352UniProt protein IDQ07869

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